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M. thermoresistible (build 8) TH_1484 (-)

annotation: methylesterase
coordinates: 2804440 - 2805495
length: 352

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1484--100% (352)methylesterase
M. thermoresistible (build 8)TH_0323-6e-1029.38% (160) POSSIBLE OXIDOREDUCTASE
M. thermoresistible (build 8)TH_3746-2e-0742.17% (83) PUTATIVE iron-sulfur cluster-binding protein, Rieske family

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3556-1e-0735.96% (89) oxidoreductase
M. gilvum PYR-GCKMflv_1843-1e-12161.58% (341) Rieske (2Fe-2S) domain-containing protein
M. tuberculosis H37RvRv3526-1e-0735.96% (89) oxidoreductase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0080c-2e-0829.23% (130) putative oxygenase
M. marinum MMMAR_3971-1e-0730.00% (180) oxidoreductase
M. avium 104MAV_3891-1e-13068.73% (339) methylesterase
M. smegmatis MC2 155MSMEG_2343-1e-12866.87% (329) methylesterase
M. ulcerans Agy99MUL_3829-3e-0729.44% (180) oxidoreductase
M. vanbaalenii PYR-1Mvan_1581-1e-12464.88% (336) Rieske (2Fe-2S) domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MAV_3891|M.avium_104                MNIRAQLRHLRPSVRAKDWPLQVIPRTPWADQRPTFREAQPAVIDAALQR
MSMEG_2343|M.smegmatis_MC2_155      MKIGDR--------WPKDWPLQLISSPRWSEQRPTYGEAKPAIIEAALRR
TH_1484|M.thermoresistible__bu      MSIAANLR----SRWAKTVPFQVLPPLRWAAQRPTFRAAEPAVIAGALTR
Mvan_1581|M.vanbaalenii_PYR-1       MSVLSGLR----ARAAKAWPFEFLPAASWSAQPPTYQDANPAVIDTALQR
Mflv_1843|M.gilvum_PYR-GCK          MSALGRLT----HSVKKAWPFEVLPRTAWARQSPTVGQASPQLIEAALAR
Mb3556|M.bovis_AF2122/97            ----------------------------MSTDTSG-----VGVREIDAGA
Rv3526|M.tuberculosis_H37Rv         ----------------------------MSTDTSG-----VGVREIDAGA
MAB_0080c|M.abscessus_ATCC_199      ----------------------------MTTAQSATEFDPATVRSIEADA
MMAR_3971|M.marinum_M               ----------------------MAPSTSNSASSSAEEHSEQEFGPSGIAL
MUL_3829|M.ulcerans_Agy99           ----------------------MAPSTSNSASNSAEELSEQEFGPSGIAL
                                                                 :   .        .       

MAV_3891|M.avium_104                CRRQPTGNWYAFAASTHVERGRPLGARVAGVDLVAWRDARGALCVGPRSC
MSMEG_2343|M.smegmatis_MC2_155      SQRRPTGNWYVLGANREIRADRPFGTTIGGIEVVAWRDRQGHLRVGPRSC
TH_1484|M.thermoresistible__bu      SQRRPGGNWFAFAAADRIG-DRPLGTRVGGVELVAWRGADGTLRVGPGAC
Mvan_1581|M.vanbaalenii_PYR-1       TLGRPGGNWFVIAASADIT-TKAFGTSVAGRELVAWRGSDGALLVAPRAC
Mflv_1843|M.gilvum_PYR-GCK          SQARPSGNWYVIAAGADVG-AKPVGATVAGAELVCWRGADGEVHAGPASC
Mb3556|M.bovis_AF2122/97            LPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKLVVFADSHGDLKVLDGYC
Rv3526|M.tuberculosis_H37Rv         LPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKLVVFADSHGDLKVLDGYC
MAB_0080c|M.abscessus_ATCC_199      APARFARGWYCLGLIKDFGDGKPHAVNAFGQKLVVFRPAGGKVSVLDAYC
MMAR_3971|M.marinum_M               SPYRFPTGWFIVAFSSELGAGEVKRVHYFGEELVLFRTASGRVHALDAYC
MUL_3829|M.ulcerans_Agy99           SPYRFPTGWFIVAFSSELGAGEVKRVHSFGEELVLFRTASGRVHALDAYC
                                       :   .*. ..        .   .   * .:* :    * : .    *

MAV_3891|M.avium_104                PHLGADLATG-TVCGGTLICRWHGLPLDG-------------RAREFGWA
MSMEG_2343|M.smegmatis_MC2_155      PHLGADLATG-VVDDGSLICRWHGLPLTG-------------KTCEFGWA
TH_1484|M.thermoresistible__bu      PHLGADLSTG-RVDHGTLVCPWHGLRLDG-------------GCREFGWS
Mvan_1581|M.vanbaalenii_PYR-1       PHLGADLATA-PVDCGTLVCPWHGLRLG--------------ERRHGAWK
Mflv_1843|M.gilvum_PYR-GCK          PHLGADLCTG-TVDRGQLVCPWHGLRLTG-------------RSRP-DWP
Mb3556|M.bovis_AF2122/97            RHMGGDLSEG-TVKGDEVACPFHDWRWGGDGRCKLVPYARR-TPRMARTR
Rv3526|M.tuberculosis_H37Rv         RHMGGDLSEG-TVKGDEVACPFHDWRWGGDGRCKLVPYARR-TPRMARTR
MAB_0080c|M.abscessus_ATCC_199      RHMGGDLSQG-EVKGDEIACPFHDWRWGGDGRCKKVPYSRR-TPKLARTA
MMAR_3971|M.marinum_M               QHLGANLGVGGTVEGEHIVCPWHGWQWRGDGTNALIPYSKIGCKNNVGIR
MUL_3829|M.ulcerans_Agy99           QHLGANLGVGGTVEGEHIVCPWHGWQWRGDGTNALIPYSKIGCKKNVRIR
                                     *:*.:*  .  *    : * :*.                          

MAV_3891|M.avium_104                PVPSHDDGTLAWVRLDAV--GGETPSPRPVIPPRPAGHTLASVAHLVG--
MSMEG_2343|M.smegmatis_MC2_155      PLPSHDDGVLAWVRLDEL--GGEDPLTVPVVPTRPAGETLHALTRLVG--
TH_1484|M.thermoresistible__bu      PYPSHDDGVLAWVRLDRV--GGENPTDRPVPAPRPAGVRLAAVTRLVG--
Mvan_1581|M.vanbaalenii_PYR-1       PYPAHDDGVLCWVRLDDLDTGASAPTEQPVIPLRPGEPALAAVTRMEG--
Mflv_1843|M.gilvum_PYR-GCK          SVPTFDDGVLVWARLDRI--GGEAPTEAPIVPVRPEAPTIAAVTTLHG--
Mb3556|M.bovis_AF2122/97            SWTTDVRSGLLFVWHDHE---GNPPDPAVRIPEIPEAASDEWTDWRWNRI
Rv3526|M.tuberculosis_H37Rv         SWTTDVRSGLLFVWHDHE---GNPPDPAVRIPEIPEAASDEWTDWRWNRI
MAB_0080c|M.abscessus_ATCC_199      TWITLEQDGMLFIWHDPQ---GNPPPEDVAIPRIEGATSPEWTDWHWYTT
MMAR_3971|M.marinum_M               SYPSIQWYGFILVWHERH---GRPP--YWEPPVLPELETNEYYPLHPHTR
MUL_3829|M.ulcerans_Agy99           SYPSIQWYGFILVWQERH---GRPP--YWQPPVLPELETNEYYSLHPHTR
                                    .  :     :     :     .  *      .                  

MAV_3891|M.avium_104                -----VCEPADIIANRLDPWHGAWFHPYSFTRLEVLAT------------
MSMEG_2343|M.smegmatis_MC2_155      -----VCEPSDIIANRLDPWHGNWFHPYSFTRLEVLST------------
TH_1484|M.thermoresistible__bu      -----RCEPHDIIANRLDPWHGAWFHPYSFTRLEVVSA------------
Mvan_1581|M.vanbaalenii_PYR-1       -----VCEPRDIVANRLDPWHGAWFHPYSFSRLRVLSA------------
Mflv_1843|M.gilvum_PYR-GCK          -----ACEAVDIIANRMDPWHGGWFHPYSFTKLDVLSA------------
Mb3556|M.bovis_AF2122/97            LIEGSNCR--DIIDNVTDMAHFFYIHFGLPTYFKNVFEGHIASQYLHNVG
Rv3526|M.tuberculosis_H37Rv         LIEGSNCR--DIIDNVTDMAHFFYIHFGLPTYFKNVFEGHIASQYLHNVG
MAB_0080c|M.abscessus_ATCC_199      VVN-TNCR--EIIDNVVDMAHFFYVHGAVPTYFKNIFEGHIATQYMN-TG
MMAR_3971|M.marinum_M               MLNRVKVHPQMIIENAADPYHVQYVHKAASPANTASFE--VSGYHLHATV
MUL_3829|M.ulcerans_Agy99           MLNRVKVHPQMIIENAADPYHVQYVHKAASPANTASFE--VSGYHLHATV
                                           .   *: *  *  *  :.*    .                   

MAV_3891|M.avium_104                --------PTE------EADRFLVAVTFRMGRLGVPVVAEFDCPEARTIV
MSMEG_2343|M.smegmatis_MC2_155      --------PTE------EDDRFLLSVTFRLGRLGVPVVAEFTCPSARTIV
TH_1484|M.thermoresistible__bu      --------PPPGIEVPPEEDRFLVAVTFRMGRLGVPVIAEFTAPGPRTIV
Mvan_1581|M.vanbaalenii_PYR-1       --------PPAEDGLAQDLDRFVVEVTFHIGRLGVPVIAEFTTPGPRTVV
Mflv_1843|M.gilvum_PYR-GCK          --------PGEDGDIPEELDRFLVAVTFRIGRLGVPVIAEFTSPEPRTLV
Mb3556|M.bovis_AF2122/97            RPDVDD-LGTSYGEAHLDSEASYFGPSFMINWLHNRYGNYKSESILINCH
Rv3526|M.tuberculosis_H37Rv         RPDVDD-LGTSYGEAHLDSEASYFGPSFMINWLHNRYGNYKSESILINCH
MAB_0080c|M.abscessus_ATCC_199      EPRADLPIPEGVQMTGQTSVASYYGPSFMIDDLTYHFVGYDSNSILINCH
MMAR_3971|M.marinum_M               NANFGGGRTKTWLTPNGPVDAKIIYDNYSLGLGIVRFPSELVATVQVTGQ
MUL_3829|M.ulcerans_Agy99           NANFGGGRTKTWLTPNGPVDAKIVYDNYSLGLGIVRFPSELVATVQVTGQ
                                                              .: :.            .   .  

MAV_3891|M.avium_104                MRIVDGEGTGSVVETHATPIGSGPD-GRPRTAVLEAVIAHSDRPGFARAL
MSMEG_2343|M.smegmatis_MC2_155      MRIVDGEGAGSIVETHATPLGPGTD-GRPRTAVVEAVVAQSDRAGFRHAR
TH_1484|M.thermoresistible__bu      MRIVDGEGAGSVVETHATPIGPGAD-GAPRTAVLEAVVAHSNRPNFVHAL
Mvan_1581|M.vanbaalenii_PYR-1       MHIVEGEGRGSVVETHATPLGPGVD-GRPRTAVIEAVIAHSDRPHFGAGL
Mflv_1843|M.gilvum_PYR-GCK          MRIVDGEGTGSVVETHATPQGYDRD-GRPRATVTEAVVAHSDRPGFARAM
Mb3556|M.bovis_AF2122/97            YPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVFTEGVSKGFLQDVEIWK
Rv3526|M.tuberculosis_H37Rv         YPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVFTEGVSKGFLQDVEIWK
MAB_0080c|M.abscessus_ATCC_199      YPIDANSFVLQYGIIVKKSAGLSDDDALAAAITLGDWIKAGFEQDVQIWK
MMAR_3971|M.marinum_M               TPVDEDYTDYFYTQASIREPGDAGDVPTGRAARFLALQQEVIKQDFFTWE
MUL_3829|M.ulcerans_Agy99           TPVDEDYTDYFYTQASIRELGDAGDVPTGRAARFLALQQEVIKQDFFTWE
                                      :  .              *   :     :              .    

MAV_3891|M.avium_104                WAAPLLTPVMRYAAGRLWRDDLAYAERRYEVRSQ---------------N
MSMEG_2343|M.smegmatis_MC2_155      RAAALITPLMRHAANRLWRDDLVYAERRYQIRHH---------------Q
TH_1484|M.thermoresistible__bu      RGAALIRPLMRRAATRLWRDDLAYAERLYRLRAD---------------R
Mvan_1581|M.vanbaalenii_PYR-1       VAAPLIRPLMRHAAGRLWRDDLAYAERLFEQRS-----------------
Mflv_1843|M.gilvum_PYR-GCK          RVAPMITPFMRHAANRLWRDDLVYAERLQTVREQKASGAADLLRPLPEPT
Mb3556|M.bovis_AF2122/97            HKTRIDNPLLVEEDG-AVYQLRRWYEQFYVDVADIKPEMVERFEIEVDTK
Rv3526|M.tuberculosis_H37Rv         HKTRIDNPLLVEEDG-AVYQLRRWYEQFYVDVADIKPEMVERFEIEVDTK
MAB_0080c|M.abscessus_ATCC_199      NKARIDNPLLCEEDG-PVYQLRRWYEQFYVDVADVTAEMTDRFEYEVDTT
MMAR_3971|M.marinum_M               NMKYLEKPNLAPEEARDYAALRRWAHRFYPAAQTSTADFGYTADGLPDPA
MUL_3829|M.ulcerans_Agy99           NMKYLEKPYLAPEEARDYAALRRWAHRFYPGAQTSPADFGYTADGLPDPA
                                        :  * :             : .:                       

MAV_3891|M.avium_104                H---------------------------
MSMEG_2343|M.smegmatis_MC2_155      RDHRRTTGQGP-----------------
TH_1484|M.thermoresistible__bu      RGGAAGSADGAGVVQ-------------
Mvan_1581|M.vanbaalenii_PYR-1       ----------------------------
Mflv_1843|M.gilvum_PYR-GCK          RGDRQPPAAAPGSAPTD-----------
Mb3556|M.bovis_AF2122/97            RANEFWNAEVEKNLKSREVSDDVPAEQH
Rv3526|M.tuberculosis_H37Rv         RANEFWNAEVEKNLKSREVSDDVPAEQH
MAB_0080c|M.abscessus_ATCC_199      RPGEAWKAQVEENLAA--MAGGAPS---
MMAR_3971|M.marinum_M               ASKA------------------------
MUL_3829|M.ulcerans_Agy99           ASKA------------------------