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MTEPGALDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEAPGAPDPLRTWGQAEVDGHHVFWTVHARNKR AITLDLRRPQGRELFLELVDKSDIVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQTGPDAHKAG YASVAEAASGLRHLNGFPGGPPPRLALSLGDSLAGMFGPQGALAALYRRSVTGTGQVVDVALTESCLALQ ESTISDYDVGGVVRGPSGTRLKGIAPSNIYRSADESWVVIAANQDTVFTRLCQAMGCPELATDDRFATHR ARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEVVKDRQLRARGMLVEHYDERIGRNVL GPGIVPALSESPGQVRSAGPARPGQHNDDVYIGLLGKSIEELEQLRAVEVL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2446 | - | - | 100% (401) | hypothetical protein MUL_2446 |
| M. ulcerans Agy99 | MUL_0328 | - | 2e-47 | 32.34% (402) | acyl-CoA transferase |
| M. ulcerans Agy99 | MUL_2621 | - | 4e-42 | 32.24% (397) | acyl-CoA transferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1897 | - | 2e-49 | 33.42% (404) | hypothetical protein Mb1897 |
| M. gilvum PYR-GCK | Mflv_4465 | - | 0.0 | 82.12% (397) | Formyl-CoA transferase |
| M. tuberculosis H37Rv | Rv1866 | - | 2e-49 | 33.42% (404) | hypothetical protein Rv1866 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4651c | - | 0.0 | 82.62% (397) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_1494 | - | 0.0 | 99.25% (401) | hypothetical protein MMAR_1494 |
| M. avium 104 | MAV_4024 | - | 0.0 | 90.18% (397) | caib/baif family protein |
| M. smegmatis MC2 155 | MSMEG_2073 | - | 0.0 | 81.86% (397) | CAIB/BAIF family protein |
| M. thermoresistible (build 8) | TH_3905 | - | 0.0 | 82.54% (401) | PUTATIVE Formyl-CoA transferase |
| M. vanbaalenii PYR-1 | Mvan_1895 | - | 0.0 | 82.87% (397) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 MVTRLLADLGADVLKVQPPGGSPGRHVRPTLAGTSIGFAMHNANKRSAVL
Rv1866|M.tuberculosis_H37Rv MVTRLLADLGADVLKVEPPGGSPGRHVRPTLAGTSIGFAMHNANKRSAVL
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 NPLDESDRRRFLDLAASADIVVDCGLPGQAAAYGASCAELADRYRHLVAL
Rv1866|M.tuberculosis_H37Rv NPLDESDRRRFLDLAASADIVVDCGLPGQAAAYGASCAELADRYRHLVAL
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 SITDFGAAGPRSSWRATDPVLYAMSGALSRSGPTAGTPVLPPDGIASATA
Rv1866|M.tuberculosis_H37Rv SITDFGAAGPRSSWRATDPVLYAMSGALSRSGPTAGTPVLPPDGIASATA
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 AVQAAWAVLVAYFNRLRCGTGDYIDFSRFDAVVMALDPPFGAHGQVAAGI
Rv1866|M.tuberculosis_H37Rv AVQAAWAVLVAYFNRLRCGTGDYIDFSRFDAVVMALDPPFGAHGQVAAGI
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 RSTGRWRGRPKNQDAYPIYPCRDGYVRFCVMAPRQWRGLRRWLGEPEDFQ
Rv1866|M.tuberculosis_H37Rv RSTGRWRGRPKNQDAYPIYPCRDGYVRFCVMAPRQWRGLRRWLGEPEDFQ
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 DPKYDVIGARLAAWPQISVLVAKLCAEKTMKELVAAGQALGVPITAVLTP
Rv1866|M.tuberculosis_H37Rv DPKYDVIGARLAAWPQISVLVAKLCAEKTMKELVAAGQALGVPITAVLTP
MUL_2446|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1494|M.marinum_M --------------------------------------------------
MAV_4024|M.avium_104 --------------------------------------------------
Mflv_4465|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1895|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2073|M.smegmatis_MC2_155 --------------------------------------------------
TH_3905|M.thermoresistible__bu --------------------------------------------------
MAB_4651c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1897|M.bovis_AF2122/97 SRILASEHFQAVGAITDAELVPGVRTGVPTGYFVVDGKRAGFRTPAPAAG
Rv1866|M.tuberculosis_H37Rv SRILASEHFQAVGAITDAELVPGVRTGVPTGYFVVDGKRAGFRTPAPAAG
MUL_2446|M.ulcerans_Agy99 ---------------MTEP---GALDGIRVLELGTLIAGPFAGRLLGDMG
MMAR_1494|M.marinum_M ---------------MTEP---GALDGIRVLELGTLIAGPFAGRLLGDMG
MAV_4024|M.avium_104 ---------------MSAAGAAGPLDGIRVLELGTLIAGPFAGRLLGDMG
Mflv_4465|M.gilvum_PYR-GCK ---------------MTTG----PLDGIRVIEVGTLISGPFAGRLLGDMG
Mvan_1895|M.vanbaalenii_PYR-1 ---------------MTTG----PLDGIRVIEVGTLISGPFAGRLLGDMG
MSMEG_2073|M.smegmatis_MC2_155 ---------------MTAG----PLDGVRVLELGTLISGPFAGRLLGDMG
TH_3905|M.thermoresistible__bu --------------VTVTG----PLDGIRVLELGTLIAGPFAGRLLGDMG
MAB_4651c|M.abscessus_ATCC_199 ---------------MTG-----ALDGIRVLELGTLIAGPFAGRLLGDMG
Mb1897|M.bovis_AF2122/97 QDEPRWLADPAPVPPPSGRVGGYPFEGLRILDLGIIVAGGELSRLFGDLG
Rv1866|M.tuberculosis_H37Rv QDEPRWLADPAPVPPPSGRVGGYPFEGLRILDLGIIVAGGELSRLFGDLG
.::*:*::::* :::* .**:**:*
MUL_2446|M.ulcerans_Agy99 ADVIKVEAPGAPDPLRTWGQAEVDGHHVFWTVHARNKRAITLDLRRPQGR
MMAR_1494|M.marinum_M ADVIKVEAPGAPDPLRTWGQAEVDGHHVFWTVHARNKRAITLDLRRPQGR
MAV_4024|M.avium_104 ADVIKVELPRAPDPLRTWGQAEVDGHHVFWTVHARNKRAITLDLRHPRGR
Mflv_4465|M.gilvum_PYR-GCK AEVIKVEPPGAPDPLRTWGQAELDGHHFFWTVHARNKKAVTLNLRVPEGR
Mvan_1895|M.vanbaalenii_PYR-1 AEVIKIEPPGAPDPLRTWGQAELDGHHFFWTVHARNKKAVTLNLRVPEGR
MSMEG_2073|M.smegmatis_MC2_155 AEVIKIELPSAPDPLRTWGQAELDGHHFFWTVHARNKKAVTLDLRKPKGR
TH_3905|M.thermoresistible__bu AEVIKIELPGAPDPLRTWGQAELDGHHFFWTVHARNKKAITLNLREPAGR
MAB_4651c|M.abscessus_ATCC_199 AEVLKIEPPGAPDPLRTWGQAEVDGHHVFWTVHARNKKAITLDLRTEAGR
Mb1897|M.bovis_AF2122/97 AEVIKVESADHPDGLRQTRVGDAMSESFAWTH--RNHLALGLDLRNSEGK
Rv1866|M.tuberculosis_H37Rv AEVIKVESADHPDGLRQTRVGDAMSESFAWTH--RNHLALGLDLRNSEGK
*:*:*:* . ** ** .: .. . ** **: *: *:** *:
MUL_2446|M.ulcerans_Agy99 ELFLELVDKSDIVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQT
MMAR_1494|M.marinum_M ELFLELVDKSDIVVENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQT
MAV_4024|M.avium_104 ELFCELVEKSDIVVENFRPGTLEKWNLGYDVLCERNPGIILVRVSGYGQT
Mflv_4465|M.gilvum_PYR-GCK DLFLDLVERSDVIVENFRPGTLEKWNLGYDVLRERNRGIILVRVSGYGQT
Mvan_1895|M.vanbaalenii_PYR-1 ELFLDLVERSDVIVENFRPGTLEKWGLGYDVLRERNRGIILVRVSGYGQT
MSMEG_2073|M.smegmatis_MC2_155 ELFLELVDRSDIIVENFRPGTLEKWDLGYDVLRQHNKGVILVRVSGYGQT
TH_3905|M.thermoresistible__bu DVFLELVERSDIVVENFRPGTLERWDLGYDVLRSHNNRVILVRVSGYGQT
MAB_4651c|M.abscessus_ATCC_199 ALFLDLVDKSDVIVENFRPGTLERWGLGYDVLAQRNKGIILVRVSGYGQT
Mb1897|M.bovis_AF2122/97 AIFGRLVAESDAVFANFKPGTLTSLGFSYDVLHAFNPRIVLAGSSAFGNR
Rv1866|M.tuberculosis_H37Rv AIFGRLVAESDAVFANFKPGTLTSLGFSYDVLHAFNPRIVLAGSSAFGNR
:* ** .** :. **:**** .:.**** * ::*. *.:*:
MUL_2446|M.ulcerans_Agy99 GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDSLAG
MMAR_1494|M.marinum_M GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDSLAG
MAV_4024|M.avium_104 GPDAAKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDSLAG
Mflv_4465|M.gilvum_PYR-GCK GPDAHKAGYASVAEAASGLRHMNGFPGGPPPR-------LALSLGDSLAG
Mvan_1895|M.vanbaalenii_PYR-1 GPDAHKAGYASVAEAASGLRHMNGFPGGPPPR-------LALSLGDSLAG
MSMEG_2073|M.smegmatis_MC2_155 GPEAGKAGYASVAEAASGLRHMNGFPGGPPPR-------LALSLGDSLAG
TH_3905|M.thermoresistible__bu GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------LALSLGDTLAG
MAB_4651c|M.abscessus_ATCC_199 GPDAHKAGYASVAEAASGLRHLNGFPGGPPPR-------MALSIGDTLAG
Mb1897|M.bovis_AF2122/97 GPWSTRMGYGPLVRAATGVTRVWTSDEAQPDNSRHPFYDATTIFPDHVVG
Rv1866|M.tuberculosis_H37Rv GPWSTRMGYGPLVRAATGVTRVWTSDEAQPDNSRHPFYDATTIFPDHVVG
** : : **..:..**:*: :: . * . : : * :.*
MUL_2446|M.ulcerans_Agy99 MFGPQGALAALYRRSVTGTGQVVDVALTESCLALQESTISDYDVGGVVRG
MMAR_1494|M.marinum_M MFGAQGALAALYRRSVTGTGQVVDVALTESCLALQESTISDYDVGGVVRG
MAV_4024|M.avium_104 MFGAQGALAALYRRSVTGRGQVVDVALTESCLAVQESTIPDYDVGGVVRG
Mflv_4465|M.gilvum_PYR-GCK MFAAQGALAALYRRSVTGEGQIVDAALTESCLAVQESTIPDYDVGGVVRG
Mvan_1895|M.vanbaalenii_PYR-1 MFAAQGALAALYRRSVTGDGQVVDAALTESCLAVQESTIPDYDVGGVVRG
MSMEG_2073|M.smegmatis_MC2_155 MFAAQGALAALYRRSVTGEGQVVDTALTESCLAIQESTIPDYDVGGVVRG
TH_3905|M.thermoresistible__bu MFAAQGAMAALYRRTVTGEGQVVDAALTEACLAVQESTIPDYDIGGVVRG
MAB_4651c|M.abscessus_ATCC_199 MFAAQGALAALYRRTVTGRGQVVDAALTESCLAVQESTIPDYDVGRVVRG
Mb1897|M.bovis_AF2122/97 RVGALLALAALIHRDRTGGGAHVHISQAEVVVNQLDTMFVAEAAR--ATD
Rv1866|M.tuberculosis_H37Rv RVGALLALAALIHRDRTGGGAHVHISQAEVVVNQLDTMFVAEAAR--ATD
... *:*** :* ** * *. : :* : :: : . .
MUL_2446|M.ulcerans_Agy99 PSGTRLKGIAPSNIYRSADESWVVIAANQDTVFTRLCQAMGCPELATDDR
MMAR_1494|M.marinum_M PSGTRLEGIAPSNIYRSADESWVVIAANQDTVFTRLCQAMGCPELATDDR
MAV_4024|M.avium_104 PSGTRLEGIAPSNIYRSADGSWVVIAANQDTVFARLCKAMGRAELATDER
Mflv_4465|M.gilvum_PYR-GCK PSGTRLEGIAPSNIYPTADGSWVVIAANQDTVFRRLCAAMGQPELATDER
Mvan_1895|M.vanbaalenii_PYR-1 PSGTRLEGIAPSNIYPTADGSWVVIAANQDTVFRRLCAAMGQPELATDER
MSMEG_2073|M.smegmatis_MC2_155 PSGTRLEGIAPSNIYQSANGSWVVIAANQDTVFRRLCAAMGRPELATDER
TH_3905|M.thermoresistible__bu PSGTRLEGIAPSNIYRSADGSWVVIAANQDTVFRRLCAAMGRPELATDDR
MAB_4651c|M.abscessus_ATCC_199 PSGTRLEGIAPSNIYQSADGSWVVIAANQDTVFRRLCEAMGRPELSSDAR
Mb1897|M.bovis_AF2122/97 VAEIHPDTSVHAVYPCAGDDEWCVISIRSDDEWRRATSVFGQPELANDPR
Rv1866|M.tuberculosis_H37Rv VAEIHPDTSVHAVYPCAGDDEWCVISIRSDDEWRRATSVFGQPELANDPR
: : . . : :.: .* **: ..* : * .:* .**:.* *
MUL_2446|M.ulcerans_Agy99 FATHRARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEV
MMAR_1494|M.marinum_M FATHRARGRNQDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEV
MAV_4024|M.avium_104 FATHVARGRIQDELDGIIGEWAAQRQPDEIIETLSAAGVIAGPINTVAEV
Mflv_4465|M.gilvum_PYR-GCK FADHVARGRNQDEIDKIIGGWAAQRQPDEIISTLSEAGVISGPINTVAEV
Mvan_1895|M.vanbaalenii_PYR-1 FANHVARGRNQDELDKIIGAWAAERQPADIIATLSEAGVISGPINTVAEV
MSMEG_2073|M.smegmatis_MC2_155 FSDHLARGRNQDELDKIIGDWAAQRQPDEIISTLSDAGVIAGPINTVAEV
TH_3905|M.thermoresistible__bu FATHTARGRNQDELDKIIADWAAERAPGEIIDTLNAAGVIAGPINTVAEV
MAB_4651c|M.abscessus_ATCC_199 FANHVARGRNQDDLDAIIAQWAAQRLPTDIIDVLSAAGVIAGPINTVADV
Mb1897|M.bovis_AF2122/97 FGASRSRVANRSELVAAVSAWTSTRTPVQAAGALQAAGVAAGPMNRPSDI
Rv1866|M.tuberculosis_H37Rv FGASRSRVANRSELVAAVSAWTSTRTPVQAAGALQAAGVAAGPMNRPSDI
*. :* :.:: :. *:: * * : .*. *** :**:* :::
MUL_2446|M.ulcerans_Agy99 VKDRQLRARGMLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQ
MMAR_1494|M.marinum_M VKDRQLRARGMLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQ
MAV_4024|M.avium_104 VNDPQLRARDMLVEHYDERLRRNVLGPGIVPVLSESPGRVRNAGPARPGQ
Mflv_4465|M.gilvum_PYR-GCK VEDPQLQARGMIADHWDERIGRNVKGPGVVPVLSETPGTIRSAGSARPGQ
Mvan_1895|M.vanbaalenii_PYR-1 VKDPQLQARGMIADHWDERIGRNVKGPGVVPVLSETPGTIRSAGSSRPGE
MSMEG_2073|M.smegmatis_MC2_155 VNDPQLQARGMIADHWDERVQRNIKGPGVVPVLSESPGTIRNAGSARPGQ
TH_3905|M.thermoresistible__bu VEDPQLRARGMIADHFDERIGRNVKGPGVVPVLSESPGTIRNAGPARPGQ
MAB_4651c|M.abscessus_ATCC_199 VQDPQLKAREMLVEHFDERLGRSVLGPGVVPVLSESPGGVRNAGPARPGQ
Mb1897|M.bovis_AF2122/97 LEDPQLIERNLFRDMVHPLIARPLPAETGPAPFRHIPQAPQRPAP-LPGQ
Rv1866|M.tuberculosis_H37Rv LEDPQLIERNLFRDMVHPLIARPLPAETGPAPFRHIPQAPQRPAP-LPGQ
::* ** * :: : . : * : . . : . * : ... **:
MUL_2446|M.ulcerans_Agy99 HNDDVYIGLLGKSIEELEQLRAVEVL-------
MMAR_1494|M.marinum_M HNDDVYIGLLGKSIEELEQLRAEEVL-------
MAV_4024|M.avium_104 HNDEVYRGLLGKTAEELEELRAQEVL-------
Mflv_4465|M.gilvum_PYR-GCK HNDEIYRDLLGRSAAELDKLQEEGVL-------
Mvan_1895|M.vanbaalenii_PYR-1 HNDEIYRGLLGKTDAELERLRAGGVL-------
MSMEG_2073|M.smegmatis_MC2_155 HNDEIYTGLLGHTADELQTLHDEGVL-------
TH_3905|M.thermoresistible__bu HNEEIYTGLLGKTAAELRQLRAQGVI-------
MAB_4651c|M.abscessus_ATCC_199 DNDDVYVGLLGKSAQDIERLRAEGVL-------
Mb1897|M.bovis_AF2122/97 DSVQICRKLLGMTADETERLINERVMFGPAVTA
Rv1866|M.tuberculosis_H37Rv DSVQICRKLLGMTADETERLINERVMFGPAVTA
.. :: *** : : * *: