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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4415 | - | - | 100% (500) | AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_2995 | - | e-140 | 52.88% (486) | PUTATIVE AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_3448 | - | e-130 | 49.20% (500) | PUTATIVE putative AMP-dependent synthetase and ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3116 | fadD13 | 1e-48 | 28.37% (490) | chain-fatty-acid-CoA ligase |
| M. gilvum PYR-GCK | Mflv_2385 | - | 1e-140 | 52.22% (496) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv3089 | fadD13 | 1e-48 | 28.37% (490) | chain-fatty-acid-CoA ligase |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 8e-43 | 28.43% (503) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4559 | - | 3e-55 | 30.99% (497) | putative long-chain-fatty-acid CoA ligase |
| M. marinum M | MMAR_0466 | - | 1e-145 | 54.45% (494) | long-chain-fatty-acid-CoA ligase |
| M. avium 104 | MAV_4950 | - | 1e-148 | 54.00% (500) | AMP-dependent synthetase and ligase |
| M. smegmatis MC2 155 | MSMEG_4883 | - | 1e-147 | 54.45% (494) | AMP-dependent synthetase and ligase |
| M. ulcerans Agy99 | MUL_1115 | - | 1e-143 | 53.85% (494) | long-chain-fatty-acid-CoA ligase |
| M. vanbaalenii PYR-1 | Mvan_4263 | - | 1e-139 | 52.62% (496) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3116|M.bovis_AF2122/97 ---------------------------------------------MKNIG
Rv3089|M.tuberculosis_H37Rv ---------------------------------------------MKNIG
MAB_4559|M.abscessus_ATCC_1997 ---------------------------------------------MQFTQ
MMAR_0466|M.marinum_M ---------------------------------------------MSVSL
MUL_1115|M.ulcerans_Agy99 ---------------------------------------------MSVSL
MAV_4950|M.avium_104 ---------------------------------------------MSISL
Mflv_2385|M.gilvum_PYR-GCK ---------------------------------------------MSISL
Mvan_4263|M.vanbaalenii_PYR-1 ---------------------------------------------MSISL
MSMEG_4883|M.smegmatis_MC2_155 ---------------------------------------------MSISL
TH_4415|M.thermoresistible__bu ---------------------------------------------MGIEI
MLBr_02546|M.leprae_Br4923 MTKLRHYLERGAAEVHYLRSIFESGALGFEPPLTYAAMAVAMRKWGDLAM
Mb3116|M.bovis_AF2122/97 WMLRQRATVSPRLQAYVEPSTDVRMTYAQMNALANRCADVLTALGIAKGD
Rv3089|M.tuberculosis_H37Rv WMLRQRATVSPRLQAYVEPSTDVRMTYAQMNALANRCADVLTALGIAKGD
MAB_4559|M.abscessus_ATCC_1997 WLHRALQQYPDRLITIDQ---GREHTVEQFADRVARLSAGLRANGVRPGD
MMAR_0466|M.marinum_M LLEMAASASPDRIAVVSG---DLRLTTQQLSDLADGGAGAIAASDAQ---
MUL_1115|M.ulcerans_Agy99 LLEMAASASPDRIAVVSG---DLRLKTQQLSDLADGGAGAIAASDAQ---
MAV_4950|M.avium_104 LLEMAASSNAERTAVVSQ---DVRLTTQELSDLADGGAAVVAGSNAK---
Mflv_2385|M.gilvum_PYR-GCK LLEMATDAGPDRTAVVSD---DTRLTTAELSALADGGAGVIAASGAR---
Mvan_4263|M.vanbaalenii_PYR-1 LLEMAQDAGPDRTAVVSD---DLRLTTAELSALADGGAGVIAASGAR---
MSMEG_4883|M.smegmatis_MC2_155 LLEMASSGDPDRTAVVSD---DTRLTAGELSTLADGAAGVIAGSGAA---
TH_4415|M.thermoresistible__bu VLDMAVSAMADRVAVGRR---DSGLTYRQLDDMAAGGAGLLRDRGVE---
MLBr_02546|M.leprae_Br4923 LPAMPARRSPHRAALIDE---EGTLTYKELDRAAHALANGLIAKGVRGGD
. * . :: . : : .
Mb3116|M.bovis_AF2122/97 RVALLMPNSVEFCCLFYGAAKLGAVAVPINTRLAAPEVSFILSDSGSKVV
Rv3089|M.tuberculosis_H37Rv RVALLMPNSVEFCCLFYGAAKLGAVAVPINTRLAAPEVSFILSDSGSKVV
MAB_4559|M.abscessus_ATCC_1997 RVGMLSLNSDRYIEYLTAVPWLGAALNAVNIRWSLAEIGYSLRESGTRVL
MMAR_0466|M.marinum_M HVVYVGTGGAMLPLLIFASARAGLPFTSINYRLSADGIAALIRRLPRPLV
MUL_1115|M.ulcerans_Agy99 HVVYVGTGGAMLPLLIFASARAGLPFTSINYRLSADGIAALIRRLPRPLV
MAV_4950|M.avium_104 HLVYVGTGGVLLPVLIFTAARAGVAFTPINYRLSAEGIRALIERLPEPLV
Mflv_2385|M.gilvum_PYR-GCK HVAYVGTGGALLPLLLFASARAAVPVTPLNYRLSAEGLRALLDRLPDPLV
Mvan_4263|M.vanbaalenii_PYR-1 HVAYVGAGGAMLPLLLFASARAAVPVTPLNYRLSADGLRALLDRLPDPLV
MSMEG_4883|M.smegmatis_MC2_155 HVAYVGTGGALLPLLLFASARAAIPFTPLNYRLSAEGLRELVDRLPTPLV
TH_4415|M.thermoresistible__bu HLVFVGVNGPIIPVLMFAAAKAGIPLAPMNYRLPSDQMRALIAQLDRPMI
MLBr_02546|M.leprae_Br4923 GIAILARNHRWFVIANYGCARVGARIILLNSEFSGPQIKEVSEREGAKVI
: : . . . :* . . : ::
Mb3116|M.bovis_AF2122/97 IYGAPSAPVIDAIRAQADPPGTVTDWIGADS-----LAERLRSAA-ADEP
Rv3089|M.tuberculosis_H37Rv IYGAPSAPVIDAIRAQADPPGTVTDWIGADS-----LAERLRSAA-ADEP
MAB_4559|M.abscessus_ATCC_1997 LVDDTFKAAAAPLRAACACLETVIYCGAGPAPQDMIGYEDLLASH-EPID
MMAR_0466|M.marinum_M VVDERYRDTIAADQS--LSSQQFLELAGRAEPVA----------------
MUL_1115|M.ulcerans_Agy99 VVDERYRETIAADQS--LSSQQFLELAGRAEPVA----------------
MAV_4950|M.avium_104 VVDARYRDMVGEAPGGVMDSDDFLAAARAAEPAAD---------------
Mflv_2385|M.gilvum_PYR-GCK VVDDEYRDAVGDSYR-TMGSREFFEASRTAEPAA----------------
Mvan_4263|M.vanbaalenii_PYR-1 VVDDEYRDAVGDGYR-TIGSAEFLDAARTAEPAA----------------
MSMEG_4883|M.smegmatis_MC2_155 IADGEYAGMLAGAGRPVLTSEEFLSQARTADPAA----------------
TH_4415|M.thermoresistible__bu VTDSAYRADLEGASEHVLTSDEFVATARGAGRVDH---------------
MLBr_02546|M.leprae_Br4923 IYDDEYTKVVSKAEPALGKLRALGVNPDEEEPPGSTDETLAELIARSSSA
: . .
Mb3116|M.bovis_AF2122/97 AVECGGDDNLFIMYTSGTTGHPKGVVHTHESVHSAASSWASTIDVRYR-D
Rv3089|M.tuberculosis_H37Rv AVECGGDDNLFIMYTSGTTGHPKGVVHTHESVHSAASSWASTIDVRYR-D
MAB_4559|M.abscessus_ATCC_1997 DTRTGGDSLLGVFYTGGTTGNPKGVMLSHNNVLASAMGSLSTGNFLTRGG
MMAR_0466|M.marinum_M -EFPDPDSVAIVLFTSGTTSQPKAVELTHSNLTSYVTTTVEFGCAAPS-D
MUL_1115|M.ulcerans_Agy99 -EFPDPDSVAIVLFTSGTTSQPKAVELTHSNLTSYVTTTVEFGCAAPS-D
MAV_4950|M.avium_104 -AFADPDSVAIVLFTSGTTSQPKAVELSHNNLTSYITGTVEFGAADET-D
Mflv_2385|M.gilvum_PYR-GCK -EFADPDSVGVVLFTSGTTSKPKAVELTHTNLTSYIMGTVEFASAEPD-D
Mvan_4263|M.vanbaalenii_PYR-1 -EFADPDAVGVVLFTSGTTSKPKAVELSHANLTSYIMGTVEFASAEPD-D
MSMEG_4883|M.smegmatis_MC2_155 -EFADPDAVAVVLFTSGTTSRPKAVELTHNNLTSYITGTVEFGSAAPE-D
TH_4415|M.thermoresistible__bu -PPAPDDGTAIVLFTSGTTSAPKGVLLRHHQLSAYLFNTVEFGAAGDE-E
MLBr_02546|M.leprae_Br4923 PAPKVRKRASIIILTSGTTGTPKGANRNTPASLAPLGGILSKVPFRAH-E
. :: *.***. **.. : .
Mb3116|M.bovis_AF2122/97 RLLLPLPMFHVAALTTVIFSAMRGVTLISMPQFDATKVWSLIVEERVCIG
Rv3089|M.tuberculosis_H37Rv RLLLPLPMFHVAALTTVIFSAMRGVTLISMPQFDATKVWSLIVEERVCIG
MAB_4559|M.abscessus_ATCC_1997 RLLHSAPMFHMADFSAVLAGNLSGSTHVIVPSFSPQGVLDAIVAHDVQDM
MMAR_0466|M.marinum_M AALICVPPYHIAGVSAVLSNLYAGRKMVYLTNFDAHEWVRLTNAEQVTTA
MUL_1115|M.ulcerans_Agy99 AALICVPPYHIAGVSAVLSNLYAGRKMVYLNNFDAHEWVRLTNAEQVTTA
MAV_4950|M.avium_104 AALICVPPYHIAGVSAALSNLYAGRKMVYLPNFDAREWVRLINAENVTTA
Mflv_2385|M.gilvum_PYR-GCK AALICVPPYHIAGVSAALSNLYAGRKMVYLRHFDAEKWVRLVADEGVTSA
Mvan_4263|M.vanbaalenii_PYR-1 AALICVPPYHIAGVSAALSNLYAGRKMVYLTQFDAGRWVDLVTGEGVTSA
MSMEG_4883|M.smegmatis_MC2_155 AALICVPPYHIAGVSAAMSNLYAGRKMVYLRNFDAHRWVELVRTEGVTSA
TH_4415|M.thermoresistible__bu AMLISTPPYHIAGMGAVLSNLYAGRRIVYLPDFTAADWLATVREERITNA
MLBr_02546|M.leprae_Br4923 VTLLPAPMFHALGYLHATLAMFLGSTLVLRRRFKPATVLEDIEKHQATAM
* * :* . * : * . .
Mb3116|M.bovis_AF2122/97 GAVPAILNFMRQVPEFAEL------DAPDFRYFITGGAPMPEALIK--IY
Rv3089|M.tuberculosis_H37Rv GAVPAILNFMRQVPEFAEL------DAPDFRYFITGGAPMPEALIK--IY
MAB_4559|M.abscessus_ATCC_1997 LLVPTMIQMLVDHPGAAQL------DLSGIRSITYGASVISEAVLQRATR
MMAR_0466|M.marinum_M TVVPTMLDRIVAVLETGEH------KLPSLRNLAYGGSKVGLPLVRRALE
MUL_1115|M.ulcerans_Agy99 TVVPTMLDRIVAVLETGEH------KLPSLRNLAYGCSKVGLPLVRRALE
MAV_4950|M.avium_104 TVVPTMLDRIVTVLENGDPDTGAPIELPSLRNLAYGGSKVGLPLVRRALE
Mflv_2385|M.gilvum_PYR-GCK TVVPTMLDRIVTVLETTDT------ALPTLRTLAYGGSKVPLPLVRKALS
Mvan_4263|M.vanbaalenii_PYR-1 TVVPTMLDRIVSVLETRGT------TLPTLRTLAYGGSKVPLPLVRKALS
MSMEG_4883|M.smegmatis_MC2_155 TVVPTMLDRIVTALETTRA------ELPTLRNLAYGGSKVALPLVRKALE
TH_4415|M.thermoresistible__bu MVVPTMLARIVEYLDGEPA------RVPTLASLAYGGARLPQSVLERALR
MLBr_02546|M.leprae_Br4923 VVVPVMLSRILDTLENLETKS----DLSSLRVVFVSGSQLGAELATRALE
**.:: : . : . . : : :
Mb3116|M.bovis_AF2122/97 AAKNIEVVQGYALTESCGGGTLLLS---------EDALR--KAGSAGRAT
Rv3089|M.tuberculosis_H37Rv AAKNIEVVQGYALTESCGGGTLLLS---------EDALR--KAGSAGRAT
MAB_4559|M.abscessus_ATCC_1997 VFPNARFTQAYGMTEVSPVATLLLP---------DDHDDPALLRSAGRAA
MMAR_0466|M.marinum_M LLPDVGFVNAYGLTETSSTIAVLTPDDHRAAQSAAAAGLARRLGSVGRPV
MUL_1115|M.ulcerans_Agy99 LLPDVGFVNAYRLTETSSTIAVLTPDDHRAAQSAAAAGLARRLGSVGRPV
MAV_4950|M.avium_104 LLPHVGFVNAYGLTETSSTIAVLTPDDHRAALAATTPEAARRLGSVGQAV
Mflv_2385|M.gilvum_PYR-GCK LLPDVGFVNAYGLTETSSTIAVLTPDDHRAALAAADDAALRRLGSVGQPV
Mvan_4263|M.vanbaalenii_PYR-1 LLPAVGFVNAYGLTETSSTIAVLTPDDHRAALAASDEAAIRRLGSVGQPV
MSMEG_4883|M.smegmatis_MC2_155 LMPNVGFVNAYGLTETSSTIAVLGPDDHRAALASDDPGVTRRLGSVGQVV
TH_4415|M.thermoresistible__bu AFPDTGFINAYGLTETSSTIAVLGPEEHRDAMS--DSQLRHRLSSAGRIV
MLBr_02546|M.leprae_Br4923 ELGPVIYN-MYGSTEIAFATIAGPK------------DLQINSATVGPVV
* ** . :.* .
Mb3116|M.bovis_AF2122/97 MFTDVAVRG-DDG-VIREHGEGEVVIKSDILLKEYWNRPEATRDAFDNGW
Rv3089|M.tuberculosis_H37Rv MFTDVAVRG-DDG-VIREHGEGEVVIKSDILLKEYWNRPEATRDAFDNGW
MAB_4559|M.abscessus_ATCC_1997 PHCEVRIVDPDDN-EVPRGEIGEVIVKGDNVMLGYWELPEESAAAIRDGW
MMAR_0466|M.marinum_M PGVELQIRGQDGR-VLGPGETGELFVRGGQVSGRYTGI---GSVLDGHGW
MUL_1115|M.ulcerans_Agy99 PGVELQIRGQDGR-VLGPGETGELFVRGEQVSGRYTGI---GSVLDGHGW
MAV_4950|M.avium_104 AGIELQIRDEAGN-VLPPGETGELFVRGEQVSGRYTGI---GSVLDEDGW
Mflv_2385|M.gilvum_PYR-GCK PGIEVEVRAEDGT-VLGPGETGELFVRGEQVSGKYTDI---GSVLDENGW
Mvan_4263|M.vanbaalenii_PYR-1 PGIEVEIRADDGT-VLGAGETGELFVRGEQVSGKYTDI---GSVLDEQGW
MSMEG_4883|M.smegmatis_MC2_155 PGIEVQIRGEDGT-VLGPGETGELFVRGEQVSGRYTEI---GSVLDEDGW
TH_4415|M.thermoresistible__bu PGVEVQIRDEDGTTVLPEGETGLLWVRGAQVSGEYLGS---GSVLDGSGW
MLBr_02546|M.leprae_Br4923 KGVKVKILDDSGK-EVPRGQVGRIFVGNAFPFEGYTGG---GGKQIIDGL
.: : . : * : : . * *
Mb3116|M.bovis_AF2122/97 FRTGDIGEIDDEGYLYIKDRLKDMIISGGENVYPAEIESVIIGVPGVSEV
Rv3089|M.tuberculosis_H37Rv FRTGDIGEIDDEGYLYIKDRLKDMIISGGENVYPAEIESVIIGVPGVSEV
MAB_4559|M.abscessus_ATCC_1997 MHTGDAGRMDDRGYVYIVDRIKDMVVTGGENVYSAEVENALAKHPAVAAC
MMAR_0466|M.marinum_M FGTKDIAMLDEDGYLFIGGRSDDTIIRGGENIAPAELEEVLIEHPQVRDV
MUL_1115|M.ulcerans_Agy99 FGTKDIAMLDEDGYLFIGGRSDDTIIRGGENIAPAELEEVLIEHPQVRDV
MAV_4950|M.avium_104 FPTRDIAMLDDEGYLFIGGRSDDTIIRGGENIAPAELEEVLVEHPHVRDV
Mflv_2385|M.gilvum_PYR-GCK FPTKDVAYLDSEGYLFIGGRSDDTIIRGGENIAPAEIEDVLVEHPHVRDC
Mvan_4263|M.vanbaalenii_PYR-1 FPTKDVAFLDEEGYLFIGGRSDDTIIRGGENIAPAEIEDVLVEHPHVRDC
MSMEG_4883|M.smegmatis_MC2_155 FPTKDVAMLDQDGYLFIGGRSDDTIIRGGENIAPAEIEDVLVEHPDVRDV
TH_4415|M.thermoresistible__bu FPTRDRARIED-GFLYIGGRADDTIIRGGENISPAEIEDVLVHHDGVREV
MLBr_02546|M.leprae_Br4923 LSSGDVGYFDEHDLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVVEA
: : * . ::. . ::* .* .: :: ****: .**:*. : *
Mb3116|M.bovis_AF2122/97 AVIGLPDEKWGEIAAAIVVAD-QNEVSEQQIVEYCGTRLARYKLPKKVIF
Rv3089|M.tuberculosis_H37Rv AVIGLPDEKWGEIAAAIVVAD-QNEVSEQQIVEYCGTRLARYKLPKKVIF
MAB_4559|M.abscessus_ATCC_1997 AVIGIPDEQWGERVHAVVVKQAQSECCDGDLQEHCREHIANYKVPRSFEF
MMAR_0466|M.marinum_M AVVGVEDAQWGQEIVAVVVPVAGVDPDPEELREFVRRSLRGSRTPDRVVF
MUL_1115|M.ulcerans_Agy99 AVVGVEDAQWGQEIVAVVVPVAGVDPDPEELREFVRRSLRGSRTPDRVVF
MAV_4950|M.avium_104 AVVGVEDPQWGQAIVAVVVPAAGVEPDPEELREFVRKSLRGSRTPDEVVF
Mflv_2385|M.gilvum_PYR-GCK AVVGADDPQWGQIIVAVVVPHQDTAPDPEDLRAHVRSQLRGSRTPDRVVF
Mvan_4263|M.vanbaalenii_PYR-1 AVVGADDPEWGQIIVAVVVAQPGTEPDVEDLRSHVRSQLRGSRTPDRVVF
MSMEG_4883|M.smegmatis_MC2_155 AVVGPEDPQWGQIIVAVVVPADGAEPDADVLREHVRKHLRGSRTPDRVVF
TH_4415|M.thermoresistible__bu AVVGLPDEEWGERICAVIVPVDGSHAEPDQVREWCHARLRGSRTPDEVVF
MLBr_02546|M.leprae_Br4923 TAIGVDDKEWGARLRAFVVKKQDATIDEDAIKAYVRDHLARYKVPREVIF
:.:* * :** *.:* : : : * . *
Mb3116|M.bovis_AF2122/97 AEAIPRNPTGKILKTVLREQYSATVPK-----
Rv3089|M.tuberculosis_H37Rv AEAIPRNPTGKILKTVLREQYSATVPK-----
MAB_4559|M.abscessus_ATCC_1997 VDELPLSGAGKILKRVLRQKYWESRDAGVS--
MMAR_0466|M.marinum_M RHELPTTATGKILRREIIEELAGTKS------
MUL_1115|M.ulcerans_Agy99 RRELPTTATGKILRREIIEELAGTKS------
MAV_4950|M.avium_104 RDELPTTATGKVLRREIIATLAGLRAAPAQQ-
Mflv_2385|M.gilvum_PYR-GCK RDELPTNATGKVLRRELVSELNQDRSPAQPAV
Mvan_4263|M.vanbaalenii_PYR-1 RDELPTNATGKVLRRELVDELNQDPSPAQPAV
MSMEG_4883|M.smegmatis_MC2_155 RAELPTNATGKVLRRQLVDEL-------QPIS
TH_4415|M.thermoresistible__bu VDDLPKNATGKVLRRDIVEKLTEGVAMSG---
MLBr_02546|M.leprae_Br4923 LEELPRNPTGKVLKRELRDFEVH---------
:* . :**:*: :