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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2802 | - | - | 100% (319) | esterase |
M. thermoresistible (build 8) | TH_2562 | - | 2e-37 | 42.44% (238) | PUTATIVE Alpha/beta hydrolase fold-3 domain protein |
M. thermoresistible (build 8) | TH_1220 | lipN | 8e-33 | 40.20% (199) | PROBABLE LIPASE/ESTERASE LIPN |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1435c | lipI | 5e-51 | 41.90% (284) | lipase LipH |
M. gilvum PYR-GCK | Mflv_4562 | - | 1e-130 | 72.38% (315) | alpha/beta hydrolase domain-containing protein |
M. tuberculosis H37Rv | Rv1400c | lipI | 5e-51 | 41.90% (284) | lipase LipH |
M. leprae Br4923 | MLBr_00314 | - | 1e-13 | 27.56% (254) | putative esterase |
M. abscessus ATCC 19977 | MAB_2814 | - | 4e-50 | 44.91% (265) | lipase LipH |
M. marinum M | MMAR_2209 | lipI | 6e-46 | 38.36% (292) | lipase LipI |
M. avium 104 | MAV_3032 | - | 1e-125 | 70.93% (313) | alpha/beta hydrolase domain-containing protein |
M. smegmatis MC2 155 | MSMEG_2875 | - | 1e-143 | 77.96% (313) | esterase |
M. ulcerans Agy99 | MUL_1795 | lipI | 5e-46 | 38.36% (292) | lipase LipI |
M. vanbaalenii PYR-1 | Mvan_2872 | - | 1e-138 | 75.24% (319) | alpha/beta hydrolase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb1435c|M.bovis_AF2122/97 MPSLDNTADEKPAIDPILLKVLDAVPFRLSIDD-GIEAVRQRLRDLP--R Rv1400c|M.tuberculosis_H37Rv MPSLDNTADEKPAIDPILLKVLDAVPFRLSIDD-GIEAVRQRLRDLP--R MMAR_2209|M.marinum_M MPSLDKTADEKPAIDPIMQKVLDAVPFRLSTED-GIDAVRQRLRDLP--R MUL_1795|M.ulcerans_Agy99 MPSLDKTADEKPAIDPIMQKVLDAVPFRLSTED-GIDAVRQRLRDLP--R MAB_2814|M.abscessus_ATCC_1997 ---MTATAG----IDPIIVKILEAVPIQLVSPD-GPQASRDAYRAIATAR TH_2802|M.thermoresistible__bu -----MNHP-VPPLDPDAAARIASLGPPAPMRRRGLQAVRDAIESAP-LP Mvan_2872|M.vanbaalenii_PYR-1 -----MNDPHRPALDPDAAARVAAFGPPVPIRDRGLQAVRDAIESAP-PP MSMEG_2875|M.smegmatis_MC2_155 MTTSPPSPPQGPPLDPDAAARIAGFGKPAPVRDRGLETVRAAIESAP-LP Mflv_4562|M.gilvum_PYR-GCK -------MP-GPTLDPDAAARVASFGPIPPMHERGLDAVRAGVENTP-VP MAV_3032|M.avium_104 --------MTSPPLDPDAAARIASFGETAPMRQRGLPAVRAGLESAP-RP MLBr_00314|M.leprae_Br4923 MAISAGAPVEIVESGPSIAARLASLTSRLTIRP--ILAVGSYVPQLPWPF .* : .. : . Mb1435c|M.bovis_AF2122/97 QPVHPELRVVDLAIDGPAGPIGTR-----IYWPPTCPDQAE-APVVLYFH Rv1400c|M.tuberculosis_H37Rv QPVHPELRVVDLAIDGPAGPIGTR-----IYWPPTCPDQAE-APVVLYFH MMAR_2209|M.marinum_M RPVHPELRVEDRAIDGPGGSIPIR-----IYWPPISPDATDPLPVVLFFH MUL_1795|M.ulcerans_Agy99 RPVHPELRVEDRAIDGPGGSIPIR-----IYWPPISPDATDPLPVVLFFH MAB_2814|M.abscessus_ATCC_1997 PPWIEVANIEDRTIPGPAGEIPVR-----IYSP----AEGGVRPVFVLIH TH_2802|M.thermoresistible__bu TDMPAMASIVDRAVPGPGGDIPVR-----IHRPERG--CGDPAPAVLYFH Mvan_2872|M.vanbaalenii_PYR-1 TDMPTMADIGDAEVAGPGGRVPVR-----IYRPAN---DGGPCPVIVHLH MSMEG_2875|M.smegmatis_MC2_155 SDMPPMAEIVDRTVPASDREIGVR-----VYRPEQV--GHDGAPVILHFH Mflv_4562|M.gilvum_PYR-GCK DDMPAMASIEERCAPGPDGPIPLR-----IYRPTD----ATDASVVVYFH MAV_3032|M.avium_104 ATMPEMASVTEALVPSAAGGIPVR-----IYRPTT----DSGVAVLVYLH MLBr_00314|M.leprae_Br4923 GLIDHAARVLLPVTNAARAEVNLSNTSAQLVRAAGVRPADGSGRIVLYLH : .. : : . .: :* Mb1435c|M.bovis_AF2122/97 GGGFVMGDLDTHDGTCRQHAVGADAIVVSVDYRLAPEHPYPAAIEDAWAA Rv1400c|M.tuberculosis_H37Rv GGGFVMGDLDTHDGTCRQHAVGADAIVVSVDYRLAPEHPYPAAIEDAWAA MMAR_2209|M.marinum_M GGGFVMGDLDTHDGTCRQHAVGADTLVVSVDYRLAPEHPYPAAIQDAWAA MUL_1795|M.ulcerans_Agy99 GGGFVMGDLDTHDGTCRQHAVGADTLVVSVDYRLAPEHPYPAAIQDAWAA MAB_2814|M.abscessus_ATCC_1997 GGGWVIGDLDTHDAVARAAAVQADAVVVSVDYRLAPEHPYPAAVEDCWAA TH_2802|M.thermoresistible__bu GGGLVMGSNHSFEPLARGLAAASGAVVVAVDYRLAPEHPPPAQFDDAWAT Mvan_2872|M.vanbaalenii_PYR-1 GGGLVMGSNRSFEPMARAMAAASGAAVVAVDYRLAPENPPPAQFEDAWTV MSMEG_2875|M.smegmatis_MC2_155 GGGLVMGSVHSFEPLARGLAAAAGAVVVAVDYRLAPEYPPPAQFDDAYAA Mflv_4562|M.gilvum_PYR-GCK GGGMVMGSNRSFEPLARALAAGSTATVVSVDYRLAPEHPAPAQFVDCSAV MAV_3032|M.avium_104 GGGLVMGSNRSFEPLARELASASAATVVAVDYRLAPESPPPAQFDDAYAA MLBr_00314|M.leprae_Br4923 GGAFLGCGANSHRRLVETLSKLADSPILVVNYRLLPKHSIGMALDDCHDG **. : . :. . : : : :: *:*** *: . . *. Mb1435c|M.bovis_AF2122/97 TRWVAEHGRQVGADLGRIAVAGDSAGGTIAAVIAQRARDMGG---PPIVF Rv1400c|M.tuberculosis_H37Rv TRWVAEHGRQVGADLGRIAVAGDSAGGTIAAVIAQRARDMGG---PPIVF MMAR_2209|M.marinum_M TRWVADHGSTIGADLNRVAVAGDSAGGTIAAVIAQQARDNADGPIPPIAF MUL_1795|M.ulcerans_Agy99 TRWVADHRSTIGADLNRVAVAGDSAGGTIAAVIAQQARDNADGPIPPIAF MAB_2814|M.abscessus_ATCC_1997 LQWVHEHAAEIGGDPGRLAVGGDSAGGNLSAVMAQLARDNGID----LAF TH_2802|M.thermoresistible__bu TRWVAAHADELGLDTSRLAVAGDSAGGALAAAVALAARDRGG---PELLA Mvan_2872|M.vanbaalenii_PYR-1 TKWVAADAERLRFDPGKIVVSGDSAGGGLAAAVTLAARDEGG---PRLFA MSMEG_2875|M.smegmatis_MC2_155 TEWVARHAEELGVDARRLVVAGDSAGGGLAAAVALAARDHGG---PAIFA Mflv_4562|M.gilvum_PYR-GCK TTWVAENATSLGVDPARLAVAGDSAGGSLAAAVTLAARDCGG---PVICA MAV_3032|M.avium_104 TEWVSRKAGELGVDADRLAVIGDSAGGSLAAAVALAARDRRG---PPICA MLBr_00314|M.leprae_Br4923 YQWLRR----LGYDPEQIVLAGDSAGGYLALALAQRLQDVGEEPAALVAI *: : * ::.: ****** :: .:: :* : Mb1435c|M.bovis_AF2122/97 QLLWYPSTLWDQSLPSLAENADAPILDVKAIAAFSRWYAGEIDLHNPPAP Rv1400c|M.tuberculosis_H37Rv QLLWYPSTLWDQSLPSLAENADAPILDVKAIAAFSRWYAGEIDLHNPPAP MMAR_2209|M.marinum_M QLLWYPSTMWDQTLPSFTENATGEVLDVKAIADFSRWYAGDTDLSNPPAG MUL_1795|M.ulcerans_Agy99 QLLWYPSTMWDQTLPSFTENATGEVLDVKAIADFSRWYAGDTDLSNPPAG MAB_2814|M.abscessus_ATCC_1997 QVLWYPATTFDTTLPSMVENAEAPVLDFKTVGALSKWYLGDTNPATAGPT TH_2802|M.thermoresistible__bu QLLMYPGLDRDLAAPSIVAMPEAPMLSRDDIVYLHELADLGAGTP-HDPY Mvan_2872|M.vanbaalenii_PYR-1 QVLMYPGLDRDMAAPSILANPHAPMLTHDDIVYLHELADIGAGTS-HDTR MSMEG_2875|M.smegmatis_MC2_155 QVLLYPGLDRDMGAQSIVEMPDAPMLSRDDILYMHDLADIGAGSP-HDPY Mflv_4562|M.gilvum_PYR-GCK QVLMYPGLDRDMAAPSMVAMPDAPLLSRADIDYMHELADDGVGAP-HDAY MAV_3032|M.avium_104 QVLLYPGLDRDMSVASIAAMPDAPLLIRDDIDYMHALVDGDAGPP-TDPY MLBr_00314|M.leprae_Br4923 SPLLQLAKKGKQAHPNAKTDAMFPPKAFDALGRLVASSAAKNKVDDKPEE . * . . . . : : Mb1435c|M.bovis_AF2122/97 MAPGRAENLADLPPAYIAVAGYDPLRDDGIRYGELLAAAGVPVEVHNAQT Rv1400c|M.tuberculosis_H37Rv MAPGRAENLADLPPAYIAVAGYDPLRDDGIRYGELLAAAGVPVEVHNAQT MMAR_2209|M.marinum_M MAPGRAENLANLPAAYIAVAGHDPLRDDGIRYGELLAAAGVSVEVHNAGS MUL_1795|M.ulcerans_Agy99 MAPGRAENLANLPAAYIAVAGHDPLRDDGIRYGELLAAAGVSVEVHNAGS MAB_2814|M.abscessus_ATCC_1997 LVPARAENFEGLAPAFIGTAQFDPLRDDGAKYAELLRDAGVPVQLHNAPT TH_2802|M.thermoresistible__bu RVPAYATDLGGLPQTIIVTGACDPIRDWGERYAGRLRDAGVQTTVTRYPG Mvan_2872|M.vanbaalenii_PYR-1 RVPAYATDLTGLPQAIMVTGELDPISDWGERYAARLRDAGVQTTVTRYPG MSMEG_2875|M.smegmatis_MC2_155 RVPAYADDLRGLPQAIVVTGECDPIRDWGERYADRLRAARVQTTLTRYPG Mflv_4562|M.gilvum_PYR-GCK RIPAYAEDLSGLPPAIVVTGECDPIRDWGERYAQRLRDARVQTTLTRYPG MAV_3032|M.avium_104 LVPAYAADLSGLPPAIVVTAGCDPIRDWGERYADRLRDAGVQTTVTRYPG MLBr_00314|M.leprae_Br4923 LYEPLDHIAPGLPRTLIHVSGSEVLLHDAQLAATKLAAVGVPAEIRVWPG .*. : : .. : : . . . * . * . : Mb1435c|M.bovis_AF2122/97 LVHGYVGYAGVVPAATEATNRGLVALRVVLHG----------------- Rv1400c|M.tuberculosis_H37Rv LVHGYVGYAGVVPAATEATNRGLVALRVVLHG----------------- MMAR_2209|M.marinum_M LVHGYIGYAGVVPAATTAMERGLAALRVALHG----------------- MUL_1795|M.ulcerans_Agy99 LVHGYIGYAGVVPAATTAMERGLAALRIALHG----------------- MAB_2814|M.abscessus_ATCC_1997 LIHGYLGYADIVPSATEERDLSLAALKQALHG----------------- TH_2802|M.thermoresistible__bu MYHGFLMRYESTARGRLALAEIGALLRAKFANPLPF------------- Mvan_2872|M.vanbaalenii_PYR-1 IYHGFLMRSEATARGRLAMAEIGALLRAKFANPLPFTTPLRCR------ MSMEG_2875|M.smegmatis_MC2_155 MYHGFLMRYEATARGRLALAETGALLRAKFADPLPFAG----------- Mflv_4562|M.gilvum_PYR-GCK MYHGFLMRPDGTARGRLAMAEIGALLRAKFAEPLPF------------- MAV_3032|M.avium_104 MYHGFLMRSDATARGRLAIAEIGGLLRAKFTHPLRFDVPITGRHSTPTR MLBr_00314|M.leprae_Br4923 QVHVFQAAAPMVPEATLSLRQISQYIREATASKASRDRQSL-------- * : .. . ::