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M. thermoresistible (build 8) TH_2587 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 617120 - 618313
length: 398

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2587 - - 100% (398) acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8) TH_3716 - e-158 69.27% (397) PUTATIVE putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_2739 - 2e-62 39.90% (396) PUTATIVE putative acyl-CoA dehydrogenase, middle domain protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3534 fadE26 9e-40 30.51% (413) acyl-CoA dehydrogenase FADE26
M. gilvum PYR-GCK Mflv_4100 - 1e-162 72.59% (394) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3504 fadE26 9e-40 30.51% (413) acyl-CoA dehydrogenase FADE26
M. leprae Br4923 MLBr_00737 fadE25 3e-18 23.60% (411) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0615 - 2e-47 34.58% (402) putative acyl-CoA dehydrogenase
M. marinum M MMAR_4010 - 1e-154 67.77% (391) acyl-CoA dehydrogenase
M. avium 104 MAV_5127 - 1e-159 68.88% (392) acyl-CoA dehydrogenase middle domain-containing protein
M. smegmatis MC2 155 MSMEG_0578 - 1e-159 70.78% (397) acyl-CoA dehydrogenase middle domain-containing protein
M. ulcerans Agy99 MUL_3874 - 1e-153 67.77% (391) acyl-CoA dehydrogenase
M. vanbaalenii PYR-1 Mvan_2246 - 1e-159 69.52% (397) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3534|M.bovis_AF2122/97            -------------MRISYTPQQEELRRELRSYFATLMTPERREALSSVQG
Rv3504|M.tuberculosis_H37Rv         -------------MRISYTPQQEELRRELRSYFATLMTPERREALSSVQG
MAB_0615|M.abscessus_ATCC_1997      -------------MLIDLTPEQAKLQNDLRHYFSNLVTAEETREMMIDR-
Mflv_4100|M.gilvum_PYR-GCK          MG------VAVDFSEVELCDADKAFRDEVREFLAAVVTDDVIRRDLESG-
Mvan_2246|M.vanbaalenii_PYR-1       MHGQEVGAVTMDFSEVELSDDDRAFQAELRGFLARVVTDDVIERDRRTG-
MSMEG_0578|M.smegmatis_MC2_155      ----------MDFSRVELSDEDTRFRDELRAFLAEIVTDEVIRRDRETG-
TH_2587|M.thermoresistible__bu      ----------MDFSTVELSPEDQRFRAELRDFLTRHVTAEVIRRDRETG-
MAV_5127|M.avium_104                ----------MDFSRVELSTQDAAFQESTRAFLAEHVTDEVRRRDRETG-
MMAR_4010|M.marinum_M               ----------MDFSRVQISDADREFRETARSFLATHVTEEVRRHDRETG-
MUL_3874|M.ulcerans_Agy99           ----------MDFSRVQISDADREFRETARSFLATHVTEEVRRHDRETG-
MLBr_00737|M.leprae_Br4923          ---MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRAR-
                                                   ..    .  ::   *      :: .          

Mb3534|M.bovis_AF2122/97            EYGVGNVYRETIAQMGRDGWLALGWPKEYGGQGRSAMDQLIFTDEAAIAG
Rv3504|M.tuberculosis_H37Rv         EYGVGNVYRETIAQMGRDGWLALGWPKEYGGQGRSAMDQLIFTDEAAIAG
MAB_0615|M.abscessus_ATCC_1997      ---HGSSYEAVVRRMGQDGWLGVGWPKEYGGHGFGPLEQQIFMNEVMRAD
Mflv_4100|M.gilvum_PYR-GCK          ----DNFDEQVHLALGSAGYLERDWRAEADG-GFTAVQRRIFELEIGRAH
Mvan_2246|M.vanbaalenii_PYR-1       ----DNFDETVHLALGAAGYLERDWRAGQDG-GFTAVQRRIFELEIGRAH
MSMEG_0578|M.smegmatis_MC2_155      ----ENFDESVHLALGGAGYLAADYRCADDG-GFSAVRRRIWELEIGRAH
TH_2587|M.thermoresistible__bu      ----DNFDEGVHTALGAAGYLEKDFRSEAEG-GWNALRRRIWELEIGRAH
MAV_5127|M.avium_104                ----ENFSEPVHVALGEAGYLESDWKLESEG-GFDPVRRRIFQLEIGRAH
MMAR_4010|M.marinum_M               ----DNFHEGLHLALGAAGYLAAEWKPEADG-GFSRVRRRIWELEKRRAH
MUL_3874|M.ulcerans_Agy99           ----DNFHEGLHLALGAAGYLAAEWKPEADG-GFSRVRRRIWELEKRRAH
MLBr_00737|M.leprae_Br4923          ------FPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD
                                            .     :.  *:          * *   :   *   *   . 

Mb3534|M.bovis_AF2122/97            AP-VPFLTINSVAPT-IMAYGTDEQKRFFLPRIAAGDLHFSIGYSEPGAG
Rv3504|M.tuberculosis_H37Rv         AP-VPFLTINSVAPT-IMAYGTDEQKRFFLPRIAAGDLHFSIGYSEPGAG
MAB_0615|M.abscessus_ATCC_1997      VP-MPLVTLQTVGPT-LQKYGTEEQKKKFLPGILAGEIHFAIGYTEPEAG
Mflv_4100|M.gilvum_PYR-GCK          TPWFHWPTTAMVANA-VDHFGSDELKDEVLPQVLAGRYRLCLGYTEPEGG
Mvan_2246|M.vanbaalenii_PYR-1       TPWFHWGTTSMVARA-LDQFGSDELKDEVLDRVLSGEFRLCLGYTEPDGG
MSMEG_0578|M.smegmatis_MC2_155      TPWFHWGTTAMAAHT-VEKFGTPELVEEVLPGVLSGRVRICLGYTEPEGG
TH_2587|M.thermoresistible__bu      TPWFHWGTTAMVAQS-VEKFGTPELRDEVIPGVLTGEIRLCLGYTEPEGG
MAV_5127|M.avium_104                TPWFHWGTTAVVARL-VKQFGAPELADAILPGVLSGKIRLCLGYTEPEGG
MMAR_4010|M.marinum_M               VPWVTWGTTAMVARS-VAKFGSPELVEEVLPGVFSGHVRMCLGYTEPEGG
MUL_3874|M.ulcerans_Agy99           VPWVTWGTTAMVARS-VAKFGSPELVEEVLPGVFSGHVRMCLGYTEPEGG
MLBr_00737|M.leprae_Br4923          ASASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAG
                                    ..     :    .   :   *: *    .:  : :     . . :*  .*

Mb3534|M.bovis_AF2122/97            TDLANLRTTAVRDGDD--YVVNGQKMWTSLIQYADYVWLAVRTNPESSGA
Rv3504|M.tuberculosis_H37Rv         TDLANLRTTAVRDGDD--YVVNGQKMWTSLIQYADYVWLAVRTNPESSGA
MAB_0615|M.abscessus_ATCC_1997      TDLASLRTTAVRDGDH--YVVNGQKIFTTGAHQAQYIWLACRTDP---SA
Mflv_4100|M.gilvum_PYR-GCK          SDIATCKTRAVREADGSTWIINGSKMFTSNAHHAQYVYLITNTDP---QA
Mvan_2246|M.vanbaalenii_PYR-1       SDVATCKTRAVRDGDG--WIVNGSKMFTSNAHHAQYVFLITNTDP---AA
MSMEG_0578|M.smegmatis_MC2_155      SDVATCKTRAVRDGDA--WIINGSKMFTSNAHNAQYVFLVTNTDP---EA
TH_2587|M.thermoresistible__bu      SDVATCRTRAVREADGSSWIINGAKMFTSNAHHAQYVFLLTNTDP---AA
MAV_5127|M.avium_104                SDVATCKTRAVRDGSG--WIINGSKMFTSNAQNAEYVFLLTNTDP---RR
MMAR_4010|M.marinum_M               SDVATCKTRALRDGDS--WLINGSKMFTTGAHNCQYVFLITNTDP---QA
MUL_3874|M.ulcerans_Agy99           SDVATCKTRALRDGDS--WLINGSKMFTTGAHNCQYVFLITNTDP---QA
MLBr_00737|M.leprae_Br4923          SDAASMRTRAKADGDD--WILNGFKCWITNGGKSTWYTVMAVTDP----D
                                    :* *. :* *  :..   :::** * : :    . :  :   *:*     

Mb3534|M.bovis_AF2122/97            KKHRGISVLIVPTTAEGFSWTPVHTMAGP---DTSATYYSDVRVPVANRV
Rv3504|M.tuberculosis_H37Rv         KKHRGISVLIVPTTAEGFSWTPVHTMAGP---DTSATYYSDVRVPVANRV
MAB_0615|M.abscessus_ATCC_1997      PKHKGISILIVDTKDPGYSWTPIITNDGAH--HTNATYYTDVRVPVEMLV
Mflv_4100|M.gilvum_PYR-GCK          PKHQSLTMFLVPLDSPGVEIQPIRTVDGD---RTNITFYSDVRVDDRYRI
Mvan_2246|M.vanbaalenii_PYR-1       PKHQSLTMFLVPLDATGVEIQPIRTVDGD---RTNITFYSDVRIDDRYRV
MSMEG_0578|M.smegmatis_MC2_155      PKHNSLTMFLVPLGTPGVEIQGIRTVDGD---RTNITYYSDVRVSDRYRV
TH_2587|M.thermoresistible__bu      PKHQSLTMFLVPLDTPGIEIGPIRTVDGD---RTNIVYYSDVRVDDHYRI
MAV_5127|M.avium_104                PKHKNLTMFLVPLDSPGIEIQGIRTVDGD---RTNIVYYSDVRVDDLYRI
MMAR_4010|M.marinum_M               RKHKSLTMFLVPLDSAGIEIQGIRTVDGD---RTNIVYYSDVRIDDKYRL
MUL_3874|M.ulcerans_Agy99           RKHKSLTMFLVPLDSAGIEIQGIRTVDGD---RTNIVYYSDVRIDDKYRL
MLBr_00737|M.leprae_Br4923          KGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRII
                                       ..:: ::*     * .     .  *     *.  :: . *:     :

Mb3534|M.bovis_AF2122/97            GEENAGWKLVTNQLNHERVALVSPAP--IFGCLREVREWAQNTKDAGGTR
Rv3504|M.tuberculosis_H37Rv         GEENAGWKLVTNQLNHERVALVSPAP--IFGCLREVREWAQNTKDAGGTR
MAB_0615|M.abscessus_ATCC_1997      GEENAGWKLITTQLNHERVSLGPSGR--IAGMYDRVYEWAS-KPGPDGVA
Mflv_4100|M.gilvum_PYR-GCK          GPVNGGWGVLREALNAEHGTVERDAS--GLQKIAVMTEHALLLAEEVDRV
Mvan_2246|M.vanbaalenii_PYR-1       GAVNGGWAVLREALNAEHGTVEHDDS--GLNKIAVMTEHATLLADEVDRI
MSMEG_0578|M.smegmatis_MC2_155      GDVNGGWGVLRGALDVEHGTFERDTH--GLQKIATMTEHITLMAEALDLV
TH_2587|M.thermoresistible__bu      GEVNGGWTVLREALNVEHGTVERDSQ--GLQKLATMTEHALLTAEGLDWA
MAV_5127|M.avium_104                GEVNGGWTVMRFALDAEHGITDPQDH--GLQNISMLSEHGHLMAEAADGV
MMAR_4010|M.marinum_M               GAVNGGWTVLREPLNVEHGAVAAAPD--GLQDTSIMMHQAGSMAEAVDRA
MUL_3874|M.ulcerans_Agy99           GAVNGGWTVLREPLNVEHGAVAAAPD--GLQDTSIMMHQAGSMAEAVDRA
MLBr_00737|M.leprae_Br4923          GEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESI
                                    *  . *:      *:  :                                

Mb3534|M.bovis_AF2122/97            LIDSEWVQLNLARVHAKAEVLKLINWELASSQSGPKDAGPSPADASAAKV
Rv3504|M.tuberculosis_H37Rv         LIDSEWVQLNLARVHAKAEVLKLINWELASSQSGPKDAGPSPADASAAKV
MAB_0615|M.abscessus_ATCC_1997      PLSHEDVRRVLGEMKAVWRLNELLNWQVASS-----GDDISMADAAATKI
Mflv_4100|M.gilvum_PYR-GCK          ASVVG-------DRLGDGEVAYRLGRSVARL------EAALSTPEMFGRV
Mvan_2246|M.vanbaalenii_PYR-1       AGEMYRS-----GRLDDDSIGYRLGRSIARL------EAALSTPEMFGRV
MSMEG_0578|M.smegmatis_MC2_155      AAQAP----------GDGASRFRLGRGIACT------EAAMSTPDMYGRV
TH_2587|M.thermoresistible__bu      VAVAASPGPDGRRLLDDESVQYRLGRSVARL------EAALSTPAEYGRV
MAV_5127|M.avium_104                AAILARPDAAGRRPIDDESVKYRLGRGMARI------EAAMSTPGMYGRV
MMAR_4010|M.marinum_M               ASCVMRPDPDGRRPIDDTSVAYRLGRSVARM------EAALSAPSIFGRV
MUL_3874|M.ulcerans_Agy99           ASCVMRPDPDGRRPIDDTSVAYRLGRSVARM------EAALSAPSIFGRV
MLBr_00737|M.leprae_Br4923          STFQSIQFMLADMAMKVEAARLIVYAAAARAE---RGEPDLGFISAASKC
                                                           :    *                   : 

Mb3534|M.bovis_AF2122/97            FGTELATEAYRLLMEVLGTAATLRQNSPGALLRGRVERMHRACLILTFGG
Rv3504|M.tuberculosis_H37Rv         FGTELATEAYRLLMEVLGTAATLRQNSPGALLRGRVERMHRACLILTFGG
MAB_0615|M.abscessus_ATCC_1997      LATEWIQKLGRLSEGVVGRYGDPADANTAETLE-WLDAQTKRHLVITFGG
Mflv_4100|M.gilvum_PYR-GCK          AIAQTLRDITPDLMDILGPASVLPSGRS-------AEYLFRLALPMGIYG
Mvan_2246|M.vanbaalenii_PYR-1       AIAQTLRDITPDLMDVLGTTSVVPEGLN-------AEYLFRLALPTGIYG
MSMEG_0578|M.smegmatis_MC2_155      AIAQTMRDVTPDLMDILGPAGALTDG---------VEYIFRLAGPTGIYG
TH_2587|M.thermoresistible__bu      AIAQMMRDITPELMDVLGAASALPVDTTGAAADGAVEYLFRLASPVAIYG
MAV_5127|M.avium_104                ALIQTMREVSQELMDLLGTASALPTDTPGSPDDGAIEFIFRHAVPAGIYG
MMAR_4010|M.marinum_M               AIAQTMRDISPDLMDILGSAAALPFGTDGAVDDGGAEYVYRFAPLVGIYG
MUL_3874|M.ulcerans_Agy99           AIAQTMRDISPDLMDILGSAAALPFGTDGAVDDGGAEYVYRFAPLVGIYG
MLBr_00737|M.leprae_Br4923          FASDIAMEVTTDAVQLFGGAGYTSDFP--------VERFMRDAKITQIYE
                                       :   .       :.*  .               :   :      :  

Mb3534|M.bovis_AF2122/97            GTNEVQRDIIGMVALGLPRANR--------
Rv3504|M.tuberculosis_H37Rv         GTNEVQRDIIGMVALGLPRANR--------
MAB_0615|M.abscessus_ATCC_1997      GVNEVMREMVSTAGLGTPRVPR--------
Mflv_4100|M.gilvum_PYR-GCK          GTLDVFRNMIAQHALGLGKPNYSPPR----
Mvan_2246|M.vanbaalenii_PYR-1       GTLDVFRNMIAQHALGLGRPNYSPPVQRP-
MSMEG_0578|M.smegmatis_MC2_155      GTLEVFRNMIAQHGLGLGKPNYAQPVKKVS
TH_2587|M.thermoresistible__bu      GTVEVFRNMIAQHALGLGKPSYGTPVKR--
MAV_5127|M.avium_104                GTMEVFRNMIAQHELGLGRPSYGR------
MMAR_4010|M.marinum_M               GTLEVFRNMIAQHVLGLGKPSYPHRT----
MUL_3874|M.ulcerans_Agy99           GTHEVFRNMIAQHVLGLGKPSYPHRT----
MLBr_00737|M.leprae_Br4923          GTNQIQRVVMSRALLR--------------
                                    *. :: * ::.   *

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2587	-	-	100% (398)	acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)	TH_3716	-	e-158	69.27% (397)	PUTATIVE putative acyl-CoA dehydrogenase
M. thermoresistible (build 8)	TH_2739	-	2e-62	39.90% (396)	PUTATIVE putative acyl-CoA dehydrogenase, middle domain protein