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MAHRSGWTERLDPALREFAGARTDLSPETLAVVRASIDRRRRESAQTLDTFGVAIAGGRAALGRRSVPVR IYRGGPSPAPVVVYCHSGAFVLGNLDVDQRQCVELARRGQCTVVAMDYRLAPEHPYPAALDDAAMVLAWV AAQAGELDVDPDRIAVAGSSAGGALAALLAQRSATGAAPPIVFQLLHQPVLDDRPTRSKREFVDTPGFDG PATVAMWRHWLAGRAAPDGAVPARATEISDMPAAFISCSELDPLRDEALDHARRLIDGGVSTELHVFAGT CHGFDSLLPEWEVSQELFTLQGAALRRALR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2568 | - | - | 100% (310) | LipW protein |
| M. smegmatis MC2 155 | MSMEG_0280 | - | 1e-39 | 40.56% (249) | alpha/beta hydrolase fold |
| M. smegmatis MC2 155 | MSMEG_3059 | - | 4e-33 | 37.85% (251) | esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1435c | lipI | 3e-41 | 38.11% (286) | lipase LipH |
| M. gilvum PYR-GCK | Mflv_4102 | - | 1e-109 | 62.79% (301) | alpha/beta hydrolase domain-containing protein |
| M. tuberculosis H37Rv | Rv0217c | lipW | 2e-41 | 38.89% (306) | esterase LipW |
| M. leprae Br4923 | MLBr_00314 | - | 5e-13 | 27.52% (218) | putative esterase |
| M. abscessus ATCC 19977 | MAB_2814 | - | 3e-34 | 38.34% (253) | lipase LipH |
| M. marinum M | MMAR_0404 | lipW | 9e-99 | 58.69% (305) | esterase LipW |
| M. avium 104 | MAV_5118 | - | 1e-101 | 61.46% (301) | alpha/beta hydrolase domain-containing protein |
| M. thermoresistible (build 8) | TH_2562 | - | 1e-108 | 64.33% (300) | PUTATIVE Alpha/beta hydrolase fold-3 domain protein |
| M. ulcerans Agy99 | MUL_1054 | lipW | 6e-91 | 59.85% (274) | esterase LipW |
| M. vanbaalenii PYR-1 | Mvan_2244 | - | 1e-113 | 65.68% (303) | alpha/beta hydrolase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1435c|M.bovis_AF2122/97 MPSLDNTADEKPAIDPILLKVLDAVPFRLSIDDGIEAVRQRLRDLP----
MAB_2814|M.abscessus_ATCC_1997 ---MTATAG----IDPIIVKILEAVPIQLVSPDGPQASRDAYRAIAT---
Mflv_4102|M.gilvum_PYR-GCK ---MT--RDIAERLDPQLR--HLAAARTDLSPPVLGAVRDSLNQRRA-ET
Mvan_2244|M.vanbaalenii_PYR-1 ---MTD-RDITERLDPALR--HLAGARTDLSPPVLGAVRDSLNQRRA-ET
MSMEG_2568|M.smegmatis_MC2_155 ---MAHRSGWTERLDPALR--EFAGARTDLSPETLAVVRASIDRRRR-ES
TH_2562|M.thermoresistible__bu ----VNPPEAGQRLAPELR--HLWGTRTDLTADLLPTVRAVLDDRRR-AT
MMAR_0404|M.marinum_M ----MTQPEAVDRLDPLLR--AVATARIDFTAESILTIRESMNQRRREAA
MUL_1054|M.ulcerans_Agy99 -----------------------------------------MNQRRREAA
MAV_5118|M.avium_104 ----MTALDGAERLDPALR--AVATTRTDFSPAAIELTRAPFNERRR-LA
Rv0217c|M.tuberculosis_H37Rv --------MSGNEVHPDLRRIAVVTPRQLVGPRTLPVMRALIVVAGLRMS
MLBr_00314|M.leprae_Br4923 MAISAGAPVEIVESGPSIAARLASLTSRLTIRPILAVGSYVPQLPWPFGL
Mb1435c|M.bovis_AF2122/97 -RQPVHPELRVVDLAIDGPAG-PIGTRIYWPP-TCPDQAEAPVVLYFHGG
MAB_2814|M.abscessus_ATCC_1997 ARPPWIEVANIEDRTIPGPAG-EIPVRIYSP----AEGGVRPVFVLIHGG
Mflv_4102|M.gilvum_PYR-GCK ARTADLIGVEVEQREVPVPAGHTVTVRIYR-----GGPPQSPAVIYCHSG
Mvan_2244|M.vanbaalenii_PYR-1 ARSVDTVGVEIEQREVPVPAGHRVTVRIYR-----GGPPGSGVVLYCHSG
MSMEG_2568|M.smegmatis_MC2_155 AQTLDTFGVAIAGGRAALGR-RSVPVRIYR-----GGPSPAPVVVYCHSG
TH_2562|M.thermoresistible__bu AAAVDTGGVHIDDREIHCGT-GPIEIRIYR-----GRRGVAPAVLYCHAG
MMAR_0404|M.marinum_M ATETAAAGVAVADDVVTGEAGRPVPVRIYR-----AAPTPAPVVVYCHAG
MUL_1054|M.ulcerans_Agy99 ATETAAAGVAVADDVATGEAGRPVPVRIYR-----AAPTPAPVVVYCHAG
MAV_5118|M.avium_104 AAQTDTAGVRIVDDDANG-----VDVRIYR-----GGPEPAPAVIYCHAG
Rv0217c|M.tuberculosis_H37Rv RTPPDIEVLTLESG---------VGVRLYRPA---GSNEPAPALLWIHAG
MLBr_00314|M.leprae_Br4923 IDHAARVLLPVTNAARAEVNLSNTSAQLVRAAGVRPADGSGRIVLYLHGG
: :: .: *.*
Mb1435c|M.bovis_AF2122/97 GFVMGDLDTHDGTCRQHAVGADAIVVSVDYRLAPEHPYPAAIEDAWAATR
MAB_2814|M.abscessus_ATCC_1997 GWVIGDLDTHDAVARAAAVQADAVVVSVDYRLAPEHPYPAAVEDCWAALQ
Mflv_4102|M.gilvum_PYR-GCK AFVLGNLDTDHRQCIEMARRGRCTVLSVDYRLAPEHPYPAAQDDVSAILD
Mvan_2244|M.vanbaalenii_PYR-1 AFVLGTLDTDHRQCIEMARRGRCTVLSVDYRLAPEHPYPAALDDAAAILD
MSMEG_2568|M.smegmatis_MC2_155 AFVLGNLDVDQRQCVELARRGQCTVVAMDYRLAPEHPYPAALDDAAMVLA
TH_2562|M.thermoresistible__bu AFVLGNLDTDHRQCVELARRAECTVVSVDYRLAPEHPWPAAVDDATAVLS
MMAR_0404|M.marinum_M GFALGNLDTDHRQCLELARRARCAVVSVDYRLAPEHPYPAALHDAIEVLT
MUL_1054|M.ulcerans_Agy99 GFALGNLDTDHRQCLERARRARCAVVSVDYRLAPEHPYPAALRDAIEVLT
MAV_5118|M.avium_104 GFALGNLDTDHRQCVELARRGRCTVVSVDYRLAPEHPYPAALQDAGTVLR
Rv0217c|M.tuberculosis_H37Rv GYVMGTAQQDDRLCLRFSSRLGITVASVDYRLAPENPYPAALGDCYSALT
MLBr_00314|M.leprae_Br4923 AFLGCGANSHRRLVETLSKLADSPILVVNYRLLPKHSIGMALDDCHDGYQ
.: : . : : ::*** *::. * *
Mb1435c|M.bovis_AF2122/97 WVAEHGRQVGADLGRIAVAGDSAGGTIAAVIAQRARDMGGPPIVFQLLWY
MAB_2814|M.abscessus_ATCC_1997 WVHEHAAEIGGDPGRLAVGGDSAGGNLSAVMAQLARDNG-IDLAFQVLWY
Mflv_4102|M.gilvum_PYR-GCK WAVRCSAELGIDATAVAVAGSSAGAALAAGLARRSAAGDGPPVVFQMLHQ
Mvan_2244|M.vanbaalenii_PYR-1 WGVGNAAELGIDAAAVALAGSSAGASLVAGLAQRSAAGGAPPVVFQLLHQ
MSMEG_2568|M.smegmatis_MC2_155 WVAAQAGELDVDPDRIAVAGSSAGGALAALLAQRSATGAAPPIVFQLLHQ
TH_2562|M.thermoresistible__bu WLAGNATALDVDPARLAVAGSSAGGALAAGLAQRSGRNGLPQLVFQLLHQ
MMAR_0404|M.marinum_M WVVGNATRLGFDARRLAVAGSSAGATLAAGLAHGAADGSLPPVIFQLLHQ
MUL_1054|M.ulcerans_Agy99 WVVGNATRLGFDARRLAVAGSSAGATLAAGLAHGAADGSLPPVIFQLLHQ
MAV_5118|M.avium_104 WVHAEAAALGVDPARLAVAGSSAGAALAACLAH--PDGSLPAVVFQLLHQ
Rv0217c|M.tuberculosis_H37Rv WLASLP---AVDPARVAIGGASAGGGLAAALALLARDRGGITPAFQLLVY
MLBr_00314|M.leprae_Br4923 WLRRLG----YDPEQIVLAGDSAGGYLALALAQRLQDVGEEPAALVAISP
* * :.:.* ***. : :* : :
Mb1435c|M.bovis_AF2122/97 PSTLWDQSLPSLAENADAPILDVKAIAAFSRWYAGEIDLHNPP---APMA
MAB_2814|M.abscessus_ATCC_1997 PATTFDTTLPSMVENAEAPVLDFKTVGALSKWYLGDTNPATAG---PTLV
Mflv_4102|M.gilvum_PYR-GCK P-VLDDRPSPSKDEFTTTPGFDAEAVAWMWRHYGGDASLPDE------AV
Mvan_2244|M.vanbaalenii_PYR-1 P-VLDDRPSPSKEEFTNTPGFDSQAVQWMWRHYGGGDPLPED------AV
MSMEG_2568|M.smegmatis_MC2_155 P-VLDDRPTRSKREFVDTPGFDGPATVAMWRHWLAGRAAPDG------AV
TH_2562|M.thermoresistible__bu P-ALDDRVTPSKAEFCTTPGFDGPACDQMWRHYLAGAAPTAA------AA
MMAR_0404|M.marinum_M P-VLDDRPTASRSEFRATPAFDGEAASLMWRHYLAGQTPSPE------SV
MUL_1054|M.ulcerans_Agy99 P-VLDDRPTASRSEFRATPAFDGEAASLMWRHYLAGQTPSPE------SV
MAV_5118|M.avium_104 P-VLDDRATGSKARFRTSPAFDGEAAELMWRYYLGPTVGSAA------AV
Rv0217c|M.tuberculosis_H37Rv P-MLDDRPSIAPANPHYR-LWNGRANRFGWRAYLG-DADARV------AV
MLBr_00314|M.leprae_Br4923 LLQLAKKGKQAHPNAKTDAMFPPKAFDALGRLVASSAAKNKVDDKPEELY
. : . : : .
Mb1435c|M.bovis_AF2122/97 PGRAENLADLPPAYIAVAGYDPLRDDGIRYGELLAAAGVPVEVHNAQTLV
MAB_2814|M.abscessus_ATCC_1997 PARAENFEGLAPAFIGTAQFDPLRDDGAKYAELLRDAGVPVQLHNAPTLI
Mflv_4102|M.gilvum_PYR-GCK PARIEEMSSLPAALITCSELDPLRDEALDYALRLLWAGVAAELHVFSGTC
Mvan_2244|M.vanbaalenii_PYR-1 PARADELSELPATLITCSELDPLRDEAIDYALRLMWSGVNTELHVFSGTC
MSMEG_2568|M.smegmatis_MC2_155 PARATEISDMPAAFISCSELDPLRDEALDHARRLIDGGVSTELHVFAGTC
TH_2562|M.thermoresistible__bu PGRADDLTGAPPAFISCSELDPLRDEALDYAARLLRCGVPTELHLFPGTC
MMAR_0404|M.marinum_M PGRRGQLAGLPATLITCGEIDPFRDEVLDYAQRLLGAGVSTELHIFPRAC
MUL_1054|M.ulcerans_Agy99 PGRRGQLAGLPATLITCGEIDPFRDEVLDYAQRLLGAGVSTELHIFPRAC
MAV_5118|M.avium_104 PARRPELAGLPPALITCAEIDPFRDEAIDYARRLLDAGVCTELHVFARAC
Rv0217c|M.tuberculosis_H37Rv PGRRDDLGGLAPAWIGVGTHDLLHDEDLAYAERLTAAGVPCQVEVVEGAF
MLBr_00314|M.leprae_Br4923 EPLDHIAPGLPRTLIHVSGSEVLLHDAQLAATKLAAVGVPAEIRVWPGQV
. : * . : : .: . * ** ::.
Mb1435c|M.bovis_AF2122/97 HGYVGYAGVVPAATEATNRGLVALRVVLHG---------
MAB_2814|M.abscessus_ATCC_1997 HGYLGYADIVPSATEERDLSLAALKQALHG---------
Mflv_4102|M.gilvum_PYR-GCK HGFDSLVPEWEISRQLFDIQGTALRRAFLR---------
Mvan_2244|M.vanbaalenii_PYR-1 HGFDSLVPDWEVSSQLFDIQGAALRRAFLG---------
MSMEG_2568|M.smegmatis_MC2_155 HGFDSLLPEWEVSQELFTLQGAALRRALR----------
TH_2562|M.thermoresistible__bu HGFDSLLPEWELSRQLFALQAAAVRRAFTTAEYPAGQVN
MMAR_0404|M.marinum_M HGFDSLLPEWTTSQRLFAMQGHALADAFYPD--------
MUL_1054|M.ulcerans_Agy99 HGFDSLLPEWTTSQRLFAMQGHALADAFYPD--------
MAV_5118|M.avium_104 HGFDSLLPDWPGSQRLFALQGEVLSAALHRGSTH-----
Rv0217c|M.tuberculosis_H37Rv HGFDRVAPNVGVSQRFFTSQCNSLRAALALSNRT-----
MLBr_00314|M.leprae_Br4923 HVFQAAAPMVPEATLSLRQISQYIREATASKASRDRQSL
* : : : .