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TALSADERQELAQSVRSACERLASEDRVRAVAYAEGNRGGGDGHSGFDTVLWDVLCNQVGVAGIALPEHL GGAGYGVSALGVVAHELGRALAPVPFVGSTVLATGLLLDLTERDPDADKRLTGLIEGRRTAAAALTGDGG LWRRSAVTLRAARAGDDWNIDGTVRHVLGGSVADDLVVVAIDEDGEPAVFLLDPTIDSVVAEAERVLDRT RPMATITLSSAPALRLSGDAPLGDVVDRNVDIALAVLSAEQVGACERVLEIATDYARTREQFGRQIGSFQ AIKHKCADMLVDLEWARSASQAALEALDDPDSAAAGEAGWRASMAKAVCSEALRNATKANVQIHGGIGFT WEDSAHLYFRRARTDEVLLGAPGQHWDRLSTLDPSTQPPASPEVTKELNDVDALRAEIRSFLDNAPRPAG LRNYGPTPTADDVEAGRVWHRYLADHGYACLHWPREFGGAAATVTYQAVFAEECARAEVPRQVNITGADL VGPVLIKFGSQEQKDRYLEPIRLGDDVWCQLFSEPGAGSDLAGVRTRAERTTTGWRIDGQKVWSSAAASA RFGLLLARTGPDKHRDLSMFVVPMDIPGVTVRPLTQMDGESKFNEVFFDGAELDEDALIGEVGQGWTVAM VTLGRERLTLGSQAVSMFRLHERMVDAARDHDLLDPVLSRSMTRLWARMWLLRFTWQRAIDSGDLTSPAF SVLKLMTSETDQDLGDMATEVLGTDACTDPEEDGLVHHMLIGRAQTILGGTSEIQRNILGERVLGLPKEP R*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2570 | - | - | 100% (772) | putative acyl-CoA dehydrogenase |
| M. avium 104 | MAV_1835 | - | 0.0 | 80.53% (380) | acyl-CoA dehydrogenase protein |
| M. avium 104 | MAV_1838 | - | e-148 | 71.05% (380) | acyl-CoA dehydrogenase protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0277c | fadE6 | 1e-98 | 34.52% (785) | acyl-CoA dehydrogenase FADE6 |
| M. gilvum PYR-GCK | Mflv_0441 | - | 1e-102 | 35.73% (778) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv0271c | fadE6 | 1e-98 | 34.52% (785) | acyl-CoA dehydrogenase FADE6 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 8e-22 | 32.20% (205) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4336 | - | 1e-102 | 35.50% (738) | acyl-CoA dehydrogenase FadE |
| M. marinum M | MMAR_0530 | fadE6 | 3e-99 | 35.23% (789) | acyl-CoA dehydrogenase FadE6 |
| M. smegmatis MC2 155 | MSMEG_0603 | - | 1e-100 | 34.79% (779) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_4597 | - | 1e-173 | 77.60% (384) | PUTATIVE acyl-CoA dehydrogenase protein |
| M. ulcerans Agy99 | MUL_1194 | fadE6 | 2e-99 | 35.11% (789) | acyl-CoA dehydrogenase FadE6 |
| M. vanbaalenii PYR-1 | Mvan_0226 | - | 7e-99 | 34.61% (786) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2570|M.avium_104 -----------MTALSADERQELAQSVRSACERLASEDRVRAVAYAEGNR
TH_4597|M.thermoresistible__bu --------------------------------------------------
Mb0277c|M.bovis_AF2122/97 -----------MSIAITPEHYELADSVRSLVARVAPSEVLHAALESPVE-
Rv0271c|M.tuberculosis_H37Rv -----------MSIAITPEHYELADSVRSLVARVAPSEVLHAALESPVE-
MMAR_0530|M.marinum_M -----------MPIAITPEHRDLADSVRSLVARVAPSEVLHAAMETPVE-
MUL_1194|M.ulcerans_Agy99 -----------MPIAITPEHRDLADSVRSLVARVAPSEVLHAAMETPVE-
MSMEG_0603|M.smegmatis_MC2_155 -----------MPIAILSEHIDLADSVKSFVARVAPSDVLHEALETPLET
MAB_4336|M.abscessus_ATCC_1997 -----------MPIAINSEHVALADSAHAFVERVVPTELLHETLETPLP-
Mflv_0441|M.gilvum_PYR-GCK MSKTAS----ASKLAITDDHQDLAAAVTGQLDRLKALVLARATLDAADTD
Mvan_0226|M.vanbaalenii_PYR-1 MSKTVSATVTASRLAITDDHQDLAAAVSGQLTRLQTPAKARAALAG----
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
MAV_2570|M.avium_104 GGGDGHSGFDTVLWDVLCNQVGVAGIALPEHLGGAGYGVSALGVVAHELG
TH_4597|M.thermoresistible__bu --------------------------------------------------
Mb0277c|M.bovis_AF2122/97 ---------NPPPYWQAAAEQGLQGVHLAESVGGQGFGILELAVVLAEFG
Rv0271c|M.tuberculosis_H37Rv ---------NPPPYWQAAAEQGLQGVHLAESVGGQGFGILELAVVLAEFG
MMAR_0530|M.marinum_M ---------NPPPYWQAAAEQGLQGVHLAESVGGQGYGILELAVALAEFG
MUL_1194|M.ulcerans_Agy99 ---------NPPPYWQAAAEQGLQGVHLAESVGGQGYGILQLAVALAEFG
MSMEG_0603|M.smegmatis_MC2_155 ------PRANPPSYWKAAADQGLQGVHLSESVGGQGFGILELAIVLAEFG
MAB_4336|M.abscessus_ATCC_1997 ---------WPPPFWKSAADQGLTSVHLAESVGGQGFGALELAIVVAEFG
Mflv_0441|M.gilvum_PYR-GCK ------GASNPSDLWSAATGLGWTGLALAEDVGGSGFGLAELAVVVECLG
Mvan_0226|M.vanbaalenii_PYR-1 ------GSTHPADIWSAATELGWTGLALPEDVGGSGFGLEELAVVIECLG
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
MAV_2570|M.avium_104 RALAPVPFVGSTVLATGLLLDLTERDPDADKRLTGLIEGRRTAAAALTGD
TH_4597|M.thermoresistible__bu --------------------------------------------------
Mb0277c|M.bovis_AF2122/97 YGAVPGPFVPSAIAS--ALIAAHDPQ---AKVLAELATGAAIAAYALDSG
Rv0271c|M.tuberculosis_H37Rv YGAVPGPFVPSAIAS--ALIAAHDPQ---AKVLAELATGAAIAAYALDSG
MMAR_0530|M.marinum_M YGAVPGPFVPSAIAS--ALISVHDPE---AKVLSELASGAAIAAYALDSG
MUL_1194|M.ulcerans_Agy99 YGAVPGPFVPSAIAS--ALISVHDPE---AKVLSELASGAAISAYALDSG
MSMEG_0603|M.smegmatis_MC2_155 YGAVPGPFVPSAIAS--ALISAHDPD---AKVLSELASGDAIAAYALDST
MAB_4336|M.abscessus_ATCC_1997 RGAVPGPFVPSVIAS--ALISAHDPD---HPLLSDLASGASIATFSSTSS
Mflv_0441|M.gilvum_PYR-GCK HQLAPGPFLTSVSAA--VVIDRCAPDSVRAELLPGSASGDTVAALGISGT
Mvan_0226|M.vanbaalenii_PYR-1 SQLAPGPFLSSAAAS--VVIDRSAPDSVRAELLPVLAGGETVAALGVSGS
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
MAV_2570|M.avium_104 GGLWRRSAVTLRAARAGDDWNIDGTVRHVLGGSVADDLVVVAIDEDGEPA
TH_4597|M.thermoresistible__bu --------------------------------------------------
Mb0277c|M.bovis_AF2122/97 LTATRH----------GDVLVIRGEVRAVPAAAQASVLVLPVAIESRDEW
Rv0271c|M.tuberculosis_H37Rv LTATRH----------GDVLVIRGEVRAVPAAAQASVLVLPVAIESRDEW
MMAR_0530|M.marinum_M LTATRQGLE------DGGVLVIRGEVRAVPAAAQASILVLPVAIDSGDEW
MUL_1194|M.ulcerans_Agy99 LTATRQGLE------DGGVLVIRGEVRAVPAAAQASTLVLPVAIDSGGEW
MSMEG_0603|M.smegmatis_MC2_155 LTATRQ----------GDGLVIRGEVRAVPAAAQASILVLPVAIDSGEEW
MAB_4336|M.abscessus_ATCC_1997 FTATPA----------GDGLSVDGQARSVLSATSATYVVAPVAIDSDRRW
Mflv_0441|M.gilvum_PYR-GCK VAVGAD-------------NTATGECATVLGAPDASLLVL----VAGDDV
Mvan_0226|M.vanbaalenii_PYR-1 VVVGTD-------------LIVSGESPVVLAAPDASVLVL----TAGEDV
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
MAV_2570|M.avium_104 VFLLDP---TIDSVVAEAERVLDRTRPMATITLSSAPALRLSGDAPLGDV
TH_4597|M.thermoresistible__bu --------------------------------------------------
Mb0277c|M.bovis_AF2122/97 VVLRND------QLEIEAVKSLDPLRPIAHVRANAVDVS--DDALLSNLT
Rv0271c|M.tuberculosis_H37Rv VVLRND------QLEIEAVKSLDPLRPIAHVRANAVDVS--DDALLSNLT
MMAR_0530|M.marinum_M VVLRAE------QLEIEPVRSLDPLRPVAHVRANAVEVG--DDVVLSNLS
MUL_1194|M.ulcerans_Agy99 VVLRAE------QLEIEPVRSLDPLRPVAHVRANAVEVG--DDVVLSNLS
MSMEG_0603|M.smegmatis_MC2_155 VVLDAD------QLEIEPVRSVDPLRPLAHVRANAVEVA--DERVLSNLS
MAB_4336|M.abscessus_ATCC_1997 VVLSAD------DVTLDSQQSVDPLRPVAHVTATAVQVP--ADRVLSNLT
Mflv_0441|M.gilvum_PYR-GCK VIVDAG----DDGVTVTRLDCLDTTRSIGSVTLDGVAVP--ADRILRGAA
Mvan_0226|M.vanbaalenii_PYR-1 VILDAGPASAAGGVTVTPLDCLDPTRSIGSVTLRDVPVA--ADRVLRGAA
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
MAV_2570|M.avium_104 VDRNVDIALAVLSAEQVGACERVLEIATDYARTREQFGRQIGSFQAIKHK
TH_4597|M.thermoresistible__bu --------------------------------------------------
Mb0277c|M.bovis_AF2122/97 MTTAHALMSTLLSAEAVGVARWATDTASAYAKIREQFGRPIGQFQAIKHK
Rv0271c|M.tuberculosis_H37Rv MTTAHALMSTLLSAEAVGVARWATDTASAYAKIREQFGRPIGQFQAIKHK
MMAR_0530|M.marinum_M MTTAHALMSTLLSAEAVGVARWATDAASGYAKIREQFGRPIGQFQAIKHK
MUL_1194|M.ulcerans_Agy99 MTTAHALMSTLLSAEAVGVARWATDAASGYAKIREQFGRPIGQFQAIKHK
MSMEG_0603|M.smegmatis_MC2_155 RPLARALMSTLLSAESIGVARWATDTAAGYAKIREQFGRPIGQFQAVKHK
MAB_4336|M.abscessus_ATCC_1997 DARATSIISTIVSAEAVGVARWATDTASEYAKVREQFGRPIGQFQGIKHK
Mflv_0441|M.gilvum_PYR-GCK R-DARTVFRTLTAAEAVGVSWAALDMAVEYAKVREQFGRTIGTFQAVKHH
Mvan_0226|M.vanbaalenii_PYR-1 R-NARTVFRILAAAEAVGVSWAALDMAVGYAKVREQFGRTIGTFQAVKHH
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
MAV_2570|M.avium_104 CADMLVDLEWARSASQAALEALDDPDSAAAG--EAGWRASMAKAVCSEAL
TH_4597|M.thermoresistible__bu --------------------------------------------------
Mb0277c|M.bovis_AF2122/97 CAEMIADTERATAAVWDAARALDDAGESSSD---VEFAAAVAATLAPATA
Rv0271c|M.tuberculosis_H37Rv CAEMIADTERATAAVWDAARALDDAGESSSD---VEFAAAVAATLAPATA
MMAR_0530|M.marinum_M CAEMIADTERATAAVWDAARALD---EDSPH---IEFAAAVAATLAPAAA
MUL_1194|M.ulcerans_Agy99 CAEMIADTERATAAVWDAARALD---EDSPH---IEFAAAVAATLAPAAA
MSMEG_0603|M.smegmatis_MC2_155 CANMVAVTERATAAVWDAARALDEVREKGTEGTHFGFAAAVAATLAPAAA
MAB_4336|M.abscessus_ATCC_1997 CATMAAVTERATAAVWDAARALDDADENPGV---VEFAASVAATLAPAAA
Mflv_0441|M.gilvum_PYR-GCK AANMLVSAETATAAVWDAARADD---VDSAW-----FAAAVAAALAIKAQ
Mvan_0226|M.vanbaalenii_PYR-1 AANMLVAAEVATAATWDAARADD---LDSAW-----FAGAVAAALAIRAQ
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
MAV_2570|M.avium_104 RNATKANVQIHGGIGFTWEDSAHLYFRRARTDEVLLGAPGQHWDRLSTLD
TH_4597|M.thermoresistible__bu ------------------------------------------------VT
Mb0277c|M.bovis_AF2122/97 QRCTQDCIQVHGGIGFTWEHDTNVYYRR------------------ALML
Rv0271c|M.tuberculosis_H37Rv QRCTQDCIQVHGGIGFTWEHDTNVYYRR------------------ALML
MMAR_0530|M.marinum_M QRCTQDCIQVHGGIGYTWEHDTNVYYRR------------------ALML
MUL_1194|M.ulcerans_Agy99 QRCTQDCIQVHGGIGYTWEHDTNVYYRR------------------ALML
MSMEG_0603|M.smegmatis_MC2_155 QQCTQDCIQVHGGIGFTWEHDTNVYYRR------------------ALLL
MAB_4336|M.abscessus_ATCC_1997 QQCAQDCIQVHGGIGYTWEHDAHIYYRR------------------ALGL
Mflv_0441|M.gilvum_PYR-GCK VFNAQNNIQLHGGIGFTWEHDAHLYLRR------------------ARTL
Mvan_0226|M.vanbaalenii_PYR-1 VFNAQNNIQLHGGIGFTWEHDSHLYLRR------------------ARTL
MLBr_00737|M.leprae_Br4923 -------------------------------------------------M
MAV_2570|M.avium_104 PSTQPPASPEVTKELNDVDALRAEIRSFLDNAPRPAGLRNYGPTPTADDV
TH_4597|M.thermoresistible__bu ITDNGPAS------TDSLGDLRAKFRDFLADAPKPAGLRNYGPTPTADDI
Mb0277c|M.bovis_AF2122/97 AACFGRGSEYPQRVVDTATTAGMRPVDIDLDPSTEKLRAQIRAEVAALKA
Rv0271c|M.tuberculosis_H37Rv AACFGRGSEYPQRVVDTATTAGMRPVDIDLDPSTEKLRAQIRAEVAALKA
MMAR_0530|M.marinum_M AACFGRSVEYPQRVVDTATTTGMRAVDIDLDPDTEKLRAEIRADVEALKR
MUL_1194|M.ulcerans_Agy99 AACFGRSVEYPQRVVDTATTTGMRAVDIDLDPDTEKLRAEIRADVEALKR
MSMEG_0603|M.smegmatis_MC2_155 AACFGRAADHPQQVVDTATATGMRPVDIDLDPETEKLRDEIRAEVAALKA
MAB_4336|M.abscessus_ATCC_1997 TAALGRSGGAPATVVRTAVEHGLRKVDIDLAPETEALRAEIRAEVAALKE
Mflv_0441|M.gilvum_PYR-GCK AALMADGVDPLIDIVDGQRTGRAHGASFTLPPEADEYRTQAREAAEAVRR
Mvan_0226|M.vanbaalenii_PYR-1 AALMADGVDPLLDIVDGQRNGRAHGASFTLPPESEEYRSQAREAAAKVRS
MLBr_00737|M.leprae_Br4923 VGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAP------HAADVDQRA
:
MAV_2570|M.avium_104 EAGRVWHRYLADHGYACLHWPREFGGAAATVTYQAVFAEECARAEVPRQV
TH_4597|M.thermoresistible__bu EPGRAWHKYLADHGYVCLHWPREYGGADAPVAFQAAFAEECARAGVPRQL
Mb0277c|M.bovis_AF2122/97 MPREPRTVAIAEGGWVLPYLPKPWG-RAASPVEQIIIAQEFTAGRVKRPQ
Rv0271c|M.tuberculosis_H37Rv MPREPRTVAIAEGGWVLPYLPKPWG-RAASPVEQIIIAQEFTAGRVKRPQ
MMAR_0530|M.marinum_M MDREPRKAAIAEGGWVLPYLPKPWG-RASSPVEQVIIAQEFSTGRVKRPQ
MUL_1194|M.ulcerans_Agy99 MDREPRKAAIAEGGWVLPYLPKPWG-RASSPVEQVIIAQEFSTGRVKRPQ
MSMEG_0603|M.smegmatis_MC2_155 IPSEERTAAIAEGGWVQPHLPKPWG-RDATPVEQIIIAQEFTTGRVKRPQ
MAB_4336|M.abscessus_ATCC_1997 IPSGKRNTAIAEGGWVLPYLPTPWG-RAASPVEQVIISQEFLTGKVRRPQ
Mflv_0441|M.gilvum_PYR-GCK LPAEQQRDYLVDSGYLVPHWPKPWG-RAADVLEQLVIEEEFAA--IERAD
Mvan_0226|M.vanbaalenii_PYR-1 LPAGQQRDFLVESGYLVPHWPQPWG-RAANVLEQLVIEEEFAG--VDRPD
MLBr_00737|M.leprae_Br4923 RFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASL
: *: : * :* : . :*
MAV_2570|M.avium_104 NITGADLVGPVLIKFGSQEQKDRYLEPIRLGDDVWCQLFSEPGAGSDLAG
TH_4597|M.thermoresistible__bu AITAIDLVGPVLIKFGTDEQKARYLEPIRLGDHVWTQLFSEPGAGSDLAG
Mb0277c|M.bovis_AF2122/97 -IAIATWIVPSIVAFGTDNQKQRLLPPTFRGDIFWCQLFSEPGAGSDLAS
Rv0271c|M.tuberculosis_H37Rv -IAIATWIVPSIVAFGTDNQKQRLLPPTFRGDIFWCQLFSEPGAGSDLAS
MMAR_0530|M.marinum_M -VGIAAWILPSIVAFGTEEQKQRFLPPTFRGEMIWCQLFSEPGAGSDLAG
MUL_1194|M.ulcerans_Agy99 -VGIAAWILPSIVAFGTEEQKQRFLPPTFRGEMIWCQLFSEPGAGSDLAG
MSMEG_0603|M.smegmatis_MC2_155 -MGIASWIIPSIVAFGTDEQKQRFLPPTFRGEMIWCQLFSEPGAGSDLAS
MAB_4336|M.abscessus_ATCC_1997 -LGIATWLVPSIVAYGTEEQKQRFLPPTFRGEMMWCQLFSEPGAGSDLAG
Mflv_0441|M.gilvum_PYR-GCK -MGITGWVALTIAQAGTDEQRERWVEPVLRGQVMWCQLFSEPGAGSDAAA
Mvan_0226|M.vanbaalenii_PYR-1 -MGITGWVALTIAQAGTDDQRERWVEPVLRGQVMWCQLFSEPGAGSDAAA
MLBr_00737|M.leprae_Br4923 IPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAAS
: *::: : : : . . :** **** *.
MAV_2570|M.avium_104 VRTRAERTTTGWRIDGQKVWSSAAASARFGLLLARTGPDK--HRDLSMFV
TH_4597|M.thermoresistible__bu VRTRAEKTDTGWRINGQKVWSSAANSADYGLLLARTGPDS--HRGLSMFI
Mb0277c|M.bovis_AF2122/97 LATKATRVDGGWRITGQKIWTTGAQYSQWGALLARTDPSAPKHNGITYFL
Rv0271c|M.tuberculosis_H37Rv LATKATRVDGGWRITGQKIWTTGAQYSQWGALLARTDPSAPKHNGITYFL
MMAR_0530|M.marinum_M LSTKATRVDGGWRITGQKIWTTAAQYSQWGALLARTDPNAPKHNGITYFL
MUL_1194|M.ulcerans_Agy99 LSTKATRVDGGWRITGQKIWTTAAQYSQWGALLARTDPNAPKHNGITYFL
MSMEG_0603|M.smegmatis_MC2_155 LTTRAVKVDGGWRITGQKIWTTGAQFSAWGALLARTDPDAPKHQGITYFL
MAB_4336|M.abscessus_ATCC_1997 LSTKAVKVEGGWRLTGQKIWTSVAQFADWGACLARTDPSAPKHNGITYFL
Mflv_0441|M.gilvum_PYR-GCK VRTSAKKVDGGWRVTGQKVWTSLAHMCQWGLATVRTDPDAAKHAGVTMMA
Mvan_0226|M.vanbaalenii_PYR-1 VRTSAKKVDGGWRVTGQKVWTSLAHLCQWGLATVRTDPDAPKHAGVTMMA
MLBr_00737|M.leprae_Br4923 MRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKG-ANGISAFI
: * * .* : * * * : . . : . *.*. .:: :
MAV_2570|M.avium_104 VPMDIPGVTVRPLTQMDGE--SKFNEVFFDGAELDEDALIGEVGQGWTVA
TH_4597|M.thermoresistible__bu VPMDADGVSVRPLKQMDGE--SKFNEVFLDNVELPDDAIIGEPGQGWTIA
Mb0277c|M.bovis_AF2122/97 LDMKSEGVQVKPLRELTGK--EFFNTVYLDDVFVPDELVLGEVNRGWEVS
Rv0271c|M.tuberculosis_H37Rv LDMKSEGVQVKPLRELTGK--EFFNTVYLDDVFVPDELVLGEVNRGWEVS
MMAR_0530|M.marinum_M LDMKSEGVQVKPLRELTGH--EMFNTVYIDDVFVPDECVLGEVNRGWEVS
MUL_1194|M.ulcerans_Agy99 LDMKTEGVQVKPLRDLTGH--EMFNTVYIDDVFVPDECVLGEVNRGWEVS
MSMEG_0603|M.smegmatis_MC2_155 LDMKSPGVEVKPLRELTGN--AMFNTVFIDDVFVPDDMVLGEVNRGWEVS
MAB_4336|M.abscessus_ATCC_1997 VDMKSEGVTVRPLREMTGG--ALFNEVFIDDVFVPDELVVGEVNRGWEVS
Mflv_0441|M.gilvum_PYR-GCK IDMNADGVTVNPLRGLTGD--SHFNEVFFDDVFVPDADVVGDVNKGWLVA
Mvan_0226|M.vanbaalenii_PYR-1 IDMNAEGVTVNPLRGITGD--SHFNEVFFDDVFVPDADVVGDVNKGWLVA
MLBr_00737|M.leprae_Br4923 VHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTA
: . *. : * * . :::* : ::*: . *: :
MAV_2570|M.avium_104 MVTLGRERLTLGS-QAVSMFRLHERMVDAARD------HDLLDPVLSRSM
TH_4597|M.thermoresistible__bu IMTLGRERLTLGS-QAVAMFKLHEKLVAAARD------RGALDPVLARSM
Mb0277c|M.bovis_AF2122/97 RNTLTAERVSIGG-SDSTFLPTLGEFVDFVRDYR---FEGQFDQVARHRA
Rv0271c|M.tuberculosis_H37Rv RNTLTAERVSIGG-SDSTFLPTLGEFVDFVRDYR---FEGQFDQVARHRA
MMAR_0530|M.marinum_M RNTLTAERVSIGS-TDNNFLATLPQFVEFVRD-------GQFDQVAQHRA
MUL_1194|M.ulcerans_Agy99 RNTLTAERVSIGS-TDNNFLATLPQFVEFVRD-------GQFDQVAQHRA
MSMEG_0603|M.smegmatis_MC2_155 RNTLTNERVSIGS-SEPPFLANLDQFVQFLRD-------GQFDQIEQNHA
MAB_4336|M.abscessus_ATCC_1997 RNTLTAERVSIGS-SDLPFLASLDDLVAFVGT-------HDLGEVARDRA
Mflv_0441|M.gilvum_PYR-GCK RATLGNERVSIGGGSGGVTGTTPDHLIKLLDS------SPDRAPMFVRQA
Mvan_0226|M.vanbaalenii_PYR-1 RATLGNERISIGGGSGGPVGTTPDHLIKLLDS------SPATSAMYVRQA
MLBr_00737|M.leprae_Br4923 LATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFML
** * ::*. :
MAV_2570|M.avium_104 TRLWAR---MWLLRFTWQRAIDSGD-LTSPAFSVLKLMTSETDQDLGDMA
TH_4597|M.thermoresistible__bu TRLWAR---MWLLRYTWQRAIDEGD-TTSAAFSVLKLMTSETDRDLADMA
Mb0277c|M.bovis_AF2122/97 GQLIAEGHATKLLNLRSTLLTLAGG-DPMAPAAISKLLSMRTGQGYAEFA
Rv0271c|M.tuberculosis_H37Rv GQLIAEGHATKLLNLRSTLLTLAGG-DPMAPAAISKLLSMRTGQGYAEFA
MMAR_0530|M.marinum_M GHLIAEGHAAKVLNLRSTLLTLSGG-DAMPSAAISKLLSMRTGQGYAEFA
MUL_1194|M.ulcerans_Agy99 GHLIAEGHAAKVLNLRSTLLTLSGG-DAMPSAAISKLLSMRTGQGYAEFA
MSMEG_0603|M.smegmatis_MC2_155 GQLIAEGHAAKVLNLRSTLLTLAGG-DAMPNAAISKLLSMKTGQGYAEFA
MAB_4336|M.abscessus_ATCC_1997 GQLIAEGHGVKLLNLRSTLLTLAGG-DPMPSAAVSKLLGMRTGQGYAEFV
Mflv_0441|M.gilvum_PYR-GCK GEVIAEIHSLRLLNLRRATRAISGA-EPGPEGNVTKLVVAESGQHLTELA
Mvan_0226|M.vanbaalenii_PYR-1 GEVIAELHSLRLLNLRRATRAIAGA-EPGPEGNVTKLLVAESGQRLTELA
MLBr_00737|M.leprae_Br4923 ADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDA
: . :: * * . .
MAV_2570|M.avium_104 TEVLGTDACTDP----EEDGLVHHMLIGRAQTILGGTSEIQRNILGERVL
TH_4597|M.thermoresistible__bu TEVLGTDVCVDPTAGTDDADLVRAMLVGRAQTILGGTSEIQRNILGERVL
Mb0277c|M.bovis_AF2122/97 VSSFGTDAVIGDTE-RLPGKWGEYLLASRATTIYGGTSEVQLNIIAERLL
Rv0271c|M.tuberculosis_H37Rv VSSFGTDAVIGDTE-RLPGKWGEYLLASRATTIYGGTSEVQLNIIAERLL
MMAR_0530|M.marinum_M VSSFGTDAAIGDTD-ELAGKWGEYLLSSRATTIYGGTSEVQLNIIAERLL
MUL_1194|M.ulcerans_Agy99 VSSFGTDAAIGDTD-ELAGKWGEYLLSSRATTIYGGTSKVQLNIIAERLL
MSMEG_0603|M.smegmatis_MC2_155 VSTFGTDAAIGDPQ-EEPGRWAEYLLASRATTIYGGTTEVQLNIIAERLL
MAB_4336|M.abscessus_ATCC_1997 VNHFGQDGAIGDSE-QEQGRWADYLLASRATTIYGGTSEVQLNIIAERLL
Mflv_0441|M.gilvum_PYR-GCK FELAGTAAVVEQMP-QLTRSY----LGNRAMTIAGGTSEITRNTIAERIL
Mvan_0226|M.vanbaalenii_PYR-1 FELAGTAAVVGQTP-QLTRSY----LGNRAMTIAGGTSEITRNTIAERIL
MLBr_00737|M.leprae_Br4923 VQLFGGAGYTSDFP------VERFMRDAKITQIYEGTNQIQRVVMSRALL
. * : * **.:: :.. :*
MAV_2570|M.avium_104 GLPKEPR--
TH_4597|M.thermoresistible__bu GLPKEPR--
Mb0277c|M.bovis_AF2122/97 GLPRDP---
Rv0271c|M.tuberculosis_H37Rv GLPRDP---
MMAR_0530|M.marinum_M GLPRDP---
MUL_1194|M.ulcerans_Agy99 GLPRDP---
MSMEG_0603|M.smegmatis_MC2_155 GLPRDP---
MAB_4336|M.abscessus_ATCC_1997 GLPRDP---
Mflv_0441|M.gilvum_PYR-GCK GLPRDPLLR
Mvan_0226|M.vanbaalenii_PYR-1 GLPRDPLLR
MLBr_00737|M.leprae_Br4923 R--------