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M. thermoresistible (build 8) TH_3905 (-)

annotation: Formyl-CoA transferase
coordinates: 1811002 - 1812207
length: 402

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3905--100% (402)Formyl-CoA transferase
M. thermoresistible (build 8)TH_3339-e-10547.74% (398) PUTATIVE putative L-carnitine dehydratase/bile acid-inducible
M. thermoresistible (build 8)TH_2997-7e-5534.71% (412) PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1897-2e-5133.58% (402) hypothetical protein Mb1897
M. gilvum PYR-GCKMflv_4465-0.085.43% (398) Formyl-CoA transferase
M. tuberculosis H37RvRv1866-2e-5133.58% (402) hypothetical protein Rv1866
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4651c-0.082.21% (399) putative L-carnitine dehydratase
M. marinum MMMAR_1494-0.083.04% (401) hypothetical protein MMAR_1494
M. avium 104MAV_4024-0.083.88% (397) caib/baif family protein
M. smegmatis MC2 155MSMEG_2073-0.086.40% (397) CAIB/BAIF family protein
M. ulcerans Agy99MUL_2446-0.082.54% (401) hypothetical protein MUL_2446
M. vanbaalenii PYR-1Mvan_1895-0.085.93% (398) L-carnitine dehydratase/bile acid-inducible protein F

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4465|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155      --------------------------------------------------
TH_3905|M.thermoresistible__bu      --------------------------------------------------
MMAR_1494|M.marinum_M               --------------------------------------------------
MUL_2446|M.ulcerans_Agy99           --------------------------------------------------
MAV_4024|M.avium_104                --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1897|M.bovis_AF2122/97            MVTRLLADLGADVLKVQPPGGSPGRHVRPTLAGTSIGFAMHNANKRSAVL
Rv1866|M.tuberculosis_H37Rv         MVTRLLADLGADVLKVEPPGGSPGRHVRPTLAGTSIGFAMHNANKRSAVL
                                                                                      

Mflv_4465|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155      --------------------------------------------------
TH_3905|M.thermoresistible__bu      --------------------------------------------------
MMAR_1494|M.marinum_M               --------------------------------------------------
MUL_2446|M.ulcerans_Agy99           --------------------------------------------------
MAV_4024|M.avium_104                --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1897|M.bovis_AF2122/97            NPLDESDRRRFLDLAASADIVVDCGLPGQAAAYGASCAELADRYRHLVAL
Rv1866|M.tuberculosis_H37Rv         NPLDESDRRRFLDLAASADIVVDCGLPGQAAAYGASCAELADRYRHLVAL
                                                                                      

Mflv_4465|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155      --------------------------------------------------
TH_3905|M.thermoresistible__bu      --------------------------------------------------
MMAR_1494|M.marinum_M               --------------------------------------------------
MUL_2446|M.ulcerans_Agy99           --------------------------------------------------
MAV_4024|M.avium_104                --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1897|M.bovis_AF2122/97            SITDFGAAGPRSSWRATDPVLYAMSGALSRSGPTAGTPVLPPDGIASATA
Rv1866|M.tuberculosis_H37Rv         SITDFGAAGPRSSWRATDPVLYAMSGALSRSGPTAGTPVLPPDGIASATA
                                                                                      

Mflv_4465|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155      --------------------------------------------------
TH_3905|M.thermoresistible__bu      --------------------------------------------------
MMAR_1494|M.marinum_M               --------------------------------------------------
MUL_2446|M.ulcerans_Agy99           --------------------------------------------------
MAV_4024|M.avium_104                --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1897|M.bovis_AF2122/97            AVQAAWAVLVAYFNRLRCGTGDYIDFSRFDAVVMALDPPFGAHGQVAAGI
Rv1866|M.tuberculosis_H37Rv         AVQAAWAVLVAYFNRLRCGTGDYIDFSRFDAVVMALDPPFGAHGQVAAGI
                                                                                      

Mflv_4465|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155      --------------------------------------------------
TH_3905|M.thermoresistible__bu      --------------------------------------------------
MMAR_1494|M.marinum_M               --------------------------------------------------
MUL_2446|M.ulcerans_Agy99           --------------------------------------------------
MAV_4024|M.avium_104                --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1897|M.bovis_AF2122/97            RSTGRWRGRPKNQDAYPIYPCRDGYVRFCVMAPRQWRGLRRWLGEPEDFQ
Rv1866|M.tuberculosis_H37Rv         RSTGRWRGRPKNQDAYPIYPCRDGYVRFCVMAPRQWRGLRRWLGEPEDFQ
                                                                                      

Mflv_4465|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155      --------------------------------------------------
TH_3905|M.thermoresistible__bu      --------------------------------------------------
MMAR_1494|M.marinum_M               --------------------------------------------------
MUL_2446|M.ulcerans_Agy99           --------------------------------------------------
MAV_4024|M.avium_104                --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1897|M.bovis_AF2122/97            DPKYDVIGARLAAWPQISVLVAKLCAEKTMKELVAAGQALGVPITAVLTP
Rv1866|M.tuberculosis_H37Rv         DPKYDVIGARLAAWPQISVLVAKLCAEKTMKELVAAGQALGVPITAVLTP
                                                                                      

Mflv_4465|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155      --------------------------------------------------
TH_3905|M.thermoresistible__bu      --------------------------------------------------
MMAR_1494|M.marinum_M               --------------------------------------------------
MUL_2446|M.ulcerans_Agy99           --------------------------------------------------
MAV_4024|M.avium_104                --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199      --------------------------------------------------
Mb1897|M.bovis_AF2122/97            SRILASEHFQAVGAITDAELVPGVRTGVPTGYFVVDGKRAGFRTPAPAAG
Rv1866|M.tuberculosis_H37Rv         SRILASEHFQAVGAITDAELVPGVRTGVPTGYFVVDGKRAGFRTPAPAAG
                                                                                      

Mflv_4465|M.gilvum_PYR-GCK          ---------------MTTG----PLDGIRVIEVGTLISGPFAGRLLGDMG
Mvan_1895|M.vanbaalenii_PYR-1       ---------------MTTG----PLDGIRVIEVGTLISGPFAGRLLGDMG
MSMEG_2073|M.smegmatis_MC2_155      ---------------MTAG----PLDGVRVLELGTLISGPFAGRLLGDMG
TH_3905|M.thermoresistible__bu      --------------VTVTG----PLDGIRVLELGTLIAGPFAGRLLGDMG
MMAR_1494|M.marinum_M               ---------------MTEP---GALDGIRVLELGTLIAGPFAGRLLGDMG
MUL_2446|M.ulcerans_Agy99           ---------------MTEP---GALDGIRVLELGTLIAGPFAGRLLGDMG
MAV_4024|M.avium_104                ---------------MSAAGAAGPLDGIRVLELGTLIAGPFAGRLLGDMG
MAB_4651c|M.abscessus_ATCC_199      ---------------MTG-----ALDGIRVLELGTLIAGPFAGRLLGDMG
Mb1897|M.bovis_AF2122/97            QDEPRWLADPAPVPPPSGRVGGYPFEGLRILDLGIIVAGGELSRLFGDLG
Rv1866|M.tuberculosis_H37Rv         QDEPRWLADPAPVPPPSGRVGGYPFEGLRILDLGIIVAGGELSRLFGDLG
                                                           .::*:*::::* :::*   .**:**:*

Mflv_4465|M.gilvum_PYR-GCK          AEVIKVEPPGAPDPLRTWGQAELDGHHFFWTVHARNKKAVTLNLRVPEGR
Mvan_1895|M.vanbaalenii_PYR-1       AEVIKIEPPGAPDPLRTWGQAELDGHHFFWTVHARNKKAVTLNLRVPEGR
MSMEG_2073|M.smegmatis_MC2_155      AEVIKIELPSAPDPLRTWGQAELDGHHFFWTVHARNKKAVTLDLRKPKGR
TH_3905|M.thermoresistible__bu      AEVIKIELPGAPDPLRTWGQAELDGHHFFWTVHARNKKAITLNLREPAGR
MMAR_1494|M.marinum_M               ADVIKVEAPGAPDPLRTWGQAEVDGHHVFWTVHARNKRAITLDLRRPQGR
MUL_2446|M.ulcerans_Agy99           ADVIKVEAPGAPDPLRTWGQAEVDGHHVFWTVHARNKRAITLDLRRPQGR
MAV_4024|M.avium_104                ADVIKVELPRAPDPLRTWGQAEVDGHHVFWTVHARNKRAITLDLRHPRGR
MAB_4651c|M.abscessus_ATCC_199      AEVLKIEPPGAPDPLRTWGQAEVDGHHVFWTVHARNKKAITLDLRTEAGR
Mb1897|M.bovis_AF2122/97            AEVIKVESADHPDGLRQTRVGDAMSESFAWTH--RNHLALGLDLRNSEGK
Rv1866|M.tuberculosis_H37Rv         AEVIKVESADHPDGLRQTRVGDAMSESFAWTH--RNHLALGLDLRNSEGK
                                    *:*:*:* .  ** **    .:  .. . **   **: *: *:**   *:

Mflv_4465|M.gilvum_PYR-GCK          DLFLDLVERSDVIVENFRPGTLEKWNLGYDVLRERNRGIILVRVSGYGQT
Mvan_1895|M.vanbaalenii_PYR-1       ELFLDLVERSDVIVENFRPGTLEKWGLGYDVLRERNRGIILVRVSGYGQT
MSMEG_2073|M.smegmatis_MC2_155      ELFLELVDRSDIIVENFRPGTLEKWDLGYDVLRQHNKGVILVRVSGYGQT
TH_3905|M.thermoresistible__bu      DVFLELVERSDIVVENFRPGTLERWDLGYDVLRSHNNRVILVRVSGYGQT
MMAR_1494|M.marinum_M               ELFLELVDKSDIVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQT
MUL_2446|M.ulcerans_Agy99           ELFLELVDKSDIVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQT
MAV_4024|M.avium_104                ELFCELVEKSDIVVENFRPGTLEKWNLGYDVLCERNPGIILVRVSGYGQT
MAB_4651c|M.abscessus_ATCC_199      ALFLDLVDKSDVIVENFRPGTLERWGLGYDVLAQRNKGIILVRVSGYGQT
Mb1897|M.bovis_AF2122/97            AIFGRLVAESDAVFANFKPGTLTSLGFSYDVLHAFNPRIVLAGSSAFGNR
Rv1866|M.tuberculosis_H37Rv         AIFGRLVAESDAVFANFKPGTLTSLGFSYDVLHAFNPRIVLAGSSAFGNR
                                     :*  ** .** :. **:****   .:.****   *  ::*.  *.:*: 

Mflv_4465|M.gilvum_PYR-GCK          GPDAHKAGYASVAEAASGLRHMNGFPGGPPPR-------LALSLGDSLAG
Mvan_1895|M.vanbaalenii_PYR-1       GPDAHKAGYASVAEAASGLRHMNGFPGGPPPR-------LALSLGDSLAG
MSMEG_2073|M.smegmatis_MC2_155      GPEAGKAGYASVAEAASGLRHMNGFPGGPPPR-------LALSLGDSLAG
TH_3905|M.thermoresistible__bu      GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDTLAG
MMAR_1494|M.marinum_M               GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDSLAG
MUL_2446|M.ulcerans_Agy99           GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDSLAG
MAV_4024|M.avium_104                GPDAAKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDSLAG
MAB_4651c|M.abscessus_ATCC_199      GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------MALSIGDTLAG
Mb1897|M.bovis_AF2122/97            GPWSTRMGYGPLVRAATGVTRVWTSDEAQPDNSRHPFYDATTIFPDHVVG
Rv1866|M.tuberculosis_H37Rv         GPWSTRMGYGPLVRAATGVTRVWTSDEAQPDNSRHPFYDATTIFPDHVVG
                                    ** : : **..:..**:*: ::     . * .        :  : * :.*

Mflv_4465|M.gilvum_PYR-GCK          MFAAQGALAALYRRSVTGEGQIVDAALTESCLAVQESTIPDYDVGGVVRG
Mvan_1895|M.vanbaalenii_PYR-1       MFAAQGALAALYRRSVTGDGQVVDAALTESCLAVQESTIPDYDVGGVVRG
MSMEG_2073|M.smegmatis_MC2_155      MFAAQGALAALYRRSVTGEGQVVDTALTESCLAIQESTIPDYDVGGVVRG
TH_3905|M.thermoresistible__bu      MFAAQGAMAALYRRTVTGEGQVVDAALTEACLAVQESTIPDYDIGGVVRG
MMAR_1494|M.marinum_M               MFGAQGALAALYRRSVTGTGQVVDVALTESCLALQESTISDYDVGGVVRG
MUL_2446|M.ulcerans_Agy99           MFGPQGALAALYRRSVTGTGQVVDVALTESCLALQESTISDYDVGGVVRG
MAV_4024|M.avium_104                MFGAQGALAALYRRSVTGRGQVVDVALTESCLAVQESTIPDYDVGGVVRG
MAB_4651c|M.abscessus_ATCC_199      MFAAQGALAALYRRTVTGRGQVVDAALTESCLAVQESTIPDYDVGRVVRG
Mb1897|M.bovis_AF2122/97            RVGALLALAALIHRDRTGGGAHVHISQAEVVVNQLDTMFVAEAAR--ATD
Rv1866|M.tuberculosis_H37Rv         RVGALLALAALIHRDRTGGGAHVHISQAEVVVNQLDTMFVAEAAR--ATD
                                     ...  *:*** :*  ** *  *. : :*  :   :: :        . .

Mflv_4465|M.gilvum_PYR-GCK          PSGTRLEGIAPSNIYPTADGSWVVIAANQDTVFRRLCAAMGQPELATDER
Mvan_1895|M.vanbaalenii_PYR-1       PSGTRLEGIAPSNIYPTADGSWVVIAANQDTVFRRLCAAMGQPELATDER
MSMEG_2073|M.smegmatis_MC2_155      PSGTRLEGIAPSNIYQSANGSWVVIAANQDTVFRRLCAAMGRPELATDER
TH_3905|M.thermoresistible__bu      PSGTRLEGIAPSNIYRSADGSWVVIAANQDTVFRRLCAAMGRPELATDDR
MMAR_1494|M.marinum_M               PSGTRLEGIAPSNIYRSADESWVVIAANQDTVFTRLCQAMGCPELATDDR
MUL_2446|M.ulcerans_Agy99           PSGTRLKGIAPSNIYRSADESWVVIAANQDTVFTRLCQAMGCPELATDDR
MAV_4024|M.avium_104                PSGTRLEGIAPSNIYRSADGSWVVIAANQDTVFARLCKAMGRAELATDER
MAB_4651c|M.abscessus_ATCC_199      PSGTRLEGIAPSNIYQSADGSWVVIAANQDTVFRRLCEAMGRPELSSDAR
Mb1897|M.bovis_AF2122/97            VAEIHPDTSVHAVYPCAGDDEWCVISIRSDDEWRRATSVFGQPELANDPR
Rv1866|M.tuberculosis_H37Rv         VAEIHPDTSVHAVYPCAGDDEWCVISIRSDDEWRRATSVFGQPELANDPR
                                     :  : .  . :    :.: .* **: ..*  : *   .:* .**:.* *

Mflv_4465|M.gilvum_PYR-GCK          FADHVARGRNQDEIDKIIGGWAAQRQPDEIISTLSEAGVISGPINTVAEV
Mvan_1895|M.vanbaalenii_PYR-1       FANHVARGRNQDELDKIIGAWAAERQPADIIATLSEAGVISGPINTVAEV
MSMEG_2073|M.smegmatis_MC2_155      FSDHLARGRNQDELDKIIGDWAAQRQPDEIISTLSDAGVIAGPINTVAEV
TH_3905|M.thermoresistible__bu      FATHTARGRNQDELDKIIADWAAERAPGEIIDTLNAAGVIAGPINTVAEV
MMAR_1494|M.marinum_M               FATHRARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEV
MUL_2446|M.ulcerans_Agy99           FATHRARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEV
MAV_4024|M.avium_104                FATHVARGRIQDELDGIIGEWAAQRQPDEIIETLSAAGVIAGPINTVAEV
MAB_4651c|M.abscessus_ATCC_199      FANHVARGRNQDDLDAIIAQWAAQRLPTDIIDVLSAAGVIAGPINTVADV
Mb1897|M.bovis_AF2122/97            FGASRSRVANRSELVAAVSAWTSTRTPVQAAGALQAAGVAAGPMNRPSDI
Rv1866|M.tuberculosis_H37Rv         FGASRSRVANRSELVAAVSAWTSTRTPVQAAGALQAAGVAAGPMNRPSDI
                                    *.   :*   :.::   :. *:: * * :   .*. *** :**:*  :::

Mflv_4465|M.gilvum_PYR-GCK          VEDPQLQARGMIADHWDERIGRNVKGPGVVPVLSETPGTIRSAGSARPGQ
Mvan_1895|M.vanbaalenii_PYR-1       VKDPQLQARGMIADHWDERIGRNVKGPGVVPVLSETPGTIRSAGSSRPGE
MSMEG_2073|M.smegmatis_MC2_155      VNDPQLQARGMIADHWDERVQRNIKGPGVVPVLSESPGTIRNAGSARPGQ
TH_3905|M.thermoresistible__bu      VEDPQLRARGMIADHFDERIGRNVKGPGVVPVLSESPGTIRNAGPARPGQ
MMAR_1494|M.marinum_M               VKDRQLRARGMLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQ
MUL_2446|M.ulcerans_Agy99           VKDRQLRARGMLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQ
MAV_4024|M.avium_104                VNDPQLRARDMLVEHYDERLRRNVLGPGIVPVLSESPGRVRNAGPARPGQ
MAB_4651c|M.abscessus_ATCC_199      VQDPQLKAREMLVEHFDERLGRSVLGPGVVPVLSESPGGVRNAGPARPGQ
Mb1897|M.bovis_AF2122/97            LEDPQLIERNLFRDMVHPLIARPLPAETGPAPFRHIPQAPQRPAP-LPGQ
Rv1866|M.tuberculosis_H37Rv         LEDPQLIERNLFRDMVHPLIARPLPAETGPAPFRHIPQAPQRPAP-LPGQ
                                    ::* **  * :: :  .  : * : .    . : . *   : ...  **:

Mflv_4465|M.gilvum_PYR-GCK          HNDEIYRDLLGRSAAELDKLQEEGVL-------
Mvan_1895|M.vanbaalenii_PYR-1       HNDEIYRGLLGKTDAELERLRAGGVL-------
MSMEG_2073|M.smegmatis_MC2_155      HNDEIYTGLLGHTADELQTLHDEGVL-------
TH_3905|M.thermoresistible__bu      HNEEIYTGLLGKTAAELRQLRAQGVI-------
MMAR_1494|M.marinum_M               HNDDVYIGLLGKSIEELEQLRAEEVL-------
MUL_2446|M.ulcerans_Agy99           HNDDVYIGLLGKSIEELEQLRAVEVL-------
MAV_4024|M.avium_104                HNDEVYRGLLGKTAEELEELRAQEVL-------
MAB_4651c|M.abscessus_ATCC_199      DNDDVYVGLLGKSAQDIERLRAEGVL-------
Mb1897|M.bovis_AF2122/97            DSVQICRKLLGMTADETERLINERVMFGPAVTA
Rv1866|M.tuberculosis_H37Rv         DSVQICRKLLGMTADETERLINERVMFGPAVTA
                                    .. ::   *** :  :   *    *: