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M. thermoresistible (build 8) TH_2562 (-)

annotation: Alpha/beta hydrolase fold-3 domain protein
coordinates: 631067 - 632026
length: 320

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2562--100% (320)Alpha/beta hydrolase fold-3 domain protein
M. thermoresistible (build 8)TH_2573-2e-3940.94% (254) PUTATIVE Alpha/beta hydrolase fold-3 domain protein
M. thermoresistible (build 8)TH_2802-2e-3742.44% (238) PUTATIVE esterase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0223clipW5e-4543.09% (246) esterase LipW
M. gilvum PYR-GCKMflv_4102-1e-10159.02% (305) alpha/beta hydrolase domain-containing protein
M. tuberculosis H37RvRv0217clipW5e-4543.09% (246) esterase LipW
M. leprae Br4923MLBr_00314-4e-1732.34% (235) putative esterase
M. abscessus ATCC 19977MAB_2814-4e-4342.37% (236) lipase LipH
M. marinum MMMAR_0404lipW5e-9857.74% (310) esterase LipW
M. avium 104MAV_5118-2e-9759.22% (309) alpha/beta hydrolase domain-containing protein
M. smegmatis MC2 155MSMEG_2568-1e-10764.33% (300) LipW protein
M. ulcerans Agy99MUL_1054lipW9e-9159.12% (274) esterase LipW
M. vanbaalenii PYR-1Mvan_2244-1e-10461.59% (302) alpha/beta hydrolase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0223c|M.bovis_AF2122/97           --------MSGNEVHPDLRRIAVVTPRQLVGPRTLPVMRALIVVAGLRMS
Rv0217c|M.tuberculosis_H37Rv        --------MSGNEVHPDLRRIAVVTPRQLVGPRTLPVMRALIVVAGLRMS
Mflv_4102|M.gilvum_PYR-GCK          ---MT--RDIAERLDPQLR--HLAAARTDLSPPVLGAVRDSLNQRRA-ET
Mvan_2244|M.vanbaalenii_PYR-1       ---MTD-RDITERLDPALR--HLAGARTDLSPPVLGAVRDSLNQRRA-ET
MSMEG_2568|M.smegmatis_MC2_155      ---MAHRSGWTERLDPALR--EFAGARTDLSPETLAVVRASIDRRRR-ES
TH_2562|M.thermoresistible__bu      ----VNPPEAGQRLAPELR--HLWGTRTDLTADLLPTVRAVLDDRRR-AT
MMAR_0404|M.marinum_M               ----MTQPEAVDRLDPLLR--AVATARIDFTAESILTIRESMNQRRREAA
MUL_1054|M.ulcerans_Agy99           -----------------------------------------MNQRRREAA
MAV_5118|M.avium_104                ----MTALDGAERLDPALR--AVATTRTDFSPAAIELTRAPFNERRR-LA
MAB_2814|M.abscessus_ATCC_1997      -------MTATAGIDPIIVKILEAVPIQLVSPDGPQASRDAY---RAIAT
MLBr_00314|M.leprae_Br4923          MAISAGAPVEIVESGPSIAARLASLTSRLTIRPILAVGSYVPQLPWPFGL
                                                                                      

Mb0223c|M.bovis_AF2122/97           RTPPDIEVLTLESG---------VGVRLYRPA---GSNEPAPALLWIHAG
Rv0217c|M.tuberculosis_H37Rv        RTPPDIEVLTLESG---------VGVRLYRPA---GSNEPAPALLWIHAG
Mflv_4102|M.gilvum_PYR-GCK          ARTADLIGVEVEQREVPVPAGHTVTVRIYR-----GGPPQSPAVIYCHSG
Mvan_2244|M.vanbaalenii_PYR-1       ARSVDTVGVEIEQREVPVPAGHRVTVRIYR-----GGPPGSGVVLYCHSG
MSMEG_2568|M.smegmatis_MC2_155      AQTLDTFGVAIAGGRAALGR-RSVPVRIYR-----GGPSPAPVVVYCHSG
TH_2562|M.thermoresistible__bu      AAAVDTGGVHIDDREIHCGT-GPIEIRIYR-----GRRGVAPAVLYCHAG
MMAR_0404|M.marinum_M               ATETAAAGVAVADDVVTGEAGRPVPVRIYR-----AAPTPAPVVVYCHAG
MUL_1054|M.ulcerans_Agy99           ATETAAAGVAVADDVATGEAGRPVPVRIYR-----AAPTPAPVVVYCHAG
MAV_5118|M.avium_104                AAQTDTAGVRIVDDDANG-----VDVRIYR-----GGPEPAPAVIYCHAG
MAB_2814|M.abscessus_ATCC_1997      ARPPWIEVANIEDRTIPGPAG-EIPVRIYSP----AEGGVRPVFVLIHGG
MLBr_00314|M.leprae_Br4923          IDHAARVLLPVTNAARAEVNLSNTSAQLVRAAGVRPADGSGRIVLYLHGG
                                              :               ::               .:  *.*

Mb0223c|M.bovis_AF2122/97           GYVMGTAQQDDRLCLRFSSRLGITVASVDYRLAPENPYPAALGDCYSALT
Rv0217c|M.tuberculosis_H37Rv        GYVMGTAQQDDRLCLRFSSRLGITVASVDYRLAPENPYPAALGDCYSALT
Mflv_4102|M.gilvum_PYR-GCK          AFVLGNLDTDHRQCIEMARRGRCTVLSVDYRLAPEHPYPAAQDDVSAILD
Mvan_2244|M.vanbaalenii_PYR-1       AFVLGTLDTDHRQCIEMARRGRCTVLSVDYRLAPEHPYPAALDDAAAILD
MSMEG_2568|M.smegmatis_MC2_155      AFVLGNLDVDQRQCVELARRGQCTVVAMDYRLAPEHPYPAALDDAAMVLA
TH_2562|M.thermoresistible__bu      AFVLGNLDTDHRQCVELARRAECTVVSVDYRLAPEHPWPAAVDDATAVLS
MMAR_0404|M.marinum_M               GFALGNLDTDHRQCLELARRARCAVVSVDYRLAPEHPYPAALHDAIEVLT
MUL_1054|M.ulcerans_Agy99           GFALGNLDTDHRQCLERARRARCAVVSVDYRLAPEHPYPAALRDAIEVLT
MAV_5118|M.avium_104                GFALGNLDTDHRQCVELARRGRCTVVSVDYRLAPEHPYPAALQDAGTVLR
MAB_2814|M.abscessus_ATCC_1997      GWVIGDLDTHDAVARAAAVQADAVVVSVDYRLAPEHPYPAAVEDCWAALQ
MLBr_00314|M.leprae_Br4923          AFLGCGANSHRRLVETLSKLADSPILVVNYRLLPKHSIGMALDDCHDGYQ
                                    .:     : .       :      :  ::*** *::.   *  *      

Mb0223c|M.bovis_AF2122/97           WLASLP---AVDPARVAIGGASAGGGLAAALALLARDRGG-ITPAFQLLV
Rv0217c|M.tuberculosis_H37Rv        WLASLP---AVDPARVAIGGASAGGGLAAALALLARDRGG-ITPAFQLLV
Mflv_4102|M.gilvum_PYR-GCK          WAVRCSAELGIDATAVAVAGSSAGAALAAGLARRSAAGDG-PPVVFQMLH
Mvan_2244|M.vanbaalenii_PYR-1       WGVGNAAELGIDAAAVALAGSSAGASLVAGLAQRSAAGGA-PPVVFQLLH
MSMEG_2568|M.smegmatis_MC2_155      WVAAQAGELDVDPDRIAVAGSSAGGALAALLAQRSATGAA-PPIVFQLLH
TH_2562|M.thermoresistible__bu      WLAGNATALDVDPARLAVAGSSAGGALAAGLAQRSGRNGL-PQLVFQLLH
MMAR_0404|M.marinum_M               WVVGNATRLGFDARRLAVAGSSAGATLAAGLAHGAADGSL-PPVIFQLLH
MUL_1054|M.ulcerans_Agy99           WVVGNATRLGFDARRLAVAGSSAGATLAAGLAHGAADGSL-PPVIFQLLH
MAV_5118|M.avium_104                WVHAEAAALGVDPARLAVAGSSAGAALAACLAH--PDGSL-PAVVFQLLH
MAB_2814|M.abscessus_ATCC_1997      WVHEHAAEIGGDPGRLAVGGDSAGGNLSAVMAQLARDNGI-DLAFQVLWY
MLBr_00314|M.leprae_Br4923          WLRRLG----YDPEQIVLAGDSAGGYLALALAQRLQDVGEEPAALVAISP
                                    *          *.  :.:.* ***. *   :*               :  

Mb0223c|M.bovis_AF2122/97           YPMLDDRTSIAPANPHYR-LWNGRANRFGWRAYLG-DADARVA---VPGR
Rv0217c|M.tuberculosis_H37Rv        YPMLDDRPSIAPANPHYR-LWNGRANRFGWRAYLG-DADARVA---VPGR
Mflv_4102|M.gilvum_PYR-GCK          QPVLDDRPSPSKDEFTTTPGFDAEAVAWMWRHYGGDASLPDEA---VPAR
Mvan_2244|M.vanbaalenii_PYR-1       QPVLDDRPSPSKEEFTNTPGFDSQAVQWMWRHYGGGDPLPEDA---VPAR
MSMEG_2568|M.smegmatis_MC2_155      QPVLDDRPTRSKREFVDTPGFDGPATVAMWRHWLAGRAAPDGA---VPAR
TH_2562|M.thermoresistible__bu      QPALDDRVTPSKAEFCTTPGFDGPACDQMWRHYLAGAAPTAAA---APGR
MMAR_0404|M.marinum_M               QPVLDDRPTASRSEFRATPAFDGEAASLMWRHYLAGQTPSPES---VPGR
MUL_1054|M.ulcerans_Agy99           QPVLDDRPTASRSEFRATPAFDGEAASLMWRHYLAGQTPSPES---VPGR
MAV_5118|M.avium_104                QPVLDDRATGSKARFRTSPAFDGEAAELMWRYYLGPTVGSAAA---VPAR
MAB_2814|M.abscessus_ATCC_1997      PATTFDTTLPSMVENAEAPVLDFKTVGALSKWYLGDTNPATAGPTLVPAR
MLBr_00314|M.leprae_Br4923          LLQLAKKGKQAHPNAKTDAMFPPKAFDALGRLVASSAAKNKVDD--KPEE
                                         .    :  .          :     :   .            * .

Mb0223c|M.bovis_AF2122/97           RDD-----LGGLAPAWIGVGTHDLLHDEDLAYAERLTAAGVPCQVEVVEG
Rv0217c|M.tuberculosis_H37Rv        RDD-----LGGLAPAWIGVGTHDLLHDEDLAYAERLTAAGVPCQVEVVEG
Mflv_4102|M.gilvum_PYR-GCK          IEE-----MSSLPAALITCSELDPLRDEALDYALRLLWAGVAAELHVFSG
Mvan_2244|M.vanbaalenii_PYR-1       ADE-----LSELPATLITCSELDPLRDEAIDYALRLMWSGVNTELHVFSG
MSMEG_2568|M.smegmatis_MC2_155      ATE-----ISDMPAAFISCSELDPLRDEALDHARRLIDGGVSTELHVFAG
TH_2562|M.thermoresistible__bu      ADD-----LTGAPPAFISCSELDPLRDEALDYAARLLRCGVPTELHLFPG
MMAR_0404|M.marinum_M               RGQ-----LAGLPATLITCGEIDPFRDEVLDYAQRLLGAGVSTELHIFPR
MUL_1054|M.ulcerans_Agy99           RGQ-----LAGLPATLITCGEIDPFRDEVLDYAQRLLGAGVSTELHIFPR
MAV_5118|M.avium_104                RPE-----LAGLPPALITCAEIDPFRDEAIDYARRLLDAGVCTELHVFAR
MAB_2814|M.abscessus_ATCC_1997      AEN-----FEGLAPAFIGTAQFDPLRDDGAKYAELLRDAGVPVQLHNAPT
MLBr_00314|M.leprae_Br4923          LYEPLDHIAPGLPRTLIHVSGSEVLLHDAQLAATKLAAVGVPAEIRVWPG
                                      :         . : *  .  : : .:    *  *   **  ::.    

Mb0223c|M.bovis_AF2122/97           AFHGFDRVAPNVGVSQRFFTSQCNSLRAALALSNRT-----
Rv0217c|M.tuberculosis_H37Rv        AFHGFDRVAPNVGVSQRFFTSQCNSLRAALALSNRT-----
Mflv_4102|M.gilvum_PYR-GCK          TCHGFDSLVPEWEISRQLFDIQGTALRRAFLR---------
Mvan_2244|M.vanbaalenii_PYR-1       TCHGFDSLVPDWEVSSQLFDIQGAALRRAFLG---------
MSMEG_2568|M.smegmatis_MC2_155      TCHGFDSLLPEWEVSQELFTLQGAALRRALR----------
TH_2562|M.thermoresistible__bu      TCHGFDSLLPEWELSRQLFALQAAAVRRAFTTAEYPAGQVN
MMAR_0404|M.marinum_M               ACHGFDSLLPEWTTSQRLFAMQGHALADAFYPD--------
MUL_1054|M.ulcerans_Agy99           ACHGFDSLLPEWTTSQRLFAMQGHALADAFYPD--------
MAV_5118|M.avium_104                ACHGFDSLLPDWPGSQRLFALQGEVLSAALHRGSTH-----
MAB_2814|M.abscessus_ATCC_1997      LIHGYLGYADIVPSATEERDLSLAALKQALHG---------
MLBr_00314|M.leprae_Br4923          QVHVFQAAAPMVPEATLSLRQISQYIREATASKASRDRQSL
                                      * :         :          :  *