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M. thermoresistible (build 8) TH_2573 (-)

annotation: Alpha/beta hydrolase fold-3 domain protein
coordinates: 3710272 - 3711186
length: 305

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2573--100% (305)Alpha/beta hydrolase fold-3 domain protein
M. thermoresistible (build 8)TH_2562-2e-3940.94% (254) PUTATIVE Alpha/beta hydrolase fold-3 domain protein
M. thermoresistible (build 8)TH_2802-1e-3137.31% (268) PUTATIVE esterase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0223clipW1e-10765.65% (294) esterase LipW
M. gilvum PYR-GCKMflv_0442-1e-12873.83% (298) alpha/beta hydrolase domain-containing protein
M. tuberculosis H37RvRv0217clipW1e-10665.31% (294) esterase LipW
M. leprae Br4923MLBr_00314-6e-2433.60% (250) putative esterase
M. abscessus ATCC 19977MAB_0826c-1e-10161.64% (292) esterase LipW
M. marinum MMMAR_2621-1e-7652.26% (287) esterase/lipase
M. avium 104MAV_4954-1e-11567.80% (295) alpha/beta hydrolase fold
M. smegmatis MC2 155MSMEG_0280-1e-11769.05% (294) alpha/beta hydrolase fold
M. ulcerans Agy99MUL_3141-8e-4948.13% (214) esterase/lipase
M. vanbaalenii PYR-1Mvan_0225-1e-12773.97% (292) alpha/beta hydrolase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb0223c|M.bovis_AF2122/97           ----------------------MSGNEVHPDLRRIAVVTPRQLVGPRTLP
Rv0217c|M.tuberculosis_H37Rv        ----------------------MSGNEVHPDLRRIAVVTPRQLVGPRTLP
MAV_4954|M.avium_104                --------------MAVGDTDPVPNNDVHPDLQRFARFAPRRLVGPRTLP
Mflv_0442|M.gilvum_PYR-GCK          ----------------------MHGVDFHPELRRAARMLPRQVVTPVTLP
Mvan_0225|M.vanbaalenii_PYR-1       ------------MPLPHTHTERVPDIEFHPELRRSARLLPKQVITPLTLP
TH_2573|M.thermoresistible__bu      ----------------VARSSKLP-LDFHPDLRRLARFIPRQAVSPVTLP
MSMEG_0280|M.smegmatis_MC2_155      -------------------MTATTPTRFHPDLERVARYIPRHMVNRATLP
MAB_0826c|M.abscessus_ATCC_199      ----------------------MSSPDIHPDLRLAARAFPRQVGLPRTLS
MMAR_2621|M.marinum_M               -----------MQARSDGPPAFTKPDAIDPALRAISRILPRGYGLHRGLK
MUL_3141|M.ulcerans_Agy99           MRTPRCAIVWCMQARPDGPPAFTKPDAIDPALRAISRILPRGYGLHRGLK
MLBr_00314|M.leprae_Br4923          --------------MAISAGAPVEIVESGPSIAARLASLTSRLTIRPILA
                                                                 * :       .        * 

Mb0223c|M.bovis_AF2122/97           VMRALIVVAGLRMSRTPPDIEVLTLE---------SGVGVRLYRPAGSNE
Rv0217c|M.tuberculosis_H37Rv        VMRALIVVAGLRMSRTPPDIEVLTLE---------SGVGVRLYRPAGSNE
MAV_4954|M.avium_104                LMRVALAWRG-RLGKPVRDVEVITLG---------SGVGVRLFRPAGAAE
Mflv_0442|M.gilvum_PYR-GCK          LLRRASRLMWRRAPAP--DVEVLTLE---------SGVGVRLFRPAGATR
Mvan_0225|M.vanbaalenii_PYR-1       FIRAASRLMWRRNDSPA-DVEVLTLS---------SGVGVRLFRPSGVAP
TH_2573|M.thermoresistible__bu      LMRLATRPMTRR--APR-DIEVLTLS---------SGIGIRLFRPPGGGT
MSMEG_0280|M.smegmatis_MC2_155      VFQRLTRLMGRR--VPP-GCEVLTLP---------SGVGIRLFRPPASTT
MAB_0826c|M.abscessus_ATCC_199      ILRASIYLTDLL---PRHGVRRIAVN---------DNVTVRAHVPKNLEE
MMAR_2621|M.marinum_M               LPRALMKLAGITG--RLRDVPVVAVN---------DAVSVRLHRPTGLPD
MUL_3141|M.ulcerans_Agy99           LPRALMKLAGITG--RLRDVPVVAVN---------DAVSVRSHRPAGLPD
MLBr_00314|M.leprae_Br4923          VGSYVPQLPWPFGLIDHAARVLLPVTNAARAEVNLSNTSAQLVRAAGVRP
                                    .                     :.:          .    :   .     

Mb0223c|M.bovis_AF2122/97           ---PAPALLWIHAGGYVMGTAQQDDRLCLRFSSRLGITVASVDYRLAPEN
Rv0217c|M.tuberculosis_H37Rv        ---PAPALLWIHAGGYVMGTAQQDDRLCLRFSSRLGITVASVDYRLAPEN
MAV_4954|M.avium_104                ---TTPALLWIHGGGYVLGTAQQDDQLCSRFSRRLGITVASVDYRLAPEH
Mflv_0442|M.gilvum_PYR-GCK          ---PGPALLWIHGGGYILGDAAQDDVLCRRFAHELGATVASVDYRLAPEF
Mvan_0225|M.vanbaalenii_PYR-1       G--RGPALLWIHGGGYVIGDAAQDDVLCRRFARELGATVASVNYRLAPEY
TH_2573|M.thermoresistible__bu      ----GAAMLWIHGGGYVIGCAAQDDALCRRYARELDVTVAAVDYRLAPEN
MSMEG_0280|M.smegmatis_MC2_155      L--PGPALVWIHGGGYVLGSAAQDDAQCLQFARQAGVTVASVEYRLAPQN
MAB_0826c|M.abscessus_ATCC_199      ---PSAALLWIHGGGYVMGTARQDDFFCRKVMHETGIPVVSVDYRLAPEH
MMAR_2621|M.marinum_M               ---PGPALLWIHGGGTVMGSAAQEDQYCRKLSHLAGVAVAAVDYRLAPEH
MUL_3141|M.ulcerans_Agy99           ---PGPALLWIHGGGTVMGSAAQEDQYCRKLSHLAGVAVAAVDYRLAPEH
MLBr_00314|M.leprae_Br4923          ADGSGRIVLYLHGGAFLGCGANSHRRLVETLSKLADSPILVVNYRLLPKH
                                           ::::*.*. :   * ..           . .:  *:*** *: 

Mb0223c|M.bovis_AF2122/97           PYPAALGDCYSALTWLASLPAVDPARVAIGGASAGGGLAAALALLARDRG
Rv0217c|M.tuberculosis_H37Rv        PYPAALGDCYSALTWLASLPAVDPARVAIGGASAGGGLAAALALLARDRG
MAV_4954|M.avium_104                RYPVPLEDCYTALTWLAGLPSVDRYRIAIGGASAGGGLAAALALLARDRA
Mflv_0442|M.gilvum_PYR-GCK          PYPAPVEDCYSALKWLSALPAVDPSRVAIGGASAGGGIAAALAFLARDRG
Mvan_0225|M.vanbaalenii_PYR-1       PYPVPVEDCYSALHWLTQLPSVDPARVAIGGASAGGGLAAALALLTRDRG
TH_2573|M.thermoresistible__bu      PYPIPLEDCYAALLWLTRLPTVDPQRVVIAGGSAGGGLAAALALLARDRG
MSMEG_0280|M.smegmatis_MC2_155      PYPAGLEDCFAALRWLTALPSVDPARVAIGGASAGGGLAASLALLARDRG
MAB_0826c|M.abscessus_ATCC_199      PYPIPLEDCYAALRWLSVQGWIDPTRIAVGGASAGGGLAAALALLARDRG
MMAR_2621|M.marinum_M               PYPTPVEDCYAALLWLRQQQWVDPSRIAVAGASAGGLFAATLVQLACDRG
MUL_3141|M.ulcerans_Agy99           PYPTPVEDCYAALLWLRQQQWVDPSRIAVAGASAGDLFAATLVQLACDRG
MLBr_00314|M.leprae_Br4923          SIGMALDDCHDGYQWLRRLG-YDPEQIVLAGDSAGGYLALALAQRLQDVG
                                         : **. .  **      *  ::.:.* ***. :* :*.    * .

Mb0223c|M.bovis_AF2122/97           GITPAFQLLVYPMLDDRTSIAP--ANPHYRLWNGRANRFGWRAYLG----
Rv0217c|M.tuberculosis_H37Rv        GITPAFQLLVYPMLDDRPSIAP--ANPHYRLWNGRANRFGWRAYLG----
MAV_4954|M.avium_104                EVSPAFQLLTYPMLDDRSSDTA--PSPNYRLWDNRSNRFGWAAYLG----
Mflv_0442|M.gilvum_PYR-GCK          EIPLAAQLLVYPMIDDRTVLRTGLDNPGHRLWNQAANRFGWQAYLG----
Mvan_0225|M.vanbaalenii_PYR-1       EIELAAQLLVYPMIDDRTVHRKGLDHPGHRLWNQSSNRFGWRAYLG----
TH_2573|M.thermoresistible__bu      EVAPVAQLLVYPMLDDRTLHRTDLDHPGLRLWNQSSNRFGWSAYLG----
MSMEG_0280|M.smegmatis_MC2_155      -IDVAAQLLVYPMLDDRSSFVPSLDHPGQRLWNQGSNRFGWKAYLG----
MAB_0826c|M.abscessus_ATCC_199      EVAPAAQLLIYPMLDDRSSERTDIDGTNLRLWSGDSNRFGWDSYLG----
MMAR_2621|M.marinum_M               DVEPVLQMLVYPMLDDRTGSGP--NGHKRIMWSERDNQQAWQLYLA----
MUL_3141|M.ulcerans_Agy99           DVEPVLQMLVYPMLDDRTGSGP--NGHKRIMWSERDNQQAWQLYLA----
MLBr_00314|M.leprae_Br4923          EEPAALVAISPLLQLAKKGKQAHPNAKTDAMFPPKAFDALGRLVASSAAK
                                        .   :   :   :             ::             .    

Mb0223c|M.bovis_AF2122/97           ---DADARVAVPGRRDDLGGLAPAWIGVGTHDLLHDEDLAYAERLTAAGV
Rv0217c|M.tuberculosis_H37Rv        ---DADARVAVPGRRDDLGGLAPAWIGVGTHDLLHDEDLAYAERLTAAGV
MAV_4954|M.avium_104                ---DADPHVAVPARRDDLSGLPPAWIGVGTHDLFHDEDLAYAERLRAAGV
Mflv_0442|M.gilvum_PYR-GCK          ---DADRDVAVPARRDDLAGLPPAWIGVGTLDLFHDEDLAYAERLRAAGV
Mvan_0225|M.vanbaalenii_PYR-1       ---DADPNEAVPARRDDLAGLPPAWIGVGTLDLFHDEDLAYAERLRVAGV
TH_2573|M.thermoresistible__bu      ---DADPEVAVPARQTDLAGLPPAWIGVGTYDLFHDEDLAYAERLRAAGV
MSMEG_0280|M.smegmatis_MC2_155      ---DADPDVAVPARREDLSGLPPAWVGVGTLDLFHDEDLAYAGRLHAAGV
MAB_0826c|M.abscessus_ATCC_199      ---DADRDIAVPGRRTDVAGLAPAWIGIGTADLFHDEDLAYAERLRTAGV
MMAR_2621|M.marinum_M               ---GADPSTAAPARRADLSNLPPAWIGVGTLDLFHQECLDYAARLRDAGV
MUL_3141|M.ulcerans_Agy99           ---GADPSTAAPA-------------------------------------
MLBr_00314|M.leprae_Br4923          NKVDDKPEELYEPLDHIAPGLPRTLIHVSGSEVLLHDAQLAATKLAAVGV
                                       . .                                            

Mb0223c|M.bovis_AF2122/97           PCQVEVVEGAFHGFDRVAPNVGVSQRFFTSQCNSLRAALALSNRT-----
Rv0217c|M.tuberculosis_H37Rv        PCQVEVVEGAFHGFDRVAPNVGVSQRFFTSQCNSLRAALALSNRT-----
MAV_4954|M.avium_104                PCQVETIPGAFHGFDLILPKVQVSQRFFDSQCNSLRAALTPAG-------
Mflv_0442|M.gilvum_PYR-GCK          PCEVEVVKGAFHGFDGIAPKAEVSQSFFRSQCALLRGAFEPAAA------
Mvan_0225|M.vanbaalenii_PYR-1       QCEVMVVDGAFHGFDGIAPKADVSQSFFNSQCALLRTVFASAAP------
TH_2573|M.thermoresistible__bu      PCEVEVVPGAFHGFDAIAPRAGVSRQFFDSQCAMLRGLLRPEAA------
MSMEG_0280|M.smegmatis_MC2_155      PCEIDVVHGAFHGFDGVAPKAAVSRAFRNAQCAFLKRALT----------
MAB_0826c|M.abscessus_ATCC_199      PCELEVVPGAFHGFDKLVPWAGVSRDFVAKACRSLLGALS----------
MMAR_2621|M.marinum_M               EVHEQIADGAFHAFDLLAPNAQVSLGFFASQCQFLRTHLHATVSDQPQAP
MUL_3141|M.ulcerans_Agy99           --------------------------------------------------
MLBr_00314|M.leprae_Br4923          PAEIRVWPGQVHVFQAAAPMVPEATLSLRQISQYIREATASKASRDRQSL