For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_3681 | - | - | 100% (488) | virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_2736 | - | e-164 | 58.25% (491) | PUTATIVE virulence factor Mce family protein |
| M. thermoresistible (build 8) | TH_3702 | - | e-162 | 57.73% (485) | PUTATIVE virulence factor Mce family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0610 | mce2F | 1e-85 | 37.24% (529) | MCE-family protein MCE2F |
| M. gilvum PYR-GCK | Mflv_2106 | - | 1e-171 | 60.16% (487) | virulence factor Mce family protein |
| M. tuberculosis H37Rv | Rv1971 | mce3F | 1e-151 | 62.68% (426) | MCE-family protein MCE3F |
| M. leprae Br4923 | MLBr_02594 | mce1F | 4e-81 | 34.77% (532) | putative secreted protein |
| M. abscessus ATCC 19977 | MAB_4148c | - | 3e-84 | 36.70% (515) | MCE-family protein |
| M. marinum M | MMAR_2887 | mce3F | 1e-173 | 60.62% (485) | MCE-family protein Mce3F |
| M. avium 104 | MAV_2537 | - | 1e-170 | 59.22% (488) | virulence factor mce family protein |
| M. smegmatis MC2 155 | MSMEG_0351 | - | 1e-165 | 59.06% (491) | virulence factor mce family protein |
| M. ulcerans Agy99 | MUL_2865 | mce3F | 1e-173 | 60.62% (485) | MCE-family protein Mce3F |
| M. vanbaalenii PYR-1 | Mvan_3977 | - | 1e-176 | 62.83% (487) | virulence factor Mce family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2887|M.marinum_M -MHLERRVMIQLTIFAVIALSVLAITFLHFAKLPAMLFGVGRYTVTMELT
MUL_2865|M.ulcerans_Agy99 -MHLERRVMIQLTIFAVIALSVLAITFLHFAKLPAMLFGVGRYTVTMELT
Rv1971|M.tuberculosis_H37Rv MLHLPRRVIVQLAVFTVIAVGVLAITFLHFVRLPAMLFGVGRYTVTMELV
Mvan_3977|M.vanbaalenii_PYR-1 -MRLDRRMKIQLALFAVIALMAMGVMGVHFMKLPAKLFGVGRYTVTVQLP
MSMEG_0351|M.smegmatis_MC2_155 --MIHRRTKIQLAIFCVIAVVFGTVMIFGYMRLPAHLFGIGLYTVNLDLD
Mflv_2106|M.gilvum_PYR-GCK -MRVTRQMLIQLLIFSLLAVTALGIMVFGYMRLP-EMIGIGQYKVTLELP
MAV_2537|M.avium_104 MLHLTRRTKIQLAIFTVISLSAASLMFFDYMQIPTVFFGVDRYTVTVELP
TH_3681|M.thermoresistible__bu -MNLTRRILLQLAVFVGVAVIAGSVMIVGVIKLPALALGVGRYTVTVELP
MAB_4148c|M.abscessus_ATCC_199 ---MERLIKIQLAIFAAVTVISVALMAIFYLRVP-TALGIGKHDVKAQFV
Mb0610|M.bovis_AF2122/97 --MLTRAIKTQLVLLTVLAVIAVVVLGWYFLRIP-SLVGIGRYTLYAELP
MLBr_02594|M.leprae_Br4923 --MLTPLIRRQLVLFAILTVISLTVLGVYYLQIP-SLVGIGRYSLKAELS
: ** :: ::: : ::* .*:. : : ::
MMAR_2887|M.marinum_M KSGGLYSSGNVTYRGSEVGRVESVQLTDTG-VVAVLSLKSGIDIPSDLKA
MUL_2865|M.ulcerans_Agy99 KSGGLYTSGNVTYRGSEVGRVESVQLTDTG-VVAVLSLKSGIDIPSDLKA
Rv1971|M.tuberculosis_H37Rv EAGGLYRTGNVTYRGFEVGRVAAVRLTDTG-VQAVLALKSGIDIPSDLKA
Mvan_3977|M.vanbaalenii_PYR-1 QAGGLYSGGNVTYRGTEVGRVEAVRLTPGG-VDAVLSLKSGIDVPSDLRA
MSMEG_0351|M.smegmatis_MC2_155 RTGGLYPTGNVTYRGTEVGRVESVGLSENGGVRAVLKLKSGIDIPSDLRA
Mflv_2106|M.gilvum_PYR-GCK ETGGLYERSNVTYRGSQVGIVESVGLTDRG-VAAELSLNSDVSIPADLIA
MAV_2537|M.avium_104 QAGGLYPGGNVTYRGVEVGRVQAVKLTATG-AEAVLQLNSDVHIPANLNA
TH_3681|M.thermoresistible__bu EAAGLYEGGNVTYRGTTVGRIRDVRLTDTG-VEAVLSLDSGIDIPSNLRA
MAB_4148c|M.abscessus_ATCC_199 ASGGLYQNANVTFRGVQIGRVTDVELTPEG-VTATMRLNDNVKVPGNVVA
Mb0610|M.bovis_AF2122/97 RSGGLYRTANVTYRGITIGKVTGVEPTERG-ARATMSIDNGYQIPTDASA
MLBr_02594|M.leprae_Br4923 ATGGLYPTANVTYRGIAIGKVTDVEPTATG-AEATMSIDSRYKIPIDSAA
:.*** .***:** :* : * : * . * : :.. :* : *
MMAR_2887|M.marinum_M EVHSQTAIGETYVELLPR-NATSPPLKDGDVIRLVNTSVPPDINTLLSAA
MUL_2865|M.ulcerans_Agy99 EVHSQTAIGETYVELLPR-NATSPPLKDGDVIRLVNTSVPPDINTLLSAA
Rv1971|M.tuberculosis_H37Rv EVHSHTAIGETYVELLPR-NAASPPLKNGDVIALADTSVPPDINDLLSAA
Mvan_3977|M.vanbaalenii_PYR-1 EVHSQSAIGEQYVALLPR-SGDARPLRDGDVITPADTSVPPNVNTLLADA
MSMEG_0351|M.smegmatis_MC2_155 EVHSQSAIGEQYVELLPR-SAAAPPLQDGDVIAAKDVFIPPDINSLLDAA
Mflv_2106|M.gilvum_PYR-GCK SVRSQSAVGEQFVELVPQ-SGDGPALRNGDVISRDRARVPADVNTVLELT
MAV_2537|M.avium_104 QVHSVSAVGEQYVELLPR-GGQGPSLKNGDVIPVDRSYVPPDINSLLAAT
TH_3681|M.thermoresistible__bu EVHSQSAVGEQYVALLPR-DGESPPLRDGDVVSRENVKVPPNINALVAAT
MAB_4148c|M.abscessus_ATCC_199 AVKSVSAIGEQYVDLIPPPTGAAGTLRSGDVIGADRTSIPTDVSTLLRQA
Mb0610|M.bovis_AF2122/97 NVHSVSAVGEQFVDLVST-RTSGPYLRHGQTIT--TTTVPSQIGPALDAA
MLBr_02594|M.leprae_Br4923 NVHSVSAVGEQYLDLVSS-GNPGKYLAPGQTIT--KSKIPIEIGPALDSV
*:* :*:** :: *:. . * *:.: :* ::. : .
MMAR_2887|M.marinum_M NTALGAIPHENLQTVINESYTAVGGLGPELSRLITGTSNLAIDARKNLDP
MUL_2865|M.ulcerans_Agy99 NTALGAIPHENLQTVINESYTAVGGLGPELSRLITGTSNLAIDARKNLDP
Rv1971|M.tuberculosis_H37Rv NTALEAIPHENLQTVIDESYTAVAGLGLELSRLIKGSAELAIDARANLDP
Mvan_3977|M.vanbaalenii_PYR-1 NVGLQAIPRDNLQTVVEESYAAVGGLGPELSRIVDSSTKLAIEARRHLDP
MSMEG_0351|M.smegmatis_MC2_155 NTGLQAIPQDNLKTAIDESYAAVGGLGPAISRLVRGSTALASDARKNLGS
Mflv_2106|M.gilvum_PYR-GCK NEGLRAIPQDNLRTVVDEAYEAVGGLGPELRRLVNGSSQLAIDARANLDS
MAV_2537|M.avium_104 NRGLTVIPRDNLKTVVDESYTAVGGLGPELSRLVSGTAKLATDSRQNLDA
TH_3681|M.thermoresistible__bu NRGLQAIPRENLETVVDESYNAVGGLGPELARLVSGSASLAIEARKNLDS
MAB_4148c|M.abscessus_ATCC_199 DGLVNTVADTRLREVLAEAFKAFNGSGQELSRLIDSSRLLIQEANTNYDS
Mb0610|M.bovis_AF2122/97 NRGLAVLPKDRVASVLHEASEAVGGLGSSLNRLIEATQAIAHDVRGSLED
MLBr_02594|M.leprae_Br4923 NRGLAALPKEKIGSLLDETAQAVGGLGPALQRLVSSTQAIVDAFKTNITD
: : .:. .: : *: *. * * : *:: .: : .
MMAR_2887|M.marinum_M LIALIDQTPPVLDSQTHSSDAIAGWASHLAAVTTELQTHDQAVAATIDNG
MUL_2865|M.ulcerans_Agy99 LIALIDQTPPVLDSQTHSSDAIAGWASHLAAVTTELQTHDQAVAATIDNG
Rv1971|M.tuberculosis_H37Rv LVALIDRAGPVLDSQTHTSDAIAAWAAQLAAVTGQLQTHDSAVGDLIDRG
Mvan_3977|M.vanbaalenii_PYR-1 LITLIDQSQPVLDSQTRTSEAIQAWAAQVATVTTQLQTQDQTLARVIDDG
MSMEG_0351|M.smegmatis_MC2_155 LTTLIDLWQPVAESQIGTADSIEAWAANLAAVTGQLKQHNADVVGLIEQG
Mflv_2106|M.gilvum_PYR-GCK LTTVIDESKPVLDSQIETSGSIRAWASNLADLTGQLQSQDAAVSGILSNG
MAV_2537|M.avium_104 LVNLIDGSKPLLDSQTQSADSVQAWAAHLATITSELRDNDSSVAGLLREG
TH_3681|M.thermoresistible__bu LTALIDQSQPVLDSQVDTSDSIARWARNLAALTAQLKIHDPAVRGLLDNG
MAB_4148c|M.abscessus_ATCC_199 TTKLIDQVGPLLDAQIRSGDNIRGSVSSLAALTEHFAKADPQLRQFLKVA
Mb0610|M.bovis_AF2122/97 IDDIIERSAPIIDSQVNSGNEIARWAANLNTLAAQTAQTDPAVRSILANA
MLBr_02594|M.leprae_Br4923 VNDIIQNSGPILDSQVKSDNAIERWVHNLNVLAAQSARQDQHLKSILSQA
:*: *: ::* : : . : :: . : : : .
MMAR_2887|M.marinum_M GPALDEVNSLLERVQPTLPILLANLVSVGQVALAYQNDIEQLLVVFPMAI
MUL_2865|M.ulcerans_Agy99 GPALDEVNSLLERVQPTLPILLANLVSVGQVALAYQNDIEQLLVVFPMAI
Rv1971|M.tuberculosis_H37Rv GPALGETRQLLERLQPTVPILLANLVSVGQVALTYHNDIEQLLVVFPMAI
Mvan_3977|M.vanbaalenii_PYR-1 GESADAVRQLVDRVKPTLPIVLANLVSVGQVAVTYHDNIEQLLVLFPAVV
MSMEG_0351|M.smegmatis_MC2_155 APAAEEARRLFERVQPTLPILLANLVSINEVAVTYQPGIEQILVLLPQGI
Mflv_2106|M.gilvum_PYR-GCK PGAAEETRALFDRIKPTLPIVLANLISVGEVAVAYQPNLEQLLVLLPQGT
MAV_2537|M.avium_104 GPAAAEARQLFDRLSPTLPIVLANLVSVGQVGVTYRDNLESLLVELPQGV
TH_3681|M.thermoresistible__bu AGAGEQGRLLFERLKPTLPVLMANLVSVGEVAVTYNAGIEQLLVLLPPSV
MAB_4148c|M.abscessus_ATCC_199 PGASEQASQLFAGIRPSFPVLAASLANLGRVGVIYNKSIEQSLVILPALF
Mb0610|M.bovis_AF2122/97 APTADQVNATFSDVRESLPQTLANLEVVIDMLKRYHNGVEQALVFLPQSG
MLBr_02594|M.leprae_Br4923 APTADEVNTVFSDVRDSLPQTLANFEILIDMLKRYHHGVEQMLVFLPQGA
: . : :.* *.: : : *. .:*. ** :*
MMAR_2887|M.marinum_M SAEQAGILANVNTK-QAYHGQYLSFN-LNLNLPPPCSTGFLPAQQQRVPI
MUL_2865|M.ulcerans_Agy99 SAEQAGILANVNTK-QAYHGQYLSFN-LNLNLPPPCSTGFLPAQQQRVPT
Rv1971|M.tuberculosis_H37Rv AAEQAGILANLNTK-QAYRGQYLSFN-LNLNLPPPCTTGFLPAQQRRIPT
Mvan_3977|M.vanbaalenii_PYR-1 SAEQAGLVANLHTK-QDYKGQYLSFN-LNINLPPPCTTGFLPAQQQRSPV
MSMEG_0351|M.smegmatis_MC2_155 AQLQGPNLANRDNKDTAHKGMFLAFN-TNINLPPPCTTGFLPAQQRRPPS
Mflv_2106|M.gilvum_PYR-GCK AVTQAVGVAKNGTK-QDYMGDYLVFN-LNLNVPPPCTTGFLPAQQQRAPT
MAV_2537|M.avium_104 AEIQATGVANRNTK-QDYNGAFLSFN-LNLNWPPPCTTGFLPIQQQRAAS
TH_3681|M.thermoresistible__bu AALQAAGVANFNTK-QDYKGAYLNFN-LNVNLPPPCVTGYFPTQQRRSPA
MAB_4148c|M.abscessus_ATCC_199 SALLTVAGGAPMDE-----GAKLDFR-LNLGDPPPCLTGFVPPPLMRTPA
Mb0610|M.bovis_AF2122/97 AIAQSVTTEFPGQA-------GLGVGGLALNQPPPCLTGFLPASEWRSPA
MLBr_02594|M.leprae_Br4923 SIAQTASATFPNMA-------ALDLA-LSINQPPPCLTGFIPAAEWRSPA
: * . :. **** **:.* * .
MMAR_2887|M.marinum_M FEDYPNRPAGDLYCRVPQDS-PLNVRGARNIPCETVPGKRAPTVKLCESD
MUL_2865|M.ulcerans_Agy99 FEDYPNRPAGDLYCRVPQDS-PLNVRGARNIPCETVPGKRAPTVNLCESN
Rv1971|M.tuberculosis_H37Rv FEDYPDRPAGDLYCRVPQDS-PFNVRGARNIPCETVPGKRAPTVKLCESD
Mvan_3977|M.vanbaalenii_PYR-1 FEDAPERPPGDLYCRVPQDS-PLNVRGAHNIPCATRPGKRAPTVAICESD
MSMEG_0351|M.smegmatis_MC2_155 FEDYPERPAGDLYCRTPQDS-PFNARGARNIPCETVPGKRAPTVKLCESD
Mflv_2106|M.gilvum_PYR-GCK FEDAPDRPRGDLYCRVPQDS-AFNVRGARNIPCATVPGKRAPSAAMCESG
MAV_2537|M.avium_104 YEDYPDSPNGDIYCRVPQDS-VLNVRGARNMPCETRPGKRAPTVKMCESD
TH_3681|M.thermoresistible__bu LVDSPDLPPGDVYCRVPQDSTVLAVRGARNIPCLNKPGKRAPTAQLCESD
MAB_4148c|M.abscessus_ATCC_199 DETLRELPR-DMYCKTAQND-PSAVRGARNYPCQEFPGKRAPTIQLCRDP
Mb0610|M.bovis_AF2122/97 DTSTAPLPK-GTYCRIPMDA-SNVVRGARNNPCVDVPGKRAATPRECRSN
MLBr_02594|M.leprae_Br4923 DTSLQPLPV-GTYCKIPMDTPANSVRGSRNIPCVDVPGKRAASPRECRDS
* . **: . : .**::* ** *****.: *..
MMAR_2887|M.marinum_M EQYVPLNDGYNWKG----------DPNSTL--------------SGQDIP
MUL_2865|M.ulcerans_Agy99 EQYVPLNDGYNWKG----------DPNSTL--------------SGQDIP
Rv1971|M.tuberculosis_H37Rv APYLPLNDGYNWKG----------DPNATV--------------PG----
Mvan_3977|M.vanbaalenii_PYR-1 EIYVPLNDGFNWKG----------DPNATS--------------SGQPVP
MSMEG_0351|M.smegmatis_MC2_155 ENFVPLNDGYNWKG----------DPNATL--------------SGQSIP
Mflv_2106|M.gilvum_PYR-GCK EVYVPLNEGYIWKG----------DPNATL--------------SGQAVP
MAV_2537|M.avium_104 QTYVPLNDGFNWKG----------DPNATY--------------SGQDVP
TH_3681|M.thermoresistible__bu EEYTPLNDGMNWKG----------DPNATL--------------SGQDIP
MAB_4148c|M.abscessus_ATCC_199 RGYVPIGS-NPWRGPPAPYDTPVEDPRNIL--------------PPNKFP
Mb0610|M.bovis_AF2122/97 EAYVPGGT-NPWYG----------DPNQMLSCPAPAARCDQPVKPGQVIP
MLBr_02594|M.leprae_Br4923 KPYVPLGT-NPWFG----------DPNQLLTCPAPGARCDQPVKPGLVIP
: * . * * **. .
MMAR_2887|M.marinum_M QLPPG-------PSPPAAAGPGEAPPPP----------------------
MUL_2865|M.ulcerans_Agy99 QLPPG-------PPPPAAAGPGEAPPPP----------------------
Rv1971|M.tuberculosis_H37Rv ------------------LGSGQDIP------------------------
Mvan_3977|M.vanbaalenii_PYR-1 QLPP--------------AAGPQAAPPA----------------------
MSMEG_0351|M.smegmatis_MC2_155 DLGPGQGESAPETSPAPPAPPVEGDPVP----------------------
Mflv_2106|M.gilvum_PYR-GCK QLRPG----QQP-AQASPP--PGPAPPP----------------------
MAV_2537|M.avium_104 QYRPG----EEPPGQVPPPSPPGPAPPP----------------------
TH_3681|M.thermoresistible__bu EVRRG-------PGAAQVSTSGPVAPPS----------------------
MAB_4148c|M.abscessus_ATCC_199 NIPPGAEPDPGTPTLPPPSPPAPEVPPAGGDVMPVSAQ----------SG
Mb0610|M.bovis_AF2122/97 APSVNNGINPLPADQLPGTPPPVNDPLQRPGSGTVQCNGQQPNPCVYTPS
MLBr_02594|M.leprae_Br4923 APTVDNGLNPAPADRLPGTPPPVSDPLSQPRSGSVQCNGQQPNTCVYTPS
*
MMAR_2887|M.marinum_M -IAAAEYDPTTGTYTGPDGRQYTRSDLAQTAPKDQTWQSMLLPPPVP
MUL_2865|M.ulcerans_Agy99 -IAAAEYDPATGTYTGPDGRQYTRSDLAQTAPKDQTWQSMLLPPPLP
Rv1971|M.tuberculosis_H37Rv ----------------------------------QTWQTMLLPPGS-
Mvan_3977|M.vanbaalenii_PYR-1 -LAAAEYDPATGSYIGPDGRSYTQADLAQGAPAGQTWQTMLLPPGS-
MSMEG_0351|M.smegmatis_MC2_155 -MAIARYDPATGTYLGPDGQVYTQADLADNGSKEQTWQSMLTPHGMN
Mflv_2106|M.gilvum_PYR-GCK -MAAAEYDPANGTYVGPDGRVYTQSNLAEGATEEQTWQTMLLPPKGN
MAV_2537|M.avium_104 -IAAVQYDPATGMYMGPDGRMYTQTDLAVGTKKGQTWQSMLMPPKRN
TH_3681|M.thermoresistible__bu -IAVTEYDPATGTYVGPDGRLYTQSNLVRSAFEVKTWESLMLPPGG-
MAB_4148c|M.abscessus_ATCC_199 PMAARAYDPKNGVFLDANNQPSVYAPALDRGTEAETWADLMLGPKPV
Mb0610|M.bovis_AF2122/97 TFPTTIYDVQSGKVVAPDGVVYSVEASTHAG--ADGWKVMLAPTG--
MLBr_02594|M.leprae_Br4923 GPPSAVYSPQSGELVGPDGVAYAVENSTKTG--DDGWKEMLAPAG--
. * ::