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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2800 | - | - | 100% (566) | putative monooxygenase, FAD-binding |
| M. thermoresistible (build 8) | TH_3923 | - | 9e-65 | 34.84% (597) | PUTATIVE putative monooxygenase, FAD-binding |
| M. thermoresistible (build 8) | TH_1880 | - | 5e-29 | 27.36% (552) | flavin-type hydroxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5009 | - | 9e-31 | 26.24% (564) | monooxygenase, FAD-binding |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4357c | - | 1e-170 | 55.56% (540) | putative monooxygenase |
| M. marinum M | MMAR_3384 | - | 3e-52 | 30.35% (537) | hydroxylase |
| M. avium 104 | MAV_2189 | - | 6e-57 | 32.30% (551) | FAD binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_4866 | mhpA | 3e-36 | 28.33% (600) | 3-(3-hydroxyphenyl)propionate hydroxylase |
| M. ulcerans Agy99 | MUL_4482 | - | 9e-09 | 24.93% (345) | hypothetical protein MUL_4482 |
| M. vanbaalenii PYR-1 | Mvan_4406 | - | 7e-64 | 30.17% (580) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2800|M.thermoresistible__bu --------------VSGPEQAPVLIVGAGPAGLATAYVLGRNGIPSVVCD
MAB_4357c|M.abscessus_ATCC_199 ---------------MSTVITPVVIVGAGPTGLATAYVLGRLGVRSIVCD
MAV_2189|M.avium_104 ----------------MTTRVPVLIVGAGVGGLSMSALLTQHGVRSLLVE
Mvan_4406|M.vanbaalenii_PYR-1 MPEFNDGIAETPLPDSAVIETDVLIVGSGPAGASAALFLSTLGIPNIMIT
MMAR_3384|M.marinum_M -----------MSNATLPAESDVLVVGAGPAGMVTAALLERLGMAVRILE
Mflv_5009|M.gilvum_PYR-GCK --------------MPGAHRSDVVVVGAGPTGLTLACCLRLHGVSVRVLD
MSMEG_4866|M.smegmatis_MC2_155 -------------MMNSPGAVDVVIVGAGPVGLTLANILGGQGVRTLIIE
MUL_4482|M.ulcerans_Agy99 ----------------MVGVQKVLISGASVAGLTTAYWLEQQGYSVTIVE
*:: *:. * : * * :
TH_2800|M.thermoresistible__bu QHSGIHPHPRAHVINTRSMELFRSWGIADAIARDEQAFDAGAGVRIVWKH
MAB_4357c|M.abscessus_ATCC_199 QYDGVNPHPRAHVVNTRSMELLRNWGIYDEIIADAIDFNR--GINVLWKH
MAV_2189|M.avium_104 KRREVFLYPKARNLSFRSLEILRGMGLGDEVHAVAEHVST-----VVAKP
Mvan_4406|M.vanbaalenii_PYR-1 KYRWTADTPRAHITNQRAMEIFRDMGIEDQVLADATRHALVG--DTVFCT
MMAR_3384|M.marinum_M RFPSRLALPKAHVVGPVTLDICVQAGLDVDRMS-ADAHPPEWDQFVRFAT
Mflv_5009|M.gilvum_PYR-GCK AAAGPATTSRANFLHARGSEVLDRMGALGTLPQESLRALR-------ITN
MSMEG_4866|M.smegmatis_MC2_155 ERETLIDYPRGVGLDDESLRTFQSIGLVDAILPHTVPNQILR--------
MUL_4482|M.ulcerans_Agy99 RHPGLRPGGQAIDVRGPALTVLDRMGILDAARDRKTGIRG---------A
:. *
TH_2800|M.thermoresistible__bu SVSGEELGCIDLLDAPVESIERRRAASPVGLISCPQDRIQRLMVDAVLRQ
MAB_4357c|M.abscessus_ATCC_199 TVAGEEFGRLDLADVPEAHLARRLNASPVTIGSCAQDRVQGRLLEAVRSS
MAV_2189|M.avium_104 ALNSPEE--RPALDVEGIFAGLERFSPEPAAQYCPQSRLEPILLAATRR-
Mvan_4406|M.vanbaalenii_PYR-1 SIAGEEIGRIHTWGTRPDREADYRLASPCELVDIPQTYLEPILVRNATS-
MMAR_3384|M.marinum_M RLFGEQLGTIAYEYQSPEWTARPRIN-------LSQPRFEAIVEGDVRQR
Mflv_5009|M.gilvum_PYR-GCK YLGDRPLATLEFGDPGMRTAAPPMVVS--------QAKVEAALRARLAD-
MSMEG_4866|M.smegmatis_MC2_155 -FYDANRRLLAEMAPPDARFGWPKRNG------FVQPMVDAELLAGLDRF
MUL_4482|M.ulcerans_Agy99 SVVDRDGNELSRDTESTPTGGPIDSPN------IELLRDDLIELLDGTIQ
. . :
TH_2800|M.thermoresistible__bu GMSRIDYDTRVVEITDAATGVEVTAE--SRGKPRRFRADYVVNAEGAGGR
MAB_4357c|M.abscessus_ATCC_199 GMTEVRYRTKVSAVGAHEDHVDVYLE--KDGHAETLRAEYVVDAEGAAAR
MAV_2189|M.avium_104 GGSDVRYGTELSSIDMDEAGVTAVVRDAESGTAETIRADYLIGADGVHSP
Mvan_4406|M.vanbaalenii_PYR-1 RGTQTRFSTEYVSHAQDTTGVDVQVRDRLTGNQYTIRAKYLIGADGARSK
MMAR_3384|M.marinum_M PGIEWVCGRWTGAQVDKGKVVSTATVD---DRQVQFSSRYLIGADGANSA
Mflv_5009|M.gilvum_PYR-GCK LDVEPEWGRKVIDVREDADGVVADLAD-----GARVRGQWLVGCDGTTSV
MSMEG_4866|M.smegmatis_MC2_155 DHVEVMWGRRMQTIAEDADGVTVEVSG--PDGPASVHAQYVVGCDGGRSA
MUL_4482|M.ulcerans_Agy99 STTEFIFDDSIATLQDDGAAVEVTFVR-----SGTRTFDFLIGADGLHSN
* . :::..:* .
TH_2800|M.thermoresistible__bu LRSALGIEMDGIPFIADQVT-SYFHADLSEWTGERPP-LLQWIIN----T
MAB_4357c|M.abscessus_ATCC_199 LRQSIGIDVEGIPEFGHQIN-MYFHADLSEWTDQESE-LLFWVLN----T
MAV_2189|M.avium_104 LRNLLGITTSGYGALPIYVVFVYFRAPWRKFIPHLHDGDGVQVKN----A
Mvan_4406|M.vanbaalenii_PYR-1 VAADIGLPFEGAMDIAGSMN-ITFKADIASHVAHRPSVLYWVIQPGANVG
MMAR_3384|M.marinum_M VRESLGISMHTYGQPSHQIN-AHVVADMREQLTDHPAVLYALVDP--EVA
Mflv_5009|M.gilvum_PYR-GCK VRRQTGIEFPGVR-----LSERFLLADIHLDWAVDRAGTTGWIHPDGVVG
MSMEG_4866|M.smegmatis_MC2_155 TRHLMGVSFDGTTS-----STRWVVIDLANDPLGHPNSEVGADPQ----R
MUL_4482|M.ulcerans_Agy99 VRRKV---FGPEEQFIKRLGTYAAIFTVPNFLELDYWQKWHYGDN-----
TH_2800|M.thermoresistible__bu DVQGTFIAMGQNRWTFTIGFGATD-EARRALDPQRCVELIRLAIGP--AG
MAB_4357c|M.abscessus_ATCC_199 GCPGVFIRLGGNRWTFHTGFDPAR-EAVSDYTPERCRELIRLAVG----A
MAV_2189|M.avium_104 DVDGIFLVAEGDLGMFITTYFPDEGETAEQFTPQRCRELLTKAIG-----
Mvan_4406|M.vanbaalenii_PYR-1 GIGAGLVRMVRPWNEWLIVWGYDINDEPPALDEDEAVNIVRQLLG----I
MMAR_3384|M.marinum_M GVAVIHGLGEPGHDNTIEWICGSPYDGENVPEMDTIVDRVRKVIG----S
Mflv_5009|M.gilvum_PYR-GCK AMPMPSTDGRDDLWRLFVYDPSLDRKPTDSEILDRISELVPYRTG----R
MSMEG_4866|M.smegmatis_MC2_155 PYASISIAHGIRRFEFMIHADETDEQAED---PEFVAELLRPFVP-----
MUL_4482|M.ulcerans_Agy99 TMAGVYSARDNSEARAALGFMDTELQIDYRDTEAQFAELERRMIEDGWVR
. :
TH_2800|M.thermoresistible__bu SDVDIDFRSAGSWTL---CATTARTYRAGRVFLVGDAAHQFPPTGGFGMN
MAB_4357c|M.abscessus_ATCC_199 PELEIDMRSVGTWVL---GASTARQYRKGRVFLVGDAAHQFPPTGGLGMN
MAV_2189|M.avium_104 EPLDIDVIEVAAWQP---YEQVADRFDCGRAFLVGDSAHTMPPFKAGGAN
Mvan_4406|M.vanbaalenii_PYR-1 SDLPVEITGASLWGN---NEMYATHLQQGRVFCAGDAVHRHPPSNGLGSN
MMAR_3384|M.marinum_M DDIGFEVLKLSPWVL---TARVADQFQAGPCFLIGDAAHRLPPTGGLGMN
Mflv_5009|M.gilvum_PYR-GCK RVKIGDAEWLSMFTV---HRRLADTYRRGRVLIAGDAAHVHAPFGGQGML
MSMEG_4866|M.smegmatis_MC2_155 HPDRVDVIRRRVYTH---HSRIAGSFRKGRMLLAGDAAHLMPVWQGQGYN
MUL_4482|M.ulcerans_Agy99 AQLLHYMRSAPDFYFDEMAQIVMDSWAKGRVALVGDAAYCCSPLSGQGTS
: * **:.: . . *
TH_2800|M.thermoresistible__bu TGLADADNLGWKLAAVLHGWADEELLDTYESERRPVALANSEFSVTNALK
MAB_4357c|M.abscessus_ATCC_199 TGLVDADNLGWKLAAVLQGWAHTQLLDTYESERRPVALANAESSIANVMK
MAV_2189|M.avium_104 TAIQSAHNLAWKLAAVLRGAAGPALLDTYHAERHPVGVFAARQSLT-GPS
Mvan_4406|M.vanbaalenii_PYR-1 TSIQDSYNLAWKIAAVLRGQADPALLETYSAERAPIAEQIVKRANKSSRE
MMAR_3384|M.marinum_M TAIQDGANLAWKLAAVIHGWAGEALLQSYSTERRPIAIANTLRSLENFEI
Mflv_5009|M.gilvum_PYR-GCK TGIGDAENVGFKLALVVRGLAADDLLDTYEAERRPLATQVLRGTSAITRV
MSMEG_4866|M.smegmatis_MC2_155 SGIRDAFNLGWKLAAVVRGQAGDALLDTYDAERRKHARAMIDLSTMVGRV
MUL_4482|M.ulcerans_Agy99 VAVLGAYILAGELAAAGN--DYQRGFANYHAEFS----------------
.: .. :. ::* . . : .* :*
TH_2800|M.thermoresistible__bu MASTGIGP--------TGPQFAAELESDDPSVAAAVRDRIRNAIPEQRPH
MAB_4357c|M.abscessus_ATCC_199 MADAGIGP--------NTMAVAAKLESDIPAVAAAERSRMAAAVPEQRPH
MAV_2189|M.avium_104 MALLRPGG--------KRPQLPADEEAP----------------------
Mvan_4406|M.vanbaalenii_PYR-1 YGQFFEVLGLLDANDEQEMAARIEERKAATPRGAAMREALVAAMELKNYE
MMAR_3384|M.marinum_M HIQALAEL--------ATAALDGTLHTMAAER-------LDNLVQQNSIG
Mflv_5009|M.gilvum_PYR-GCK NVAG-------------NPIVRFLRDRVAPRVFG---------LPAVQRW
MSMEG_4866|M.smegmatis_MC2_155 ISPT-------------NRKVAALRDKLIRGAS---------IVPTLKRY
MUL_4482|M.ulcerans_Agy99 --------------------------------------------------
TH_2800|M.thermoresistible__bu FDHLELEIGYVYPGDASDGDP--------------VSTPVVGGRLPHRWI
MAB_4357c|M.abscessus_ATCC_199 FDYLELELGYVYGGHNDAVDP--------------ITTAVMGGRMPHHWV
MAV_2189|M.avium_104 --IFALMIGYRYGANGIELVD--------------ELRAQPGTRVPHVWV
Mvan_4406|M.vanbaalenii_PYR-1 FNAHGVDLGQTYQSAAVVSEGSTLPIPARDPELFYEMSTVPGSHLPHAWV
MMAR_3384|M.marinum_M FNSPGLQLGYGYGPNQEVADATS-----------FTPSAAVGRRLPHAQV
Mflv_5009|M.gilvum_PYR-GCK TTYTASQLWVSYRNGPLGGRG---------------SKPRPGDRIDDAPC
MSMEG_4866|M.smegmatis_MC2_155 VLEMRFKPMPRYHEGAVYHAKPP------------TPASPVGTLFIQPRV
MUL_4482|M.ulcerans_Agy99 --------GFGERNQWLVTDN-----------------IPGGEPIPEEAF
* . .
TH_2800|M.thermoresistible__bu TRITPGQGTASTLDLLG-DGFTLLTGPAGAAWTAG----VRDVAVPVRTL
MAB_4357c|M.abscessus_ATCC_199 N---LGDRRISTLDLVG-VGFVLIAGPEGAEWIDAPK--IREMRIPLQVY
MAV_2189|M.avium_104 R------DGVSTLDLVG-PEFTVLTGDE------------RWCAAAASMS
Mvan_4406|M.vanbaalenii_PYR-1 G---DSRTKLALMDLAPYTEWTVITGIAGEAWAGAADKVGHELGIPLRTV
MMAR_3384|M.marinum_M KTG--AVDVVPIIDLVDRAGFTVFIQGAADPWREASG----GSEFPVTIV
Mflv_5009|M.gilvum_PYR-GCK S---RPDGTATRLHGELGGRWALLLPRG--------------VPAVGAAA
MSMEG_4866|M.smegmatis_MC2_155 DTR---EQDNVLLDDVLGTGFAVLCWNNNPRTLLGEAAFTRWKALGATFI
MUL_4482|M.ulcerans_Agy99 ER------IVNSLELEDYRQG-----------------------------
:.
TH_2800|M.thermoresistible__bu TAG----VDFAFTGPSDTTFLADD-------------GAVLVRPD-----
MAB_4357c|M.abscessus_ATCC_199 LVG----RDLEPIG-GAIPGAEGN-------------GAVLVRPD-----
MAV_2189|M.avium_104 LPA----HRVYNDQWAAITGLAPD-------------GALLIRPD-----
Mvan_4406|M.vanbaalenii_PYR-1 VIGPGREVTDLYYDWAKLREVDED-------------GALLVRPD-----
MMAR_3384|M.marinum_M DLAG----AVADQGWLELTGLAHEG------------AALVVRPD-----
Mflv_5009|M.gilvum_PYR-GCK VRG-----PAGYLADHVVTLHHDRD------------DVMLVRPD-----
MSMEG_4866|M.smegmatis_MC2_155 AARPSTQLHWTKDDDPDVVIVGDRTGALKAFFDAHTESVLVLRPDRCIAG
MUL_4482|M.ulcerans_Agy99 --------------------------------------------------
TH_2800|M.thermoresistible__bu GHIAWIATHLPADPAAELTSALRGVHLSADAARSASGQGASR--------
MAB_4357c|M.abscessus_ATCC_199 GHIAWIGTGLAVDPVEEISLAVETLCGKPLSEIAT---------------
MAV_2189|M.avium_104 DFVGWRADELPTDPQTALRQALSLCLGRAR--------------------
Mvan_4406|M.vanbaalenii_PYR-1 KHIAWRSMSMPDQPHAALRSAMAQILGRD---------------------
MMAR_3384|M.marinum_M GHIAAKAAGPQSWPGIHSSLRNHLQTGQPLGTEAIA--------------
Mflv_5009|M.gilvum_PYR-GCK AHLAWRGAHDDPTGLDRWLATALHPGGTQ---------------------
MSMEG_4866|M.smegmatis_MC2_155 ADIAQRAPELSTALFGILHLRQGGENGATGPVLYVPQPTAESSGTVGRAS
MUL_4482|M.ulcerans_Agy99 --------------------------------------------------