For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2983 | - | - | 100% (454) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_2736 | - | e-148 | 55.79% (484) | PUTATIVE virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_3681 | - | e-146 | 54.87% (483) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0180 | mce1F | 2e-79 | 37.70% (435) | MCE-family protein MCE1F |
| M. gilvum PYR-GCK | Mflv_2106 | - | 1e-145 | 54.47% (481) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv1971 | mce3F | 1e-153 | 60.04% (458) | MCE-family protein MCE3F |
| M. leprae Br4923 | MLBr_02594 | mce1F | 2e-75 | 36.26% (444) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4148c | - | 7e-75 | 37.69% (451) | MCE-family protein |
| M. marinum M | MMAR_4056 | mce3F_1 | 1e-162 | 59.63% (483) | MCE-family protein Mce3F_1 |
| M. avium 104 | MAV_2537 | - | 1e-155 | 55.21% (489) | virulence factor mce family protein |
| M. smegmatis MC2 155 | MSMEG_0351 | - | 1e-147 | 55.60% (491) | virulence factor mce family protein |
| M. ulcerans Agy99 | MUL_3923 | mce3F_1 | 1e-163 | 59.63% (483) | MCE-family protein Mce3F_1 |
| M. vanbaalenii PYR-1 | Mvan_3977 | - | 1e-168 | 62.74% (475) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1971|M.tuberculosis_H37Rv MLHLPRRVIVQLAVFTVIAVGVLAITFLHFVRLPAMLFGVGRYTVTMELV
MSMEG_0351|M.smegmatis_MC2_155 MIH--RRTKIQLAIFCVIAVVFGTVMIFGYMRLPAHLFGIGLYTVNLDLD
Mvan_3977|M.vanbaalenii_PYR-1 -MRLDRRMKIQLALFAVIALMAMGVMGVHFMKLPAKLFGVGRYTVTVQLP
TH_2983|M.thermoresistible__bu MLH--RRIKIQLVIFAVIAMTAMALMSTQYMRLPAKLFGIGRYSVIVQLP
MAV_2537|M.avium_104 MLHLTRRTKIQLAIFTVISLSAASLMFFDYMQIPTVFFGVDRYTVTVELP
MMAR_4056|M.marinum_M -MRLTRQIFIQMAIFAIVATTALLIMVFGYMRVP-AMVGIGQYRVTVELP
MUL_3923|M.ulcerans_Agy99 -MRLTRQIFIQMAIFAIVATTALLIMVFGYMRVP-AMVGIGQYRVTVELP
Mflv_2106|M.gilvum_PYR-GCK -MRVTRQMLIQLLIFSLLAVTALGIMVFGYMRLP-EMIGIGQYKVTLELP
MAB_4148c|M.abscessus_ATCC_199 ---MERLIKIQLAIFAAVTVISVALMAIFYLRVP-TALGIGKHDVKAQFV
Mb0180|M.bovis_AF2122/97 --MLTRFIRRQLILFAIVSVVAIVVLGWYYLRIP-SLVGIGQYTLKADLP
MLBr_02594|M.leprae_Br4923 --MLTPLIRRQLVLFAILTVISLTVLGVYYLQIP-SLVGIGRYSLKAELS
*: :* :: : ::::* .*:. : : ::
Rv1971|M.tuberculosis_H37Rv EAGGLYRTGNVTYRGFEVGRVAAVRLTDTG-VQAVLALKSGIDIPSDLKA
MSMEG_0351|M.smegmatis_MC2_155 RTGGLYPTGNVTYRGTEVGRVESVGLSENGGVRAVLKLKSGIDIPSDLRA
Mvan_3977|M.vanbaalenii_PYR-1 QAGGLYSGGNVTYRGTEVGRVEAVRLTPGG-VDAVLSLKSGIDVPSDLRA
TH_2983|M.thermoresistible__bu EAAGLYPRGNVTYRGVEVGIVDSLHLTDTG-VDAVLSLKSGIDIPSDVTA
MAV_2537|M.avium_104 QAGGLYPGGNVTYRGVEVGRVQAVKLTATG-AEAVLQLNSDVHIPANLNA
MMAR_4056|M.marinum_M EAGGLYPRSNVTYRGVEVGTVKSVHLTNTG-VAAVLSLNSDVKIPADVEA
MUL_3923|M.ulcerans_Agy99 EAGGLYPRSNVTYRGVEVGTVKSVHLTNTG-VAAVLSLNSDVKIPADVEA
Mflv_2106|M.gilvum_PYR-GCK ETGGLYERSNVTYRGSQVGIVESVGLTDRG-VAAELSLNSDVSIPADLIA
MAB_4148c|M.abscessus_ATCC_199 ASGGLYQNANVTFRGVQIGRVTDVELTPEG-VTATMRLNDNVKVPGNVVA
Mb0180|M.bovis_AF2122/97 ASGGLYPTANVTYRGITIGKVTAVEPTDQG-ARVTMSIASNYKIPVDASA
MLBr_02594|M.leprae_Br4923 ATGGLYPTANVTYRGIAIGKVTDVEPTATG-AEATMSIDSRYKIPIDSAA
:.*** .***:** :* * : : * . . : : . :* : *
Rv1971|M.tuberculosis_H37Rv EVHSHTAIGETYVELLPR-NAASPPLKNGDVIALADTSVPPDINDLLSAA
MSMEG_0351|M.smegmatis_MC2_155 EVHSQSAIGEQYVELLPR-SAAAPPLQDGDVIAAKDVFIPPDINSLLDAA
Mvan_3977|M.vanbaalenii_PYR-1 EVHSQSAIGEQYVALLPR-SGDARPLRDGDVITPADTSVPPNVNTLLADA
TH_2983|M.thermoresistible__bu EVHSQSAIGEQYVMLLPR-DGTSPPLKDGDVIPPEQTRVPADINAILADA
MAV_2537|M.avium_104 QVHSVSAVGEQYVELLPR-GGQGPSLKNGDVIPVDRSYVPPDINSLLAAT
MMAR_4056|M.marinum_M EVHSVSSVGEQYVQLLPR-SGQGPSLKDGDVIPSSRTRVPTDINTILDET
MUL_3923|M.ulcerans_Agy99 EVHSVSSVGEQYVQLLPR-SGQGPSLKDGDVIPSSRTRVPTDINTILDET
Mflv_2106|M.gilvum_PYR-GCK SVRSQSAVGEQFVELVPQ-SGDGPALRNGDVISRDRARVPADVNTVLELT
MAB_4148c|M.abscessus_ATCC_199 AVKSVSAIGEQYVDLIPPPTGAAGTLRSGDVIGADRTSIPTDVSTLLRQA
Mb0180|M.bovis_AF2122/97 NVHSVSAVGEQYIDLVST-GAPGKYFSSGQTIT--KGTVPSEIGPALDNS
MLBr_02594|M.leprae_Br4923 NVHSVSAVGEQYLDLVSS-GNPGKYLAPGQTIT--KSKIPIEIGPALDSV
*:* :::** :: *:. . : *:.* :* ::. *
Rv1971|M.tuberculosis_H37Rv NTALEAIPHENLQTVIDESYTAVAGLGLELSRLIKGSAELAIDARANLDP
MSMEG_0351|M.smegmatis_MC2_155 NTGLQAIPQDNLKTAIDESYAAVGGLGPAISRLVRGSTALASDARKNLGS
Mvan_3977|M.vanbaalenii_PYR-1 NVGLQAIPRDNLQTVVEESYAAVGGLGPELSRIVDSSTKLAIEARRHLDP
TH_2983|M.thermoresistible__bu VTGLQAVPKDGLQTLIDESYTAVGGLGPELRRIVSASIDLSLDARDNLDP
MAV_2537|M.avium_104 NRGLTVIPRDNLKTVVDESYTAVGGLGPELSRLVSGTAKLATDSRQNLDA
MMAR_4056|M.marinum_M NRGLQAIPRENLKTVVDEAAVAVGGLGPELRRLITGSSKLAIDARANLDE
MUL_3923|M.ulcerans_Agy99 NRGLQAIPRENLKTVVDEAAVAVGGLGPELRRLITGSSKLAIDARANLDE
Mflv_2106|M.gilvum_PYR-GCK NEGLRAIPQDNLRTVVDEAYEAVGGLGPELRRLVNGSSQLAIDARANLDS
MAB_4148c|M.abscessus_ATCC_199 DGLVNTVADTRLREVLAEAFKAFNGSGQELSRLIDSSRLLIQEANTNYDS
Mb0180|M.bovis_AF2122/97 NRGLAALPTEKIGLLLDETAQAVGGLGPALQRLVDSTQAIVGDFKTNIGD
MLBr_02594|M.leprae_Br4923 NRGLAALPKEKIGSLLDETAQAVGGLGPALQRLVSSTQAIVDAFKTNITD
: .:. : : *: *. * * : *:: .: : . :
Rv1971|M.tuberculosis_H37Rv LVALIDRAGPVLDSQTHTSDAIAAWAAQLAAVTGQLQTHDSAVGDLIDRG
MSMEG_0351|M.smegmatis_MC2_155 LTTLIDLWQPVAESQIGTADSIEAWAANLAAVTGQLKQHNADVVGLIEQG
Mvan_3977|M.vanbaalenii_PYR-1 LITLIDQSQPVLDSQTRTSEAIQAWAAQVATVTTQLQTQDQTLARVIDDG
TH_2983|M.thermoresistible__bu LVELIEKSQPVLDSQTDTSQAIRAWASQVATVTDSLRNHDAQLAGVLHQG
MAV_2537|M.avium_104 LVNLIDGSKPLLDSQTQSADSVQAWAAHLATITSELRDNDSSVAGLLREG
MMAR_4056|M.marinum_M LTLLIDQSKPVLDTQTDTAGAIRSWASNLASITDQLQRQDSSLAGLLDQG
MUL_3923|M.ulcerans_Agy99 LTLLIDQSKPVLDTQTDTAGAIRSWASNLASITDQLQRQDSSLAGLLDQG
Mflv_2106|M.gilvum_PYR-GCK LTTVIDESKPVLDSQIETSGSIRAWASNLADLTGQLQSQDAAVSGILSNG
MAB_4148c|M.abscessus_ATCC_199 TTKLIDQVGPLLDAQIRSGDNIRGSVSSLAALTEHFAKADPQLRQFLKVA
Mb0180|M.bovis_AF2122/97 VNDIIENSGPILDSQVNTGDQIERWARKLNNLAAQTATRDQNVRSILSQA
MLBr_02594|M.leprae_Br4923 VNDIIQNSGPILDSQVKSDNAIERWVHNLNVLAAQSARQDQHLKSILSQA
:*: *: ::* : : . : :: : : .: .
Rv1971|M.tuberculosis_H37Rv GPALGETRQLLERLQPTVPILLANLVSVGQVALTYHNDIEQLLVVFPMAI
MSMEG_0351|M.smegmatis_MC2_155 APAAEEARRLFERVQPTLPILLANLVSINEVAVTYQPGIEQILVLLPQGI
Mvan_3977|M.vanbaalenii_PYR-1 GESADAVRQLVDRVKPTLPIVLANLVSVGQVAVTYHDNIEQLLVLFPAVV
TH_2983|M.thermoresistible__bu GPAFADTRDLIDRLHPTLPSTVAHLATLGDVAHQYHPAVEQLLVLFPQAI
MAV_2537|M.avium_104 GPAAAEARQLFDRLSPTLPIVLANLVSVGQVGVTYRDNLESLLVELPQGV
MMAR_4056|M.marinum_M PGAADEVRALFNRLRPTLPIVLANLVSVGEVAVAYHPSLEQLLVLFPQGT
MUL_3923|M.ulcerans_Agy99 PGAADEVRALFNRLRPTLPIVLANLVSVGEVAVAYHPSLEQLLVLFPQGT
Mflv_2106|M.gilvum_PYR-GCK PGAAEETRALFDRIKPTLPIVLANLISVGEVAVAYQPNLEQLLVLLPQGT
MAB_4148c|M.abscessus_ATCC_199 PGASEQASQLFAGIRPSFPVLAASLANLGRVGVIYNKSIEQSLVILPALF
Mb0180|M.bovis_AF2122/97 APTADEVNAVFSGVRDSLPQTLANLEVVFDMLKRYHAGVEQLLVFLPQGA
MLBr_02594|M.leprae_Br4923 APTADEVNTVFSDVRDSLPQTLANFEILIDMLKRYHHGVEQMLVFLPQGA
: . :. : :.* * : : : *. :*. ** :*
Rv1971|M.tuberculosis_H37Rv AAEQAGILANLNTK-QAYRGQYLSFNLNLNLPPPCTTGFLPAQQRRIPTF
MSMEG_0351|M.smegmatis_MC2_155 AQLQGPNLANRDNKDTAHKGMFLAFNTNINLPPPCTTGFLPAQQRRPPSF
Mvan_3977|M.vanbaalenii_PYR-1 SAEQAGLVANLHTK-QDYKGQYLSFNLNINLPPPCTTGFLPAQQQRSPVF
TH_2983|M.thermoresistible__bu AEAQATHLANRNTE-QDYRGQYLSFNLNLNLPPPCTTGFLPAQQQRSPVH
MAV_2537|M.avium_104 AEIQATGVANRNTK-QDYNGAFLSFNLNLNWPPPCTTGFLPIQQQRAASY
MMAR_4056|M.marinum_M AVTQAVGVAKRNTI-QDYKGDYLVFNLNLNLPPPCTTGFLPAQQQRVPTF
MUL_3923|M.ulcerans_Agy99 AVTQAVGVAKRNTI-QDYKGDYLVFNLNLNLPPPCTTGFLPAQQQRVPTF
Mflv_2106|M.gilvum_PYR-GCK AVTQAVGVAKNGTK-QDYMGDYLVFNLNLNVPPPCTTGFLPAQQQRAPTF
MAB_4148c|M.abscessus_ATCC_199 SALLTVAGGAPMDE-----GAKLDFRLNLGDPPPCLTGFVPPPLMRTPAD
Mb0180|M.bovis_AF2122/97 AIAQTVLTPTPGAA-------QLPLAPAINYPPPCLTGFLPASEWRSP-A
MLBr_02594|M.leprae_Br4923 SIAQTASATFPNMA-------ALDLALSINQPPPCLTGFIPAAEWRSP-A
: * : :. **** ***:* * .
Rv1971|M.tuberculosis_H37Rv EDYPDRPAGDLYCRVPQDSPFN-VRGARNIPCETVPGKRAPTVKLCESDA
MSMEG_0351|M.smegmatis_MC2_155 EDYPERPAGDLYCRTPQDSPFN-ARGARNIPCETVPGKRAPTVKLCESDE
Mvan_3977|M.vanbaalenii_PYR-1 EDAPERPPGDLYCRVPQDSPLN-VRGAHNIPCATRPGKRAPTVAICESDE
TH_2983|M.thermoresistible__bu EDHPPREPGLLYCRTPQDSMWN-VRGAKNYPCITRPGKRAPTAQMCESDE
MAV_2537|M.avium_104 EDYPDSPNGDIYCRVPQDSVLN-VRGARNMPCETRPGKRAPTVKMCESDQ
MMAR_4056|M.marinum_M EDYPNRAPGDLYCRVPQDAPFN-VRGARNLPCVTVPGKRAPTAKLCESNE
MUL_3923|M.ulcerans_Agy99 EDYPNRAPGDLYCRVPQDAPFN-VRGARNLPCVTVPGKRAPTAKLCESNE
Mflv_2106|M.gilvum_PYR-GCK EDAPDRPRGDLYCRVPQDSAFN-VRGARNIPCATVPGKRAPSAAMCESGE
MAB_4148c|M.abscessus_ATCC_199 ETLRELPR-DMYCKTAQNDPSA-VRGARNYPCQEFPGKRAPTIQLCRDPR
Mb0180|M.bovis_AF2122/97 DTSPRPLPSGTYCKIPQDAQLQ-VRGARNIPCVDVPGKRAATPKECRSKD
MLBr_02594|M.leprae_Br4923 DTSLQPLPVGTYCKIPMDTPANSVRGSRNIPCVDVPGKRAASPRECRDSK
: **: . : .**::* ** *****.: *..
Rv1971|M.tuberculosis_H37Rv PYLPLNDGYNWKG----------DPNATVPG-------------------
MSMEG_0351|M.smegmatis_MC2_155 NFVPLNDGYNWKG----------DPNATLSGQS----------------I
Mvan_3977|M.vanbaalenii_PYR-1 IYVPLNDGFNWKG----------DPNATSSGQP----------------V
TH_2983|M.thermoresistible__bu HYIPLNDGNNWKG----------DPNATLSGQD----------------I
MAV_2537|M.avium_104 TYVPLNDGFNWKG----------DPNATYSGQD----------------V
MMAR_4056|M.marinum_M VYVPLNDGYNWKG----------DPNSTLSGQP----------------I
MUL_3923|M.ulcerans_Agy99 VYVPLNDGYNWKG----------DPNSTLSGQP----------------I
Mflv_2106|M.gilvum_PYR-GCK VYVPLNEGYIWKG----------DPNATLSGQA----------------V
MAB_4148c|M.abscessus_ATCC_199 GYVPIGSN-PWRGPPAPYDTPVEDPRNILPPNK----------------F
Mb0180|M.bovis_AF2122/97 PYVPLGTN-PWFG----------DPNQILTCPAPGARCDQPVKPGLVIPA
MLBr_02594|M.leprae_Br4923 PYVPLGTN-PWFG----------DPNQLLTCPAPGARCDQPVKPGLVIPA
::*:. . * * **. .
Rv1971|M.tuberculosis_H37Rv --LGSGQ-------------------------------------------
MSMEG_0351|M.smegmatis_MC2_155 PDLGPGQGESAPETSPAPPAPPVEGDPVP---------------------
Mvan_3977|M.vanbaalenii_PYR-1 PQLPPAAG--------------PQAAPPA---------------------
TH_2983|M.thermoresistible__bu PQLPPGTS------------------------------------------
MAV_2537|M.avium_104 PQYRPGEEPPGQ----VPPPSPPGPAPPP---------------------
MMAR_4056|M.marinum_M PQLPP-EPPLEQS------APPGPAPPAP---------------------
MUL_3923|M.ulcerans_Agy99 PQLPP-EPPLEQS------APPGPAPPAP---------------------
Mflv_2106|M.gilvum_PYR-GCK PQLRPGQQPAQAS------PPPGPAPP-P---------------------
MAB_4148c|M.abscessus_ATCC_199 PNIPPGAEPDPGTPTLPPPSPPAPEVPPAGGDVMPVSAQS--------GP
Mb0180|M.bovis_AF2122/97 PSINTGLNPAPADQVQGTPPPVSDPLQRPGSGTVQCNGQQPNPCVYTPTS
MLBr_02594|M.leprae_Br4923 PTVDNGLNPAPADRLPGTPPPVSDPLSQPRSGSVQCNGQQPNTCVYTPSG
Rv1971|M.tuberculosis_H37Rv ------------------------DIP------QTWQTMLLPPGS-
MSMEG_0351|M.smegmatis_MC2_155 MAIARYDPATGTYLGPDGQVYTQADLADNGSKEQTWQSMLTPHGMN
Mvan_3977|M.vanbaalenii_PYR-1 LAAAEYDPATGSYIGPDGRSYTQADLAQGAPAGQTWQTMLLPPGS-
TH_2983|M.thermoresistible__bu -----------------QTPPAEPGDPTTDPREQTWQSMLLPPR--
MAV_2537|M.avium_104 IAAVQYDPATGMYMGPDGRMYTQTDLAVGTKKGQTWQSMLMPPKRN
MMAR_4056|M.marinum_M IAAAEYDPATGTYMGPDGHLYTQANLGQTVPEEQTWQTMLLPPKK-
MUL_3923|M.ulcerans_Agy99 IAAAEYDPATGTYMGPDGHLYTQANLGQTVPEEQTWQTMLLPPKK-
Mflv_2106|M.gilvum_PYR-GCK MAAAEYDPANGTYVGPDGRVYTQSNLAEGATEEQTWQTMLLPPKGN
MAB_4148c|M.abscessus_ATCC_199 MAARAYDPKNGVFLDANNQPSVYAPALDRGTEAETWADLMLGPKPV
Mb0180|M.bovis_AF2122/97 GPSAVYSPASGELVGPDGVKYAVANSSTTG--DDGWKEMLAPAS--
MLBr_02594|M.leprae_Br4923 PPSAVYSPQSGELVGPDGVAYAVENSTKTG--DDGWKEMLAPAG--
: * ::