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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_0078 | - | 100% (265) | POSSIBLE OXIDOREDUCTASE | |
| M. thermoresistible (build 8) | TH_2143 | - | 2e-54 | 60.67% (178) | POSSIBLE OXIDOREDUCTASE |
| M. thermoresistible (build 8) | TH_1114 | - | 2e-13 | 31.43% (175) | PROBABLE CHOLESTEROL DEHYDROGENASE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0144 | - | 5e-68 | 72.78% (180) | putative oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1108 | - | 1e-65 | 69.44% (180) | NAD-dependent epimerase/dehydratase |
| M. tuberculosis H37Rv | Rv0139 | - | 5e-68 | 72.78% (180) | oxidoreductase |
| M. leprae Br4923 | MLBr_01942 | - | 4e-10 | 27.98% (168) | putative cholesterol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2971c | - | 4e-10 | 33.59% (128) | putative oxidoreductase |
| M. marinum M | MMAR_0349 | - | 6e-67 | 70.45% (176) | oxidoreductase |
| M. avium 104 | MAV_5157 | - | 2e-70 | 72.78% (180) | 3-beta hydroxysteroid dehydrogenase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_6474 | - | 1e-68 | 75.71% (177) | nucleoside-diphosphate-sugar epimerase |
| M. ulcerans Agy99 | MUL_4771 | - | 4e-67 | 70.45% (176) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5705 | - | 6e-71 | 74.14% (174) | NAD-dependent epimerase/dehydratase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0349|M.marinum_M -----------MSVGPKLVIGANGFLGSHVTRMLIEDGA----QVRVMVR
MUL_4771|M.ulcerans_Agy99 -----------MSVGPKLVIGANGFLGSHVTRMLIEDGA----QVRVMVR
MAV_5157|M.avium_104 -----------MSGKPKLVIGANGFLGSHVTRQLVADGA----QVRAMVR
Mb0144|M.bovis_AF2122/97 -----------MN-APKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVR
Rv0139|M.tuberculosis_H37Rv -----------MN-APKLVIGANGFLGSHVTRQLVADCAPQKGEVRAMVR
Mflv_1108|M.gilvum_PYR-GCK ------------MSAPVLVIGANGYLGSHVTRKLVAA----GNDVRVMVR
Mvan_5705|M.vanbaalenii_PYR-1 ------------MTA--LVIGANGYLGSHVTRRLVAD----GQDVRVMVR
MSMEG_6474|M.smegmatis_MC2_155 ------------MSTS-LVIGANGFLGSHVLRQLVADNT-DGSEIRAMVR
TH_0078|M.thermoresistible__bu -----------VTARPKLVIGANGFLGSHVTRQLVADGH----QVRAMVR
MAB_2971c|M.abscessus_ATCC_199 --------------MRVLVTGGTGFVGGWTAKAMAEAGHKVRFLVRKEAR
MLBr_01942|M.leprae_Br4923 MLRGVGNASLTTELGRVLVTGGSGFVGANLVTALLERGY----QVRSFDR
** *..*::*. : :* *
MMAR_0349|M.marinum_M PTANTRSIDDLPVTRFHGDIFDTAVVREAMQGCDDVYYCVVDARAWLRD-
MUL_4771|M.ulcerans_Agy99 PTANTRSIDDLPVTRFHGDIFDTAVVREAMQGCDDVYYCVVDARAWLRD-
MAV_5157|M.avium_104 AGANTRGIDDLSLTRFHGDVFDTAVLSEAMDGVDDVYYCVVDTRAWVRD-
Mb0144|M.bovis_AF2122/97 PAANTRSIDDLPLTRFHGDVFDTATVAEAMAGCDDVYYCVVDTRAWLRD-
Rv0139|M.tuberculosis_H37Rv PAANTRSIDDLPLTRFHGDVFDTATVAEAMAGCDDVYYCVVDTRAWLRD-
Mflv_1108|M.gilvum_PYR-GCK DGANTVGIDDLAVTRYVGDIWNTDVLREAMTGCEVVYYCVVDTRGWLRD-
Mvan_5705|M.vanbaalenii_PYR-1 EGANTIGIDDLTVTRFVGDIWDDDVLREAMTGCDVVYYCVVDTRGWLRD-
MSMEG_6474|M.smegmatis_MC2_155 PGANTVGIDDLDVTRFTGDIFDTEVLRAAMTGCDVVYYCVVDTRGWLRH-
TH_0078|M.thermoresistible__bu PGANTVGIDDLALHRFHGDVFDTETLRAAMDGVDDVYYCVVDTRGWLRD-
MAB_2971c|M.abscessus_ATCC_199 LHTTVATLGVDVSDYAVGDITDRASVEAALDGCDAVVHSAAMVSTDPAE-
MLBr_01942|M.leprae_Br4923 APMPLP--QHPQLEVLQGDITDATVCTTAMDSIDTVFHTAAIIELMGGAS
**: : *: . : * : ..
MMAR_0349|M.marinum_M -----PAPLFHTNVEGLRNVLDVAKN----AGLRRFVFTSSYATVDRRHG
MUL_4771|M.ulcerans_Agy99 -----PAPLFHTNVEGLRNVLDVAKN----AGLRRFVFTSSYATVDRRHG
MAV_5157|M.avium_104 -----TSPLFRTNVEGLRNVLDVAVTQ---PELRKFIFTSTYATVGRRRG
Mb0144|M.bovis_AF2122/97 -----PSPLFRTNVAGLRNVLDVATD----ASLRRFVFTSSYATVGRRRG
Rv0139|M.tuberculosis_H37Rv -----PSPLFRTNVAGLRNVLDVATD----ASLRRFVFTSSYATVGRRRG
Mflv_1108|M.gilvum_PYR-GCK -----PAPLFRTNVEGTRNVLDVAVEPGIAATLRKFVFTSSCVTVGRTRG
Mvan_5705|M.vanbaalenii_PYR-1 -----PAPLFRTNVEGTRNVLNIAVEPAVAAGLRKFVFTSSYVTVGRRRG
MSMEG_6474|M.smegmatis_MC2_155 -----PAPLFRTNVEGTRHVLDVALEPGIG--LRKFVYTSSYVTVGRRRG
TH_0078|M.thermoresistible__bu -----PTPLFQTNVEGTRNVLNVALDVTEKAGLRRFVYTSSYVTVGRRRG
MAB_2971c|M.abscessus_ATCC_199 -----ADRMMAINLEGTRNVLGAAVDR----GLDPIVHVSSITALFRPGL
MLBr_01942|M.leprae_Br4923 VTDEYRQRSYTVNVGGTENLLRAGQKS----GVKRFVYTASNSVVMGGTP
*: * .::* . : ::..:: .:
MMAR_0349|M.marinum_M HVATEEDRIGS----RRVSSYVQSRVQAEDLVMDYVAQHGLPAVAMC---
MUL_4771|M.ulcerans_Agy99 HVATEEDRIGS----RRVSSYVQSRVQAEDLVMDYVAQHGLPAVAMC---
MAV_5157|M.avium_104 HVATEDDVIGT----RGLSDYVKSRVQAENLVMRYVAEAGLPAVAMC---
Mb0144|M.bovis_AF2122/97 HVATEEDRVDT----RKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMC---
Rv0139|M.tuberculosis_H37Rv HVATEEDRVDT----RKVTPYVRSRVAAEDLVLQYAHDAGLPAVAMC---
Mflv_1108|M.gilvum_PYR-GCK RVATEADVISDPADLKSLTPYVRSRVQAENLVMEYARERGLPAVAMC---
Mvan_5705|M.vanbaalenii_PYR-1 RVATEADVIAD----RGLTPYVRSRVQAENLVLEYARTRGLPAVAMC---
MSMEG_6474|M.smegmatis_MC2_155 CVATEDDVIDL----RGVTPYVRSRVQAEELVLRYATERGLPAVAMC---
TH_0078|M.thermoresistible__bu RRATEEDQIGN----RRVTPYVKSRVLAENLVLAYARERGLPAVAMC---
MAB_2971c|M.abscessus_ATCC_199 ETFAADLPAAG-----GSDGYGQSKARVELYVRALQ-DSGAPVTITY---
MLBr_01942|M.leprae_Br4923 ITGGDETMPYT---KRFNDLYTETKVVAEKFVLSQNGVPDGETMLTCSIR
* .::. .* * . .
MMAR_0349|M.marinum_M VSTTYGSGDWGRTPHGAFIAGAVFGKLPFLMNGIKLEVVGVDDAARAMIL
MUL_4771|M.ulcerans_Agy99 VSTTYGSGDWGRTPHGAFIVGAVFGKLPFLMNGIKLEVVGVDDAARAMIL
MAV_5157|M.avium_104 VSTTYGSGDWGRTPHGAFIAGAVFGKLPFTMEGIQLEVVGVTDAAKAMVL
Mb0144|M.bovis_AF2122/97 VSTTYGGGDWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALIL
Rv0139|M.tuberculosis_H37Rv VSTTYGGGDWGRTPHGAFIAGAVFGRLPFTMRGIRLEAVGVDDAARALIL
Mflv_1108|M.gilvum_PYR-GCK VSTTYGAGDWGRTPHGAIIAGAAFGKLPFVMGGIELEAVGIDDAAQAMLL
Mvan_5705|M.vanbaalenii_PYR-1 VSTTYGAGDWGRTPHGAIIAGAAFGKLPFVLGGIELEAVGVEDAAHALLL
MSMEG_6474|M.smegmatis_MC2_155 VSTTYGSGDWGRTPHGAVIAGAAFGKLPFVMSGIDLEAVGVDDAARALIL
TH_0078|M.thermoresistible__bu VSTTHSTG----PDH--------------------------DKEFPATVV
MAB_2971c|M.abscessus_ATCC_199 PGMVLGPPVGDQFGEAAEGVRWVLLTRSVPGRSAAWLVVDVRDLAALHTA
MLBr_01942|M.leprae_Br4923 PSGIWGRGDQTMFRKAFESVVSGHVKVLIGSKNAKLDNSYVHNLVHGLIL
. . . .
MMAR_0349|M.marinum_M AAE------RGRSGQRYLISERMIALKEVVRIAADEAGVAPPQRTISVPT
MUL_4771|M.ulcerans_Agy99 AAE------RGRSGQRYLISERMVALKEVVRIAADEAGVAPPQRTISVPT
MAV_5157|M.avium_104 AAD------RGRVGERYLISERMIALKEVVRIAADEAGVPPPRRSISVPT
Mb0144|M.bovis_AF2122/97 AAE------RGHNGERYLISERMMPLQEVVRIAADEAGVPPPRWSISVPV
Rv0139|M.tuberculosis_H37Rv AAE------RGRNGERYLISERMMPLQEVVRIAADEAGVPPPRWSISVPV
Mflv_1108|M.gilvum_PYR-GCK AAR------KGRAGERYLISEKMISNADVVRIAAEAAGVPAPTKKIPLVL
Mvan_5705|M.vanbaalenii_PYR-1 AAE------KGRVGERYLISEKMISNADVVRIAAEAAGVPAPSRTMPLPL
MSMEG_6474|M.smegmatis_MC2_155 AAE------SGRPGERYLISEKLISNAEVARIAAEAAGVAPPRRSIPLPV
TH_0078|M.thermoresistible__bu IAE------QESLGN----------------ITATTSPVDIP-RSRRTPA
MAB_2971c|M.abscessus_ATCC_199 LLE------PSRGPRRYTAGGHRLEVGELVDLLTEAAGSAVLAVPVPDSL
MLBr_01942|M.leprae_Br4923 AAEHLVPGGTAPGQAYFINDGEPINFFDFMGPIIKACGENWPRVRISGRL
.
MMAR_0349|M.marinum_M LYALGALGS-LRARLTGKDAELSLESVRMMRAEAEVDHAKAVRELGWQPR
MUL_4771|M.ulcerans_Agy99 LYALGALGS-LRARLTGKDAELSLESVRMMRAEAEVDHAKAVRELGWQPR
MAV_5157|M.avium_104 LYALGALGD-LRARLTGKDAELSLASVRMMRAEAPVDHSKAVRELGWQPR
Mb0144|M.bovis_AF2122/97 LYALGALGS-LRARLTGKDTELSLASVRMMRSEADVDHGKAVRELGWQPR
Rv0139|M.tuberculosis_H37Rv LYALGALGS-LRARLTGKDTELSLASVRMMRSEADVDHGKAVRELGWQPR
Mflv_1108|M.gilvum_PYR-GCK SYAMAALGS-AKSRLKGTDERMSLGSLRLMRAEAPVDCSKARRELGWQPR
Mvan_5705|M.vanbaalenii_PYR-1 SYAMAALGS-LKGRLKGTDERLSLDSLRLMRAEAPVDCGKAKRELGWQPR
MSMEG_6474|M.smegmatis_MC2_155 SYLLAAIGT-VKGKLRGTDERLSLRSLRLMRAECELDHSKAVRELGWQPR
TH_0078|M.thermoresistible__bu SRSAPAARA-SRX------------SRCACRPPTAAATGAAPRMARSSPR
MAB_2971c|M.abscessus_ATCC_199 LRAAGTVMD-QIGRYVPWETPMTEAGMQYYTQMPASDDTPSERELGITYR
MLBr_01942|M.leprae_Br4923 VRNVMAVWQRLHFGFGLPKPPMEPLAVERVYLDNYFSIEKAHKELGYRPL
: . : :
MMAR_0349|M.marinum_M -PVEESIREAARFWASMRKNTQGARTGQSE---------
MUL_4771|M.ulcerans_Agy99 -PVEESIREAARFWASMRKNTQGARTGQPE---------
MAV_5157|M.avium_104 -PVEESIREAARFWAAMRNAKGKSATPR-----------
Mb0144|M.bovis_AF2122/97 -PVEESIREAARFWAAMRTVGKDPAAS------------
Rv0139|M.tuberculosis_H37Rv -PVEESIREAARFWAAMRTVGKDPAAS------------
Mflv_1108|M.gilvum_PYR-GCK -PVEESIREAAKFWVGLKAAKRQRTA-------------
Mvan_5705|M.vanbaalenii_PYR-1 -PVEESIREAAKFWVGLRAAKRAGKAAG-----------
MSMEG_6474|M.smegmatis_MC2_155 -PVEESIAEAAKFWVGLRAAKQARRGG------------
TH_0078|M.thermoresistible__bu -RRSASCRS------------------------------
MAB_2971c|M.abscessus_ATCC_199 -DPRETLADTVVSLRAGRTTSKLWGLWPFSE--------
MLBr_01942|M.leprae_Br4923 FTTEQAMAECLPYYTELFEQIKVAAKPHLASIAATPRPE
: .