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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2854 | - | - | 100% (500) | putative AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_3645 | - | 5e-81 | 38.23% (497) | PUTATIVE AMP-dependent synthetase and ligase |
| M. thermoresistible (build 8) | TH_2679 | - | 4e-75 | 34.04% (520) | PUTATIVE acyl-CoA synthase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0566c | fadD8 | 1e-70 | 32.88% (514) | acyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_0027 | - | 1e-93 | 39.92% (506) | AMP-dependent synthetase and ligase |
| M. tuberculosis H37Rv | Rv0551c | fadD8 | 1e-70 | 32.88% (514) | acyl-CoA synthetase |
| M. leprae Br4923 | MLBr_02546 | fadD2 | 4e-54 | 31.53% (517) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_4626c | - | 2e-78 | 34.76% (515) | acyl-CoA synthetase |
| M. marinum M | MMAR_1606 | - | 7e-73 | 36.03% (494) | fatty-acid-CoA ligase |
| M. avium 104 | MAV_2610 | - | 3e-81 | 38.13% (514) | acyl-CoA synthase |
| M. smegmatis MC2 155 | MSMEG_5633 | - | 2e-76 | 38.18% (495) | feruloyl-CoA synthetase |
| M. ulcerans Agy99 | MUL_0650 | fadD8 | 2e-71 | 34.11% (516) | acyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_0943 | - | 1e-87 | 38.12% (501) | AMP-dependent synthetase and ligase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0566c|M.bovis_AF2122/97 MSTAGDDAVGVPPACGGRSDAVGVPQLARESGAMRDQDCSGELLRSPTHN
Rv0551c|M.tuberculosis_H37Rv MSTAGDDAVGVPPACGGRSDAVGVPQLARESGAMRDQDCSGELLRSPTHN
MUL_0650|M.ulcerans_Agy99 --------------------------------------MSDDLLRNPTHN
MAB_4626c|M.abscessus_ATCC_199 ------------------------------------MPDPFDPLHGSINS
Mflv_0027|M.gilvum_PYR-GCK ---------------------------------------------MFHNL
Mvan_0943|M.vanbaalenii_PYR-1 ---------------------------------------------MIHNL
MSMEG_5633|M.smegmatis_MC2_155 -----------------------------------------------MNL
TH_2854|M.thermoresistible__bu ------------------------------------------VSRSHLLI
MAV_2610|M.avium_104 -----------------------------------------------MLI
MMAR_1606|M.marinum_M ----------------------------------------------MTSL
MLBr_02546|M.leprae_Br4923 --MTKLRHYLERGAAEVHYLRSIFESGALGFEPPLTYAAMAVAMRKWGDL
Mb0566c|M.bovis_AF2122/97 GHLLVGALKRHQNKPVLFLGDT-RLTGGQLADRISQYIQAFEALGAGTGV
Rv0551c|M.tuberculosis_H37Rv GHLLVGALKRHQNKPVLFLGDT-RLTGGQLADRISQYIQAFEALGAGTGV
MUL_0650|M.ulcerans_Agy99 GHLLVGALERHKNRPVLFLGDT-TLTGGQLAERISQYIQAFEALGAGTGV
MAB_4626c|M.abscessus_ATCC_199 GHLLVSALKRNRDAPALVLGDV-TLTGAQMADEISKYIQAFIELVPDPTD
Mflv_0027|M.gilvum_PYR-GCK ADIVRSHGRNRPDAPALIVGDR-TVSYRELDERSNRTAQAFSRTGVGPGD
Mvan_0943|M.vanbaalenii_PYR-1 ADIIRVHGRERPGAPALVVGDR-TVTYGELDDRSSRAAQAFAQAGVGVGD
MSMEG_5633|M.smegmatis_MC2_155 FGLLDQTAARHGDRGAVFCGERELYTWTQLRDRAARLGSTLTEP----GT
TH_2854|M.thermoresistible__bu GDLITRAARTYGAAPALVHGDR-VMSFREFDDATNRLGNALLARGLRPGD
MAV_2610|M.avium_104 GDIATNNSRRYPDKRALVDADR-ALTWSQVDDRARRLAAFLIGRGLVPGD
MMAR_1606|M.marinum_M AGNLIEGARRHPNRIALRLDEI-EIPYGALDAASARLAGLLIQRGLRPGD
MLBr_02546|M.leprae_Br4923 AMLPAMPARRSPHRAALIDEEG-TLTYKELDRAAHALANGLIAKGVRGGD
.: : . . :
Mb0566c|M.bovis_AF2122/97 AVGLLSLNRPEVLMIIGAGQARGYRRTALHPLGSLADHAYVLNDAGISSL
Rv0551c|M.tuberculosis_H37Rv AVGLLSLNRPEVLMIIGAGQARGYRRTALHPLGSLADHAYVLNDAGISSL
MUL_0650|M.ulcerans_Agy99 TVGLLSLNRPEVLMILGASQARGYRRTALHPLGSLDDHAYVLYDAGASAL
MAB_4626c|M.abscessus_ATCC_199 GQGMLALNRPEVLLVIGAGQLLGTRRTALHPLGSLDDHAYVLADAKITTL
Mflv_0027|M.gilvum_PYR-GCK RVAFVERNGIEFFDVAFGSAKLGAVAVPVNWRLTAPEMRHVIADCGASVV
Mvan_0943|M.vanbaalenii_PYR-1 RVAFVDKNGAEFFEVTFGLAKVGAVGVPVNWRLAAPEMRHIIADSGAKIV
MSMEG_5633|M.smegmatis_MC2_155 RVAVASENRPEIIEIMFGVWAAECVYVPINYKLHPREMADILADSGAALV
TH_2854|M.thermoresistible__bu HVAVLAPNGIDGVVTYYALAKAGLVRVPLNSRETDFELAYKIDDSQARAL
MAV_2610|M.avium_104 RVMVIARNCIEWPEISFGLAKAGLITVPVNIRLAPDEVAHVRDDSGARAV
MMAR_1606|M.marinum_M RVGVMLPNVPYFAVAYYGVLRAGGVVVPMNVLLKERETSFYLTDSEAKAI
MLBr_02546|M.leprae_Br4923 GIAILARNHRWFVIANYGCARVGARIILLNSEFSGPQIKEVSEREGAKVI
. * . :: : :
Mb0566c|M.bovis_AF2122/97 IIDPNPMFVERALALLEQVDSLQQILTIGPVPDALKHVAVDLSAEAAKYQ
Rv0551c|M.tuberculosis_H37Rv IIDPNPMFVERALALLEQVDSLQQILTIGPVPDALKHVAVDLSAEAAKYQ
MUL_0650|M.ulcerans_Agy99 IIDPNPMFVERALGLLEKVDSLEQVLTIGPVPEALEDRAVDLSAEAAKYQ
MAB_4626c|M.abscessus_ATCC_199 VIDPTPQFVERAAALVAKVPTLTRVLTLGPVPAELAEVGQDLVAAAAGFA
Mflv_0027|M.gilvum_PYR-GCK VVG--QEFTGRIEAIADDLDVEVVVIGKHRHWPTFDDLLAAAPAVDPGVV
Mvan_0943|M.vanbaalenii_PYR-1 VVG--QDFAGHLEAIEDGLDADIVVIGDHPRWPAFDDWVASHPPVDPGVV
MSMEG_5633|M.smegmatis_MC2_155 FASP-----KIAPGLFEVTDVPVEVVGTDAYTQRFESEPVPAPLTDP---
TH_2854|M.thermoresistible__bu VTDG--RIPAETELVIHTEELAGMIAGADPGPCRIERD------------
MAV_2610|M.avium_104 IIHA-----DHLDKFLGELTELALILGVGAHSMLGTSELVTDYETALAQA
MMAR_1606|M.marinum_M IAWH--EFAPAAQAGADEAGAECILVKPGEFEELIQAAEPLEEAAVRE--
MLBr_02546|M.leprae_Br4923 IYDD-----EYTKVVSKAEPALGKLRALGVNPDEEEPPGSTDETLAELIA
. :
Mb0566c|M.bovis_AF2122/97 PQPLVAADLPPDQVIGLTYTGGTTGKPKGVIGTAQSIATMTSIQLAEWEW
Rv0551c|M.tuberculosis_H37Rv PQPLVAADLPPDQVIGLTYTGGTTGKPKGVIGTAQSIATMTSIQLAEWEW
MUL_0650|M.ulcerans_Agy99 PKPLVVADLPPNHIGGLTYTGGTTGKPKGVIGTAGNITAMTSIQLAEWEW
MAB_4626c|M.abscessus_ATCC_199 ARPLTPINLSPDHINGLTYTGGTTGKPKGVIGTSQSILTMTQIQLAEWEW
Mflv_0027|M.gilvum_PYR-GCK TG--------PDDLVFLMYTSGTTGAPKGVMLSNANVVCKTAGVGGPWKF
Mvan_0943|M.vanbaalenii_PYR-1 TG--------PDDVVLLMYTSGTTGAPKGVMLSNTNYVYKTGGVAGPWQF
MSMEG_5633|M.smegmatis_MC2_155 -----------AELAWLFYTSGTTGKSKGAMLSHRNLMAMTVAHLADFDA
TH_2854|M.thermoresistible__bu ----------PEDPLRLAYTGGTTGKPKAVVLTTRSELAEIANFLVDLLP
MAV_2610|M.avium_104 QPGAERRDITPDDVAFILYTSGTTGRAKGVMHTHRALLYQAADTNLVTEA
MMAR_1606|M.marinum_M ----------DDDTAVILYTSGTTGKPKGAELTHANLRRNVEVIVQMLQV
MLBr_02546|M.leprae_Br4923 RSSSAPAPKVRKRASIIILTSGTTGTPKGANRNTPASLAPLGGILSKVPF
: *.**** .*.. .
Mb0566c|M.bovis_AF2122/97 PANP-RFLMCTPLSHAG-AAFFTPTVIKGGEMIVLAK--FDPAEVLRIIE
Rv0551c|M.tuberculosis_H37Rv PANP-RFLMCTPLSHAG-AAFFTPTVIKGGEMIVLAK--FDPAEVLRIIE
MUL_0650|M.ulcerans_Agy99 PEHP-RFLMCTPLSHAG-AAFFTPTLVKGGEMIVLAK--FDPGEVLRVIE
MAB_4626c|M.abscessus_ATCC_199 PERP-KFLMCTPLSHAG-AAFFMPTLMKGGSMVVLPK--FDAGAVLAAIE
Mflv_0027|M.gilvum_PYR-GCK DADS-VSLAVMPLFHMAGFGWALAGLWEGAVTVVLRD--VDPGAILDAVA
Mvan_0943|M.vanbaalenii_PYR-1 DADA-VSLAVMPLFHMAGSGWALAGLWQGATTVVLRD--VEPAAILDAIA
MSMEG_5633|M.smegmatis_MC2_155 PDEF-CSLVHGAPMSHGSGLYIPPYVLRGARQVIPESGAFEPDEFLDLCD
TH_2854|M.thermoresistible__bu DLTPDSVMLHAAPITHGSGAFFLPHLVKGARNVILPR--FTPQGFVDAAV
MAV_2610|M.avium_104 NRSD-VMLATTPFFTAGGMVRTVSWLYLGQTMVIHQR--FDPQAVIDEIE
MMAR_1606|M.marinum_M GPDDVILGALPLFHAFGQTAGLNAAVAAGACLTLIPR--FSPEKALQIIE
MLBr_02546|M.leprae_Br4923 RAHEVTLLPAPMFHALG-YLHATLAMFLGSTLVLRRR--FKPATVLEDIE
. : * : . . :
Mb0566c|M.bovis_AF2122/97 EQRITATMLVPSMLYALLDHP--DSHTRDLSSLETVYYGASAINPVRLAE
Rv0551c|M.tuberculosis_H37Rv EQRITATMLVPSMLYALLDHP--DSHTRDLSSLETVYYGASAINPVRLAE
MUL_0650|M.ulcerans_Agy99 EQRITATMLVPSMLYALMDHP--DPHTRDLSSLETVYYGASAINPVRLAE
MAB_4626c|M.abscessus_ATCC_199 EHQITATMLVPSMIYALLDHP--DSRTRDLSSLQTVYYGASAINPVRLAE
Mflv_0027|M.gilvum_PYR-GCK RHRVTNMLLVPAVIQFLLDTT--GLDDTDLSRLRIVVYGASPITDDVLMR
Mvan_0943|M.vanbaalenii_PYR-1 RHRITNMLLVPAVIQFLLDTD--GVAEVDLSTLRVIVYGASPISDDVLVR
MSMEG_5633|M.smegmatis_MC2_155 HHPGCSAFLAPTMVQRLIQTG--RPRP---ANLRTVVYGGGPMYVDSLKK
TH_2854|M.thermoresistible__bu EHGATATFMVPTMIAMMLEDA--EIDR-DRLKLRRLCYGGAPIAPTLLAR
MAV_2610|M.avium_104 RSAITFTTFIPTMLHRTLAILE-DGPPRDMSSLRRISYGSAPVPPGLARK
MMAR_1606|M.marinum_M RDRVTVFEGVPTMFAAMLHST----ERPDTGSLRLCVSGGAAMPVEVMRG
MLBr_02546|M.leprae_Br4923 KHQATAMVVVPVMLSRILDTLENLETKSDLSSLRVVFVSGSQLGAELATR
. * :. : *. ... :
Mb0566c|M.bovis_AF2122/97 AIRRFGPIFAQYYGQSEAPMVITYLAKGDHDEK------RLTSCGRPTLF
Rv0551c|M.tuberculosis_H37Rv AIRRFGPIFAQYYGQSEAPMVITYLAKGDHDEK------RLTSCGRPTLF
MUL_0650|M.ulcerans_Agy99 AIDRFGPIFAQYYGQSEAPMVITYLPKADHDEK------RLTSCGRPTLF
MAB_4626c|M.abscessus_ATCC_199 AIERFGPIFAQYFGQSEAPMVISYLAKGDHDAK------RLSSCGRPSAF
Mflv_0027|M.gilvum_PYR-GCK GIDRFGGIFAQVYGMTESTGSVTQLDGDEHLPQ------LLRSCGRPYPW
Mvan_0943|M.vanbaalenii_PYR-1 GIERFGPIFAQVYGMTETTGSITQLDGPDHVPA------LLRSCGRPYPW
MSMEG_5633|M.smegmatis_MC2_155 ALAAYGQIFVQLYGQGEAPMTITGLRRDDHLDADD---ATLGSVGYPRSG
TH_2854|M.thermoresistible__bu GLETLGPVFVQLYGQAEAPLAITCLQPWEHTPE------RLTSAGKPYTF
MAV_2610|M.avium_104 AMDLLGCELQQRYGLTECGGQATILTPQDHRDIVAGKTSIATSCGQETPM
MMAR_1606|M.marinum_M FEQAFGTMVLEGYGLSETSPTASFNHPDRERKP--------GSIGTPIAG
MLBr_02546|M.leprae_Br4923 ALEELGPVIYNMYGSTEIAFATIAGPKDLQINS--------ATVGPVVKG
* . : :* * . : *
Mb0566c|M.bovis_AF2122/97 ARVALLDEHGKPVKQGEVGEICVSGPLLAGGYWNLPDETSRTFK-DGWLH
Rv0551c|M.tuberculosis_H37Rv ARVALLDEHGKPVKQGEVGEICVSGPLLAGGYWNLPDETSRTFK-DGWLH
MUL_0650|M.ulcerans_Agy99 ARVALLGEDGKPVPQGEPGEICVSGPLLAGGYWNKPDDTAQTFR-DGWLH
MAB_4626c|M.abscessus_ATCC_199 LRTALLDENDRPVKQGEPGEICVAGPLVAGGYWGLPEQTAETFK-NGWLR
Mflv_0027|M.gilvum_PYR-GCK VQIRVVDPTGRDVAPGTVGEVWTRSDQNMLGYWNNPEATAATLTPDGWLR
Mvan_0943|M.vanbaalenii_PYR-1 VQIRIVDETGADAVAGTVGEVWTRSEQNMLGYWNNPDATASTLTADGWLK
MSMEG_5633|M.smegmatis_MC2_155 VQVAVLRSDGTPADIGEIGEIVCRGDVVMSGYWNNPEATAATLK-DGWLH
TH_2854|M.thermoresistible__bu VEMDIRDEEDNSVPPGTPGEVVTRGPHTMSGYWRRPEATAETLGEDGWLR
MAV_2610|M.avium_104 CVIRVIDVDGNDAPPGDVGEIVITSPANAIGYWNRPEQTAETFR-PDGLR
MMAR_1606|M.marinum_M VQMKLLEVDTH-----GIGEIAIRGHNVMKGYWNRPDATAAAIDAEGWFR
MLBr_02546|M.leprae_Br4923 VKVKILDDSGKEVPRGQVGRIFVGNAFPFEGYTGG----GGKQIIDGLLS
: *.: . ** . . :
Mb0566c|M.bovis_AF2122/97 TGDLAREDSDGFYYIVDRVKDMIVTGGFNVFPREVEDVVAEHPAVAQVCV
Rv0551c|M.tuberculosis_H37Rv TGDLAREDSDGFYYIVDRVKDMIVTGGFNVFPREVEDVVAEHPAVAQVCV
MUL_0650|M.ulcerans_Agy99 TGDMAREDEDGFYFIVDRVKDMIVTGGFNVFPREVEDVVAEHSAVAQVCV
MAB_4626c|M.abscessus_ATCC_199 TGDVAREDEDGFWFIVDRTKDMIVTGGFNVFPREVEDVVAEHPSVAQVGV
Mflv_0027|M.gilvum_PYR-GCK TGDAGYLDRDGYLYLHDRIKDMIVSGAENVYPAEVENVLMTHPAVTDVAV
Mvan_0943|M.vanbaalenii_PYR-1 TGDAGYVDDDGYLFLHDRIKDMIVSGGENVYPVEVENVLMTHPAVADAAV
MSMEG_5633|M.smegmatis_MC2_155 TGDMGSFDARGHLTLRDRSKDVVISGGSNIYPREVEEVLLEHPDVVEAGV
TH_2854|M.thermoresistible__bu TGDIGQVDEEGYLYLLDRRNDVIISGGFNVYPREVEDALLTHPAVREAVV
MAV_2610|M.avium_104 SGDLGYLDEEGYLHITGRKTDLIISGGFNVYPAEIERVIAQHSDVDMVAV
MMAR_1606|M.marinum_M TGDLARIDEDGYYFIVDRSKDMIIRGGYNVYPREIEEVLYEHPEVREAAV
MLBr_02546|M.leprae_Br4923 SGDVGYFDEHDLLYISGRDDEMIVSGGENVFPAEVEDLISGHPEVVEATA
:** . * . : .* :::: *. *::* *:* : *. * . .
Mb0566c|M.bovis_AF2122/97 VGAPDEKWGEAVTAVVVLRSNAARDEPAIEAMTAEIQAAVKQRKGSVQAP
Rv0551c|M.tuberculosis_H37Rv VGAPDEKWGEAVTAVVVLRSNAARDEPAIEAMTAEIQAAVKQRKGSVQAP
MUL_0650|M.ulcerans_Agy99 VGAPDEKWGEAVTAVVVLRADAARDDAAIETMTAEIQAAVKQRKGSVQSP
MAB_4626c|M.abscessus_ATCC_199 IGVPDEKWGEAVTAIVVLRSDASSDEEAVALMTSEIQSAVKERKGSVQSP
Mflv_0027|M.gilvum_PYR-GCK IGIPDTRWGEAVKAVVVAG---------APVTEAELIAFAREQLAGFKLP
Mvan_0943|M.vanbaalenii_PYR-1 IGVPDRRWGEAVKAVVVAAR-------GAQLTEAELIAFARDRIGGFKLP
MSMEG_5633|M.smegmatis_MC2_155 VGAPDAEWGEIVVAFVVTNG--------TPVDAAALDAHLLERIARFKRP
TH_2854|M.thermoresistible__bu VGVDDERWGQRVSAAVVLR---------EEVDTQALIDHCAERLAGFKRP
MAV_2610|M.avium_104 VGVPDPEWGETPVAAVIAKSHVG----DQDALTAELAALCRAELAGYKQP
MMAR_1606|M.marinum_M VAVPDDMLGEEVGAAIALIPG-------ATSDAAALSDFVKERVAAYKYP
MLBr_02546|M.leprae_Br4923 IGVDDKEWGARLRAFVVKKQD-------ATIDEDAIKAYVRDHLARYKVP
:. * * * : : . . : *
Mb0566c|M.bovis_AF2122/97 KRVVVVDSLPLTGLGKPDKKAVRARFWEGAGRAVG------------
Rv0551c|M.tuberculosis_H37Rv KRVVVVDSLPLTGLGKPDKKAVRARFWEGAGRAVG------------
MUL_0650|M.ulcerans_Agy99 KQVVVVDSLPLTGLGKPDKKAVRARFWEGAGRAVG------------
MAB_4626c|M.abscessus_ATCC_199 KHVIIADSLPLTALGKLDKKALRQKYATV------------------
Mflv_0027|M.gilvum_PYR-GCK KSVDFVDALPRNPSGKLLKRQLREPYWTDEDRHIG------------
Mvan_0943|M.vanbaalenii_PYR-1 KSVDFVDVLPRNPSGKLLKRALREPYWDGADRHIG------------
MSMEG_5633|M.smegmatis_MC2_155 KRYEFIDALPKNSYGKVLKRELRERVTG-------------------
TH_2854|M.thermoresistible__bu RHIEVWDELPKSPVGKSLRRTVRETMRANEEVTAHA-----------
MAV_2610|M.avium_104 RRFVFWREFPLGPAGKILKREIANQVNHVSQSGGKMPVSTGSTEERR
MMAR_1606|M.marinum_M RRIWFVDELPKGPTGKILKRDITVPQASPAQQ---------------
MLBr_02546|M.leprae_Br4923 REVIFLEELPRNPTGKVLKRELRDFEVH-------------------
: . :* ** :: :