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M. thermoresistible (build 8) TH_1483 (-)

annotation: dehydrogenase
coordinates: 2802911 - 2804443
length: 511

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1483--100% (511)dehydrogenase
M. thermoresistible (build 8)TH_0076-3e-0852.63% (57) phytoene dehydrogenase
M. thermoresistible (build 8)TH_0785-1e-0664.29% (42) CONSERVED HYPOTHETICAL PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3754-1e-0539.47% (76) oxidoreductase
M. gilvum PYR-GCKMflv_1844-0.068.88% (511) amine oxidase
M. tuberculosis H37RvRv3727-1e-0539.47% (76) oxidoreductase
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_4806crtI2e-0926.77% (325) phytoene dehydrogenase CrtI
M. avium 104MAV_3890-0.068.12% (505) dehydrogenase
M. smegmatis MC2 155MSMEG_2344-0.067.98% (506) dehydrogenase
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_1580-0.070.80% (476) amine oxidase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1844|M.gilvum_PYR-GCK          ----MNDPRRVLHPAAAALPSASALGAQPKAAVIGGGIAGLAAATSLAER
Mvan_1580|M.vanbaalenii_PYR-1       ------------------------------MVVVGGGIAGLAAATGLAER
TH_1483|M.thermoresistible__bu      ----LTDPRRVHHHAPPGLPDARGLARRPHVVVVGAGIAGLAAATGLAER
MAV_3890|M.avium_104                MTAGATDRRRRILPAPTGLPDAGALPSRPRVAVVGGGIAGLTAATGLAER
MSMEG_2344|M.smegmatis_MC2_155      --------MQRTHTAPRGLPHAGELPRRPRVVVVGAGIAGLAAATGMAER
Mb3754|M.bovis_AF2122/97            ---------------------MKPSPADTHVVIAGAGIAGLAAAMILAEA
Rv3727|M.tuberculosis_H37Rv         ---------------------MKPSPADTHVVIAGAGIAGLAAAMILAEA
MMAR_4806|M.marinum_M               --------------------MRTIEGTADHVVVIGAGLAGLATALHLAGR
                                                                   .: *.*:***::*  :*  

Mflv_1844|M.gilvum_PYR-GCK          GVAVRLYERQSYLGGRVGGWQDTLDDGTT--VAMNRGFHAFFRQYYNLRG
Mvan_1580|M.vanbaalenii_PYR-1       GVAVEVIEKHGYLGGRVGGWSDTLADGTP--VAMNRGFHAFFRQYYNLRA
TH_1483|M.thermoresistible__bu      GVTVDVVEQAGYLGGRVGGWTEDIGPDVPGGAAMNRGFHAFFRQYYNLRT
MAV_3890|M.avium_104                GVAVEVIEREHYLGGRVGGWTEHHDGTDL---AMNRGFHAFFRQYYNLRA
MSMEG_2344|M.smegmatis_MC2_155      GVEVTVIERENYLGGRVGGWSEQHDGAEY---AMNRGFHAFFRQYYNLRA
Mb3754|M.bovis_AF2122/97            GVRVTLCEAASEAGGKAKSLRLADGHP------TEHSLRVYTDTYQTLLT
Rv3727|M.tuberculosis_H37Rv         GVRVTLCEAASEAGGKAKSLRLADGHP------TEHSLRVYTDTYQTLLT
MMAR_4806|M.marinum_M               GRSVTVVEREAWPGGRAGRLDIDGYRIDT-----GPTVLTMPDLIDEVFA
                                    *  * : *     **:.                    . .       :  

Mflv_1844|M.gilvum_PYR-GCK          ILSRI--DPSLSMLSPLTDYPLVDALGR------RDTFRGLPRTPPFNAM
Mvan_1580|M.vanbaalenii_PYR-1       LLRRS--DPGLSALTPVEDYPLIDGAGR------RDTFRGLPQTPPLNAL
TH_1483|M.thermoresistible__bu      LLRRI--DPGLGMLTPVDDYPLVDAHGR------RDTFRGLPKTPPFNAM
MAV_3890|M.avium_104                LLARL--DPRLRMLVPVNDYPLIDAAGR------RDSFRGLPRTPPLNAM
MSMEG_2344|M.smegmatis_MC2_155      LLARV--DPQLRMLTPVEDYPLIDGEGR------RESFRRLPHTPPWNAL
Mb3754|M.bovis_AF2122/97            LFSRIPTEHDRTMLDNLVGVSMVSATAQGVIGRIAAPVALQRRRPTFARI
Rv3727|M.tuberculosis_H37Rv         LFSRIPTEHDRTVLDNLVGVSMVSATAQGVIGRIAAPVALQRRRPTFARI
MMAR_4806|M.marinum_M               AVGET-ISDRLELLPVDPAYTAMFADGS--------SIDVHCDADRMVAA
                                     . .   .     *      . : . .         ..            

Mflv_1844|M.gilvum_PYR-GCK          AFALRSPTFRVRDLIRLDARAAAPLAAVSVPG------------------
Mvan_1580|M.vanbaalenii_PYR-1       AFALRSPTFRLRDLVRLDAKAAAPLAAVSVPE------------------
TH_1483|M.thermoresistible__bu      AFALRSPTFRLRDLIRLNARAAAPLAAVELPG------------------
MAV_3890|M.avium_104                AFAVRSPTFRLRDFARIDARAAAPLAAVSVPG------------------
MSMEG_2344|M.smegmatis_MC2_155      WFALRSPTFRLRDLMRLDAKAAAPLAAVSVPG------------------
Mb3754|M.bovis_AF2122/97            IGKVVEPPRQLVRILLRGPMVIVGLAQRGVPATDVLHYLYAHLRLLWMCR
Rv3727|M.tuberculosis_H37Rv         IGKVVEPPRQLVRILLRGPMVIVGLAQRGVPATDVLHYLYAHLRLLWMCR
MMAR_4806|M.marinum_M               IENFAGPE-QATGYLRLREWLTR-LYRIEFAG------------------
                                       .  *  :              *    ..                   

Mflv_1844|M.gilvum_PYR-GCK          --TYDELDDQDAESFLRDINFPDAARHLAFEVFSRSFFTRPAALSAAELA
Mvan_1580|M.vanbaalenii_PYR-1       --TYDLLDGRDAETFLRDINFPEAARHLAFEVFARSFFARPETLSAGELV
TH_1483|M.thermoresistible__bu      --IYRHLDDTDAESFLRAINFPPAARHLAFEVFSRSFFAQPSQLSAAELA
MAV_3890|M.avium_104                --TYRRLDHIDAATFLEDIRFPEAARHLAFEVFSRSFFADPAKLSAAELA
MSMEG_2344|M.smegmatis_MC2_155      --IYDRLDHIDAETFLKDINFPPAARHLAFEVFSRSFFADPSNLSAAELA
Mb3754|M.bovis_AF2122/97            ERLLAELGDISYADYLQ-LGCKSAQAQEFFSAVPRIYVAARTSAEAAAIA
Rv3727|M.tuberculosis_H37Rv         ERLLAELGDISYADYLQ-LGCKSAQAQEFFSAVPRIYVAARTSAEAAAIA
MMAR_4806|M.marinum_M               -FIGSNFDSPLSLLTPQLARLAAAGGFRNWDSMVKRHITDPRLRRVFTFQ
                                          :.        .      *     :. . : ..:      .  : 

Mflv_1844|M.gilvum_PYR-GCK          TMFHIYFLGSSEGLVFDVATSNF----------DVALWNPLASYLERLGA
Mvan_1580|M.vanbaalenii_PYR-1       TMFHIYFLGSSEGLIFDVANANF----------DVALWNPLRRYLEGRGV
TH_1483|M.thermoresistible__bu      TMFHIYFLGSSEGLVFDVVNANF----------DVALWNPLRDQLESRGV
MAV_3890|M.avium_104                TMFHIYFLGSAEGLIFDVPSANY----------DSALWQPLRSYLEQRHV
MSMEG_2344|M.smegmatis_MC2_155      TMFHIYFLGSSEGLVFDVPTSNY----------DTALWEPLRRYLHEHGV
Mb3754|M.bovis_AF2122/97            PIVLKGLFRLKSNCPSALNDAKLPAIMMMDGPTSERMVDPWIRHLTRLGV
Rv3727|M.tuberculosis_H37Rv         PIVLKGLFRLKSNCPSALNDAKLPAIMMMDGPTSERMVDPWIRHLTRLGV
MMAR_4806|M.marinum_M               SLYAGVAPQDALAAYAVIAYMDTISGVFFPRGGVRALPDALAAAAACAGV
                                    .:               :   .              : :.         .

Mflv_1844|M.gilvum_PYR-GCK          HVHTGTAVDSVTATS--QNSFIVTDGAGDENEVDGVVLATDVSALQSIVS
Mvan_1580|M.vanbaalenii_PYR-1       VFHTGAEVDSVTVA----DEVTVTGSRAQVWSADAAVLATDPGSLRRVVA
TH_1483|M.thermoresistible__bu      RFHTGVGVRAVDAG----ARFRVSCDSGDELTADGVVLATDVTGLQRIVA
MAV_3890|M.avium_104                RFRLGTSVGSID----AANRFAVHTDTDEELEVDAVVLATDVAGLQRIVA
MSMEG_2344|M.smegmatis_MC2_155      RFHLGASVTRIDPVTTSPDAFAVHTDSGERLDADAVVLAADIAGLQRIVA
Mb3754|M.bovis_AF2122/97            DIHFNTRVGDLEFDD--GRVTALISSDGRRFACDYALLAVPYLTLRELAK
Rv3727|M.tuberculosis_H37Rv         DIHFNTRVGDLEFDD--GRVTALISSDGRRFACDYALLAVPYLTLRELAK
MMAR_4806|M.marinum_M               QFHYGSQVSELERDD--ARITAVRTDRGERIACDAVVLTTELPTTYRLLG
                                     .: .  *  :           :  .       * .:*:.       :  

Mflv_1844|M.gilvum_PYR-GCK          SSESLGDPEWREKIHRMGTALPFVVQRLWLDRPVRGD---RPAFLGTGGL
Mvan_1580|M.vanbaalenii_PYR-1       ASPGLGDPSWRERVAAIGTAPPFVVLRLWLDRPVRHD---RAAFVGTGGR
TH_1483|M.thermoresistible__bu      ASPGLGDAGWRDRIAGLHTAPPFVVHRLWLDRPVAPD---RPPFLGTGGW
MAV_3890|M.avium_104                ASRGLANGEWRDRIAGLRTAPPFAVHRFWLDRPVSPR---RPAFLGTAGH
MSMEG_2344|M.smegmatis_MC2_155      SSPGLGDDRWRARVQGLRTAPPFAVHRLWLDRPVTAD---RPAFMGTAGH
Mb3754|M.bovis_AF2122/97            SAHVKRYLPQLTQQHALALEASNGIQCFLRDLPATWPPFIRPGVVTTHLQ
Rv3727|M.tuberculosis_H37Rv         SAHVKRYLPQLTQQHALALEASNGIQCFLRDLPATWPPFIRPGVVTTHLQ
MMAR_4806|M.marinum_M               RTP-RRLRRLRAAPSAVVVHAGCRSASTASEPAAHHTILFGQAWEQTFTD
                                     :              :             : ..            *   

Mflv_1844|M.gilvum_PYR-GCK          PPLDNISVLER---------------------------------------
Mvan_1580|M.vanbaalenii_PYR-1       DPLDNISVLER---------------------------------------
TH_1483|M.thermoresistible__bu      SPLDNVSVLET---------------------------------------
MAV_3890|M.avium_104                KPLDNISVLDR---------------------------------------
MSMEG_2344|M.smegmatis_MC2_155      KPLDNISVLER---------------------------------------
Mb3754|M.bovis_AF2122/97            SQWSLVCVLQGEGFWKNVRLPEGTRYVLSITWSDVETPGPVFDRPLSECT
Rv3727|M.tuberculosis_H37Rv         SQWSLVCVLQGEGFWKNVRLPEGTRYVLSITWSDVETPGPVFDRPLSECT
MMAR_4806|M.marinum_M               IIRDGRLMRDPS----------------------------------LLVT
                                       .   : :                                        

Mflv_1844|M.gilvum_PYR-GCK          YEHEARDWCARTGGSVVELHAYSVDQDSPELRRALISRLH-DLYPETVDA
Mvan_1580|M.vanbaalenii_PYR-1       YEREAAQWCSRTGGSVVELHAYSVRDEDADVRDRLIARMH-ELYPETATA
TH_1483|M.thermoresistible__bu      YEHQARDWARCTGGSVVELHSYAVTEPTDGLRDALLDRLH-ALYPETADA
MAV_3890|M.avium_104                YEREARAWAGAHHGSVVELHSYALDSAPSGA--AALRELR-RIYPETAAA
MSMEG_2344|M.smegmatis_MC2_155      YERQSAQWARDNGGSAVELHAYALDTAESGP--GALAQLH-RLYPETATA
Mb3754|M.bovis_AF2122/97            PDEILTECLTQCGLDKSNVLGWRIDHELKHLDEAEYEKVASELPPHLVSA
Rv3727|M.tuberculosis_H37Rv         PDEILTECLTQCGLDKSNVLGWRIDHELKHLDEAEYEKVASELPPHLVSA
MMAR_4806|M.marinum_M               RPTAGDPALAPPGRDLLYLLAPAPNLTAGRVDWGSAGGSYAQSMIDTVAS
                                                  .   : .                        . . :

Mflv_1844|M.gilvum_PYR-GCK          TIVGEKTLCRNDCPRLAPGDFAQRPTVRTPHPGLALAGDGIR---IDLPV
Mvan_1580|M.vanbaalenii_PYR-1       SIVAERLLRRDDCPRFAPGDFADRPTVSTPDPRLKLAGDGIR---IDLPV
TH_1483|M.thermoresistible__bu      GIVAERVLCRQDCPRFAPGDHAGRPGVAGPHPALALAGDGIR---IDLPV
MAV_3890|M.avium_104                QIVHETLLHRSDCPLFAPGGYPHRPTVVTPTPGLLLASDTVR---IDLPV
MSMEG_2344|M.smegmatis_MC2_155      EPVFERVLVRDDCPLFAPGSHADRPGVVTGVPGLVLAGDGIR---LDLPA
Mb3754|M.bovis_AF2122/97            PARGQRMVNFSPLTVLMPGARHRSPGICTSVPNLLLAGEVIYSPDLTLFV
Rv3727|M.tuberculosis_H37Rv         PARGQRMVNFSPLTVLMPGARHRSPGICTSVPNLLLAGEVIYSPDLTLFV
MMAR_4806|M.marinum_M               RLLPDLRDSVELLDVVTPLDWARQGMAAGTPFALAHTFGQTG----PFRP
                                        :     .    . *               *  :          :  

Mflv_1844|M.gilvum_PYR-GCK          ALMERAATTGIAAANSLLAHFGVTGHDMYT-----VPVRGRSPVLRHLAN
Mvan_1580|M.vanbaalenii_PYR-1       ALMERAATTGWTAANELLTGFGLAGHTLHT-----VPNRGRSAVLRRLAT
TH_1483|M.thermoresistible__bu      ALMERAATTGWSAANRLLTHFGLAGHPLYT-----VPTRGRSAALRRLAR
MAV_3890|M.avium_104                ALMERAATTGWSAANHLLKRWGLAGHPLVT-----VPTEGRSRLLRWLAN
MSMEG_2344|M.smegmatis_MC2_155      ALMERAATTGWAAANVLLNRWGVAGHALRS-----VPTAGRFAPLRWLAT
Mb3754|M.bovis_AF2122/97            PTMEKAACSGYLAARQIMNMVASHAAPLRIDFRDPAPFAVLRRVDRWFWS
Rv3727|M.tuberculosis_H37Rv         PTMEKAACSGYLAARQIMNMVASHAAPLRIDFRDPAPFAVLRRVDRWFWS
MMAR_4806|M.marinum_M               ANTVRGIDNAVLAGSSTVPGVGVPTTLISGRLAADRITGNTTRSIRHLDL
                                    .   :.  ..  *.   :   .     :                 * :  

Mflv_1844|M.gilvum_PYR-GCK          RVERRVLR------------------------
Mvan_1580|M.vanbaalenii_PYR-1       SAGG--VR------------------------
TH_1483|M.thermoresistible__bu      REVR-QVR------------------------
MAV_3890|M.avium_104                REGATRS-------------------------
MSMEG_2344|M.smegmatis_MC2_155      REERRAS-------------------------
Mb3754|M.bovis_AF2122/97            RRRRPPDRSTFATPPTAMPAPSHLTDVDRSAS
Rv3727|M.tuberculosis_H37Rv         RRRRPPDRSTFATPPTAMPAPSHLTDVDRSAS
MMAR_4806|M.marinum_M               KAQLS---------------------------