For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_2716 (-)

annotation: putative acyl-CoA dehydrogenase domain protein
coordinates: 3347574 - 3348626
length: 351

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2716--100% (351)putative acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)TH_3099-8e-3934.68% (346) PUTATIVE putative acyl-CoA dehydrogenase
M. thermoresistible (build 8)TH_0804-2e-3634.93% (375) acyl-CoA dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1968cfadE184e-3334.15% (325) acyl-CoA dehydrogenase FADE18
M. gilvum PYR-GCKMflv_0345-1e-3533.51% (373) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv1933cfadE184e-3334.15% (325) acyl-CoA dehydrogenase FADE18
M. leprae Br4923MLBr_00737fadE256e-1233.33% (108) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_3123-7e-3433.71% (356) putative acyl-CoA dehydrogenase
M. marinum MMMAR_2861fadE181e-3837.65% (324) acyl-CoA dehydrogenase FadE18
M. avium 104MAV_1267-4e-4136.54% (364) acyl-CoA dehydrogenase domain-containing protein
M. smegmatis MC2 155MSMEG_6585-2e-3634.07% (364) acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_2893fadE184e-3837.35% (324) acyl-CoA dehydrogenase FadE18
M. vanbaalenii PYR-1Mvan_0393-2e-3736.47% (329) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_2716|M.thermoresistible__bu      ----------------------------VTTDTTVSLAEIADTAAELAEL
MAV_1267|M.avium_104                -------------------------------------MNLELTDEQVALR
Mb1968c|M.bovis_AF2122/97           -------------------------------------MDFRYSTEQDDFR
Rv1933c|M.tuberculosis_H37Rv        -------------------------------------MDFRYSTEQDDFR
MMAR_2861|M.marinum_M               -------------------------------------MDFRYSTEQDDFR
MUL_2893|M.ulcerans_Agy99           -------------------------------------MDFRYSTEQDDFR
Mflv_0345|M.gilvum_PYR-GCK          --------------------------MAD-----TAG-EWVFSDEQNQLR
Mvan_0393|M.vanbaalenii_PYR-1       --------------------------MAD-----SQGAEYVFTEEQGQLR
MSMEG_6585|M.smegmatis_MC2_155      MAEELVDQPDKVAEELVDQPDKVAEELVDQPDKVAETTEFRFTDEQGQLR
MAB_3123|M.abscessus_ATCC_1997      ------MSASEDHQTRMSASEDNQTRMSASEDNQAQINEFEFTEEHGDLR
MLBr_00737|M.leprae_Br4923          ---------------------------MVGWSGNPLFDLFKLPEEHNELR
                                                                              .  .    

TH_2716|M.thermoresistible__bu      RQSALEIVRRAWSVERSRGLLDGPSPAFDDALWS-TVRDLGWPDVLVPES
MAV_1267|M.avium_104                DTTRRFLAEKAPIAHHVRRLLDDPT-GIEPAVWR-GLADLGCTGLLVPEQ
Mb1968c|M.bovis_AF2122/97           ASLRGFLGRGAP---VREMAAADGS---DRRLWQRLCTELELPALHVPPE
Rv1933c|M.tuberculosis_H37Rv        ASLRGFLGRGAP---VREMAAADGS---DRRLWQRLCTELELPALHVPPE
MMAR_2861|M.marinum_M               ESLRGFLRDQAPPARVRQVAAVGGH---DKKLWHRLCAELELPALHAPPE
MUL_2893|M.ulcerans_Agy99           ESLRGFLRDQAPPARVRQVAAVGGH---DKKLWHRLCAELELPALHAPPE
Mflv_0345|M.gilvum_PYR-GCK          AAVRAFCADHVDESSVRAAMESDPP--FDAKVWSRLGSELGVLGMAVPES
Mvan_0393|M.vanbaalenii_PYR-1       AAVRRFCADHIDETAVRAQMASEPR--FDPKVWARLGSELGVLGMSVPES
MSMEG_6585|M.smegmatis_MC2_155      AAVRKFGAEYFDEQTVRRLMESEPR--FDPAVWARLGAELGVLGLAVPEA
MAB_3123|M.abscessus_ATCC_1997      SLVRSWCERVWTPKHVRQIAEAG-S--VDLDAWRALGSELGVVGLSLPEQ
MLBr_00737|M.leprae_Br4923          ATIRALAEKEIAPHAADVDQRARFP-----EEALAALNASGFNAIHVPEE
                                                                                :  *  

TH_2716|M.thermoresistible__bu      AGGAGGTLRELAVLTEVTGSVVAPLPLAATAAAA----------------
MAV_1267|M.avium_104                HGGAGMTMVEAGIVAEELGAALYPGPWLSTAVAAPRALIRLCAGGDTAAG
Mb1968c|M.bovis_AF2122/97           HGGLGATLVETAIAFAELGRALTPIPFAATVFAIEAILR--MGDDEQRKR
Rv1933c|M.tuberculosis_H37Rv        HGGLGATLVETAIAFAELGRALTPIPFAATVFAIEAILR--MGDDEQRKR
MMAR_2861|M.marinum_M               YGGAGGTLVETAIAFGELGRALTPVPFAATILAIEAILR--MGDSEQRKG
MUL_2893|M.ulcerans_Agy99           YGGAGGTLVETAIAFGELGRALTPVPFAATILAIEAILR--MGDSEQRKG
Mflv_0345|M.gilvum_PYR-GCK          AGGAGGNLVDQAVAVEQLGAALACGPLFGTVYLAIPALVA-ASGG---QE
Mvan_0393|M.vanbaalenii_PYR-1       HGGAGGTLVDQAVAVEQLGAALACGPLFGTVYLAIPALVA-SSQP---GD
MSMEG_6585|M.smegmatis_MC2_155      DGGAGGTLVDQAVAVEELGAALACGPLIGTVYLSIPALVA-ASAGPVRDE
MAB_3123|M.abscessus_ATCC_1997      HGGGGLGVIELSIVAEELGRALACLPWISSAALGATALVS-SGDDSALAE
MLBr_00737|M.leprae_Br4923          YGGQGADSVAACIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKKQ
                                     ** *       :     . .    .   :                    

TH_2716|M.thermoresistible__bu      ----WCEGR--------PADGIAIVAPEPATAAGQTATGTFS----TVPY
MAV_1267|M.avium_104                LLRGIADGT--------THVAVCFLDTPPMAATREGETTVLHGQARAVPD
Mb1968c|M.bovis_AF2122/97           LLAGLLTGAR---IGTIAVSGHDVASATTVRAVRRDGRPALTGECTPVLH
Rv1933c|M.tuberculosis_H37Rv        LLAGLLTGAR---IGTIAVSGHDVASATTVRAVRRDGRPALTGECTPVLH
MMAR_2861|M.marinum_M               LLSGLLSGDR---IGALAAAGPDLS-VTSVRAGRRDGRPVLTGECAPVLH
MUL_2893|M.ulcerans_Agy99           LLSGLLSGDR---IGALAAAGPDLS-VTSVRAGRRDGRPVLTGECAPVLH
Mflv_0345|M.gilvum_PYR-GCK          LLGPLVDGTRTAAFAVRDDAGAFDASSVEVQAVPTEQGWALSGTVERVVD
Mvan_0393|M.vanbaalenii_PYR-1       LLAPLIEGIRTAAFAVPDAGGDFDADAVTVEAIPTDQGWTLTGTVQRVVD
MSMEG_6585|M.smegmatis_MC2_155      LLGALVEGARTAAFAVPDRAGAFDPALVGVTASADAT---LTGTVERIVD
MAB_3123|M.abscessus_ATCC_1997      WVPALAAGEKTITLAG---GRTRLADAITVSAESDTDGWKLTGDTEHVPD
MLBr_00737|M.leprae_Br4923          VLPSLAAEGAMASYALSEREAGSDAASMRTRAKADGDDWILNGFKCWITN
                                                                   *        :      :  

TH_2716|M.thermoresistible__bu      GAVATRLVVLAEAD------TAVLGVVDLTGPGVERTP----VTPLDHGP
MAV_1267|M.avium_104                AAAADVLLALAEDAG-----DTALFGVNTGSAGVAVRP----EHHIDPTH
Mb1968c|M.bovis_AF2122/97           GHVADLFVVPAVADG-----SIVLHVVAADAPGVTVTP----LPSFDITR
Rv1933c|M.tuberculosis_H37Rv        GHVADLFVVPAVADG-----SIVLHVVAADAPGVTVTP----LPSFDITR
MMAR_2861|M.marinum_M               GHVADLFVVPAESDG-----AVILYVVDAAAPGVAVVG----LPSFDITR
MUL_2893|M.ulcerans_Agy99           GHVADLFVVPAESDG-----AVILYVVDAAAPGVAVVG----LPSFDITR
Mflv_0345|M.gilvum_PYR-GCK          AGAADVLLVAATTPD-----GVGLFVVEADSLGVQRIR----LTTLDLTR
Mvan_0393|M.vanbaalenii_PYR-1       AGAADVVLVAAAGPD-----GLGLYAIEADNIGVQRIP----LTTLDLTR
MSMEG_6585|M.smegmatis_MC2_155      GAAADVFLVAATAPD-----GVALYAVDAS--DVQRTP----LTTLDLTR
MAB_3123|M.abscessus_ATCC_1997      GATADVILVLADTDS-----GPSLFAVDGDAPGVDRHS----LATLDMTR
MLBr_00737|M.leprae_Br4923          GGKSTWYTVMAVTDPDKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPT
                                    .  :    . *               :     ..            .   

TH_2716|M.thermoresistible__bu      -AAHISLDRAPLRQIARG-DDAIARHRDAVLRMRVAQVAELVGVAAAANE
MAV_1267|M.avium_104                KQSRVTFDAAPARRLATASADDVAAVVDDVL---IAACADALGAARAVMD
Mb1968c|M.bovis_AF2122/97           PVATLRLAGSPAEPLTAGTPDDMERVLDVAR---VLLAAEMLGGAEACLD
Rv1933c|M.tuberculosis_H37Rv        PVATLRLAGSPAEPLTAGTPDDMERVLDVAR---VLLAAEMLGGAEACLD
MMAR_2861|M.marinum_M               PVAKLRLVRAPAEALAASSADEVARLLDVAR---VLLAAEMLGGAEACLD
MUL_2893|M.ulcerans_Agy99           PVAKLRLVRAPAEALAASSADEVARLLDVAR---VLLAAEMLGGAEACLD
Mflv_0345|M.gilvum_PYR-GCK          PQATVGLLDAPAQ-LIAGPEEAERVITHALQVGAALLAVEQVGAAQHLLD
Mvan_0393|M.vanbaalenii_PYR-1       PQATVGLFHAPAR-LVAGPAEAERVITHALQIGAALLAVEQVGAAQHLLD
MSMEG_6585|M.smegmatis_MC2_155      PQATIALTDTPGR-LVSGPGEAERVIGHALQVGAALLAVEQVGAAQHLLD
MAB_3123|M.abscessus_ATCC_1997      RQANIHFNSAPAR-LIGAQGRGAEAVATALDVAATVLAAEQAGIAAHMLD
MLBr_00737|M.leprae_Br4923          TELYFDKCRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALD
                                        .     *   :                       .:  * *    :

TH_2716|M.thermoresistible__bu      AATEYAKVRVAFDRPIGSFQAIKHRLVDQRAAIEVGRALVNRAADACDHG
MAV_1267|M.avium_104                LAVEYAKTRTQFGQPIGSFQAVQHLCVDMYETVELARSGVIHALWVSDAP
Mb1968c|M.bovis_AF2122/97           LAVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAANG
Rv1933c|M.tuberculosis_H37Rv        LAVQYAGRRTQFDRPIGSFQAVKHACADMMIEIDATRATVMFAAMSAANG
MMAR_2861|M.marinum_M               LAIEYACSRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCAAGG
MUL_2893|M.ulcerans_Agy99           LAIEYACSRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCAAGG
Mflv_0345|M.gilvum_PYR-GCK          LSVDYAKNRLQFGRPIGSFQAVKHRLADDLVAVEHARSTAYHAVWALSDG
Mvan_0393|M.vanbaalenii_PYR-1       LTVDYAKNRLQFGRPIGSFQAVKHRLADDLVALEHARSTAYHAVWALTDG
MSMEG_6585|M.smegmatis_MC2_155      LSVDYAKSRLQFGRPIGSFQAVKHRLADDLVDLEHARSAAYHAVWALADG
MAB_3123|M.abscessus_ATCC_1997      VTTEYAKSRIQFGRIIGSFQAVKHRLADMAAATGNVRGAAYHAAWSHDHP
MLBr_00737|M.leprae_Br4923          AAIVYTKDRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERG
                                     :  *:  *  *.. *.:**:::.  .*        *  .  *       

TH_2716|M.thermoresistible__bu      QPDTEALVS-LAVFWAVDSLRTVPEGATQVFGGIAYTWEHDAHVYLRRTA
MAV_1267|M.avium_104                DGDERHLAA-LRAKAFAGRLAGVADTAIQVFGGIGYTWEHDAHLYLKRLL
Mb1968c|M.bovis_AF2122/97           D-ELQTVAP-LAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRRAK
Rv1933c|M.tuberculosis_H37Rv        D-ELQTVAP-LAKAQTAETFVLCAGSALQIHGAIAFTWEHDLHLYYRRAK
MMAR_2861|M.marinum_M               D-ELHATAP-LAKAQAADTYVLCAGSAIQVHGGIAFTWEHDLHLYFRRAK
MUL_2893|M.ulcerans_Agy99           D-ELHATAP-LAKAQAAGTYVLCAGSAIQVHGGIAFTWEHDLHLYFRRAK
Mflv_0345|M.gilvum_PYR-GCK          S-DDPALAVSIAQATTSAAFVRVATDTIQVHGGIGFTWEHQAHLYYKRAY
Mvan_0393|M.vanbaalenii_PYR-1       S-DDPALAVSIAQATCSEALVRVATDTIQVHGGIGFTWEHQAHLYYKRAY
MSMEG_6585|M.smegmatis_MC2_155      S-DDPALAASIAQATASAALTKIATDTIQVHGGIGFTWEHQAHLYFKRAT
MAB_3123|M.abscessus_ATCC_1997      SLDDPALATSIAQQVASAGAVEVTAKAIQSHGGIGFTWEHPAHLYYKRAV
MLBr_00737|M.leprae_Br4923          E-PDLGFISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAK
                                    .                      .  : * .*. .:* :.  . : :   

TH_2716|M.thermoresistible__bu      TLAATLGSRARHRRVVTDWLAARG-------------------
MAV_1267|M.avium_104                GYSAFLGGPDRYLTEVGARLAKRGSP-----------------
Mb1968c|M.bovis_AF2122/97           TTEALFGSSARNRALLAERAGLVKA------------------
Rv1933c|M.tuberculosis_H37Rv        TTEALFGSSARNRALLAERAGLVKA------------------
MMAR_2861|M.marinum_M               TTEALFGSSAHHRSLLADRVGL---------------------
MUL_2893|M.ulcerans_Agy99           TTEALFGSSAHHRSLLADRVGL---------------------
Mflv_0345|M.gilvum_PYR-GCK          TDAALLGGAEEHRARVADFVLVVAPEKD-----APRVATGMPS
Mvan_0393|M.vanbaalenii_PYR-1       TDAALLGSAEAHRARVAELVLDVAPRKD-----APRVATGMPS
MSMEG_6585|M.smegmatis_MC2_155      TDAALLGTAEAHRDRIAELILDRAVSDQATIDRAPRVATGTN-
MAB_3123|M.abscessus_ATCC_1997      SNSALFGGRAVHAERIAKEVIDA--------------------
MLBr_00737|M.leprae_Br4923          ITQIYEGTNQIQRVVMSRALLR---------------------
                                          *        :