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M. thermoresistible (build 8) TH_1254 (-)

annotation: alcohol dehydrogenase B
coordinates: 2399891 - 2401018
length: 376

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1254--100% (376)alcohol dehydrogenase B
M. thermoresistible (build 8)TH_0605-e-13358.82% (374) alcohol dehydrogenase B
M. thermoresistible (build 8)TH_2786-e-10852.16% (370) PUTATIVE Alcohol dehydrogenase GroES domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0784cadhB0.084.00% (375) zinc-containing alcohol dehydrogenase NAD dependant ADHB
M. gilvum PYR-GCKMflv_1593-0.084.04% (376) alcohol dehydrogenase
M. tuberculosis H37RvRv0761cadhB0.084.00% (375) zinc-containing alcohol dehydrogenase NAD dependent ADHB
M. leprae Br4923MLBr_01784adhE23e-4532.61% (368) putative alcohol dehydrogenase (Zn dependent)
M. abscessus ATCC 19977MAB_4560-1e-13359.36% (374) alcohol dehydrogenase B
M. marinum MMMAR_4935adhB0.085.33% (375) zinc-containing alcohol dehydrogenase NAD- dependent AdhB
M. avium 104MAV_0705-0.085.87% (375) alcohol dehydrogenase B
M. smegmatis MC2 155MSMEG_5866-0.089.33% (375) alcohol dehydrogenase B
M. ulcerans Agy99MUL_0470adhB0.084.80% (375) zinc-containing alcohol dehydrogenase NAD- dependent AdhB
M. vanbaalenii PYR-1Mvan_5164-0.084.04% (376) alcohol dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1593|M.gilvum_PYR-GCK          ---------MKTKGALIWEFNQPWSIEEIEIGDPVKDEVKIQMEASGMCH
Mvan_5164|M.vanbaalenii_PYR-1       ---------MKTKGALIWEFNQPWTIEEIEIGDPVKDEVKIQMEASGMCH
MSMEG_5866|M.smegmatis_MC2_155      ---------MKTKGALIWEFNQPWSIEEIEIGDPVKDEVKIQMEASGMCH
TH_1254|M.thermoresistible__bu      ---------MKTKGALIWEFNQPWSVEEIEIGDPVKDEVKIRMEASGMCH
MMAR_4935|M.marinum_M               ---------MKTKGALIWEFNQPWSVEDIEIGDPVKDEVKIQMEAAGMCR
MUL_0470|M.ulcerans_Agy99           ---------MKTKGALIWEFNQPWSVEDIEIGDPVKDEVKIQMEAAGMCR
MAV_0705|M.avium_104                ---------MKTKGALIWEFNQPWSIEEIEIGDPQAHEVKIQMEAAGMCH
Mb0784c|M.bovis_AF2122/97           ---------MKTKGALIWEFNQPWSVEEIEIGDPRKDEVKIQMEAAGMCR
Rv0761c|M.tuberculosis_H37Rv        ---------MKTKGALIWEFNQPWSVEEIEIGDPRKDEVKIQMEAAGMCR
MAB_4560|M.abscessus_ATCC_1997      MYLEGLAESMKTKGALIRELNKPIVVEEITFGDPAEGEVQVQLHAAGMCH
MLBr_01784|M.leprae_Br4923          -------MSQTVRGVISRKKDEPVELVDIVIPDPGPGEAVVDVTACGVCH
                                              ..:*.:  : ::*  : :* : **   *. : : *.*:*:

Mflv_1593|M.gilvum_PYR-GCK          SDHHLVTGDIPMAGFPVLGGHEGAGIVTEVGPGVEGLEPGDHVVLSFIPS
Mvan_5164|M.vanbaalenii_PYR-1       SDHHLVTGDIPMAGFPVLGGHEGAGVVTEVGPGVEGLEPGDHVVLSFIPS
MSMEG_5866|M.smegmatis_MC2_155      SDHHLVTGGIPMGGFPVLGGHEGAGIVTEVGPGVEGIEPGDHVVLSFIPS
TH_1254|M.thermoresistible__bu      SDHHLVTGGIPMGGFPVLGGHEGAGVVEEVGPGVEEVQPGDHVVLSFIPS
MMAR_4935|M.marinum_M               SDNHLVTGGIPMAGFPVLGGHEGAGVVTEVGPGVDDIAPGDHVVLSFIPS
MUL_0470|M.ulcerans_Agy99           SDNHLVTGGIPMAGFPVLGGHEGAGVVTEVGPGVDDIAPGDHVVLSFIPS
MAV_0705|M.avium_104                SDHHLVTGGIPMAGFPVLGGHEGAGIVTEVGPGVEDIAPGDHVVLSFIPS
Mb0784c|M.bovis_AF2122/97           SDHHLVTGDIPMAGFPVLGGHEGAGIVTEVGPGVDDFAPGDHVVLAFIPS
Rv0761c|M.tuberculosis_H37Rv        SDHHLVTGDIPMAGFPVLGGHEGAGIVTEVGPGVDDFAPGDHVVLAFIPS
MAB_4560|M.abscessus_ATCC_1997      SDYHVLTGATPME-LPVLPGHEGAGVVTKVGKGVTSVQEGDHVIFAFIPA
MLBr_01784|M.leprae_Br4923          TDLTYREGGINDR-YPFLLGHEAAGTVEVVGPGVTAVEPGDFVILNWRAV
                                    :*     *       *.* ***.** *  ** **  .  **.*:: : . 

Mflv_1593|M.gilvum_PYR-GCK          CGACPSCQAGLRNLCDLGAMLLQGTAVSDNTHRIHAADGTPVIPMTLLGT
Mvan_5164|M.vanbaalenii_PYR-1       CGSCPSCQAGMRNLCDLGAMLLQGTAVSDNTHRIHAKDGTPVIPMTLLGT
MSMEG_5866|M.smegmatis_MC2_155      CGSCPSCQAGLRNLCDLGAGLLGGVAVADGTHRIHAN-GKPVFPMTLLGT
TH_1254|M.thermoresistible__bu      CGQCPSCQAGLRNLCDLGAGLLNGAAVSDGTFRITAR-GQNVYPMTLLGT
MMAR_4935|M.marinum_M               CGRCPTCQAGLRNLCDLGAGLLAGAAVSDGTFRIQAR-GQNVYPMTLLGT
MUL_0470|M.ulcerans_Agy99           CGRCPTCQAGLRNLCDLGAGLLAGAAVSDGTFRIQAR-GQNVYPMTLLGT
MAV_0705|M.avium_104                CGSCPTCQAGMRNLCDLGAGLLGGEAVSDGTFRIQAR-GQNVYPMTLLGT
Mb0784c|M.bovis_AF2122/97           CGKCPSCQAGMRNLCDLGAGLLAGESVTDGSFRIQAR-GQNVYPMTLLGT
Rv0761c|M.tuberculosis_H37Rv        CGKCPSCQAGMRNLCDLGAGLLAGESVTDGSFRIQAR-GQNVYPMTLLGT
MAB_4560|M.abscessus_ATCC_1997      CGKCPPCMRGYRSLCDRGAILLGGKAIADGTNRIHAG-NTPVSAMNLLGT
MLBr_01784|M.leprae_Br4923          CGQCRACKRGRPSYCFDTFNAQQKMTLIDG---------TELTPALGIGA
                                    ** * .*  *  . *          :: *.           : .   :*:

Mflv_1593|M.gilvum_PYR-GCK          FSPYMVVHKSSVVKIDPSIPFEVACLVGCGVTTGYGSAVRSADVRPGDDV
Mvan_5164|M.vanbaalenii_PYR-1       FSPYMVVHKSSVVKIDPSIPFEVACLVGCGVTTGYGSAVRSANVRPGDDV
MSMEG_5866|M.smegmatis_MC2_155      FSPYMVVHKSSVVKIDKSIPFEVACLVGCGVTTGYGSAVRSGDIRPGDDV
TH_1254|M.thermoresistible__bu      FSPYMVVHKSSVVKIDKDIPFEVACLVGCGVTTGYGSAVRSGDVRPGDDV
MMAR_4935|M.marinum_M               FSPYMVVHRSSVVKIDPAIPFEVAALVGCGVTTGYGSAVRTADVRPGDDV
MUL_0470|M.ulcerans_Agy99           FSPYMVVHRSSVVKIDPAIPFEVAALVGCGVTTGYGSAVRTADVRPGDDV
MAV_0705|M.avium_104                FSPYMVVHRSSVVKIDPSIPFEVAALVGCGVTTGYGSAVRTADIRPGQDV
Mb0784c|M.bovis_AF2122/97           FSPYMVVHRSSVVKIDPSVPFEVACLVGCGVTTGYGSAVRTADVRPGDDV
Rv0761c|M.tuberculosis_H37Rv        FSPYMVVHRSSVVKIDPSVPFEVACLVGCGVTTGYGSAVRTADVRPGDDV
MAB_4560|M.abscessus_ATCC_1997      FSPYAVVHEDSVVKIDDDVPFESAALLGCAVPTGFGSSTNIAEVKPGEDV
MLBr_01784|M.leprae_Br4923          FADKTLVHSGQCTKVDPAADPAVAGLLGCGVMAGLGAAINTAAVSRDDTV
                                    *:   :** .. .*:*       * *:**.* :* *:: . . :  .: *

Mflv_1593|M.gilvum_PYR-GCK          VIAGIGGVGMGALQGALNAGARNIFAIDPVEWKRDQALKFGATHAYPDIF
Mvan_5164|M.vanbaalenii_PYR-1       VIAGIGGVGMGALQGALNAGARTIFAIDPVEWKRDQALKFGATHAYPDIF
MSMEG_5866|M.smegmatis_MC2_155      AIFGIGGVGMGALQGAVNAGARYIFAIDPVEWKRDQALKFGATHVYPDVF
TH_1254|M.thermoresistible__bu      AIVGVGGVGMGALQGAVNAGARYIFAIDPVEWKRDQALKFGATHVYPDIE
MMAR_4935|M.marinum_M               AIVGLGGVGMAALQGAVTAGARYIFAVEPVEWKRDQALKFGATHVYPDME
MUL_0470|M.ulcerans_Agy99           AIVGLGGVGMAALQGAVTAGARYIFAVEPVEWKRDQALKFGATHVYPDME
MAV_0705|M.avium_104                AIVGVGGVGMAALQGAVNAGARYIFAIDPVEWKRDQALKFGATHVYPDIM
Mb0784c|M.bovis_AF2122/97           AIVGLGGVGMAALQGAVSAGARYVFAVEPVEWKRDQALKFGATHVYPDIN
Rv0761c|M.tuberculosis_H37Rv        AIVGLGGVGMAALQGAVSAGARYVFAVEPVEWKRDQALKFGATHVYPDIN
MAB_4560|M.abscessus_ATCC_1997      IIVGIGGIGMSALQGAVVSGARRVIAIDPVPWKREQALKFGATHAFPTMA
MLBr_01784|M.leprae_Br4923          AVIGCGGVGDAAISGAALVGANRIIAVDIDDTKLEWARTFGATHTVNALE
                                     : * **:* .*:.**   **. ::*::    * : * .*****.   : 

Mflv_1593|M.gilvum_PYR-GCK          SAMAG-VAELTQGRMAAKTIITTGELHGEEIDNYLNITSKGGTCVVTAVA
Mvan_5164|M.vanbaalenii_PYR-1       SAMAG-VAEVTQGRMASKTIITTGELHGEEIDNYLNITAKGGTCVVTAVA
MSMEG_5866|M.smegmatis_MC2_155      SAMAG-IAEVTAGGMAKKVIVTVGELHGEDIDNYLNVTSKGGTCVVTAVG
TH_1254|M.thermoresistible__bu      SAMAG-IAEVTWGLMAKKVIVTVGELKGEDIDAYVNLTAKGGTCVLTAIG
MMAR_4935|M.marinum_M               AALMG-IAEVTYGLMAKKVVITVGELQGSDIDTYLAITSKGGTCVVTAIG
MUL_0470|M.ulcerans_Agy99           AALMG-IAEVTYGLMAKKVMITVGELQGSDIDTYLAITSKGGTCVVTAIG
MAV_0705|M.avium_104                AAMAG-MAEVTYGLMAHKVVVTVGELQGADVDNYLNITQKGGTCVLTAIG
Mb0784c|M.bovis_AF2122/97           AALMG-IAEVTYGLMAQKVIITVGKLDGADVDSYLTITAKGGTCVLTAIG
Rv0761c|M.tuberculosis_H37Rv        AALMG-IAEVTYGLMAQKVIITVGKLDGADVDSYLTITAKGGTCVLTAIG
MAB_4560|M.abscessus_ATCC_1997      EALLP-VMDLTWGIMAQKTIITVGEMRGEMIEEAMLLTAKTGTCVVTGMG
MLBr_01784|M.leprae_Br4923          LEVVKTIQDLTSGFGVDVVIDTVGRP--ETWKQAFYARDLAGTVVLVGVP
                                      :   : ::* *  .  .: *.*.      .  .      ** *:..: 

Mflv_1593|M.gilvum_PYR-GCK          NMAKSDVTLNLSMLTLLQKNLQGTIFGGGNPHHDIPQLLSMYKAGRLNLD
Mvan_5164|M.vanbaalenii_PYR-1       NMASSEVTMNLSMLTLLQKNLQGTIFGGGNPHHDIPQLLSMYKAGRLNLD
MSMEG_5866|M.smegmatis_MC2_155      SMLDTNANINLAMLTLLQKNLQGTIFGGGNPHHDIPQLLSMYKAGKLNLD
TH_1254|M.thermoresistible__bu      SLLDTQVNLNLSMLTLLQKNLQGTIFGGGNPHHDIPQLLSMYKAGKLNLD
MMAR_4935|M.marinum_M               SLLDTQVNLNLAMLTLMQKNLQGTIFGGGNPQYDIPQLLSMYKARKLNID
MUL_0470|M.ulcerans_Agy99           SLLDTQVNLNLAMLTLMQKNLQGTIFGGGNPQYDIPHLLSMYKARNLNID
MAV_0705|M.avium_104                SLLDTNVTLNLAMLTLMQKNLQGTIFGGGNPQYDIPQLLSMYKAGKLNLD
Mb0784c|M.bovis_AF2122/97           SLVDTQVTLNLAMLTLLQKNIQGTIFGGGNPHYDIPKLLSMYKAGKLNLD
Rv0761c|M.tuberculosis_H37Rv        SLVDTQVTLNLAMLTLLQKNIQGTIFGGGNPHYDIPKLLSMYKAGKLNLD
MAB_4560|M.abscessus_ATCC_1997      AMVDVDVKFNLFLFTMLQKTLKGNIFGGGTTHTETPRLVGLYKQGLLKID
MLBr_01784|M.leprae_Br4923          -TPDMRLDMPLLDFFSHGGSLKSSWYGDCLPERDFPTLVDLYLQGRLPLG
                                       .    : *  :     .::.. :*.  .. : * *:.:*    * :.

Mflv_1593|M.gilvum_PYR-GCK          DMVTRQYKLEQINDGYKDMLEGKNIRGVIRYTDADR
Mvan_5164|M.vanbaalenii_PYR-1       DMVTRQYKLEQINEGYKDMLEGKNIRGVIRYTDADR
MSMEG_5866|M.smegmatis_MC2_155      DMVTRQYRLEQINDGYQDMLEGRNIRGVIRYTDADR
TH_1254|M.thermoresistible__bu      DMVTRQYKLEQINEGYQDMLEGRNIRGVIRYTDDDR
MMAR_4935|M.marinum_M               DMITRQYRLEQINEGYQDMIDGKNIRGVIRFTDADR
MUL_0470|M.ulcerans_Agy99           DMITRQYRLEQINEGYQDMIDGKNIRGVIRFTDADR
MAV_0705|M.avium_104                DMITRQYRLEQINDGYQDMLDGKNIRGVIRYTDADR
Mb0784c|M.bovis_AF2122/97           DMVTTAYKLEQINDGYQDMLNGKNIRGVIRYTDDDR
Rv0761c|M.tuberculosis_H37Rv        DMVTTAYKLEQINDGYQDMLNGKNIRGVIRYTDDDR
MAB_4560|M.abscessus_ATCC_1997      EMITSTYSLEQINEGYQDMLDGKNIRGVIKYTEADW
MLBr_01784|M.leprae_Br4923          KFVSERIGLGDVEEAFHKIHGGKVLRSVVML-----
                                    .:::    * ::::.::.:  *: :*.*: