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M. thermoresistible (build 8) TH_0685 ()

annotation: PROBABLE FLAVIN-CONTAINING MONOAMINE OXIDASE AOFH (AMINE OXIDASE) (MAO)
coordinates: 1469717 - 1471078
length: 454

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0685-100% (454)PROBABLE FLAVIN-CONTAINING MONOAMINE OXIDASE AOFH (AMINE OXIDASE) (MAO)
M. thermoresistible (build 8)TH_2921-6e-8840.52% (459) PUTATIVE putative flavin-containing monoamine oxidase AofH_1
M. thermoresistible (build 8)TH_2567-4e-0641.38% (58) PUTATIVE -

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3195aofH1e-16865.77% (444) flavin-containing monoamine oxidase
M. gilvum PYR-GCKMflv_4501-0.071.78% (450) amine oxidase
M. tuberculosis H37RvRv3170aofH1e-16865.77% (444) flavin-containing monoamine oxidase
M. leprae Br4923MLBr_01044hemY2e-0642.86% (70) protoporphyrinogen oxidase
M. abscessus ATCC 19977MAB_2659-1e-11246.46% (452) putative flavin-containing monoamine oxidase AofH
M. marinum MMMAR_1389aofH1e-16864.94% (445) flavin-containing monoamine oxidase AofH (amine oxidase)
M. avium 104MAV_4062-1e-17267.64% (445) putative flavin-containing monoamine oxidase AofH
M. smegmatis MC2 155MSMEG_2035-0.071.94% (449) amine oxidase
M. ulcerans Agy99MUL_2487aofH1e-16464.04% (445) flavin-containing monoamine oxidase AofH (amine oxidase)
M. vanbaalenii PYR-1Mvan_1866-0.072.22% (450) amine oxidase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3195|M.bovis_AF2122/97            ------MTNPPWTVDVVVVGAGFAGLAAARELTRQG---HEVLVFEGRDR
Rv3170|M.tuberculosis_H37Rv         ------MTNPPWTVDVVVVGAGFAGLAAARELTRQG---HEVLVFEGRDR
MMAR_1389|M.marinum_M               ------MTNPSWIVDVVIVGAGFAGLAAARDLARQG---HDVLVLEGRDR
MUL_2487|M.ulcerans_Agy99           ------MTNPSWIVDVVIVGAGFAGLAAARDLARQG---HDVLVLEGRDR
MAV_4062|M.avium_104                ------MSGPPRIVDVVVVGAGFAGLAAARELNRQG---HDVVVFEGRDR
Mflv_4501|M.gilvum_PYR-GCK          ------------MAEVVVVGAGFAGLAAARELSRLG---RDVVVVEGRDR
Mvan_1866|M.vanbaalenii_PYR-1       ------------MADVVVVGAGFAGLSAARELTRLG---HEVVVVEGRDR
TH_0685|M.thermoresistible__bu      ------------VVDVVVVGAGFAGLTAARELTGLG---YEVVVFEGRDR
MSMEG_2035|M.smegmatis_MC2_155      -------MSIPTSADVVVVGAGFAGLTAARRLVQLG---YDVVVLEGRDR
MAB_2659|M.abscessus_ATCC_1997      MSRSVDNAVEAASVDVVIVGAGFAGLSAADRLVNMG---VSVLVIDARER
MLBr_01044|M.leprae_Br4923          ----------MTSRSYCVVGGGISGLTAAYRLRVATGDDVAITLFDPGDR
                                                  .  :**.*::**:**  *         : :.:  :*

Mb3195|M.bovis_AF2122/97            VGGRSLTGRVAGVPADMGGSFIGPTQDAVLALATELGIP-TTPTHRDGRN
Rv3170|M.tuberculosis_H37Rv         VGGRSLTGRVAGVPADMGGSFIGPTQDAVLALATELGIP-TTPTHRDGRN
MMAR_1389|M.marinum_M               VGGRSFTGSIAGLPADMGGSFVGPTQDAVLALAAELGVP-TVPTFHDGKN
MUL_2487|M.ulcerans_Agy99           VGGRSFTGSIAGLPADMGGSFVGPSQDAVLALAAELGVP-TVPTFHDGKN
MAV_4062|M.avium_104                VGGRSFTGSVAGLPADLGGTFVGPTQDAVLALAAELEVP-TTPTHHEGKN
Mflv_4501|M.gilvum_PYR-GCK          VGGRSYTGSVGGVPVDFGATFVGPTQDAVLALAAELGVE-SVPTYGEGKN
Mvan_1866|M.vanbaalenii_PYR-1       VGGRSYTGTIAGVPVDLGATFVGPTQDAVLKLADELGCE-REPTFGRGKN
TH_0685|M.thermoresistible__bu      VGGRSYTATLAGVPVDLGATFVGPGQTAVTGLAAELGCP-TVGTYHQGNN
MSMEG_2035|M.smegmatis_MC2_155      VGGRSSTATIAGVPVDLGGTFVGPTQDAVLGLAAELGCA-TVPTYNRGKN
MAB_2659|M.abscessus_ATCC_1997      VGGRSFTGEVAGVKVDLGATWVAKRHTAIRDLMDRLGCS-LTPQYDEGVN
MLBr_01044|M.leprae_Br4923          LGGVLRTECVGGQPMDLGAEAFLLRRPEVPALLAELGLSERQRATTDARP
                                    :**   *  :.*   *:*.  .   :  :  *  .*           .  

Mb3195|M.bovis_AF2122/97            VIQWRGSARSYRGTIPKLSLTGLIDIGRLR--WQFERIARGVPVAAPWDA
Rv3170|M.tuberculosis_H37Rv         VIQWRGSARSYRGTIPKLSLTGLIDIGRLR--WQFERIARGVPVAAPWDA
MMAR_1389|M.marinum_M               VIRWRGGVRPYSGTIPRLSLTGLLDIARLR--WQFERLARSIPISAPWAA
MUL_2487|M.ulcerans_Agy99           VIRWRGGVRPYSGTIPRLSLTGLLDIARLR--WQFERLARSIPISAPWAA
MAV_4062|M.avium_104                LIHWRGWTHAYHGTIPKLSLTGLLDIGRLR--WQFDRIARSIPLAAPWEA
Mflv_4501|M.gilvum_PYR-GCK          LIRWRGRVRSYRSTIPRLSILELLDVSRIQ--WRFDRISKRVPVDQPWAS
Mvan_1866|M.vanbaalenii_PYR-1       LIRWRGSVRSYRSTVPRLSIIELLDVSRIQ--WRFERVCRKVSVDQPWRS
TH_0685|M.thermoresistible__bu      LILWRGRLKSYRSTIPTLSILELLDVSRIQ--WRFERLCRQIPVGEPWRA
MSMEG_2035|M.smegmatis_MC2_155      LIRWHGRVRSYRSTIPRLSIIELLDVSRIQ--WRFERLFRHVDVAEPWNG
MAB_2659|M.abscessus_ATCC_1997      LLWMAGKRKTWTGTLPTVDPVDLEDLGRIT--IEMGKLLETINVDAAWKS
MLBr_01044|M.leprae_Br4923          LIYSQQRLHSLPPDTVAGIPSSATSVAGLVDDATVARIGAEAVRPLSWEP
                                    ::      :.              .:. :     . ::        .*  

Mb3195|M.bovis_AF2122/97            RRARELDDVSLGEWLRLVRATSSSRNLMAIMTR-----VTWGCEPDDVSM
Rv3170|M.tuberculosis_H37Rv         RRARELDDVSLGEWLRLVRATSSSRNLMAIMTR-----VTWGCEPDDVSM
MMAR_1389|M.marinum_M               NRAADLDGVSLRQWLRSVRASASSHDLMAIMTR-----VTWGCEPDDVSM
MUL_2487|M.ulcerans_Agy99           NRAADLDGVSLRQWLRSVRASASSHDLMAIMTR-----VTWECEPDDVSM
MAV_4062|M.avium_104                RRAAELDGLSLGGWLRSVRATASSHALLAMVAR-----VTWGCEPDEVSM
Mflv_4501|M.gilvum_PYR-GCK          PLAGQLDDISLDAWLRSVHAGASTRDLMAIMAR-----VTWGAEPGDVSM
Mvan_1866|M.vanbaalenii_PYR-1       PVAAELDAVSLDGWLRSVHAGASTRDLMAIVAR-----VTWGAEPDAVSM
TH_0685|M.thermoresistible__bu      PAAHRLDTMSLDRWLRSVYASASTRDLMAIMAR-----VTWGCEPHQVSM
MSMEG_2035|M.smegmatis_MC2_155      SLAHKLDQYSMERWLRYVHANASTRNLMAIMSR-----VTWGAEPDQVSM
MAB_2659|M.abscessus_ATCC_1997      PNADQLDSISFGEWLSQQQAVTSTNALMYIVTR-----VQWGCSPLDVSL
MLBr_01044|M.leprae_Br4923          GSDPAMAELVADRFGEQAVARLVDPLLGGVYAGSAATIGLRAGAPSVAAA
                                         :       :     *      *  : :            *  .: 

Mb3195|M.bovis_AF2122/97            LHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLG-----A
Rv3170|M.tuberculosis_H37Rv         LHAARYVRAAGGLDRLLDVKNGAQQDRVPGGTQQIAQAAAAQLG-----A
MMAR_1389|M.marinum_M               LHAARYVRAAGGLDRLLDVENGAQQELIPGGTQQIAELAAAELG-----T
MUL_2487|M.ulcerans_Agy99           LHAARSVRAAGGLDRLLDVENGAQQELIPGGTQQIAELAAAELG-----I
MAV_4062|M.avium_104                LHAARYAHAAGGLDRLLDVEDGAQQDRFPGGTQQIAAAAAAELG-----A
Mflv_4501|M.gilvum_PYR-GCK          LHAVRYVNAAGGLNRMLDVEGGAQQDRFPAGTQKIADLMAAELG-----D
Mvan_1866|M.vanbaalenii_PYR-1       LHAVRYVKAAGGLSRMLDVKGGAQQDRFLAGTQQIALRMAEQLG-----D
TH_0685|M.thermoresistible__bu      LHAARYVKAAGGLGRMLDVEGGAQQDRFPAGTQQIAQRMAEELDGAEPGS
MSMEG_2035|M.smegmatis_MC2_155      LHAVRYVKAAGGLTRLLDVEGGAQQDRLVEGTQQIALRMADELG-----Q
MAB_2659|M.abscessus_ATCC_1997      LHVLRYVQAVGGLDHMLAVEHGQQEYRVTETTQEIAKRLAAQIG-----D
MLBr_01044|M.leprae_Br4923          LDCGATSLMEAVRQGLPPVAAGPVFGALDGGYQVLIDELVRRSR------
                                    *.        .    :  *  *     .    * :    . .        

Mb3195|M.bovis_AF2122/97            RVLLNAAVRRIDRHGAG-VTVTS-DQGQAEAGFVIVAIPPAHRVAIEFDP
Rv3170|M.tuberculosis_H37Rv         RVLLNAAVRRIDRHGAG-VTVTS-DQGQAEAGFVIVAIPPAHRVAIEFDP
MMAR_1389|M.marinum_M               HVVLDAPVRRIDRHGAG-VTVTS-DQGQAEAGFVIVAIPPAHRAAIEFNP
MUL_2487|M.ulcerans_Agy99           HVVLDAPVRRIDRHGAG-VTVTS-DQGQAEAGFVIVAIPPAHRAAIEFNP
MAV_4062|M.avium_104                RVVLGAPVRRIERHGAG-VTVRT-DLGDTEAGFVIVAIPPAHRAAIEFAP
Mflv_4501|M.gilvum_PYR-GCK          RVVVGAPVRRITRNPDRTVTVTT-AGAEYQAGAVIVAVPPEHRSGIEFDP
Mvan_1866|M.vanbaalenii_PYR-1       RVVLGAPVRRIARHPDHSLTVGT-DRAEYTAAAVVVAIPPAHRGAVEFDP
TH_0685|M.thermoresistible__bu      RVRLGAPVRRITRNPDGTVTVHTGSGDGVTAGAVVVAVPPAHRDAIEFDP
MSMEG_2035|M.smegmatis_MC2_155      RIALDAPVQRIERHSGGDIGVTF-TTGHVRARAVVIAIAPQHRGDIEFDP
MAB_2659|M.abscessus_ATCC_1997      QIVLNTRVRQISQDDNG-VTVST-DSGVINAKYAIVTAAPEHRAYIEYQP
MLBr_01044|M.leprae_Br4923          LQWVAATVVGLDRGTCGWTLVDD-TGACWSADGVILAVPAPRLVRLLQQI
                                       : : *  : :       *         *  .::: .. :   :    

Mb3195|M.bovis_AF2122/97            PLPPEYQQLAHHWPQGRLSKAYAAYSTPFWRASGY---SGQALSDEAPVF
Rv3170|M.tuberculosis_H37Rv         PLPPEYQQLAHHWPQGRLSKAYAAYSTPFWRASGY---SGQALSDEAPVF
MMAR_1389|M.marinum_M               PLPTGYQELADNWPQGRLSKAYAAYSTPFWRINGF---TGQSLSDIGPVF
MUL_2487|M.ulcerans_Agy99           PLPTGYQELADNWPQGRLSKAYAAYSTPFWRINGF---TGQSLSDMGPVF
MAV_4062|M.avium_104                PLPAEYEQLARHWPQGRLSKAYAAYSTPFWRADGF---SGQALSDEGPVF
Mflv_4501|M.gilvum_PYR-GCK          PLPAEHRELSRHWPQGRLSKAYAAYETPFWRADGH---SGESLSDEGPVF
Mvan_1866|M.vanbaalenii_PYR-1       PLPADYGELNRHWPQGHLSKAYAAYQTPFWRTNGC---SGEALSDEGPVF
TH_0685|M.thermoresistible__bu      ALPPRHTALPGHWPQGMLSKAYAAYDTPFWRADGR---SGEALSDDGPVF
MSMEG_2035|M.smegmatis_MC2_155      PLPPEYTELAARWPQGRLSKAYAAYDRPFWRANGC---SGEALSDEGPVF
MAB_2659|M.abscessus_ATCC_1997      ALPAKIEGLTTSFPMGALSKAFVAYDKPFWRAEGL---SGEALTDTAPVF
MLBr_01044|M.leprae_Br4923          APRTVAAASRIVSASSAVVALSVPRDTTFPQNSGVLVASGERLRAKAVTL
                                    .  .         . . :    .. . .* : .*    :*: *   . .:

Mb3195|M.bovis_AF2122/97            ITFDVSPHADGPGILMGFVDA--RGFDSLPIEERRRDALRCFASLFGDEA
Rv3170|M.tuberculosis_H37Rv         ITFDVSPHADGPGILMGFVDA--RGFDSLPIEERRRDALRCFASLFGDEA
MMAR_1389|M.marinum_M               ITFDASPHDDGPGILMGFVDA--REFDSLSADQRRDRTLRCFASLFGDDA
MUL_2487|M.ulcerans_Agy99           ITFDASPHDDAPGILMGFVDA--REFDSLSADQRRDRTLRCFASLFGDDA
MAV_4062|M.avium_104                ITFDVSPHPDGPGILMGFVDA--RAFDSLPADQRRRDALRCFATLFGDDA
Mflv_4501|M.gilvum_PYR-GCK          ITFDCSPGDDGPGVLLGFTDP--RSFDPLPGEQRREIALAGFSALFGAAA
Mvan_1866|M.vanbaalenii_PYR-1       ITFDCSPGDGGPGVLLGFTDA--RTFDPLPPEQRREVALAGFTALFGEAA
TH_0685|M.thermoresistible__bu      ITFDVSPDENGPGILLGFTDA--RTFDPLSPDRRRDKALHGFAKLFGDAA
MSMEG_2035|M.smegmatis_MC2_155      ITFDVSPGDEGPGILLGFTDA--RTFDALPPEQRRQRALGGFATFFGDAA
MAB_2659|M.abscessus_ATCC_1997      ITFDVSPSDDGPGILMVFCTA--RVYDGFGPEVRRKLVLKQLVDLYGEQA
MLBr_01044|M.leprae_Br4923          SSRKWGLQGDTQLVRLSFGKFGDQVASTASDDELLAWAVSDLAAVF-DVT
                                     : . .       : : *     :  .    :     .:  :  .:   :

Mb3195|M.bovis_AF2122/97            LDPLDYVDYRWGTEEFAPGGPTAAVPPGSWTKYGHWLREPVGPIHWASTE
Rv3170|M.tuberculosis_H37Rv         LDPLDYVDYRWGTEEFAPGGPTAAVPPGSWTKYGHWLREPVGPIHWASTE
MMAR_1389|M.marinum_M               LEPLDYVDYCWGTEQFAPGGPTAAVPPGSWTRYGQLLRKPVGPIHWAGTE
MUL_2487|M.ulcerans_Agy99           LEPLDYADYCWGTEQFAPGGPTAAVPPGSWTRYGQLLRKPVGPIHWAGTE
MAV_4062|M.avium_104                LKPLDYVDHRWGAEEFAPGGPTAAVPPGSWTRFGRWLREPVGPIHWAGTE
Mflv_4501|M.gilvum_PYR-GCK          AHPIDYVDHCWGAEPFSPGGPTAAVPPGAWTAHGRWLRAPVDGIFWAGTE
Mvan_1866|M.vanbaalenii_PYR-1       SRPLDYLDHCWGAETFAPGGPTAAVPPGAWTAHGRWLRAPVDGIFWAGTE
TH_0685|M.thermoresistible__bu      LKPIDYLDFCWGCDDFAPGGPTAAVPPGSWTEFGPWLREPVDQIYWAGTE
MSMEG_2035|M.smegmatis_MC2_155      RDPIDYLDHCWGTEAFAPGGPTAAVPPEAWTAYGPWLRKPIDGIHWAGTE
MAB_2659|M.abscessus_ATCC_1997      NTPIDYIDHCWGTEPFAAGGPHPAAPPFASVNYGEALREPHGRIHWAGTE
MLBr_01044|M.leprae_Br4923          VDPVDVCVQRWIDAMPQYGPGHADLVAEVRAGLPPTLVVAGSHMDGIG--
                                      *:*     *       *   .   .   .     *  . . :   .  

Mb3195|M.bovis_AF2122/97            TADEWTGYFDGAVRSGQRAAAEVAALL--------
Rv3170|M.tuberculosis_H37Rv         TADEWTGYFDGAVRSGQRAAAEVAALL--------
MMAR_1389|M.marinum_M               TADEWTGYFDGAVRSGQRAAAEVAALL--------
MUL_2487|M.ulcerans_Agy99           TADEWTGYFDGAVRAGQRAAAEVAALL--------
MAV_4062|M.avium_104                TADEWTGFLDGAIRSGRRAAAEVTALL--------
Mflv_4501|M.gilvum_PYR-GCK          TADSWTGFLDGAVRSGLRAADEAHRELARA-----
Mvan_1866|M.vanbaalenii_PYR-1       TADRWTGFLDGAVRSGLRAATDVHQELTRRS----
TH_0685|M.thermoresistible__bu      TADQWTGFLDGAVRSGQRAAAEVHRRLSSGG----
MSMEG_2035|M.smegmatis_MC2_155      TADVWTGFLDGAVRSGQRAATEVAEALKSSAAAG-
MAB_2659|M.abscessus_ATCC_1997      TAGEWVGTMNGAILMGLHTADQIAQQLGVTGEVSK
MLBr_01044|M.leprae_Br4923          --------VPACISAAGRAIEALQAEVAR------
                                            . ..:  . ::       :