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SLEQAVAAPYATRQLADLGARVIKVERPQGGDFARGYDRTVHGESSYFVWLNRGKESLTVDLKQPEGRRI VERLLEGADVLVQNLAPGAAARMGLDTESVARAHPRTITATISGYGQDGPWRDRKAYDLLVQAEAGLLSV TGSPAEVARTGVSIADIAAGMFAFSGILTALYTRATTGAVRPVSVSLFDALVEWMSQPLYYGRYGGKAPP RTGARHPTIAPYGPVTAGDGGTVLLGVQNSAEWLRFCEIVLERRDLVDEPRFATNPDRVAHRDELESIIT TVAARLSAEELEARLQSAGVAHARMNGVDHLWLHPVLVGRDRWHEIQTPGGPAAALPPPAGLAGVDPVIG DVPALGEHSRKILHELGYSAQATDELIAAGVTTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2651 | - | - | 100% (385) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. avium 104 | MAV_1892 | - | e-156 | 70.83% (384) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. avium 104 | MAV_4024 | - | 3e-41 | 30.71% (394) | caib/baif family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 2e-32 | 30.10% (382) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_2443 | - | 3e-92 | 45.48% (387) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv3272 | - | 2e-32 | 30.10% (382) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0824 | - | 8e-45 | 33.88% (363) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_0311 | - | 4e-38 | 32.98% (379) | hypothetical protein MMAR_0311 |
| M. smegmatis MC2 155 | MSMEG_1992 | - | 1e-116 | 56.10% (369) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. thermoresistible (build 8) | TH_2496 | - | 1e-92 | 45.97% (385) | PUTATIVE L-carnitine dehydratase/bile acid-inducible protein F |
| M. ulcerans Agy99 | MUL_4811 | - | 1e-38 | 32.98% (379) | hypothetical protein MUL_4811 |
| M. vanbaalenii PYR-1 | Mvan_4208 | - | 4e-88 | 44.19% (387) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2651|M.avium_104 ----------------------------MSLEQAVAAPYATRQLADLGAR
MSMEG_1992|M.smegmatis_MC2_155 -----------MHPQANGKSLPLSGITVLSLEHAVAAPFATRQLADLGAR
Mflv_2443|M.gilvum_PYR-GCK ------------MTASQ-SAGPLAGVTVVAMEQAVAAPMCTRVLADFGAR
Mvan_4208|M.vanbaalenii_PYR-1 ------------MSSSQPSAAPLAGVTVVAMEQAVAAPMCTRVLADFGAR
TH_2496|M.thermoresistible__bu -----------MAESEHADPAPLAGITVVALEQAVSAPMCTRVLADFGAR
MMAR_0311|M.marinum_M MSNCGSDCDSSLGAGAGKRTGPLSGVRVVDLTAMVMGPYCTQIMADMGAD
MUL_4811|M.ulcerans_Agy99 -----------MGAGAGNRTGPLSGVRVVDLTAMVMGPYCTQIMADMGAD
Mb3300|M.bovis_AF2122/97 -------------MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAE
Rv3272|M.tuberculosis_H37Rv -------------MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAE
MAB_0824|M.abscessus_ATCC_1997 -----------------MTAAALDGLLVVDFSRVLAGPYATMMLGDFGAE
: : : .* . : *:**
MAV_2651|M.avium_104 VIKVERPQGGDFARGYDRTVHG---ESSYFVWLNRGKESLTVDLKQPEGR
MSMEG_1992|M.smegmatis_MC2_155 VIKVERPGSGDFARQYDDSVNG---ESSYFVWLNRSKESIALDVKSEHGH
Mflv_2443|M.gilvum_PYR-GCK IIKVENPNGGDFARAYDDVVNGPGGLAAHFVWSNRGKESVTLNTKSPAGL
Mvan_4208|M.vanbaalenii_PYR-1 IIKVENPNGGDFARDYDDVVNGPGGLAAHFVWSNRGKESVTLNTKTAGGL
TH_2496|M.thermoresistible__bu VIKVENPDGGDFARHYDDVVKG---QAAHFVWANRGKESVTLNLKSEAGM
MMAR_0311|M.marinum_M VIKIEPPQGDDTRYVSVGPAAG---MSGVFVNVNRGKRSAVIDLKSDSGQ
MUL_4811|M.ulcerans_Agy99 VIKIEPPQGDDTRYVSVGPAAG---MSGVFVNVNRGKRSAVIDLKSDSGQ
Mb3300|M.bovis_AF2122/97 VIKVEAPGGEAARQITSVLPGRPP-LATYFLPNNRGKKSVTVDLTTEQAK
Rv3272|M.tuberculosis_H37Rv VIKVEAPGGEAARQITSVLPGRPP-LATYFLPNNRGKKSVTVDLTTEQAK
MAB_0824|M.abscessus_ATCC_1997 VIKIERPVLGDDTRQWGPPYDSDG-QATYFNSVNRNKQSVVLDLTSPDGQ
:**:* * : * **.*.* .:: . .
MAV_2651|M.avium_104 RIVERLLEGADVLVQNLAPGAAARMGLDTESVARAHPRTITATISGYGQD
MSMEG_1992|M.smegmatis_MC2_155 RVLHELADRADVVVQNLGPGAAARLGLAAEDIRAKDPRKIVVSVTGWGST
Mflv_2443|M.gilvum_PYR-GCK EVLHRLLDRADAFVSNLAPGATARLGLSPADLAERHPQVIPVEIDGYGPG
Mvan_4208|M.vanbaalenii_PYR-1 DLLHRLLDRADAFVSNLAPGATARLGVAPADLAARHPRVIPVEIDGYGPG
TH_2496|M.thermoresistible__bu AVLHRLLDEADVLVSNLAPGALARMGLAADDLKTSHPRVLPVQIDGYGAG
MMAR_0311|M.marinum_M AAVRALIEGADVFIHSMRAKAIARLGLSYPEVAAINPAIVYTNCYGYGRR
MUL_4811|M.ulcerans_Agy99 AAVRALIEGADVFIHSMRAKAIARLGLSYPEVAAINPAIVYTNCYGYGRR
Mb3300|M.bovis_AF2122/97 QQMLRLADTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGN
Rv3272|M.tuberculosis_H37Rv QQMLRLADTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGN
MAB_0824|M.abscessus_ATCC_1997 HRARELAGRADVVVENFRAGTMEKFGLGYQSLKQLNPGLIYCAITGFG-R
* **..: : . : ::*: .: .* : .:*
MAV_2651|M.avium_104 GPWRDRKAYDLLVQAEAGLLSVTG-SPAEVARTGVSIADIAAGMFAFSGI
MSMEG_1992|M.smegmatis_MC2_155 GPWADRKAYDLLVQCETGLVSLTG-TPDEVAKVGVSIADIAAGMYAFSGI
Mflv_2443|M.gilvum_PYR-GCK GPISHKRAYDLLVQAESGSCAVTG-YPGMPAKPGPAVADFTSGLYAAMSI
Mvan_4208|M.vanbaalenii_PYR-1 GPLSHKRAYDLLVQAESGSCAVTG-YPGMPAKPGPAVADFSTGLYAAISI
TH_2496|M.thermoresistible__bu GPISHKRAYDLLIQAESGACAVTG-YPGMPAKPGPPVADISTGLYAALSV
MMAR_0311|M.marinum_M GPNRDLPAYDDTIQAACGLPSVQEQLTGEPSYVGTIMADKVAGLTALYAT
MUL_4811|M.ulcerans_Agy99 GPNRDLPAYDDTIQAACGLPSVQEQLTGEPSYVGTIMADKVAGLTALYAT
Mb3300|M.bovis_AF2122/97 GPHGSRPGIDLVVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAV
Rv3272|M.tuberculosis_H37Rv GPHGSRPGIDLVVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAV
MAB_0824|M.abscessus_ATCC_1997 GAGADLPGYDLLVQAVGGLMSVTGPDAAHPSKVGVALVDVLTALHALSGI
*. . * : . * : :.* :. .
MAV_2651|M.avium_104 LTALYTRATT-----GAVRPVSVSLFDALVEWMSQPLYYGRYGGKAPPRT
MSMEG_1992|M.smegmatis_MC2_155 LAALYRREIT-----GEGAVIEVSLFEALAEWVGQPAHFTAGAGRQPGRF
Mflv_2443|M.gilvum_PYR-GCK VSLLYGRATR--PEPGPAPHVELSLFDVMTDVMGYALTYTQHSGIDQEPL
Mvan_4208|M.vanbaalenii_PYR-1 LALLYGRARH--PGSAPAPSVELSLFDVMTDVMGYALTYTQHSGIDQEPL
TH_2496|M.thermoresistible__bu MALLYGRDRRDRATPGPVPAVAVSLFDTMTDIMGYQLTYTQHSGVDQQPL
MMAR_0311|M.marinum_M MMALFHRERT-----GQGQEVEIGMFEAVASFMLVEHANGAMFDPPLGPA
MUL_4811|M.ulcerans_Agy99 MMALFHRERT-----GQGQEVEIGMFEAVASFMLVEHANGAMFDPPLGPA
Mb3300|M.bovis_AF2122/97 LAALLHRERN-----GVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPK
Rv3272|M.tuberculosis_H37Rv LAALLHRERN-----GVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPK
MAB_0824|M.abscessus_ATCC_1997 LAALSYRDRT-----GQGQRVDTDLMSVLLSSLVNQASGYLGAGVVPEAL
: * * . : : ..
MAV_2651|M.avium_104 GARHP----------TIAPYGPVTAGDGGTVLLGVQNSAEWLRFCEIVLE
MSMEG_1992|M.smegmatis_MC2_155 GAQHA----------TIAPYGPFEAADGHTLLIAIQNEPEWARFCTTVLG
Mflv_2443|M.gilvum_PYR-GCK GVGSP----------AVAPYGAFPTRDGQTVVLGTTNDREWQRVAREIID
Mvan_4208|M.vanbaalenii_PYR-1 GVGSP----------AVAPYGAFPTRDGQTVVLGTTNDREWQRVAREIID
TH_2496|M.thermoresistible__bu GMSSP----------AVAPYGAFRTRDGQTVVLGTTNDREWQRLARDIIE
MMAR_0311|M.marinum_M VYPRT----------VAPNRRPYRTSDG-YLAALIYNDKHWAAFVDAVRP
MUL_4811|M.ulcerans_Agy99 VYPRT----------VAPNRRPYRTSDG-YLAALIYNDKHWAAFVDAVRP
Mb3300|M.bovis_AF2122/97 PEPAPKAKRRKGVGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIGR
Rv3272|M.tuberculosis_H37Rv PEPAPKAKRRKGVGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIGR
MAB_0824|M.abscessus_ATCC_1997 GNRHP----------SIAPYQTFETADR-PIAIAVGNDKQFRLLVQALEM
. . : * : .: . :
MAV_2651|M.avium_104 RRDLVDEPRFATNPDRVAHRDELESIITTVAARLSAEELEARLQSAGVAH
MSMEG_1992|M.smegmatis_MC2_155 RPEVAEDPRFASNTQRVANRADVNALISEVFSSHPTDELESRLTEARIAF
Mflv_2443|M.gilvum_PYR-GCK RPDLADDPRFATNPGRCANRDVLEEAIGAWCARHDLAEIQDKADRAGIGN
Mvan_4208|M.vanbaalenii_PYR-1 RPDLADDPRFATNSDRCAHRQILEEAIGSWCAQHDLAEIQKTADAAGIGN
TH_2496|M.thermoresistible__bu RPDLADDPAYATNSDRVRHRDVLNEAIAAWCARHDLAHIQKTADDAGIGN
MMAR_0311|M.marinum_M P---WASEQYATLEGRARQIDTVYALLAETFAARTTQEWLDLLEELEIPA
MUL_4811|M.ulcerans_Agy99 P---WASEQYATLEGRARQIDTVYALLAETFAARTTQEWLDLLEELEIPA
Mb3300|M.bovis_AF2122/97 P-DLVEDQRFAEQRSRSINYAELTAELELALASKTATEWVQLLQANGLMA
Rv3272|M.tuberculosis_H37Rv P-DLVEDQRFAEQRSRSINYAELTAELELALASKTATEWVQLLQANGLMA
MAB_0824|M.abscessus_ATCC_1997 P-RLARDDRFATNPLRVRHRGELVRVLEQRLREKNADDWYDTLTAVGVPA
. :* * : : : . :
MAV_2651|M.avium_104 ARMNGVDHLWLHPVLVGRDRWHEIQTPGGPAAALPPPAGLAGVDPVIG-D
MSMEG_1992|M.smegmatis_MC2_155 AGVNTVSEFLDHPVLAARDRWRSVETENGPVRALLPPLDLG-TEVRMD-P
Mflv_2443|M.gilvum_PYR-GCK SRYNLPSEVIAHPHLVARDRWRTVATPKGDIQALRPPPVISDFEQPMG-A
Mvan_4208|M.vanbaalenii_PYR-1 SRYNLPSEVVVHPHLAARDRWRTVATPKGDIQALRPPPVISDFEQPMG-A
TH_2496|M.thermoresistible__bu SRYNLPSEVVAHPHLSARDRWRPVDTPNGQITALRPPPVIEGFEQPMG-P
MMAR_0311|M.marinum_M SALSSPAELFDNQHLNAVGFFETIDTAHGPVRFPGVPTWFSRTPGRVSGP
MUL_4811|M.ulcerans_Agy99 SALSSPAELFDNQHLNAVGFFETIDTAHGPVRFPGVPTWFSRTPGRVLGP
Mb3300|M.bovis_AF2122/97 CLAHTWKQVVDTPLFAESDLTLEVGRGADTITVIRTPARYASFRAVVTDP
Rv3272|M.tuberculosis_H37Rv CLAHTWKQVVDTPLFAENDLTLEVGRGADTITVIRTPARYASFRAVVTDP
MAB_0824|M.abscessus_ATCC_1997 GPINDIAEAFRFAERLGLDVAVTVPGSPE--PQVANPISMSKTPVVYRNG
. . : *
MAV_2651|M.avium_104 VPALGEHSRKILH-ELGYSAQATDELIAAGVTTA----
MSMEG_1992|M.smegmatis_MC2_155 VPALGAHTAAILA-ELGHGDD-----------------
Mflv_2443|M.gilvum_PYR-GCK IPGLGEHTDAVLT-EFGVSAEELAQLRAEGAIGPAYRG
Mvan_4208|M.vanbaalenii_PYR-1 IPGLGEHTDAVLT-EIGVTPDELRQLRADGAIGPAYRG
TH_2496|M.thermoresistible__bu VPGLGQHTDAVLSGLLGMTDDEIAALREQGAIGPAYN-
MMAR_0311|M.marinum_M APQLGADTSAVLE-ELGINAADAQPAGPA---------
MUL_4811|M.ulcerans_Agy99 APQLGADTSAVLE-ELGINAADAQPAGPA---------
Mb3300|M.bovis_AF2122/97 PPTAGEHNAVFLARP-----------------------
Rv3272|M.tuberculosis_H37Rv PPTAGEHNAVFLARP-----------------------
MAB_0824|M.abscessus_ATCC_1997 PPRLGQSRA-----------------------------
* *