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aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_2143 | - | 100% (328) | POSSIBLE OXIDOREDUCTASE | |
M. thermoresistible (build 8) | TH_0078 | - | 3e-54 | 60.67% (178) | POSSIBLE OXIDOREDUCTASE |
M. thermoresistible (build 8) | TH_0077 | - | 3e-37 | 48.73% (158) | POSSIBLE OXIDOREDUCTASE |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0144 | - | 2e-88 | 52.63% (323) | putative oxidoreductase |
M. gilvum PYR-GCK | Mflv_2375 | - | 1e-105 | 56.97% (330) | NAD-dependent epimerase/dehydratase |
M. tuberculosis H37Rv | Rv0139 | - | 6e-89 | 52.94% (323) | oxidoreductase |
M. leprae Br4923 | MLBr_01964 | rmlB | 3e-12 | 26.16% (237) | dTDP-glucose 4,6-dehydratase |
M. abscessus ATCC 19977 | MAB_0718c | - | 7e-26 | 27.08% (325) | NAD-dependent epimerase/dehydratase |
M. marinum M | MMAR_0349 | - | 3e-91 | 52.78% (324) | oxidoreductase |
M. avium 104 | MAV_1849 | - | 1e-115 | 63.24% (321) | dihydroflavonol-4-reductase family protein |
M. smegmatis MC2 155 | MSMEG_6563 | - | 3e-99 | 54.08% (331) | dihydrokaempferol 4-reductase |
M. ulcerans Agy99 | MUL_4771 | - | 9e-91 | 52.47% (324) | oxidoreductase |
M. vanbaalenii PYR-1 | Mvan_4271 | - | 1e-108 | 58.48% (330) | NAD-dependent epimerase/dehydratase |
CLUSTAL 2.0.9 multiple sequence alignment Mb0144|M.bovis_AF2122/97 MNA-PKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDL Rv0139|M.tuberculosis_H37Rv MNA-PKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVRPAANTRSIDDL MMAR_0349|M.marinum_M MSVGPKLVIGANGFLGSHVTRMLIEDGA----QVRVMVRPTANTRSIDDL MUL_4771|M.ulcerans_Agy99 MSVGPKLVIGANGFLGSHVTRMLIEDGA----QVRVMVRPTANTRSIDDL Mflv_2375|M.gilvum_PYR-GCK -MAGTKLVIGASGFLGSHVTRQLVADGDA---DVRVLIRRTSSTRGIDGL Mvan_4271|M.vanbaalenii_PYR-1 -MAGTKLVIGASGFLGSHVTKQLIAAGED---DVRVLIRTTSSTRGIDGL MSMEG_6563|M.smegmatis_MC2_155 -MTATKLVIGASGFLGSHVTRRLVERGE----DVRILIRSTSSTRGIDDV MAV_1849|M.avium_104 --MAVKLVIGASGFLGSHVTRQLVERGE----RVRVLLRRTSSTVALDDL TH_2143|M.thermoresistible__bu -VAKKKLVIGASGFLGSHVTRQLVREGH----DVRVMVRTTSMTRGIDDL MAB_0718c|M.abscessus_ATCC_199 ---MKTAVTGAAGFIGTNLVNLLVDNGHEVIAIDRVVPASPETREAVTWV MLBr_01964|M.leprae_Br4923 -MTMRLLVTGGAGFIGANFVHNAVRDHPDDTVTVLDAMTYAGRHESLADV * *. **:*::... : . .: : Mb0144|M.bovis_AF2122/97 P--LTRFHGDVFDTATVAEAMAGCDDVYYCVVDTRAW--LRDPSPLFRTN Rv0139|M.tuberculosis_H37Rv P--LTRFHGDVFDTATVAEAMAGCDDVYYCVVDTRAW--LRDPSPLFRTN MMAR_0349|M.marinum_M P--VTRFHGDIFDTAVVREAMQGCDDVYYCVVDARAW--LRDPAPLFHTN MUL_4771|M.ulcerans_Agy99 P--VTRFHGDIFDTAVVREAMQGCDDVYYCVVDARAW--LRDPAPLFHTN Mflv_2375|M.gilvum_PYR-GCK P--VEVRYGDIFDADALRTAMSGCDVVYYCVVDARPW--LRDPRPMWRTN Mvan_4271|M.vanbaalenii_PYR-1 P--VQVHYGDIFDTGALRAAMAGCDVVYYCVVDARPW--LRDPAPMWRTN MSMEG_6563|M.smegmatis_MC2_155 IDRVDVRHGDIFDAASVRDAADGCDTVYYCVVDARAW--LRDATPLWRTN MAV_1849|M.avium_104 D--IERRYGDVFDDAVLRDALDGCDDVYYCVVDTRAW--LRDPAPLFRTN TH_2143|M.thermoresistible__bu D--VERCHGDVFDDAALRAAMTGVDDVYYCVVDARMW--LRDPAPLFRTN MAB_0718c|M.abscessus_ATCC_199 S-------GDVLDPDSMTKALDGVEVVYHLVAVITLK--HED-ELCWRIN MLBr_01964|M.leprae_Br4923 DHAVRLVQGNITDTKLVFRLVAESDVVVHFAAETHVDNALDDPEPFLRTN *:: * : : * : .. * : * Mb0144|M.bovis_AF2122/97 VAGLRNVLDVATD----ASLRRFVFTSSYATVGRRRGH--VATEEDRVDT Rv0139|M.tuberculosis_H37Rv VAGLRNVLDVATD----ASLRRFVFTSSYATVGRRRGH--VATEEDRVDT MMAR_0349|M.marinum_M VEGLRNVLDVAKN----AGLRRFVFTSSYATVDRRHGH--VATEEDRIGS MUL_4771|M.ulcerans_Agy99 VEGLRNVLDVAKN----AGLRRFVFTSSYATVDRRHGH--VATEEDRIGS Mflv_2375|M.gilvum_PYR-GCK VDGLRTVLDIAAD----AGLTRFVFTSSIGTIGLRAGG-PADERTEHNWL Mvan_4271|M.vanbaalenii_PYR-1 VDGLRNVLDVAVG----AGLHRFVFTSSIGTIGLAADG-LADEDTAHNWL MSMEG_6563|M.smegmatis_MC2_155 VDGLSGVLDVMTEPEIASGVRRFVFTSSIATIGLPESG-PATEEIENNWL MAV_1849|M.avium_104 VEGLRQVLDTAVG----ADLRRFVFTSTIGTIALSEDGLPVSEDEPFNWA TH_2143|M.thermoresistible__bu VEGLRHVLDAAVE----ADLNRFLFTSTTGTMAINPYR-PVTEDDPHNWT MAB_0718c|M.abscessus_ATCC_199 TEGARTVAQAALT----VGARRMVHCSSIDSYSNSVAT--IDEKSPRSAA MLBr_01964|M.leprae_Br4923 VIGTFTILEAVRHHS--VRLHHISTDEVYGDLELDEPT----RFTESTPY . * : : :: . Mb0144|M.bovis_AF2122/97 RKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGRTPHG-A Rv0139|M.tuberculosis_H37Rv RKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMCVSTTYGGGDWGRTPHG-A MMAR_0349|M.marinum_M RRVSSYVQSRVQAEDLVMDYVAQHGLPAVAMCVSTTYGSGDWGRTPHG-A MUL_4771|M.ulcerans_Agy99 RRVSSYVQSRVQAEDLVMDYVAQHGLPAVAMCVSTTYGSGDWGRTPHG-A Mflv_2375|M.gilvum_PYR-GCK DRGGEYIRSRVVAEEMVLRDSARNRLPGVAMCVANTYGPGDFQPTPHG-A Mvan_4271|M.vanbaalenii_PYR-1 DKGGAYIRSRVEAEQMVLRYSAEKGLPAVAMCVANTYGPGDFLPTPHG-G MSMEG_6563|M.smegmatis_MC2_155 DRGGEYVRSRVRAEQLVLRYHKDRGLPAVAMCVSNTYGPGDWQPTPHG-G MAV_1849|M.avium_104 DRGGGYIRSRVEAENLVLQYARERGLPAVAMCVSNTYGPGDFQPTPHG-S TH_2143|M.thermoresistible__bu -EGGAYIEARVAAEQLVLRYARERGLPAVALCISTTYGPGDWQPTPHG-R MAB_0718c|M.abscessus_ATCC_199 ADLPVYQRSKWGGEVAVRETIAS-GLDAVICNPTGVYGPVDLPNLSRINQ MLBr_01964|M.leprae_Br4923 NPSSPYSATKAAGDMLVRAWVRSYGVRATISNCSNNYGPYQHVEKFIP-R * :: .: * : .. : ** : Mb0144|M.bovis_AF2122/97 FIAGAVFGRLP--FTMRGIRLEAVGVDDAARALILAAERGHNGERYLISE Rv0139|M.tuberculosis_H37Rv FIAGAVFGRLP--FTMRGIRLEAVGVDDAARALILAAERGRNGERYLISE MMAR_0349|M.marinum_M FIAGAVFGKLP--FLMNGIKLEVVGVDDAARAMILAAERGRSGQRYLISE MUL_4771|M.ulcerans_Agy99 FIVGAVFGKLP--FLMNGIKLEVVGVDDAARAMILAAERGRSGQRYLISE Mflv_2375|M.gilvum_PYR-GCK MLAAAVRGKLP--FYIRGYEAEAVGIEDAARAMILAGERGRIGERYIVSD Mvan_4271|M.vanbaalenii_PYR-1 MLAAAVAGRLP--FYIDGYDAEVVGIEDAARAMILAAERGRTGERYIVSE MSMEG_6563|M.smegmatis_MC2_155 LVAAAVRGKMP--FYIDGAEAEAVGVADAAEALVLAGERGTPGERYIVSE MAV_1849|M.avium_104 LVAAAGKGKMP--VYVKDMSMEVVGIEDAARALILAAEKGRVGERYIVSE TH_2143|M.thermoresistible__bu LLAMVATGRFP--FYLG-WSAEVVGIEDAARAMLLAAEQGRVGERYIISD MAB_0718c|M.abscessus_ATCC_199 LLFDSARGRLP--GMVN-SQYDLVDARDVAAGLYLAGEKGRTGENYLLGG MLBr_01964|M.leprae_Br4923 QITNVLTGRRPKLYGTGVNVRDWIHVDDHNSAVWQILEKGQIGRTYLIGA : *: * : : * .: *:* *. *::. Mb0144|M.bovis_AF2122/97 RMMP-LQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTE Rv0139|M.tuberculosis_H37Rv RMMP-LQEVVRIAADEAGVPPPRWSISVPVLYALGALGSLRARLTGKDTE MMAR_0349|M.marinum_M RMIA-LKEVVRIAADEAGVAPPQRTISVPTLYALGALGSLRARLTGKDAE MUL_4771|M.ulcerans_Agy99 RMVA-LKEVVRIAADEAGVAPPQRTISVPTLYALGALGSLRARLTGKDAE Mflv_2375|M.gilvum_PYR-GCK RFIS-TREIHEIGCAAVGMRPPRFGVPIRAMAAAAHLGAAVARVRNTDTM Mvan_4271|M.vanbaalenii_PYR-1 RFMS-TREIHEIGCAAVGVAPPKFGVPIRVMSAAGYLSEGVARLRGKDTM MSMEG_6563|M.smegmatis_MC2_155 RMMS-AREIYEVACDAVGVEPPRRGVPIRVMAAAAGLSSAVARLRRRETR MAV_1849|M.avium_104 RYIS-ARELYTTAAEAGGARPPRIGIPLKVMYALGLCGDVAAKVLRRDML TH_2143|M.thermoresistible__bu RYLH-TREVHAIAAEAVGRRAPWFGLPLPVLSVAARGNDLAARLLRRDLM MAB_0718c|M.abscessus_ATCC_199 HMGS-LLQVCRLAARRAGKRGPRFAVPMGLLNAAIPVIEPIGKLLKN-DA MLBr_01964|M.leprae_Br4923 ENGHNNLTVLRTLLQMMGRDPNDFDHVTDRVGHDLRYAIDPTPLYNELCW . : * : : Mb0144|M.bovis_AF2122/97 LSLASVRMMRSEADVDHGKAVRELGWQPRPVEESIREAARFWAAMR--TV Rv0139|M.tuberculosis_H37Rv LSLASVRMMRSEADVDHGKAVRELGWQPRPVEESIREAARFWAAMR--TV MMAR_0349|M.marinum_M LSLESVRMMRAEAEVDHAKAVRELGWQPRPVEESIREAARFWASMRKNTQ MUL_4771|M.ulcerans_Agy99 LSLESVRMMRAEAEVDHAKAVRELGWQPRPVEESIREAARFWASMRKNTQ Mflv_2375|M.gilvum_PYR-GCK LTPLNIRLMHIMTPLDHSKAVRELGWHPRPLADSIVSAAHFFTDRRRSAA Mvan_4271|M.vanbaalenii_PYR-1 LTPLNIRLMHIMSPMDHSKAVRELDWHPQPTSEAIVAAAHFFRDRRQRAA MSMEG_6563|M.smegmatis_MC2_155 LSPLTVRLMHVMSPMDHGKAVRELGWKPAPAPESIAQAARFFASRRRT-- MAV_1849|M.avium_104 LSTLSVRLMHIMSPMDHSKAERELGWRPEPIHDAIRRAVAFYQTR----- TH_2143|M.thermoresistible__bu FAHVGLKMAELMSPLDHSKAERELGFKPEPVEDSIAKAARFFLEQHR--- MAB_0718c|M.abscessus_ATCC_199 LSRAAFNKLTVSPAVDITKARTELGYEPRSTETTVNEFVDFLLGSGRL-- MLBr_01964|M.leprae_Br4923 APKHANFDEGLRATIDWYRNN-ESWWRP------LKDAVEARYEERGR-- . . :* : * :.* : . Mb0144|M.bovis_AF2122/97 GKDPAAS- Rv0139|M.tuberculosis_H37Rv GKDPAAS- MMAR_0349|M.marinum_M GARTGQSE MUL_4771|M.ulcerans_Agy99 GARTGQPE Mflv_2375|M.gilvum_PYR-GCK PEGTR--- Mvan_4271|M.vanbaalenii_PYR-1 -QGAR--- MSMEG_6563|M.smegmatis_MC2_155 -------- MAV_1849|M.avium_104 -------- TH_2143|M.thermoresistible__bu -------- MAB_0718c|M.abscessus_ATCC_199 -------- MLBr_01964|M.leprae_Br4923 --------