For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3071 | - | - | 100% (248) | - |
| M. thermoresistible (build 8) | TH_4501 | - | 1e-07 | 36.59% (82) | PUTATIVE conserved hypothetical regulatory protein |
| M. thermoresistible (build 8) | TH_4413 | - | 6e-06 | 40.00% (55) | PUTATIVE putative response regulator receiver protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3157c | devR | 2e-06 | 39.29% (56) | two component transcriptional regulatory protein DevR |
| M. gilvum PYR-GCK | Mflv_0277 | - | 1e-06 | 28.46% (130) | response regulator receiver protein |
| M. tuberculosis H37Rv | Rv3133c | devR | 2e-06 | 39.29% (56) | two component transcriptional regulatory protein DevR |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1522 | - | 8e-07 | 36.49% (74) | putative two-component system response regulator LuxR |
| M. marinum M | MMAR_2876 | - | 1e-06 | 35.37% (82) | putative regulatory protein |
| M. avium 104 | MAV_5280 | - | 6e-08 | 39.19% (74) | two-component system response regulator |
| M. smegmatis MC2 155 | MSMEG_0331 | - | 2e-07 | 37.65% (85) | transcriptional regulator, LuxR family protein |
| M. ulcerans Agy99 | MUL_2876 | - | 2e-07 | 36.59% (82) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_0348 | - | 3e-07 | 48.98% (49) | putative GAF sensor protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2876|M.marinum_M --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0331|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0348|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3157c|M.bovis_AF2122/97 --------------------------------------------------
Rv3133c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_5280|M.avium_104 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK MLPAAREAIAAVDADPRAATKSLVTGGIGTGKTTLLAAMRTTFRSAGRQV
TH_3071|M.thermoresistible__bu --------------------------------------------------
MMAR_2876|M.marinum_M --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0331|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0348|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3157c|M.bovis_AF2122/97 --------------------------------------------------
Rv3133c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_5280|M.avium_104 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK LSRPPDAGTPGDGAGYALVVDDAHLLGDDDLDRLTDLAGDPASTVVIATQ
TH_3071|M.thermoresistible__bu --------------------------------------------------
MMAR_2876|M.marinum_M --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0331|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0348|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3157c|M.bovis_AF2122/97 --------------------------------------------------
Rv3133c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_5280|M.avium_104 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK ALMHRSRLQVLMTVLARENPEVALRPLTAAQVQEAATSALGASVGPELTR
TH_3071|M.thermoresistible__bu --------------------------------------------------
MMAR_2876|M.marinum_M --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0331|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0348|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3157c|M.bovis_AF2122/97 --------------------------------------------------
Rv3133c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_5280|M.avium_104 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK LLVSVTGGFPFLVSAALSAIPDGAQSARQAAHFALIERLARLDGHLLDTL
TH_3071|M.thermoresistible__bu --------------------------------------------------
MMAR_2876|M.marinum_M --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0331|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0348|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3157c|M.bovis_AF2122/97 --------------------------------------------------
Rv3133c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_5280|M.avium_104 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK LVMTLSPGLGPDDVAAALRIPADEAVAAVDSARATALIDPAHTSQFLAAV
TH_3071|M.thermoresistible__bu --------------------------------------------------
MMAR_2876|M.marinum_M ----------------------------MIDAVDMPDPPAFPTLADDEHP
MUL_2876|M.ulcerans_Agy99 ------------MGFSPRRAIPERTVGGVIDVVDMPDPPAFPTLADDEHP
MSMEG_0331|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0348|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3157c|M.bovis_AF2122/97 --------------------------------------------------
Rv3133c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_5280|M.avium_104 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK HDGIAQIVGAARHHDVEMAVLDSQLALCTLTADLALRIADHGVRDDRLAT
TH_3071|M.thermoresistible__bu --------------------------------------------------
MMAR_2876|M.marinum_M GWASRPIRESDATRHYREAFGDCNVDPTDDPMAVVAEAIDVNAAAVRHAL
MUL_2876|M.ulcerans_Agy99 GWASRPIRESDATRHYREAFGDCNVDPTDDPMAVVAEAIDVNAAAVRHAL
MSMEG_0331|M.smegmatis_MC2_155 -----------------------------------MMTTKERPIGTELLS
Mvan_0348|M.vanbaalenii_PYR-1 -----------------------------------MVPGN----------
Mb3157c|M.bovis_AF2122/97 --------------------------------------------------
Rv3133c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_5280|M.avium_104 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK ALTDFAARVPDRPARAARLYRAATDAGTTAVRPALADALVLTGDCVTAGR
TH_3071|M.thermoresistible__bu --------------------------------------------------
MMAR_2876|M.marinum_M ESLGDVHAVNALETLLDLSSLEREMIEDGAARRTLALLQVQE--------
MUL_2876|M.ulcerans_Agy99 ESQGDVHAVNALETLLDLSSLEREMIEDGAARRTLALLQVQE--------
MSMEG_0331|M.smegmatis_MC2_155 RSSSAVATTLLSEKAFAAGRATHRDLASPGEQISAALDALLA--------
Mvan_0348|M.vanbaalenii_PYR-1 -----VGFAEMADRLADASAASQRMMTATAERAGRDLGGVLN--------
Mb3157c|M.bovis_AF2122/97 --------------------MVKVFLVDDHEVVRRGLVDLLG--------
Rv3133c|M.tuberculosis_H37Rv --------------------MVKVFLVDDHEVVRRGLVDLLG--------
MAB_1522|M.abscessus_ATCC_1997 --------------MTD--TEVGVLLVDDQELVRTGLRRILR--------
MAV_5280|M.avium_104 --------------MTDPAPEITVLLVDDQDLVRSGLRRILR--------
Mflv_0277|M.gilvum_PYR-GCK LADDLLTSQDPDERAAAVRIAASIALHDGAARQAADLFAWLGPAPDAVVG
TH_3071|M.thermoresistible__bu ----MTAEDYRCAFDIVSDCHDSSTLNEFREALVESLCRHLS--------
: *
MMAR_2876|M.marinum_M ---ALSKLRAVDDVAMIVDRAPRELVESCGFDRAVLFRVHEGRMVMESAY
MUL_2876|M.ulcerans_Agy99 ---ALSKLRAVDDVAMIVDRAPRELVESCGFDRAVLFRVHEGRLVMESAY
MSMEG_0331|M.smegmatis_MC2_155 ---SLDEVRQATSPAETLECAPRALATSAVFQRVMLSRVSGSTWLPDAVY
Mvan_0348|M.vanbaalenii_PYR-1 ---ALALLRENTAVPDVLQQAGLEVCRTAVFDWVMVSRVAGSTWRPVVRY
Mb3157c|M.bovis_AF2122/97 ---ADPELDVVGEAGSVAE-------------------------------
Rv3133c|M.tuberculosis_H37Rv ---ADPELDVVGEAGSVAE-------------------------------
MAB_1522|M.abscessus_ATCC_1997 ---RKDGFAIVGECADGSE-------------------------------
MAV_5280|M.avium_104 ---RKDGFVIVAECADGDE-------------------------------
Mflv_0277|M.gilvum_PYR-GCK AAETIAALAVGDAAAVRSTAQGPPSGPPTAVARSARAITEGLVMTLDQPY
TH_3071|M.thermoresistible__bu --IPNVSFFSGATFNQVFEDE-----------------------------
.
MMAR_2876|M.marinum_M FGEDREGAEKMVAFA----------------------QSVAPLLDHMLIE
MUL_2876|M.ulcerans_Agy99 FGEDREGAEKMVAFA----------------------QSVAPLLDHMLIE
MSMEG_0331|M.smegmatis_MC2_155 GVDGQRRRDVRFECYPD-----------------ERLEDLQIPLASPLVE
Mvan_0348|M.vanbaalenii_PYR-1 EMGADGRVTVDVDES-G-----------------CGVDTSDIPLMSPLVE
Mb3157c|M.bovis_AF2122/97 ------------------------------------------------AM
Rv3133c|M.tuberculosis_H37Rv ------------------------------------------------AM
MAB_1522|M.abscessus_ATCC_1997 ------------------------------------------------VA
MAV_5280|M.avium_104 ------------------------------------------------VP
Mflv_0277|M.gilvum_PYR-GCK PAAIARLSQAIAVDAVHGVLPDTPAALVTLAALHGGDPVRARSVIGRAVL
TH_3071|M.thermoresistible__bu ---------------------------------------------SPLTE
MMAR_2876|M.marinum_M TQMIRRHAPAIVRDARNDPRVNRPIVDFSLTHSYVAAPVMPTG---KVIG
MUL_2876|M.ulcerans_Agy99 TQMIRRHAPAIVRDARNDPRVNRPIVDFSLTHSYVAAPVMPTG---KMIG
MSMEG_0331|M.smegmatis_MC2_155 AEVVRRRLPALVSDAHHETRVHPPLIERMQAGEYVVAPITAGS---TVLG
Mvan_0348|M.vanbaalenii_PYR-1 AEVVRRRLPALVLDAGHEPRVHRPLVDRAGTTQYVVAPVVVEG---AVIG
Mb3157c|M.bovis_AF2122/97 ARVPAARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTS---YTSD
Rv3133c|M.tuberculosis_H37Rv ARVPAARPDVAVLDVRLPDGNGIELCRDLLSRMPDLRCLILTS---YTSD
MAB_1522|M.abscessus_ATCC_1997 AAVSRARPDVVIMDLRMKQMSGIEAIRLLHAAQ-GPPALALTT---FDDD
MAV_5280|M.avium_104 AAVAAHRPDVVVMDLRMRRVDGIEATRRLGGR---PPVLALTT---FNED
Mflv_0277|M.gilvum_PYR-GCK ADSRPDRADATFVTSRHRLLQGWAYMQDGQLAAAAAAIPADGDPRLHRRD
TH_3071|M.thermoresistible__bu GATRKMLPEYQDRWARHDVFGSPAAVRQLLASTVSSLNELKSQHRLPATA
MMAR_2876|M.marinum_M FLHADRLYSGRI--------------------------------------
MUL_2876|M.ulcerans_Agy99 FLHADRLYSGRI--------------------------------------
MSMEG_0331|M.smegmatis_MC2_155 LLHASRPTDGRP--------------------------------------
Mvan_0348|M.vanbaalenii_PYR-1 LIHASSAAPGRV--------------------------------------
Mb3157c|M.bovis_AF2122/97 EAMLDAILAG----------------------------------------
Rv3133c|M.tuberculosis_H37Rv EAMLDAILAG----------------------------------------
MAB_1522|M.abscessus_ATCC_1997 ELLSGALRAG----------------------------------------
MAV_5280|M.avium_104 ELLSGALRAG----------------------------------------
Mflv_0277|M.gilvum_PYR-GCK ALWAAALHTGIARRSGDTGAMQMHWRSAMDVLAESSADLFTVLPLGELWI
TH_3071|M.thermoresistible__bu VAYIRHFLHGR---------------------------------------
*
MMAR_2876|M.marinum_M --------------------------------------------------
MUL_2876|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_0331|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_0348|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb3157c|M.bovis_AF2122/97 --------------------------------------------------
Rv3133c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_1522|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_5280|M.avium_104 --------------------------------------------------
Mflv_0277|M.gilvum_PYR-GCK AASRLRQVDQVRHSLDEVFGLLAALGDPLLWSIPLHWAGVHAGILANSPD
TH_3071|M.thermoresistible__bu --------------------------------------------------
MMAR_2876|M.marinum_M ---------------------VDEIDRDTVWAFAEGFGYAYERTVLLERM
MUL_2876|M.ulcerans_Agy99 ---------------------VDEIDRDTVWAFAEGFGYAYERTVLLERM
MSMEG_0331|M.smegmatis_MC2_155 ---------------------LTTAHRDLLRMFADGVGLSYEHALLVERI
Mvan_0348|M.vanbaalenii_PYR-1 ---------------------LTDLDRDLLRMFADGVGLVYERAALAERS
Mb3157c|M.bovis_AF2122/97 ---------------------------------ASGYVVKDIKGMELARA
Rv3133c|M.tuberculosis_H37Rv ---------------------------------ASGYVVKDIKGMELARA
MAB_1522|M.abscessus_ATCC_1997 ---------------------------------AAGFILKDSPAEELVRA
MAV_5280|M.avium_104 ---------------------------------AAGFVLKDSSAEELIRA
Mflv_0277|M.gilvum_PYR-GCK AVAPHGAALTAAAPHAQFAKALAAAGRTWLRVLADRVDVAEVTAAARGLA
TH_3071|M.thermoresistible__bu --------------------------------WDMGSAAAMQLPLSRGRT
MMAR_2876|M.marinum_M RRQHAEVRSALASADEAARALQDADLDLRKIEPVERSPAARSLAEVQT--
MUL_2876|M.ulcerans_Agy99 RRQHAEVRSALASADEAARALQDADLDLRKIEPVERSPAARSLAEVQT--
MSMEG_0331|M.smegmatis_MC2_155 ERQRRYVLDACDSAVRSAAGTDLTTPIPLRPRP-FRTNTVVSTQTSFTQT
Mvan_0348|M.vanbaalenii_PYR-1 ERQRCAVTEVCDAAVRSFDEVNPIAAFGLGSEPGLVSPDGDSVPAPFAGI
Mb3157c|M.bovis_AF2122/97 VKDVGAGRSLLDNRAAAALMAKLRGAAE----------------------
Rv3133c|M.tuberculosis_H37Rv VKDVGAGRSLLDNRAAAALMAKLRGAAE----------------------
MAB_1522|M.abscessus_ATCC_1997 VHAVARGEAYLDPAVTSRVLNAYRRAPAA---------------------
MAV_5280|M.avium_104 VRAVARGEGYLDPAVTSRVLTTYRKAAPG---------------------
Mflv_0277|M.gilvum_PYR-GCK LHGHTWDATRLAGQAALQTTDSRAAQAMLQLARDLKATVAASDASVPSSA
TH_3071|M.thermoresistible__bu ALVGFFSPHPEDLGPRELAILRLVGNQLSPVSRRLPAEP-----------
MMAR_2876|M.marinum_M -------------RAMAMLTRREVEVLRLMAAGRTNQQIADELVISAGTV
MUL_2876|M.ulcerans_Agy99 -------------RVMAMLTRREVEVLRLMAAGRTNQQIADELVISAGTV
MSMEG_0331|M.smegmatis_MC2_155 SQRRES-------SRLTILTSREREVLALLASGATNAQLADQLTVAESTV
Mvan_0348|M.vanbaalenii_PYR-1 CESRGAG---RGGTRLARLTAREREVLALLASGATNAQLADRLTVAESTV
Mb3157c|M.bovis_AF2122/97 -----------KQDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTV
Rv3133c|M.tuberculosis_H37Rv -----------KQDPLSGLTDQERTLLGLLSEGLTNKQIADRMFLAEKTV
MAB_1522|M.abscessus_ATCC_1997 ----------VSGDAQDKLTARELDVLALIASGATNSEIAEQLVISEVTV
MAV_5280|M.avium_104 ----------PHGAAIAELTTRERDVLTLIGKGLSNSEIADELCISGVTV
Mflv_0277|M.gilvum_PYR-GCK TDTVAPPPAVPQRVSSTQLSEREREVAELLLQGLPYREIGSQLFISAKTV
TH_3071|M.thermoresistible__bu -----------ALRVINRLTERQRDVAKLVADGLSNAEIADILCLAEDTV
*: :: : *: * . ::.. : :: **
MMAR_2876|M.marinum_M KSHVKRVLRKLHATNRAEAASAYVRLASVPEVG---
MUL_2876|M.ulcerans_Agy99 KSHVKRVLRKLHATNRAEAASAYVRLASVSEVG---
MSMEG_0331|M.smegmatis_MC2_155 KSHVKHILHKLGASNRAAAISFYLRETRGRSRS---
Mvan_0348|M.vanbaalenii_PYR-1 KSHVKHILHKLGAGNRAAAIACYLRESPDRERQRR-
Mb3157c|M.bovis_AF2122/97 KNYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP
Rv3133c|M.tuberculosis_H37Rv KNYVSRLLAKLGMERRTQAAVFATELKRSRPPGDGP
MAB_1522|M.abscessus_ATCC_1997 KSHIGRIFVKLDLRDRAAAIVYAYDHGIVTPK----
MAV_5280|M.avium_104 KSHIGRIFGKLDLRDRAAAIVYAYDNGIVAPR----
Mflv_0277|M.gilvum_PYR-GCK EHHVARIRRRLGAESRSEMLSMLRAALDTPASR---
TH_3071|M.thermoresistible__bu KKYVTRILHQTACRSRLELALIIRDAGL--------
: :: :: : *