For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_2022 | - | - | 100% (274) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_4138 | - | 6e-21 | 28.52% (270) | PUTATIVE putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_3023 | - | 2e-19 | 39.61% (154) | PUTATIVE putative acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3593 | fadE32 | 3e-17 | 42.02% (119) | acyl-CoA dehydrogenase FADE32 |
| M. gilvum PYR-GCK | Mflv_2434 | - | 1e-101 | 69.57% (276) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv3573c | fadE34 | 4e-17 | 35.11% (225) | acyl-CoA dehydrogenase FADE34 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 2e-08 | 29.06% (117) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0594c | - | 3e-17 | 42.75% (131) | acyl-CoA dehydrogenase FadE |
| M. marinum M | MMAR_4749 | - | 2e-83 | 60.45% (268) | acyl-CoA dehydrogenase |
| M. avium 104 | MAV_0900 | - | 2e-89 | 62.17% (267) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4845 | - | 1e-116 | 76.69% (266) | putative acyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_2893 | fadE18 | 2e-17 | 40.62% (128) | acyl-CoA dehydrogenase FadE18 |
| M. vanbaalenii PYR-1 | Mvan_4218 | - | 1e-106 | 72.46% (276) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3593|M.bovis_AF2122/97 --------MTMEFALNEQQRDFAASIDAALGAADLPGVVRAWAAGDVAPG
MAB_0594c|M.abscessus_ATCC_199 ----------MKFDLDTQQRDFAASIDAALSVADVPAAARAWAAGNHGPG
TH_2022|M.thermoresistible__bu --------------VSVPDISGRSDLDAES--------------------
MSMEG_4845|M.smegmatis_MC2_155 -------------------------MDAES--------------------
Mflv_2434|M.gilvum_PYR-GCK ---------------MTVAIKDDAAMDEAS--------------------
Mvan_4218|M.vanbaalenii_PYR-1 ---------------------MAPGMDEAS--------------------
MMAR_4749|M.marinum_M ----------------------MDLTDPES--------------------
MAV_0900|M.avium_104 ---------------------MAPSADAES--------------------
MUL_2893|M.ulcerans_Agy99 ----------MDFRYSTEQDDFRESLRGFLRDQAPPARVRQVAAVGGHDK
Rv3573c|M.tuberculosis_H37Rv --MVATVTDEQSAARELVRGWARTAASGAAATAAVRDMEYGFEEGNADAW
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFP--
Mb3593|M.bovis_AF2122/97 RKVWQQLANLGVTALGVAEKFDG-LGASPVDLVVALERLGRWCVPGPVTE
MAB_0594c|M.abscessus_ATCC_199 LAVWSTLAELGVTALAVSEKYDG-IGAHPVDLVVALEGLGKWAVPGPVVE
TH_2022|M.thermoresistible__bu ---------LELLEDGLRKTML---SASGAELDAALGELG-WAQMLEDMP
MSMEG_4845|M.smegmatis_MC2_155 ---------LGLLEETLRKTML---SASGAKLDAALAELG-WAEMLSDMP
Mflv_2434|M.gilvum_PYR-GCK ---------LGMLEASLRKTMS---SASGPKLDAALTELG-WADMLTEAP
Mvan_4218|M.vanbaalenii_PYR-1 ---------LDMLEASLRKTML---SSSGPELDAALTEMG-WADMLSEVP
MMAR_4749|M.marinum_M ---------LRLLADSLKTAVTQNPSPSGAGLDAALQALG-WLDMLDEIP
MAV_0900|M.avium_104 ---------LRLLTDSLRTTMS---AASGAKLDAALTDVG-WRDMLDEMP
MUL_2893|M.ulcerans_Agy99 KLWHRLCAELELPALHAPPEYGG-AGGTLVETAIAFGELGRALTPVPFAA
Rv3573c|M.tuberculosis_H37Rv RPVFAGLAGLGLFGVAVPEDCGG-AGGSIEDLCAMVDEAARALVPGPVAT
MLBr_00737|M.leprae_Br4923 EEALAALNASGFNAIHVPEEYGG-QGADSVAACIVIEEVARVDASASLIP
. . . .
Mb3593|M.bovis_AF2122/97 SIAVA---------------PILLA-HDDRAERSH----G--LASGELIA
MAB_0594c|M.abscessus_ATCC_199 SVAVA---------------PVLLSSHEDGAEPST----R--LASGELIA
TH_2022|M.thermoresistible__bu DTAIP---------------LVFRLLGETGSHAS--------VLNDIVLE
MSMEG_4845|M.smegmatis_MC2_155 EVAMP---------------LVFRLLGETGSHAS--------VLNDVLLE
Mflv_2434|M.gilvum_PYR-GCK ELAIP---------------LYFRLLGETGSHAS--------ILVDVVLH
Mvan_4218|M.vanbaalenii_PYR-1 ELAVP---------------LVFRLLGETGSHAS--------VLVDVVLH
MMAR_4749|M.marinum_M GTAVP---------------LVFAMLGENGVHAP--------LVNDVVAR
MAV_0900|M.avium_104 DIAIP---------------LVFTLLGETGAHAP--------LLNDVLLC
MUL_2893|M.ulcerans_Agy99 TILAI---------------EAILRMGDSEQRKGL----LSGLLSGDRIG
Rv3573c|M.tuberculosis_H37Rv TAVAT---------------LVVSDPKLRSALASGERFAGVAIDGGVQVD
MLBr_00737|M.leprae_Br4923 AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMR
.
Mb3593|M.bovis_AF2122/97 TVAMPPRVPR-------------------------------AVDADTAGL
MAB_0594c|M.abscessus_ATCC_199 TVAAPPIAPR-------------------------------ALDADIAGL
TH_2022|M.thermoresistible__bu TIGALPGGTP-------------------------------PLPYAGGTW
MSMEG_4845|M.smegmatis_MC2_155 TIGGLPGGTP-------------------------------PMPYAGGGW
Mflv_2434|M.gilvum_PYR-GCK ATGNAIGDTVEL-----------------------------PLPYAGNAW
Mvan_4218|M.vanbaalenii_PYR-1 ATGNTIGDTVEL-----------------------------PLPYAGNGW
MMAR_4749|M.marinum_M AAGCPGGGTV-------------------------------PLPFAGGSW
MAV_0900|M.avium_104 AAGEAPGGTL-------------------------------ALPFTGGSW
MUL_2893|M.ulcerans_Agy99 ALAAAGPDLSVTSVRAGRRDGRPVLTGECAPVLHGHVADLFVVPAESDGA
Rv3573c|M.tuberculosis_H37Rv PKTSTASGTVGR-----------------------------VLGGAPGGV
MLBr_00737|M.leprae_Br4923 TRAKADGDDWILNG----------------------FKCWITNGGKSTWY
.
Mb3593|M.bovis_AF2122/97 VLLAGD------GSVTEGTPGDCHRSVDPSRRLYEVAASGQAWRAPKDV-
MAB_0594c|M.abscessus_ATCC_199 VLIADD------IGIREAQAGAQHESIDATRRVFDVQPKEAGISLDT---
TH_2022|M.thermoresistible__bu VVWERT------PTTEG------------SLGGLPLRRVPDGESMR----
MSMEG_4845|M.smegmatis_MC2_155 VVWERR------DSTDSA------DSANPTLGGLPLRKVPDGQLLR----
Mflv_2434|M.gilvum_PYR-GCK VVWDRG------GASEATGEDRGPESLDPTLGGLPLRREEEGYPIR----
Mvan_4218|M.vanbaalenii_PYR-1 VVWDRG------GASEATGDDRSPESLDPTLGGLPLRREEEGYPIR----
MMAR_4749|M.marinum_M VIWSRG------DQAGS-----------VLDGELPILRVEPADPLPP---
MAV_0900|M.avium_104 VLWERR------DSCDS-----------AIDELLPIHRVPQGDPLPA---
MUL_2893|M.ulcerans_Agy99 VILYVV------DAAAPGVAVVGLPSFDITRPVAKLRLVRAPAEALAASS
Rv3573c|M.tuberculosis_H37Rv VLLPADGNWLLVDTACDEVVVEPLRATDFSLPLARMVLTSAPVTVLEVS-
MLBr_00737|M.leprae_Br4923 TVMAVTDPDKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDK
.: :
Mb3593|M.bovis_AF2122/97 ------------------VARAYEFGALATAAQLVGAGQALLEAAVNYAK
MAB_0594c|M.abscessus_ATCC_199 -------------------SRAIDFGVLAISAQLIGAGQALLDRAVAYAK
TH_2022|M.thermoresistible__bu ----------------------LGEARKAVGWWLVGSARAMLTLARQHAL
MSMEG_4845|M.smegmatis_MC2_155 ----------------------ISEARRALGWWLVGSARAMLALARQHAM
Mflv_2434|M.gilvum_PYR-GCK ----------------------VAEARVAVGWWLVGSARAMLALARQHAL
Mvan_4218|M.vanbaalenii_PYR-1 ----------------------LAEARVAVGWWLVGSARAMLSLARQHAL
MMAR_4749|M.marinum_M --------------------AALAAGRSAVGWWLAGASRAMLELARRHAL
MAV_0900|M.avium_104 --------------------AALHAGWRALGWWLVGTSRAMLTLGRRHAV
MUL_2893|M.ulcerans_Agy99 ADE---------------VARLLDVARVLLAAEMLGGAEACLDLAIEYAC
Rv3573c|M.tuberculosis_H37Rv ------------------GERVEDLAATVLAAEAAGVARWTLDTAVAYAK
MLBr_00737|M.leprae_Br4923 CRIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTK
. * .. * . ::
Mb3593|M.bovis_AF2122/97 QRTQFGRAIGSYQAIKHKLADVHIAIELACPLVYGAAVSLE-------PR
MAB_0594c|M.abscessus_ATCC_199 QRSQFGRPIGSYQAVKHKLADVHIALELARPLVYGAALSLADQS-PTAAR
TH_2022|M.thermoresistible__bu DRVQFGKPIASFQAVRHRLAETLVAIEGAEAALRLPGTQSPD-------L
MSMEG_4845|M.smegmatis_MC2_155 DRVQFGAPIATFQAVRHRLAETLVAIEGAEATLSQPNADNVD-------L
Mflv_2434|M.gilvum_PYR-GCK DRVQFGKPIAGFQAVRHRLAETLVAIEGAEATLSLPSADNPD-------L
Mvan_4218|M.vanbaalenii_PYR-1 DRVQFGKPIASFQAVRHRLAETLVAIEGAEATLSLPGADNPD-------L
MMAR_4749|M.marinum_M DRNQFGHPIAAFQAVRHRLAEALVAIEGAEATLRAATDQPDE-------L
MAV_0900|M.avium_104 DRVQFGRHISSFQAIRHRLAEALVAVEGAEATLQAAAECDEDP-----GL
MUL_2893|M.ulcerans_Agy99 SRKQFDRPIGSFQAVKHRCADMMIEIDATRAAVMFAQLCAAGGD--ELHA
Rv3573c|M.tuberculosis_H37Rv VREQFGKPIGSFQAVKHLCAQMLCRAEQADVAAADAARAAADSDGTQLSI
MLBr_00737|M.leprae_Br4923 DRKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGE-PDLGF
* **. *. :*:::. *: : : .
Mb3593|M.bovis_AF2122/97 DVSAAKAAASEAALLAARSALQTHGAIGFTCEHDLSLWLLRVQALHSAWG
MAB_0594c|M.abscessus_ATCC_199 DASAAKVAAAKAAYLAARSALQTHGAIGFTAEYDLSLWILKVRALTSAWG
TH_2022|M.thermoresistible__bu TAMLAKAAAGKAALTAARNCQQVLGGIGFTAEHDLHRHVQRVLVLDGLLG
MSMEG_4845|M.smegmatis_MC2_155 TSLLAKAAAGKAALTAARHCQQVLGGIGFTAEHELHTHVERVLVLDGLLG
Mflv_2434|M.gilvum_PYR-GCK SSLLAKAAAGKAALTAAKNCQQVLGGIGFTEEHGLQHHVKRTLVLDGLLG
Mvan_4218|M.vanbaalenii_PYR-1 TALLAKAAAGKAALTAAMHCQQVLGGIGFTEEHHLHRHVKRALVLDGLLG
MMAR_4749|M.marinum_M ACLLAKAAAGQAALTTARHCQQVLAGMGFTAEHQLHHHVKRSLVLDGLLG
MAV_0900|M.avium_104 AALLAKAAAGQAALTTARHCQQVLGGIGFTAEHPLHHHIKRSLILDGLLG
MUL_2893|M.ulcerans_Agy99 TAPLAKAQAAGTYVLCAGSAIQVHGGIAFTWEHDLHLYFRRAKTTEALFG
Rv3573c|M.tuberculosis_H37Rv AAAVAASIGIDAAKANAKDCIQVLGGIGCTWEHDAHLYLRRAHGIGGFLG
MLBr_00737|M.leprae_Br4923 ISAASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEG
: . : . * .. . * :. . *
Mb3593|M.bovis_AF2122/97 TPQEHRRRVLEAL-------------------------------------
MAB_0594c|M.abscessus_ATCC_199 TSEWHRARVLEAL-------------------------------------
TH_2022|M.thermoresistible__bu SARELTLRVGAGLRARGSAPRLAYL-------------------------
MSMEG_4845|M.smegmatis_MC2_155 NARELTRKAGSGMRARGTAPRMAQV-------------------------
Mflv_2434|M.gilvum_PYR-GCK SSRELTRRAGAGLRARGSVPRLAQL-------------------------
Mvan_4218|M.vanbaalenii_PYR-1 SSRELTRRAGAGLRARGSAPRLAQL-------------------------
MMAR_4749|M.marinum_M SSRELTREAGAVLRTKGFAPRLAQL-------------------------
MAV_0900|M.avium_104 SARELTRQAGKTLVTTGSAPRLAQL-------------------------
MUL_2893|M.ulcerans_Agy99 SSAHHRSLLADRVGL-----------------------------------
Rv3573c|M.tuberculosis_H37Rv GSGRWLRRVTALTQAGVRRRLGVDLAEVAGLRPEIAAAVAEVAALPEEKR
MLBr_00737|M.leprae_Br4923 TNQIQRVVMSRALLR-----------------------------------
Mb3593|M.bovis_AF2122/97 --------------------------------------------------
MAB_0594c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4845|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2434|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4218|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4749|M.marinum_M --------------------------------------------------
MAV_0900|M.avium_104 --------------------------------------------------
MUL_2893|M.ulcerans_Agy99 --------------------------------------------------
Rv3573c|M.tuberculosis_H37Rv QVALADTGLLAPHWPAPYGRGASPAEQLLIDQELAAAKVERPDLVIGWWA
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
Mb3593|M.bovis_AF2122/97 --------------------------------------------------
MAB_0594c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4845|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2434|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4218|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4749|M.marinum_M --------------------------------------------------
MAV_0900|M.avium_104 --------------------------------------------------
MUL_2893|M.ulcerans_Agy99 --------------------------------------------------
Rv3573c|M.tuberculosis_H37Rv APTILEHGTPEQIERFVPATMRGEFLWCQLFSEPGAGSDLASLRTKAVRA
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
Mb3593|M.bovis_AF2122/97 --------------------------------------------------
MAB_0594c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4845|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2434|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4218|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4749|M.marinum_M --------------------------------------------------
MAV_0900|M.avium_104 --------------------------------------------------
MUL_2893|M.ulcerans_Agy99 --------------------------------------------------
Rv3573c|M.tuberculosis_H37Rv DGGWLLTGQKVWTSAAHKARWGVCLARTDPDAPKHKGITYFLVDMTTPGI
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
Mb3593|M.bovis_AF2122/97 --------------------------------------------------
MAB_0594c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4845|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2434|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4218|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4749|M.marinum_M --------------------------------------------------
MAV_0900|M.avium_104 --------------------------------------------------
MUL_2893|M.ulcerans_Agy99 --------------------------------------------------
Rv3573c|M.tuberculosis_H37Rv EIRPLREITGDSLFNEVFLDNVFVPDEMVVGAVNDGWRLARTTLANERVA
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
Mb3593|M.bovis_AF2122/97 --------------------------------------------------
MAB_0594c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4845|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2434|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4218|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4749|M.marinum_M --------------------------------------------------
MAV_0900|M.avium_104 --------------------------------------------------
MUL_2893|M.ulcerans_Agy99 --------------------------------------------------
Rv3573c|M.tuberculosis_H37Rv MATGTALGNPMEELLKVLGDMELDVAQQDRLGRLILLAQAGALLDRRIAE
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
Mb3593|M.bovis_AF2122/97 --------------------------------------------------
MAB_0594c|M.abscessus_ATCC_199 --------------------------------------------------
TH_2022|M.thermoresistible__bu --------------------------------------------------
MSMEG_4845|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_2434|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4218|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4749|M.marinum_M --------------------------------------------------
MAV_0900|M.avium_104 --------------------------------------------------
MUL_2893|M.ulcerans_Agy99 --------------------------------------------------
Rv3573c|M.tuberculosis_H37Rv LAVGGQDPGAQSSVRKLIGVRYRQALAEYLMEVSDGGGLVENRAVYDFLN
MLBr_00737|M.leprae_Br4923 --------------------------------------------------
Mb3593|M.bovis_AF2122/97 ---------------------------
MAB_0594c|M.abscessus_ATCC_199 ---------------------------
TH_2022|M.thermoresistible__bu ---------------------------
MSMEG_4845|M.smegmatis_MC2_155 ---------------------------
Mflv_2434|M.gilvum_PYR-GCK ---------------------------
Mvan_4218|M.vanbaalenii_PYR-1 ---------------------------
MMAR_4749|M.marinum_M ---------------------------
MAV_0900|M.avium_104 ---------------------------
MUL_2893|M.ulcerans_Agy99 ---------------------------
Rv3573c|M.tuberculosis_H37Rv TRCLTIAGGTEQILLTVAAERLLGLPR
MLBr_00737|M.leprae_Br4923 ---------------------------