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MNIRAQLRHLRPSVRAKDWPLQVIPRTPWADQRPTFREAQPAVIDAALQRCRRQPTGNWYAFAASTHVER GRPLGARVAGVDLVAWRDARGALCVGPRSCPHLGADLATGTVCGGTLICRWHGLPLDGRAREFGWAPVPS HDDGTLAWVRLDAVGGETPSPRPVIPPRPAGHTLASVAHLVGVCEPADIIANRLDPWHGAWFHPYSFTRL EVLATPTEEADRFLVAVTFRMGRLGVPVVAEFDCPEARTIVMRIVDGEGTGSVVETHATPIGSGPDGRPR TAVLEAVIAHSDRPGFARALWAAPLLTPVMRYAAGRLWRDDLAYAERRYEVRSQNH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3891 | - | - | 100% (336) | methylesterase |
| M. avium 104 | MAV_1859 | - | 9e-10 | 41.03% (78) | iron-sulfur cluster-binding protein, Rieske family protein |
| M. avium 104 | MAV_1638 | - | 7e-08 | 30.06% (173) | Rieske (2Fe-2S) domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3556 | - | 6e-07 | 29.60% (125) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1843 | - | 1e-118 | 61.98% (334) | Rieske (2Fe-2S) domain-containing protein |
| M. tuberculosis H37Rv | Rv3526 | - | 6e-07 | 29.60% (125) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0080c | - | 2e-07 | 29.22% (154) | putative oxygenase |
| M. marinum M | MMAR_5015 | - | 1e-06 | 30.10% (103) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_2343 | - | 1e-139 | 70.89% (316) | methylesterase |
| M. thermoresistible (build 8) | TH_1484 | - | 1e-130 | 68.73% (339) | methylesterase |
| M. ulcerans Agy99 | MUL_4089 | - | 8e-07 | 30.10% (103) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_1581 | - | 1e-114 | 61.35% (326) | Rieske (2Fe-2S) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3891|M.avium_104 MNIRAQLRHLRPSVRAKDWPLQVIPRTPWADQRPTFREAQPAVIDAALQR
MSMEG_2343|M.smegmatis_MC2_155 MKIGDR--------WPKDWPLQLISSPRWSEQRPTYGEAKPAIIEAALRR
TH_1484|M.thermoresistible__bu MSIAANLR----SRWAKTVPFQVLPPLRWAAQRPTFRAAEPAVIAGALTR
Mvan_1581|M.vanbaalenii_PYR-1 MSVLSGLR----ARAAKAWPFEFLPAASWSAQPPTYQDANPAVIDTALQR
Mflv_1843|M.gilvum_PYR-GCK MSALGRLT----HSVKKAWPFEVLPRTAWARQSPTVGQASPQLIEAALAR
Mb3556|M.bovis_AF2122/97 ----------------------------MSTDTSG-----VGVREIDAGA
Rv3526|M.tuberculosis_H37Rv ----------------------------MSTDTSG-----VGVREIDAGA
MMAR_5015|M.marinum_M ----------------------------MSTDTTA-----VGVREIDAGI
MUL_4089|M.ulcerans_Agy99 ----------------------------MSTDTTA-----VGVREIDAGI
MAB_0080c|M.abscessus_ATCC_199 ----------------------------MTTAQSATEFDPATVRSIEADA
: . :
MAV_3891|M.avium_104 CRRQPTGNWYAFAASTHVERGRPLGARVAGVDLVAWRDARGALCVGPRSC
MSMEG_2343|M.smegmatis_MC2_155 SQRRPTGNWYVLGANREIRADRPFGTTIGGIEVVAWRDRQGHLRVGPRSC
TH_1484|M.thermoresistible__bu SQRRPGGNWFAFAAADRIG-DRPLGTRVGGVELVAWRGADGTLRVGPGAC
Mvan_1581|M.vanbaalenii_PYR-1 TLGRPGGNWFVIAASADIT-TKAFGTSVAGRELVAWRGSDGALLVAPRAC
Mflv_1843|M.gilvum_PYR-GCK SQARPSGNWYVIAAGADVG-AKPVGATVAGAELVCWRGADGEVHAGPASC
Mb3556|M.bovis_AF2122/97 LPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKLVVFADSHGDLKVLDGYC
Rv3526|M.tuberculosis_H37Rv LPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKLVVFADSHGDLKVLDGYC
MMAR_5015|M.marinum_M LPNRYARGWHCLGVAKDFMDGKPHGVEAFGTKLVVFTDSHGDLKILDSYC
MUL_4089|M.ulcerans_Agy99 LPNRYARGWHCLGVAKDFMDGKPHGVEAFGTKLVVFTDSHGDLKILDSYC
MAB_0080c|M.abscessus_ATCC_199 APARFARGWYCLGLIKDFGDGKPHAVNAFGQKLVVFRPAGGKVSVLDAYC
: .*. :. :. .. * .:* : * : *
MAV_3891|M.avium_104 PHLGADLATGTVCGGTLICRWHGLPLDG--RAREFGWAPVPSHDDGTLAW
MSMEG_2343|M.smegmatis_MC2_155 PHLGADLATGVVDDGSLICRWHGLPLTG--KTCEFGWAPLPSHDDGVLAW
TH_1484|M.thermoresistible__bu PHLGADLSTGRVDHGTLVCPWHGLRLDG--GCREFGWSPYPSHDDGVLAW
Mvan_1581|M.vanbaalenii_PYR-1 PHLGADLATAPVDCGTLVCPWHGLRLG---ERRHGAWKPYPAHDDGVLCW
Mflv_1843|M.gilvum_PYR-GCK PHLGADLCTGTVDRGQLVCPWHGLRLTG--RSRP-DWPSVPTFDDGVLVW
Mb3556|M.bovis_AF2122/97 RHMGGDLSEGTVKGDEVACPFHDWRWGGDGRCKLVPYARRTPRMARTRSW
Rv3526|M.tuberculosis_H37Rv RHMGGDLSEGTVKGDEVACPFHDWRWGGDGRCKLVPYARRTPRMARTRSW
MMAR_5015|M.marinum_M RHMGGDLSEGTIKGDEVACPFHDWRWGGDGRCKLVPYAKRTPRMARTRSW
MUL_4089|M.ulcerans_Agy99 RHMGGDLSEGTIKGDEVACPFHDWRWGGDGRCKLVPYAKRTPRMARTRSW
MAB_0080c|M.abscessus_ATCC_199 RHMGGDLSQGEVKGDEIACPFHDWRWGGDGRCKKVPYSRRTPKLARTATW
*:*.**. . : . : * :*. : .. . *
MAV_3891|M.avium_104 VRLDAV---------GGETPSPRPVIPPRPAGH-----TLASVAHLVGVC
MSMEG_2343|M.smegmatis_MC2_155 VRLDEL---------GGEDPLTVPVVPTRPAGE-----TLHALTRLVGVC
TH_1484|M.thermoresistible__bu VRLDRV---------GGENPTDRPVPAPRPAGV-----RLAAVTRLVGRC
Mvan_1581|M.vanbaalenii_PYR-1 VRLDDLDT-------GASAPTEQPVIPLRPGEP-----ALAAVTRMEGVC
Mflv_1843|M.gilvum_PYR-GCK ARLDRI---------GGEAPTEAPIVPVRPEAP-----TIAAVTTLHGAC
Mb3556|M.bovis_AF2122/97 TTDVRSGLLFVWHDHEGNPPDPAVRIPEIPEAASDEWTDWRWNRILIEGS
Rv3526|M.tuberculosis_H37Rv TTDVRSGLLFVWHDHEGNPPDPAVRIPEIPEAASDEWTDWRWNRILIEGS
MMAR_5015|M.marinum_M TTDVRGGLLFVWHDHEGNPPDPAVRIPEIPEAASDDWTQWRWNRILIEGS
MUL_4089|M.ulcerans_Agy99 TTDVRGGLFFVWHDHEGNPPDPAVRIPEIPEAASDDWTQWRWNRILIEGS
MAB_0080c|M.abscessus_ATCC_199 ITLEQDGMLFIWHDPQGNPPPEDVAIPRIEGATSPEWTDWHWYTTVVN-T
.. * . :
MAV_3891|M.avium_104 EPADIIANRLDPWHGAWFHPYSFTRLEVLATPTE------EADRFLVAVT
MSMEG_2343|M.smegmatis_MC2_155 EPSDIIANRLDPWHGNWFHPYSFTRLEVLSTPTE------EDDRFLLSVT
TH_1484|M.thermoresistible__bu EPHDIIANRLDPWHGAWFHPYSFTRLEVVSAPPPGIEVPPEEDRFLVAVT
Mvan_1581|M.vanbaalenii_PYR-1 EPRDIVANRLDPWHGAWFHPYSFSRLRVLSAPPAEDGLAQDLDRFVVEVT
Mflv_1843|M.gilvum_PYR-GCK EAVDIIANRMDPWHGGWFHPYSFTKLDVLSAPGEDGDIPEELDRFLVAVT
Mb3556|M.bovis_AF2122/97 NCRDIIDNVTDMAHFFYIHFGLPTYFKNVFEGHIASQYLHNVGRPDVDD-
Rv3526|M.tuberculosis_H37Rv NCRDIIDNVTDMAHFFYIHFGLPTYFKNVFEGHIASQYLHNVGRPDVDD-
MMAR_5015|M.marinum_M NCRDIIDNVTDMAHFFYIHFGLPTYFKNVFEGHIASQYLHNVGRPDVDD-
MUL_4089|M.ulcerans_Agy99 NCRDIIDNVTDMAHFFYIHFGLPTYFKNVFEGHIASQYLHNVGRPDVDD-
MAB_0080c|M.abscessus_ATCC_199 NCREIIDNVVDMAHFFYVHGAVPTYFKNIFEGHIATQYMN-TGEPRADLP
: :*: * * * :.* : : : ..
MAV_3891|M.avium_104 FRMGRLGVPVVAEFDCPEARTIVMRIVDGEG---TGSVVETHATPIGSGP
MSMEG_2343|M.smegmatis_MC2_155 FRLGRLGVPVVAEFTCPSARTIVMRIVDGEG---AGSIVETHATPLGPGT
TH_1484|M.thermoresistible__bu FRMGRLGVPVIAEFTAPGPRTIVMRIVDGEG---AGSVVETHATPIGPGA
Mvan_1581|M.vanbaalenii_PYR-1 FHIGRLGVPVIAEFTTPGPRTVVMHIVEGEG---RGSVVETHATPLGPGV
Mflv_1843|M.gilvum_PYR-GCK FRIGRLGVPVIAEFTSPEPRTLVMRIVDGEG---TGSVVETHATPQGYDR
Mb3556|M.bovis_AF2122/97 LGTSYGEAHLDSEASYFGPSFMINWLHNRYGNYKSESILINCHYPVTQNS
Rv3526|M.tuberculosis_H37Rv LGTSYGEAHLDSEASYFGPSFMINWLHNRYGNYKSESILINCHYPVTQNS
MMAR_5015|M.marinum_M LGTAYGEAHLDSEASYFGPSFMINWLHNSYGGYKSESILINCHYPVTQDS
MUL_4089|M.ulcerans_Agy99 LGTAYGEAHLDSEASYFGPSFMINWLHNSYGGYKSESILINCHYPVTQDS
MAB_0080c|M.abscessus_ATCC_199 IPEGVQMTGQTSVASYYGPSFMIDDLTYHFVGYDSNSILINCHYPIDANS
: . . : . :: : *:: . * .
MAV_3891|M.avium_104 DGRPRTAVLEAVIAHSDR------------------PGFARALWAAPLLT
MSMEG_2343|M.smegmatis_MC2_155 DGRPRTAVVEAVVAQSDR------------------AGFRHARRAAALIT
TH_1484|M.thermoresistible__bu DGAPRTAVLEAVVAHSNR------------------PNFVHALRGAALIR
Mvan_1581|M.vanbaalenii_PYR-1 DGRPRTAVIEAVIAHSDR------------------PHFGAGLVAAPLIR
Mflv_1843|M.gilvum_PYR-GCK DGRPRATVTEAVVAHSDR------------------PGFARAMRVAPMIT
Mb3556|M.bovis_AF2122/97 FVLQWGVIVEKPKGMSEEMTDKLSRVFTEGVSKGFLQDVEIWKHKTRIDN
Rv3526|M.tuberculosis_H37Rv FVLQWGVIVEKPKGMSEEMTDKLSRVFTEGVSKGFLQDVEIWKHKTRIDN
MMAR_5015|M.marinum_M FVLQWGVIVEKPKGMDEKMTDKLSRVFTEGVSKGFLQDVEIWKHKTRIDN
MUL_4089|M.ulcerans_Agy99 FVLQWGVIVEKPKGMDEKMTDKLSRVFTEGVSKGFLQDVEIWKHKTRIDN
MAB_0080c|M.abscessus_ATCC_199 FVLQYGIIVKKSAGLSDDDALAAAITLGDWIKAGFEQDVQIWKNKARIDN
: : . .: . : :
MAV_3891|M.avium_104 PVMRYAAGRLWRDDLAYAERRYEVRSQ---------------NH------
MSMEG_2343|M.smegmatis_MC2_155 PLMRHAANRLWRDDLVYAERRYQIRHH---------------QRDHRRTT
TH_1484|M.thermoresistible__bu PLMRRAATRLWRDDLAYAERLYRLRAD---------------RRGGAAGS
Mvan_1581|M.vanbaalenii_PYR-1 PLMRHAAGRLWRDDLAYAERLFEQRS------------------------
Mflv_1843|M.gilvum_PYR-GCK PFMRHAANRLWRDDLVYAERLQTVREQKASGAADLLRPLPEPTRGDRQPP
Mb3556|M.bovis_AF2122/97 PLLVEEDGAVYQLRRWYEQFYVDVADIKPEMVERFEIEVDTKRANEFWNA
Rv3526|M.tuberculosis_H37Rv PLLVEEDGAVYQLRRWYEQFYVDVADIKPEMVERFEIEVDTKRANEFWNA
MMAR_5015|M.marinum_M PLLVEEDGAVYQMRRWYEQFYVDAADVTPEMVERFEMEVDTTRANEFWRA
MUL_4089|M.ulcerans_Agy99 PLLVEEDGAVYQMRRWYEQFYVDAADVTPEMVERFEMEVDTTRANEFWRA
MAB_0080c|M.abscessus_ATCC_199 PLLCEEDGPVYQLRRWYEQFYVDVADVTAEMTDRFEYEVDTTRPGEAWKA
*.: ::: * :
MAV_3891|M.avium_104 ----------------------------
MSMEG_2343|M.smegmatis_MC2_155 GQGP------------------------
TH_1484|M.thermoresistible__bu ADGAGVVQ--------------------
Mvan_1581|M.vanbaalenii_PYR-1 ----------------------------
Mflv_1843|M.gilvum_PYR-GCK AAAPGSAPTD------------------
Mb3556|M.bovis_AF2122/97 EVEKNLKSR--------EVSDDVPAEQH
Rv3526|M.tuberculosis_H37Rv EVEKNLKSR--------EVSDDVPAEQH
MMAR_5015|M.marinum_M EVQQNLETKKLQEQQAESVPDDVPAEQH
MUL_4089|M.ulcerans_Agy99 EVQQNLETKKLQEQQAESVPDDVPAEQH
MAB_0080c|M.abscessus_ATCC_199 QVEENLAAM----------AGGAPS---