For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4292 | - | - | 100% (306) | putative epoxide hydrolase |
| M. thermoresistible (build 8) | TH_0992 | ephA | 4e-20 | 28.75% (313) | PROBABLE EPOXIDE HYDROLASE EPHA (EPOXIDE HYDRATASE) |
| M. thermoresistible (build 8) | TH_2421 | - | 2e-16 | 26.67% (285) | PUTATIVE alpha/beta hydrolase fold |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2734 | - | 2e-13 | 35.71% (112) | hydrolase |
| M. gilvum PYR-GCK | Mflv_1415 | - | 3e-14 | 27.36% (307) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv3617 | ephA | 1e-19 | 30.28% (317) | epoxide hydrolase EphA |
| M. leprae Br4923 | MLBr_00862 | ephD | 2e-09 | 31.25% (112) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4522c | - | 3e-25 | 30.24% (291) | epoxide hydrolase EphF |
| M. marinum M | MMAR_0342 | ephF | 3e-21 | 27.74% (292) | epoxide hydrolase EphF |
| M. avium 104 | MAV_5163 | - | 1e-19 | 26.64% (304) | hydrolase, alpha/beta fold family protein |
| M. smegmatis MC2 155 | MSMEG_6720 | - | 1e-41 | 37.32% (284) | epoxide hydrolase |
| M. ulcerans Agy99 | MUL_4778 | ephF | 3e-21 | 26.97% (304) | epoxide hydrolase EphF |
| M. vanbaalenii PYR-1 | Mvan_3998 | - | 2e-18 | 25.88% (340) | alpha/beta hydrolase fold |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4292|M.thermoresistible__bu VVDTGAHAFDSATRDDDEFNRLFRHEFADVD-GVRMHYVTGG--SGDPLV
MSMEG_6720|M.smegmatis_MC2_155 ----------------MTSDVTLVHDSAYFD-DLKMHYVRAG--AGEPVV
Mflv_1415|M.gilvum_PYR-GCK -------------------MQS---RMVHTN-GITLRVFEAGERSAPVVV
Rv3617|M.tuberculosis_H37Rv -------------------MGAPTERLVDTN-GVRLRVVEAGEPGAPVVI
Mvan_3998|M.vanbaalenii_PYR-1 ----------------------MIHRNIDCN-GTRIHAVEQG--SGPLVI
MMAR_0342|M.marinum_M -------------MSTLPALDGVEHRFVDLDGGITIHVADAGPADGPAVM
MUL_4778|M.ulcerans_Agy99 -------------MSTLPALDGVEHRFVDLDGGITIHVADAGPADGPAVM
MAV_5163|M.avium_104 -------------MVTMPELDGVEHRYVDLGDDVTIHVADAGPASGPAVM
MAB_4522c|M.abscessus_ATCC_199 -----------MTQRSMPVLDGVEHQYVQAG-DVKIHVAVAGPQDGRAVV
MLBr_00862|M.leprae_Br4923 -------------MPATQSIHKVPHQFVESPDGVRLAIYQSGQPEGPAIV
Mb2734|M.bovis_AF2122/97 ---------MTERKRNLRPVRDVAPPTLQFRTVHGYRRAFRIAGSGPAIL
. ::
TH_4292|M.thermoresistible__bu LLHGWPQTWYAWRGIIPALAQK-YTVYALDLPGLGDSEGA--PPSYDKAT
MSMEG_6720|M.smegmatis_MC2_155 LLHGWPQTWYAWRKVIPLLAGE-FEVIVPDLRGCGDTSKP--SGGYDKKT
Mflv_1415|M.gilvum_PYR-GCK LCHGFPELAFTWRHQISALAAAGFHVLAPDQRGYGGSDKPGDAGVYNVAE
Rv3617|M.tuberculosis_H37Rv LAHGFPELAYSWRHQIPALADAGYHVLAPDQRGYGGSSRPEAIEAYDIHR
Mvan_3998|M.vanbaalenii_PYR-1 LLHGFPESWYSWRHQIPALANAGYRVVAIDQRGFGRSSKFRVNDAYRIDR
MMAR_0342|M.marinum_M LVHGFPENWWEWHELIGPLAADGYRVLCPDLRGAGWSSAP--RSRYTKKE
MUL_4778|M.ulcerans_Agy99 LVHGFPENWWEWHELIGPLAADGYRVLCPDLRGAGWSSAP--RSRYTKKE
MAV_5163|M.avium_104 LVHGFPQNWWEWRALIGPLAADGYRVLCPDLRGAGWSSAP--RSSYRKDE
MAB_4522c|M.abscessus_ATCC_199 LLHGWPENWWMWHKVIPALAAAGYRVHAMDLRGAGWSEVA--PAGYEKEQ
MLBr_00862|M.leprae_Br4923 LVHGFPDSHVLWDGVVPLLAKR-FRIVRYDNRGVGQSSVPKPVSAYTMTR
Mb2734|M.bovis_AF2122/97 LIHGIGDNSTTWNGVHAKLAQR-FTVIAPDLLGHGQSDKP--RADYSVAA
* ** : * ** : : * * * :. *
TH_4292|M.thermoresistible__bu LARFVHRLLADQLGLRSIRLVAHDLGAGVGFQYAAQY--PTEVSKYAHLD
MSMEG_6720|M.smegmatis_MC2_155 VAHDVRR-LVETLGHSAVHVVGHDIGAAVAYAYAAQW--PSEVQTMTFIE
Mflv_1415|M.gilvum_PYR-GCK LTADVVG-LLDDVGAERAALVGHDFGAVVAWGAPLLE--PDRFSAVAGLS
Rv3617|M.tuberculosis_H37Rv LTADLVG-LLDDVGAERAVWVGHDWGAVVVWNAPLLH--ADRVAAVAALS
Mvan_3998|M.vanbaalenii_PYR-1 VVADVEA-LIDAFGEEQAVVIGHDWGAPVAWTFAWLH--PQRCRGVVGVS
MMAR_0342|M.marinum_M MADDLAG-VLDRLGIASVRLVAHDWGGPVAFIMMLRY--PAKVTGFFGMN
MUL_4778|M.ulcerans_Agy99 MADDLAG-VLDRLGIASVRLVAHDWGGPVAFIMMLRY--PAKVTGFFGMN
MAV_5163|M.avium_104 MADDLAG-VLDRLGVRSVDLVAHDWGGPVAFIMMLRH--PEKVTGFFGVN
MAB_4522c|M.abscessus_ATCC_199 FASDVLA-AADALGLESFDLVGHDWGGWTAQLVALKA--QSRIRRLVVLN
MLBr_00862|M.leprae_Br4923 FADDFAAVIDELSPDRPVHVLAHDWGSVGVWEYLSRSGASDRVASFTSVS
Mb2734|M.bovis_AF2122/97 YANGMRD-LLSVLDIERVTIVGHSLGGGVAMQFAYQF--PQLVDRLILVS
. . . :.*. *. :.
TH_4292|M.thermoresistible__bu YPLP------------------GPALSAARYREFSWHMAFHHQPRVPEAV
MSMEG_6720|M.smegmatis_MC2_155 SSLSGF----------------GQEELMDVANGGSWHFGFNMAGDISEDL
Mflv_1415|M.gilvum_PYR-GCK LPPVPR-----------PQVPTTQAFRRVFGDRFMYILYFQEPGPADAEL
Rv3617|M.tuberculosis_H37Rv VPALPR-----------AQVPPTQAFRSRFGENFFYILYFQEPGIADAEL
Mvan_3998|M.vanbaalenii_PYR-1 VPFAGRGLIGLPGCPFGETRPRDYHIELAGPGRTFYQDYFSAQDGILYEI
MMAR_0342|M.marinum_M TAAPWF----------------PRDLGMVRDIWRFWYQIPIMLPVIGPRV
MUL_4778|M.ulcerans_Agy99 TAAPWF----------------PRDLGMVRDIWRFWYQIPILLPVIGPRV
MAV_5163|M.avium_104 TSAPFV----------------KRSLSTIRNVWRFWYQIPISLPVIGPRV
MAB_4522c|M.abscessus_ATCC_199 IPPVWQ----------------QPGR-VARYAHKLAYQLVVGAPVVGPLS
MLBr_00862|M.leprae_Br4923 GPSQDQLVDYILSGLRRPWRPRTFARAVSQLFRLTYMVLFSIPVLVPMVL
Mb2734|M.bovis_AF2122/97 AGGVTK----------------DVNIVFRLASLPMGSEAMALLRLPLVLP
TH_4292|M.thermoresistible__bu VANDVREYLALFYPYVAYGG------------------------------
MSMEG_6720|M.smegmatis_MC2_155 VRGRERLLIEYWMRRTTVG-------------------------------
Mflv_1415|M.gilvum_PYR-GCK ARDPATTFRRLFA-LTTGG----AEMVGDAGPQ----------------G
Rv3617|M.tuberculosis_H37Rv NGDPARTMRRMIGGLRPPGDQSAAMRMLAPGPD----------------G
Mvan_3998|M.vanbaalenii_PYR-1 EEDLRKWFLGLTYTVSGDAVAAAIADGHVPPADPVEALRYGPLCMVEGAR
MMAR_0342|M.marinum_M IADPKARYFRVLTSWVGGGF------------------------------
MUL_4778|M.ulcerans_Agy99 IADPKARYFRVLTSWVGGGF------------------------------
MAV_5163|M.avium_104 ISTPDSRFVRLLGSWVGGGY------------------------------
MAB_4522c|M.abscessus_ATCC_199 HLSPTLWWFIRRSG------------------------------------
MLBr_00862|M.leprae_Br4923 WIALSSATIRRTMVDNISTDQIHHSATLARDAAHSVKTYPANYFRAFSGR
Mb2734|M.bovis_AF2122/97 AVQIAGRIVGKAIGTTSLG-------------------------------
TH_4292|M.thermoresistible__bu ---TSFGGPGAQSPFTDEQVDEFARTYNRPDVLSGGFDLYR-TLDQDEHD
MSMEG_6720|M.smegmatis_MC2_155 --------VVDPTSVEPDALDEYARAMAQPGGLRGSFALYR-AIPQDRAD
Mflv_1415|M.gilvum_PYR-GCK FLDRIPEPGGLPDWISQADFDVYVDEFTRGG-FTGPLNWYR-CFDRNWEL
Rv3617|M.tuberculosis_H37Rv FIDRLPEPAGLPAWISQEELDHYIGEFTRTG-FTGGLNWYR-NFDRNWET
Mvan_3998|M.vanbaalenii_PYR-1 LDDAFVWPESMPQWFTEDDLDFYVNEFERSG-FAGGLAFYH-NVDAGWEV
MMAR_0342|M.marinum_M -------------TIADEDVRMYVERMRQPGHAVAGSRWYR-TFQSSEAL
MUL_4778|M.ulcerans_Agy99 -------------TIADEDVRMYVERMRQPGHAVAGSRWYR-TFQSSEAL
MAV_5163|M.avium_104 -------------TLPEEDVRLYLECMRQPGHAEAGSRWYR-SFQTREML
MAB_4522c|M.abscessus_ATCC_199 --------------MPKESVDFFRSCFRDRDRRVAGSKIYR-SMVGKEFA
MLBr_00862|M.leprae_Br4923 RRGKGVPVVNVPVQLIVNTMDRYVRPYGYDATARWVPRLWRRDIKAGHFS
Mb2734|M.bovis_AF2122/97 --------------HDLPNVLRILDDLPEPTASAAFGRTLR-AVVDWRGQ
. : .
TH_4292|M.thermoresistible__bu ---NVAAG--PITTPTLLMTA-----------------------------
MSMEG_6720|M.smegmatis_MC2_155 ---NRELGRTKLAMPVLAVEG-----------------------------
Mflv_1415|M.gilvum_PYR-GCK ---TAETPAPTIEVPALFVGG-----------------------------
Rv3617|M.tuberculosis_H37Rv ---TADLAGKTISVPSLFIAG-----------------------------
Mvan_3998|M.vanbaalenii_PYR-1 ---LDGVENQPLTPPAMFIGG-----------------------------
MMAR_0342|M.marinum_M PWMRGEYADARVDVPVRWLHG-----------------------------
MUL_4778|M.ulcerans_Agy99 PWMRGEYADARVDVPVRWLHG-----------------------------
MAV_5163|M.avium_104 SWMRGEYDGARVHVPVRWLSG-----------------------------
MAB_4522c|M.abscessus_ATCC_199 NLARGPYDDQKLTMPVRVLFG-----------------------------
MLBr_00862|M.leprae_Br4923 PMSHPQVMAAAVHDLADLVDGKQPSRALLRAQVGRSRDTFGDTLVSVTGA
Mb2734|M.bovis_AF2122/97 MVTMLDRCYLTEAIPVQIIWG-----------------------------
: .
TH_4292|M.thermoresistible__bu -------EGLLESTR-----LTVEPRMANITRAVEVPGAG----HWLVEE
MSMEG_6720|M.smegmatis_MC2_155 -------EHGQAGHS-----TETMKKVADHVTSAVIARAG----HYPAEE
Mflv_1415|M.gilvum_PYR-GCK -------TEDATLAY--TPRDRVREVVTGDYREVMIDGAG----HWLTEE
Rv3617|M.tuberculosis_H37Rv -------TADPVLTF--TRTDRAAEVISGPYREVLIDGAG----HWLQQE
Mvan_3998|M.vanbaalenii_PYR-1 -------EYDIATTWGAEAIARADEKMSDYRGSHLIAGAG----HWIQQE
MMAR_0342|M.marinum_M -------TEDPVLTP---QLLRGYEDHISDFEVEFVDGVG----HWIVEQ
MUL_4778|M.ulcerans_Agy99 -------TDDPVLTP---QLLRGYEDHISDFEVEFVDGVG----HWIVEQ
MAV_5163|M.avium_104 -------TEDPVLTP---DLLDGYAERIDDFQLELVDGVG----HWIVDQ
MAB_4522c|M.abscessus_ATCC_199 -------LDDVAVHP---SLLDGFKDHADDLNITEVPNCG----HFIVDE
MLBr_00862|M.leprae_Br4923 GSGIGRETALALARRGAEVVVSDIDEAAAKNTAAQIVASGGVAYAYALDV
Mb2734|M.bovis_AF2122/97 -------TKDVVLPVR---HAHMAHAAMPGSQLEIFEGSG----HFPFHD
. * : .
TH_4292|M.thermoresistible__bu NPAFVTNELLTFLAD-----------------------------------
MSMEG_6720|M.smegmatis_MC2_155 NPAELAAALRGFLLGG----------------------------------
Mflv_1415|M.gilvum_PYR-GCK RPDEVSRVLVDFLTTVR---------------------------------
Rv3617|M.tuberculosis_H37Rv RPGEVTAALLEFLTGLELR-------------------------------
Mvan_3998|M.vanbaalenii_PYR-1 RPAETNRLLLEFLGQLQ---------------------------------
MMAR_0342|M.marinum_M RPDLVLDRLRAFLRIET---------------------------------
MUL_4778|M.ulcerans_Agy99 RPDLVLDRLRAFLRIET---------------------------------
MAV_5163|M.avium_104 RPDLVLDRVRAFLRRET---------------------------------
MAB_4522c|M.abscessus_ATCC_199 QPELVVKWLSEVLAEPAP--------------------------------
MLBr_00862|M.leprae_Br4923 SDAAAVEAFAEQVSAKHGVPDIVVNNAGIGQAGRFLDTPPEEFDRVLAVN
Mb2734|M.bovis_AF2122/97 DPARFIDIVERFMDTTEPAEYDQAALRALLRRGGGEATVTGSADTRVAVL
. :
TH_4292|M.thermoresistible__bu --------------------------------------------------
MSMEG_6720|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1415|M.gilvum_PYR-GCK --------------------------------------------------
Rv3617|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_3998|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0342|M.marinum_M --------------------------------------------------
MUL_4778|M.ulcerans_Agy99 --------------------------------------------------
MAV_5163|M.avium_104 --------------------------------------------------
MAB_4522c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 LGGVVNCCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATY
Mb2734|M.bovis_AF2122/97 NAIGSNERSAT---------------------------------------
TH_4292|M.thermoresistible__bu --------------------------------------------------
MSMEG_6720|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1415|M.gilvum_PYR-GCK --------------------------------------------------
Rv3617|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_3998|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0342|M.marinum_M --------------------------------------------------
MUL_4778|M.ulcerans_Agy99 --------------------------------------------------
MAV_5163|M.avium_104 --------------------------------------------------
MAB_4522c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 MFSDCLRAELDAVGVGLTTICPGVIDTNIIQSTRIDTPTAKQERVRDRRG
Mb2734|M.bovis_AF2122/97 --------------------------------------------------
TH_4292|M.thermoresistible__bu --------------------------------------------------
MSMEG_6720|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_1415|M.gilvum_PYR-GCK --------------------------------------------------
Rv3617|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_3998|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0342|M.marinum_M --------------------------------------------------
MUL_4778|M.ulcerans_Agy99 --------------------------------------------------
MAV_5163|M.avium_104 --------------------------------------------------
MAB_4522c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 QLDMMFRLRRYGPDKVADTILSAIKKNKPIRPVAPEAYALYGISRVLPQV
Mb2734|M.bovis_AF2122/97 --------------------------------------------------
TH_4292|M.thermoresistible__bu ----------
MSMEG_6720|M.smegmatis_MC2_155 ----------
Mflv_1415|M.gilvum_PYR-GCK ----------
Rv3617|M.tuberculosis_H37Rv ----------
Mvan_3998|M.vanbaalenii_PYR-1 ----------
MMAR_0342|M.marinum_M ----------
MUL_4778|M.ulcerans_Agy99 ----------
MAV_5163|M.avium_104 ----------
MAB_4522c|M.abscessus_ATCC_199 ----------
MLBr_00862|M.leprae_Br4923 LRSTARIRVI
Mb2734|M.bovis_AF2122/97 ----------