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DFSRVQISDADREFRETARSFLATHVTEEVRRHDRETGDNFHEGLHLALGAAGYLAAEWKPEADGGFSRV RRRIWELEKRRAHVPWVTWGTTAMVARSVAKFGSPELVEEVLPGVFSGHVRMCLGYTEPEGGSDVATCKT RALRDGDSWLINGSKMFTTGAHNCQYVFLITNTDPQARKHKSLTMFLVPLDSAGIEIQGIRTVDGDRTNI VYYSDVRIDDKYRLGAVNGGWTVLREPLNVEHGAVAAAPDGLQDTSIMMHQAGSMAEAVDRAASCVMRPD PDGRRPIDDTSVAYRLGRSVARMEAALSAPSIFGRVAIAQTMRDISPDLMDILGSAAALPFGTDGAVDDG GAEYVYRFAPLVGIYGGTLEVFRNMIAQHVLGLGKPSYPHRT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4010 | - | - | 100% (393) | acyl-CoA dehydrogenase |
| M. marinum M | MMAR_5030 | fadE29 | 5e-40 | 28.04% (403) | acyl-CoA dehydrogenase FadE29 |
| M. marinum M | MMAR_4992 | fadE26 | 9e-39 | 30.22% (407) | acyl-CoA dehydrogenase FadE26 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3534 | fadE26 | 4e-38 | 30.19% (414) | acyl-CoA dehydrogenase FADE26 |
| M. gilvum PYR-GCK | Mflv_4346 | - | 0.0 | 79.95% (389) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv3504 | fadE26 | 4e-38 | 30.19% (414) | acyl-CoA dehydrogenase FADE26 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 1e-15 | 22.22% (396) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0615 | - | 1e-42 | 29.78% (403) | putative acyl-CoA dehydrogenase |
| M. avium 104 | MAV_1595 | - | 0.0 | 83.80% (389) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2234 | - | 1e-173 | 76.61% (389) | acyl-CoA dehydrogenase middle domain-containing protein |
| M. thermoresistible (build 8) | TH_3716 | - | 0.0 | 82.26% (389) | PUTATIVE putative acyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_3874 | - | 0.0 | 99.75% (393) | acyl-CoA dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1998 | - | 0.0 | 79.18% (389) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3534|M.bovis_AF2122/97 ----------MRISYTPQQEELRRELRSYFATLMTPERREALSSVQGEYG
Rv3504|M.tuberculosis_H37Rv ----------MRISYTPQQEELRRELRSYFATLMTPERREALSSVQGEYG
MAB_0615|M.abscessus_ATCC_1997 ----------MLIDLTPEQAKLQNDLRHYFSNLVTAEETREMMIDR----
MMAR_4010|M.marinum_M -------MDFSRVQISDADREFRETARSFLATHVTEEVRRHDRETG----
MUL_3874|M.ulcerans_Agy99 -------MDFSRVQISDADREFRETARSFLATHVTEEVRRHDRETG----
MAV_1595|M.avium_104 -------MDFSRVTLSDEDQRFLDEAREFLRTHVTDEVRRRDRETG----
TH_3716|M.thermoresistible__bu -------MDFSRVELSDEDQAFYHEVRRFLREVVTDEVIQRDRETG----
Mflv_4346|M.gilvum_PYR-GCK -------MDFSRVQLSDDEQKFQDEVRTFLSEIVTDEVIRRDRETG----
Mvan_1998|M.vanbaalenii_PYR-1 -------MDFSRVELSDEDQKFLDEVRTFLGEIVTEDVIRRDRETG----
MSMEG_2234|M.smegmatis_MC2_155 -------MDFSHVELSSEDAAFREELRAFLAQIVTEDVIRRDRETG----
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRAR----
. . . : * :: .
Mb3534|M.bovis_AF2122/97 VGNVYRETIAQMGRDGWLALGWPKEYGGQGRSAMDQLIFTDEAAIAGAP-
Rv3504|M.tuberculosis_H37Rv VGNVYRETIAQMGRDGWLALGWPKEYGGQGRSAMDQLIFTDEAAIAGAP-
MAB_0615|M.abscessus_ATCC_1997 HGSSYEAVVRRMGQDGWLGVGWPKEYGGHGFGPLEQQIFMNEVMRADVP-
MMAR_4010|M.marinum_M -DNFHEGLHLALGAAGYLAAEWKPEADG-GFSRVRRRIWELEKRRAHVPW
MUL_3874|M.ulcerans_Agy99 -DNFHEGLHLALGAAGYLAAEWKPEADG-GFSRVRRRIWELEKRRAHVPW
MAV_1595|M.avium_104 -DNFDEGVHLALGAAGYLEREWKPEAEG-GFSRVQRRIWELEKRRAHVPW
TH_3716|M.thermoresistible__bu -DNFDEGVHLALGAAGYLEKEWKPADEG-GFSRVRRRIWELEKRRAHVPW
Mflv_4346|M.gilvum_PYR-GCK -DNFDEGVHLALGAAGYLDRDWNPATER-PFSRVERRIWELEKRRAHVPW
Mvan_1998|M.vanbaalenii_PYR-1 -DNFDEGVHLALGAAGYLERDWNPDSDR-AFTRVQRRIWELEKRRAHVPW
MSMEG_2234|M.smegmatis_MC2_155 -DNFDEGVHLALGQAGYLEREFKSEQDG-GFTRVQRRIWALERRRAEVPW
MLBr_00737|M.leprae_Br4923 ---FPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASA
. :. *: : * * . ..
Mb3534|M.bovis_AF2122/97 VPFLTINSVAPT-IMAYGTDEQKRFFLPRIAAGDLHFSIGYSEPGAGTDL
Rv3504|M.tuberculosis_H37Rv VPFLTINSVAPT-IMAYGTDEQKRFFLPRIAAGDLHFSIGYSEPGAGTDL
MAB_0615|M.abscessus_ATCC_1997 MPLVTLQTVGPT-LQKYGTEEQKKKFLPGILAGEIHFAIGYTEPEAGTDL
MMAR_4010|M.marinum_M VTWGTTAMVARS-VAKFGSPELVEEVLPGVFSGHVRMCLGYTEPEGGSDV
MUL_3874|M.ulcerans_Agy99 VTWGTTAMVARS-VAKFGSPELVEEVLPGVFSGHVRMCLGYTEPEGGSDV
MAV_1595|M.avium_104 VTWGTTAMVARS-VAKFGSEELQREVLPGVFSGHVRLCLGYTEPEGGSDV
TH_3716|M.thermoresistible__bu VTWGTSALVARS-VVRFGSPELQEEVMPGFFSGHVRMCLGYTEPEGGSDI
Mflv_4346|M.gilvum_PYR-GCK VTSGTTAMITKS-VEKFGSPELKDEVLPRVYSGHVRLCLGYTEPEGGSDV
Mvan_1998|M.vanbaalenii_PYR-1 VTSGTTAMIAKS-VERFGSPELKDEVMPKVYSGHVRLCLGYTEPEGGSDV
MSMEG_2234|M.smegmatis_MC2_155 VTWGTTIMIARS-VAKFASPEIRDDVLRGVFDGTVRMCLGYTEPEGGSDV
MLBr_00737|M.leprae_Br4923 SLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDA
: : : .: * .: . . . :* .*:*
Mb3534|M.bovis_AF2122/97 ANLRTTAVRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNPESSGAKKHRG
Rv3504|M.tuberculosis_H37Rv ANLRTTAVRDGDDYVVNGQKMWTSLIQYADYVWLAVRTNPESSGAKKHRG
MAB_0615|M.abscessus_ATCC_1997 ASLRTTAVRDGDHYVVNGQKIFTTGAHQAQYIWLACRTDP---SAPKHKG
MMAR_4010|M.marinum_M ATCKTRALRDGDSWLINGSKMFTTGAHNCQYVFLITNTDP---QARKHKS
MUL_3874|M.ulcerans_Agy99 ATCKTRALRDGDSWLINGSKMFTTGAHNCQYVFLITNTDP---QARKHKS
MAV_1595|M.avium_104 ATCKTRAVRDGNGWIINGSKMFTTGAHNCQYVFLITNTDP---DAPKHKS
TH_3716|M.thermoresistible__bu ATCKTRAVRDGDHWVINGSKMFTTGAHNCQYVFLITNTDP---DAPKHQS
Mflv_4346|M.gilvum_PYR-GCK ATCKTRAVRDGSSWVINGSKMFTTGAHNCQYVFLITNTDP---SAPKHKS
Mvan_1998|M.vanbaalenii_PYR-1 ATCKTRAVRDGDSWVINGSKMFTTGAHNCQYVFLITNTDP---SAPKHKS
MSMEG_2234|M.smegmatis_MC2_155 ATCKTRAVRDGDQWVINGSKMFTTGAHNCQYVFLITNTDP---DAPKHKS
MLBr_00737|M.leprae_Br4923 ASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDP----DKGANG
*. :* * **. :::** * : : . : : *:* ..
Mb3534|M.bovis_AF2122/97 ISVLIVPTTAEGFSWTPVHTMAGP---DTSATYYSDVRVPVANRVGEENA
Rv3504|M.tuberculosis_H37Rv ISVLIVPTTAEGFSWTPVHTMAGP---DTSATYYSDVRVPVANRVGEENA
MAB_0615|M.abscessus_ATCC_1997 ISILIVDTKDPGYSWTPIITNDGAH--HTNATYYTDVRVPVEMLVGEENA
MMAR_4010|M.marinum_M LTMFLVPLDSAGIEIQGIRTVDGD---RTNIVYYSDVRIDDKYRLGAVNG
MUL_3874|M.ulcerans_Agy99 LTMFLVPLDSAGIEIQGIRTVDGD---RTNIVYYSDVRIDDKYRLGAVNG
MAV_1595|M.avium_104 LTMFLVPLDSPGIDIQGIRTVDGD---RTNIVYYSDVRVDDKYRLGDVNA
TH_3716|M.thermoresistible__bu LTMFLVPLDTPGIEIQGIRTVDGD---RTNIVYYSDVRVPDKYRLGEVNG
Mflv_4346|M.gilvum_PYR-GCK LTMFLVPLDTPGVEIQGIRTVDGD---RTNIVYYSDVRVDDRYRLGEVNG
Mvan_1998|M.vanbaalenii_PYR-1 LTMFLVPLDSPGVEIQGIRTVDGD---RTNIVYYSDVRVDDRYRLGEVND
MSMEG_2234|M.smegmatis_MC2_155 LTMFLVPLDTPGIEIQGIRTVDGD---RTNIVYYSDVRVDDKYRLGEVNG
MLBr_00737|M.leprae_Br4923 ISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGT
:: ::* * . . * *. *: . *: :* .
Mb3534|M.bovis_AF2122/97 GWKLVTNQLNHERVALVSPAPIFGCLREVREWAQNTKDAG-GTRLIDSEW
Rv3504|M.tuberculosis_H37Rv GWKLVTNQLNHERVALVSPAPIFGCLREVREWAQNTKDAG-GTRLIDSEW
MAB_0615|M.abscessus_ATCC_1997 GWKLITTQLNHERVSLGPSGRIAGMYDRVYEWAS-KPGPD-GVAPLSHED
MMAR_4010|M.marinum_M GWTVLREPLNVEHGAVAAAPDGLQDTSIMMHQAGSMAEAV-DRAASCVMR
MUL_3874|M.ulcerans_Agy99 GWTVLREPLNVEHGAVAAAPDGLQDTSIMMHQAGSMAEAV-DRAASCVMR
MAV_1595|M.avium_104 GWTVLREPLNVEHGAVAAAPDGLQDVSIMMHQAGFMADAL-DKVAAKVTL
TH_3716|M.thermoresistible__bu GWQVLREPLNAEHGAVAAAPDGLQDVSIMNHQAGFLATAV-DRAAAAVNR
Mflv_4346|M.gilvum_PYR-GCK GWTVVREPLNAEHGDVAAADDGLADVSIMMHQAMFMAKAV-DTAAQKSTI
Mvan_1998|M.vanbaalenii_PYR-1 GWTVVREPLNAEHGAVDAADDGLQDVSIMMHQAMFMAAAV-DKAAQKSTI
MSMEG_2234|M.smegmatis_MC2_155 GWSVVREPLDAEHGAVAAAHDGLDDVAIMTHQATFMAHAA-DNVAALVGT
MLBr_00737|M.leprae_Br4923 GFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQS
*: *: : : . . .
Mb3534|M.bovis_AF2122/97 VQLNLARVHAKAEVLKLINWELASSQSGPKDAGPSPADASAAKVFGTELA
Rv3504|M.tuberculosis_H37Rv VQLNLARVHAKAEVLKLINWELASSQSGPKDAGPSPADASAAKVFGTELA
MAB_0615|M.abscessus_ATCC_1997 VRRVLGEMKAVWRLNELLNWQVASS-----GDDISMADAAATKILATEWI
MMAR_4010|M.marinum_M PDPDGRRPIDDTSVAYRLGRSVARM------EAALSAPSIFGRVAIAQTM
MUL_3874|M.ulcerans_Agy99 PDPDGRRPIDDTSVAYRLGRSVARM------EAALSAPSIFGRVAIAQTM
MAV_1595|M.avium_104 PDPHGRRLIDDSAIAYRLGRNAARM------EAALSAPSIYGRVALAQTM
TH_3716|M.thermoresistible__bu ADSSGRRLIDDGSVAYRLGRSVARL------EMALSTPSIFGRVAVAQTM
Mflv_4346|M.gilvum_PYR-GCK PDPNGRRLIDDGAVAYRLGRSVARL------EASLSAPSIFGRVALAQTM
Mvan_1998|M.vanbaalenii_PYR-1 PDPNGRRLIDDGSVAYRLGRSVARL------EASLSAPSIFGRVALAQTM
MSMEG_2234|M.smegmatis_MC2_155 RDAAGRAAVDDGSVAYRLGRSFARL------EASLSTPSIFGRVAMAQTM
MLBr_00737|M.leprae_Br4923 IQFMLADMAMKVEAARLIVYAAAARAE--RGEPDLGFISAASKCFASDIA
: * : : ::
Mb3534|M.bovis_AF2122/97 TEAYRLLMEVLGTAATLRQNSPGALLRGRVERMHRACLILTFGGGTNEVQ
Rv3504|M.tuberculosis_H37Rv TEAYRLLMEVLGTAATLRQNSPGALLRGRVERMHRACLILTFGGGTNEVQ
MAB_0615|M.abscessus_ATCC_1997 QKLGRLSEGVVGRYGDPADANTAETLE-WLDAQTKRHLVITFGGGVNEVM
MMAR_4010|M.marinum_M RDISPDLMDILGSAAALPFGTDGAVDDGGAEYVYRFAPLVGIYGGTLEVF
MUL_3874|M.ulcerans_Agy99 RDISPDLMDILGSAAALPFGTDGAVDDGGAEYVYRFAPLVGIYGGTHEVF
MAV_1595|M.avium_104 RDISPDLMDILGTASALPVGTDGAADDGASEYVFRFAPLVGIYGGTLEVF
TH_3716|M.thermoresistible__bu RDISPDLMDILGAASALPVGADGAADDGAAEYVYRFAPLVGIYGGTLEVF
Mflv_4346|M.gilvum_PYR-GCK RDISPDLMDILGTASALPVGTDGAADDGAAEYVYRFAPLVGIYGGTLEVF
Mvan_1998|M.vanbaalenii_PYR-1 RDISPDLMDVMGAASALPVGTDGAADDGASEYIYRFAPLVGIYGGTLEVF
MSMEG_2234|M.smegmatis_MC2_155 RDISPDFMDIAGSVSALPMGADGGADD-RSEYIYRFAPLVGIYGGTLEVF
MLBr_00737|M.leprae_Br4923 MEVTTDAVQLFG--------GAGYTSDFPVERFMRDAKITQIYEGTNQIQ
. : * . : : : : *. ::
Mb3534|M.bovis_AF2122/97 RDIIGMVALGLPRANR--------
Rv3504|M.tuberculosis_H37Rv RDIIGMVALGLPRANR--------
MAB_0615|M.abscessus_ATCC_1997 REMVSTAGLGTPRVPR--------
MMAR_4010|M.marinum_M RNMIAQHVLGLGKPSYP---HRT-
MUL_3874|M.ulcerans_Agy99 RNMIAQHVLGLGKPSYP---HRT-
MAV_1595|M.avium_104 RNMIAQYMLGLGKPAYAPVAQRAS
TH_3716|M.thermoresistible__bu RNMIAQYVLGLGKPSYGQPVKKSA
Mflv_4346|M.gilvum_PYR-GCK RNMIAQYVLGLGKPNYSPPRKAS-
Mvan_1998|M.vanbaalenii_PYR-1 RNMIAQYALGLGKPNYSPVKT---
MSMEG_2234|M.smegmatis_MC2_155 RNMIAQHVLGLGKPNYSPPKARAS
MLBr_00737|M.leprae_Br4923 RVVMSRALLR--------------
* ::. *