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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2995 | - | - | 100% (491) | AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_4193 | - | e-147 | 73.74% (358) | PUTATIVE AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_4415 | - | e-140 | 52.88% (486) | PUTATIVE AMP-dependent synthetase and ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0276 | fadD2 | 1e-51 | 31.39% (497) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_2385 | - | 0.0 | 74.13% (491) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv0270 | fadD2 | 1e-51 | 31.39% (497) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 1e-53 | 31.09% (505) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_2539c | - | 2e-50 | 31.27% (502) | fatty-acid-CoA ligase FadD |
| M. marinum M | MMAR_0466 | - | 0.0 | 71.28% (484) | long-chain-fatty-acid-CoA ligase |
| M. avium 104 | MAV_2574 | - | 0.0 | 73.40% (485) | feruloyl-CoA synthetase |
| M. smegmatis MC2 155 | MSMEG_4883 | - | 0.0 | 77.11% (485) | AMP-dependent synthetase and ligase |
| M. ulcerans Agy99 | MUL_1115 | - | 0.0 | 70.45% (484) | long-chain-fatty-acid-CoA ligase |
| M. vanbaalenii PYR-1 | Mvan_4263 | - | 0.0 | 72.91% (491) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2385|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4263|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4883|M.smegmatis_MC2_155 --------------------------------------------------
TH_2995|M.thermoresistible__bu --------------------------------------------------
MMAR_0466|M.marinum_M --------------------------------------------------
MUL_1115|M.ulcerans_Agy99 --------------------------------------------------
MAV_2574|M.avium_104 --------------------------------------------------
Mb0276|M.bovis_AF2122/97 MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNY
Rv0270|M.tuberculosis_H37Rv MPNLTDLPGQAVSKLQKSIGQYVARGTAELHYLRKIIESGAIGLEPPLNY
MLBr_02546|M.leprae_Br4923 -----------MTKLR----HYLERGAAEVHYLRSIFESGALGFEPPLTY
MAB_2539c|M.abscessus_ATCC_199 MP----------NNLR----ESLRQWGAAIP---AAVTSGAFTPVSPRAL
Mflv_2385|M.gilvum_PYR-GCK -----------MSISLLLEMATDAGPDRTAVVSDDTRLTTAELSALADGG
Mvan_4263|M.vanbaalenii_PYR-1 -----------MSISLLLEMAQDAGPDRTAVVSDDLRLTTAELSALADGG
MSMEG_4883|M.smegmatis_MC2_155 -----------MSISLLLEMASSGDPDRTAVVSDDTRLTAGELSTLADGA
TH_2995|M.thermoresistible__bu -------------------MAVSGDPDRVAVIDRDVRLTTTELARLAGGG
MMAR_0466|M.marinum_M -----------MSVSLLLEMAASASPDRIAVVSGDLRLTTQQLSDLADGG
MUL_1115|M.ulcerans_Agy99 -----------MSVSLLLEMAASASPDRIAVVSGDLRLKTQQLSDLADGG
MAV_2574|M.avium_104 ---------------MLLEMAASGDPDRVAVVDGDIRLTTVDLSELADGG
Mb0276|M.bovis_AF2122/97 AALAADIRKWG-EVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAV
Rv0270|M.tuberculosis_H37Rv AALAADIRKWG-EVGMLPSHNARRAPNRAAVIDEEGTLTFSELDEAAHAV
MLBr_02546|M.leprae_Br4923 AAMAVAMRKWG-DLAMLPAMPARRSPHRAALIDEEGTLTYKELDRAAHAL
MAB_2539c|M.abscessus_ATCC_199 ASLVRSFWQFGPTPAMLLAASAIRFPDRAALIDDSGQLTYRDLQRRAEAV
*.* *::. . *. :* * .
Mflv_2385|M.gilvum_PYR-GCK AGVIAAS---GARHVAYVGTGGALLPLLLFASARAAVPVTPLNYRLSAEG
Mvan_4263|M.vanbaalenii_PYR-1 AGVIAAS---GARHVAYVGAGGAMLPLLLFASARAAVPVTPLNYRLSADG
MSMEG_4883|M.smegmatis_MC2_155 AGVIAGS---GAAHVAYVGTGGALLPLLLFASARAAIPFTPLNYRLSAEG
TH_2995|M.thermoresistible__bu AQVIAGS---GVQHVAYVGLGGAMLPLLIFASTHATVPFTPLNYRLSAEG
MMAR_0466|M.marinum_M AGAIAAS---DAQHVVYVGTGGAMLPLLIFASARAGLPFTSINYRLSADG
MUL_1115|M.ulcerans_Agy99 AGAIAAS---DAQHVVYVGTGGAMLPLLIFASARAGLPFTSINYRLSADG
MAV_2574|M.avium_104 AGVIAAS---GASHVAYVGTGGVLLPLLLFSSARANTAFTPLNYRLSPEG
Mb0276|M.bovis_AF2122/97 ANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQ
Rv0270|M.tuberculosis_H37Rv ANGLLAKGVRAGDGVAILARNHRWFVIANYGAARVGARIILLNSEFSGPQ
MLBr_02546|M.leprae_Br4923 ANGLIAKGVRGGDGIAILARNHRWFVIANYGCARVGARIILLNSEFSGPQ
MAB_2539c|M.abscessus_ATCC_199 AAAVYARTPSAPRSVGIICRNHRGFAESMLAGAQLGAELVFINTELTPQQ
* : . : : . : . :: . :* .::
Mflv_2385|M.gilvum_PYR-GCK LRALLDRLPDPLVVVDDEYRDAVGDSYR-TMGSREFFEASRTAEP-----
Mvan_4263|M.vanbaalenii_PYR-1 LRALLDRLPDPLVVVDDEYRDAVGDGYR-TIGSAEFLDAARTAEP-----
MSMEG_4883|M.smegmatis_MC2_155 LRELVDRLPTPLVIADGEYAGMLAGAGRPVLTSEEFLSQARTADP-----
TH_2995|M.thermoresistible__bu LHQLIERLPSPLVIADDEYVDAVAGTGKQVMRSSEFVEAARAAEP-----
MMAR_0466|M.marinum_M IAALIRRLPRPLVVVDERYRDTIA--ADQSLSSQQFLELAGRAEP-----
MUL_1115|M.ulcerans_Agy99 IAALIRRLPRPLVVVDERYRETIA--ADQSLSSQQFLELAGRAEP-----
MAV_2574|M.avium_104 LRELIDRLPSPLVVVDAEYRDIGAGFGQRVMTSDEFIEAARSTEP-----
Mb0276|M.bovis_AF2122/97 IKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSD
Rv0270|M.tuberculosis_H37Rv IKEVSDREGAKVIIYDDEYTKAVSLAQPPLGKLRALGVNPDDDKPSGSSD
MLBr_02546|M.leprae_Br4923 IKEVSEREGAKVIIYDDEYTKVVSKAEPALGKLRALGVNPDEEEPPGSTD
MAB_2539c|M.abscessus_ATCC_199 LGAILQRHEPDVLVYDDEYSQAVEESQYQGLRVLAWRENPQENR------
: : * ::: * .* .
Mflv_2385|M.gilvum_PYR-GCK --AAEFADPDS----------VGVVLFTSGTTSKPKAVELTH--TNLTSY
Mvan_4263|M.vanbaalenii_PYR-1 --AAEFADPDA----------VGVVLFTSGTTSKPKAVELSH--ANLTSY
MSMEG_4883|M.smegmatis_MC2_155 --AAEFADPDA----------VAVVLFTSGTTSRPKAVELTH--NNLTSY
TH_2995|M.thermoresistible__bu --LEGFADPDS----------VGIVLFTSGTTSRPKAVELTH--NNLTSY
MMAR_0466|M.marinum_M --VAEFPDPDS----------VAIVLFTSGTTSQPKAVELTH--SNLTSY
MUL_1115|M.ulcerans_Agy99 --VAEFPDPDS----------VAIVLFTSGTTSQPKAVELTH--SNLTSY
MAV_2574|M.avium_104 --VSVFADPDD----------VAVVLFTSGTTSRPKAVELTH--NNLTSY
Mb0276|M.bovis_AF2122/97 ETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNT-PPTLAPI
Rv0270|M.tuberculosis_H37Rv ETLAELIAHSSTAPAPKASRRASIIILTSGTTGTPKGANRNT-PPTLAPI
MLBr_02546|M.leprae_Br4923 ETLAELIARSSSAPAPKVRKRASIIILTSGTTGTPKGANRNT-PASLAPL
MAB_2539c|M.abscessus_ATCC_199 LTLDSLADQHHPKPPP-VRRPVKLTLLTSGTTGLAKGVPRAIKPRQLALM
: . : ::*****. .*.. *:
Mflv_2385|M.gilvum_PYR-GCK IMGTVEFASAEPDDAALICVPPYHIAGVSAALSNLYAGRKMVYLRHFDAE
Mvan_4263|M.vanbaalenii_PYR-1 IMGTVEFASAEPDDAALICVPPYHIAGVSAALSNLYAGRKMVYLTQFDAG
MSMEG_4883|M.smegmatis_MC2_155 ITGTVEFGSAAPEDAALICVPPYHIAGVSAAMSNLYAGRKMVYLRNFDAH
TH_2995|M.thermoresistible__bu VTGTVEFADADAEDAALVCVPPYHIAGVGAALSNLYAGRKIVCLSRFDPA
MMAR_0466|M.marinum_M VTTTVEFGCAAPSDAALICVPPYHIAGVSAVLSNLYAGRKMVYLTNFDAH
MUL_1115|M.ulcerans_Agy99 VTTTVEFGCAAPSDAALICVPPYHIAGVSAVLSNLYAGRKMVYLNNFDAH
MAV_2574|M.avium_104 VTGTVEFGSADPADAALVCVPPYHIAGVGAALSNLYAGRAIVYLRRFDPH
Mb0276|M.bovis_AF2122/97 GG-ILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPA
Rv0270|M.tuberculosis_H37Rv GG-ILSHVPFKAGEVTLLPSPMFHALGYMHAALAMFLGSTLVLRRRFKPA
MLBr_02546|M.leprae_Br4923 GG-ILSKVPFRAHEVTLLPAPMFHALGYLHATLAMFLGSTLVLRRRFKPA
MAB_2539c|M.abscessus_ATCC_199 CVTAMATVRLRSRDRVLVAPPFFHGFGLAALLGPLALGGTVMCRRRFDAQ
: . : .*: * :* * : * :: .*..
Mflv_2385|M.gilvum_PYR-GCK KWVRLVADEGVTSATVVPTMLDRIVTVLET--TDTALPTLRTLAYGGSKV
Mvan_4263|M.vanbaalenii_PYR-1 RWVDLVTGEGVTSATVVPTMLDRIVSVLET--RGTTLPTLRTLAYGGSKV
MSMEG_4883|M.smegmatis_MC2_155 RWVELVRTEGVTSATVVPTMLDRIVTALET--TRAELPTLRNLAYGGSKV
TH_2995|M.thermoresistible__bu EWVRLVADEKVTTATVVPTMLDRIVTELEA--RPRELPSLRNLAYGGSKV
MMAR_0466|M.marinum_M EWVRLTNAEQVTTATVVPTMLDRIVAVLET--GEHKLPSLRNLAYGGSKV
MUL_1115|M.ulcerans_Agy99 EWVRLTNAEQVTTATVVPTMLDRIVAVLET--GEHKLPSLRNLAYGCSKV
MAV_2574|M.avium_104 EWVRLVRDERVTTATVVPTMLSRIVAVLEE--QSAELPTLRNFAYGGSKV
Mb0276|M.bovis_AF2122/97 LVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQL
Rv0270|M.tuberculosis_H37Rv LVLEDIEKHKATSMVVVPVMLSRILDQLEKTEPKPDLSSLKIVFVSGSQL
MLBr_02546|M.leprae_Br4923 TVLEDIEKHQATAMVVVPVMLSRILDTLENLETKSDLSSLRVVFVSGSQL
MAB_2539c|M.abscessus_ATCC_199 QAMTDIRRQRVTVLMAVPVMLQRILALADLDRRDARQLSLRMIVTGAAPI
: . .* .**.**.**: : :*: . . : :
Mflv_2385|M.gilvum_PYR-GCK PLPLVRKALSLLPDVGFVNAYGLTETSSTIAVLTPDDHRAALAAADDAAL
Mvan_4263|M.vanbaalenii_PYR-1 PLPLVRKALSLLPAVGFVNAYGLTETSSTIAVLTPDDHRAALAASDEAAI
MSMEG_4883|M.smegmatis_MC2_155 ALPLVRKALELMPNVGFVNAYGLTETSSTIAVLGPDDHRAALASDDPGVT
TH_2995|M.thermoresistible__bu GLPLVRKALELLPDVGFVNAYGLTETSSTIAVLGPEDHRIALASDDEKVV
MMAR_0466|M.marinum_M GLPLVRRALELLPDVGFVNAYGLTETSSTIAVLTPDDHRAAQSAAAAGLA
MUL_1115|M.ulcerans_Agy99 GLPLVRRALELLPDVGFVNAYRLTETSSTIAVLTPDDHRAAQSAAAAGLA
MAV_2574|M.avium_104 ARPLVRRALDLLPQVGFVNAYGLTETSSTIAVLTPEDHRLAHEARDDAVA
Mb0276|M.bovis_AF2122/97 GAELATRALGDLGPV-IYNMYGSTEVAFATIAGPKD------------LQ
Rv0270|M.tuberculosis_H37Rv GAELATRALGDLGPV-IYNMYGSTEVAFATIAGPKD------------LQ
MLBr_02546|M.leprae_Br4923 GAELATRALEELGPV-IYNMYGSTEIAFATIAGPKD------------LQ
MAB_2539c|M.abscessus_ATCC_199 SSSTVSGVLEAFGPI-LVNGYGSTEAGVVAIASPKD------------LV
. .* : : : * * ** . . . :
Mflv_2385|M.gilvum_PYR-GCK RRLGSVGQPVPGIEVEVRAEDGTVLGPGETGELFVRGEQVSGKYTDIGS-
Mvan_4263|M.vanbaalenii_PYR-1 RRLGSVGQPVPGIEVEIRADDGTVLGAGETGELFVRGEQVSGKYTDIGS-
MSMEG_4883|M.smegmatis_MC2_155 RRLGSVGQVVPGIEVQIRGEDGTVLGPGETGELFVRGEQVSGRYTEIGS-
TH_2995|M.thermoresistible__bu RRLGSVGQPVPGIEIQIRSKNGEVLGPGETGELFVRGPQVSGRYTGIGS-
MMAR_0466|M.marinum_M RRLGSVGRPVPGVELQIRGQDGRVLGPGETGELFVRGGQVSGRYTGIGS-
MUL_1115|M.ulcerans_Agy99 RRLGSVGRPVPGVELQIRGQDGRVLGPGETGELFVRGEQVSGRYTGIGS-
MAV_2574|M.avium_104 RRLTSVGRPVPGIEVQIRAEDGTVLGPGETGELFVRGPQVSGRYTEIGS-
Mb0276|M.bovis_AF2122/97 FNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGG-
Rv0270|M.tuberculosis_H37Rv FNPSTVGPVVKGVTVKILDENGNEVPQGAVGRIFVGNAFPFEGYTGGGG-
MLBr_02546|M.leprae_Br4923 INSATVGPVVKGVKVKILDDSGKEVPRGQVGRIFVGNAFPFEGYTGGGG-
MAB_2539c|M.abscessus_ATCC_199 ASPNTIGRTALGVSVRILREDRRPAAPGETGMIFVRGGLEYEGYTPDKAT
::* . *: :.: .. * .* :** . ** .
Mflv_2385|M.gilvum_PYR-GCK ----VLDENGWFPTKDVAYLDSEGYLFIGGRSDDTIIRGGENIAPAEIED
Mvan_4263|M.vanbaalenii_PYR-1 ----VLDEQGWFPTKDVAFLDEEGYLFIGGRSDDTIIRGGENIAPAEIED
MSMEG_4883|M.smegmatis_MC2_155 ----VLDEDGWFPTKDVAMLDQDGYLFIGGRSDDTIIRGGENIAPAEIED
TH_2995|M.thermoresistible__bu ----VLDDDGWFPTKDVAMVDEDGYLFIGGRSDDTIIRGGENIAPAEIEN
MMAR_0466|M.marinum_M ----VLDGHGWFGTKDIAMLDEDGYLFIGGRSDDTIIRGGENIAPAELEE
MUL_1115|M.ulcerans_Agy99 ----VLDGHGWFGTKDIAMLDEDGYLFIGGRSDDTIIRGGENIAPAELEE
MAV_2574|M.avium_104 ----VLDDHGWFATRDVAMLDEDGYLFIGGRSDDTIIRGGENIAPSEVED
Mb0276|M.bovis_AF2122/97 ----KQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVED
Rv0270|M.tuberculosis_H37Rv ----KQIIDGLLSSGDVGYFDERGLLYVSGRDDEMIVSGGENVFPAEVED
MLBr_02546|M.leprae_Br4923 ----KQIIDGLLSSGDVGYFDEHDLLYISGRDDEMIVSGGENVFPAEVED
MAB_2539c|M.abscessus_ATCC_199 RPTAKEIVDGHVNTGDMGHFDADGRLYIDGRSDDMIVSGGENVFPGEVED
.* . : *:. .* . *::.**.*: *: ****: *.*:*:
Mflv_2385|M.gilvum_PYR-GCK VLVEHPHVRDCAVVGADDPQWGQIIVAVVVPHQDTAPD-PEDLRAHVRSQ
Mvan_4263|M.vanbaalenii_PYR-1 VLVEHPHVRDCAVVGADDPEWGQIIVAVVVAQPGTEPD-VEDLRSHVRSQ
MSMEG_4883|M.smegmatis_MC2_155 VLVEHPDVRDVAVVGPEDPQWGQIIVAVVVPADGAEPD-ADVLREHVRKH
TH_2995|M.thermoresistible__bu VLVEHPQVREAVVVGPEDPQWGQILVAVVVPAEGETPD-PEELRAHVRKH
MMAR_0466|M.marinum_M VLIEHPQVRDVAVVGVEDAQWGQEIVAVVVPVAGVDPD-PEELREFVRRS
MUL_1115|M.ulcerans_Agy99 VLIEHPQVRDVAVVGVEDAQWGQEIVAVVVPVAGVDPD-PEELREFVRRS
MAV_2574|M.avium_104 VLIEHPDVREVVVVGLDDAEWGQAIVAVIVPESGTAPA-PERLREFARSK
Mb0276|M.bovis_AF2122/97 LISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLD-EDTIKQYVRDH
Rv0270|M.tuberculosis_H37Rv LISGHPDVVEAAAIGVDDKEFGARLRAFVVKKPGADLD-EDTIKQYVRDH
MLBr_02546|M.leprae_Br4923 LISGHPEVVEATAIGVDDKEWGARLRAFVVKKQDATID-EDAIKAYVRDH
MAB_2539c|M.abscessus_ATCC_199 RLTTYPGITDAVVIGVPDDDFGQVLHAFVVAADGAPAPSEEVLKTHVRQG
: :* : : ..:* * ::* : *.:* . : :: ..*
Mflv_2385|M.gilvum_PYR-GCK LRGSRTPDRVVFRDELPTNATGKVLRRELVSELNQDRSPAQPAV
Mvan_4263|M.vanbaalenii_PYR-1 LRGSRTPDRVVFRDELPTNATGKVLRRELVDELNQDPSPAQPAV
MSMEG_4883|M.smegmatis_MC2_155 LRGSRTPDRVVFRAELPTNATGKVLRRQLVDEL-------QPIS
TH_2995|M.thermoresistible__bu LRGSRTPDKVVFRTELPVNALGKVLRRQLVDELQT----KEPA-
MMAR_0466|M.marinum_M LRGSRTPDRVVFRHELPTTATGKILRREIIEELAG----TKS--
MUL_1115|M.ulcerans_Agy99 LRGSRTPDRVVFRRELPTTATGKILRREIIEELAG----TKS--
MAV_2574|M.avium_104 LRGSRTPDRIVFRDELPTTPTGKVLRREILEDLKP----AAAEH
Mb0276|M.bovis_AF2122/97 LARYKVPREVIFLDELPRNPTGKVLKRELRKL------------
Rv0270|M.tuberculosis_H37Rv LARYKVPREVIFLDELPRNPTGKVLKRELRKL------------
MLBr_02546|M.leprae_Br4923 LARYKVPREVIFLEELPRNPTGKVLKRELRDFEVH---------
MAB_2539c|M.abscessus_ATCC_199 LERYKVPKRFIVLDEIPRNASGKVLRAKLNSPGAC---------
* :.* ..:. *:* .. **:*: :: .