For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
KIGDRWPKDWPLQLISSPRWSEQRPTYGEAKPAIIEAALRRSQRRPTGNWYVLGANREIRADRPFGTTIG GIEVVAWRDRQGHLRVGPRSCPHLGADLATGVVDDGSLICRWHGLPLTGKTCEFGWAPLPSHDDGVLAWV RLDELGGEDPLTVPVVPTRPAGETLHALTRLVGVCEPSDIIANRLDPWHGNWFHPYSFTRLEVLSTPTEE DDRFLLSVTFRLGRLGVPVVAEFTCPSARTIVMRIVDGEGAGSIVETHATPLGPGTDGRPRTAVVEAVVA QSDRAGFRHARRAAALITPLMRHAANRLWRDDLVYAERRYQIRHHQRDHRRTTGQGP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2343 | - | - | 100% (338) | methylesterase |
| M. smegmatis MC2 155 | MSMEG_4372 | - | 7e-07 | 34.88% (86) | capreomycidine hydroxylase |
| M. smegmatis MC2 155 | MSMEG_2870 | - | 1e-05 | 30.23% (86) | oxygenase KshA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3556 | - | 5e-06 | 31.25% (64) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1843 | - | 1e-116 | 60.31% (325) | Rieske (2Fe-2S) domain-containing protein |
| M. tuberculosis H37Rv | Rv3526 | - | 5e-06 | 31.25% (64) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0726 | - | 6e-06 | 36.62% (71) | hypothetical protein MAB_0726 |
| M. marinum M | MMAR_3971 | - | 7e-08 | 29.07% (172) | oxidoreductase |
| M. avium 104 | MAV_3891 | - | 1e-139 | 70.89% (316) | methylesterase |
| M. thermoresistible (build 8) | TH_1484 | - | 1e-128 | 66.87% (329) | methylesterase |
| M. ulcerans Agy99 | MUL_3829 | - | 6e-08 | 27.91% (172) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_1581 | - | 1e-113 | 59.94% (327) | Rieske (2Fe-2S) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2343|M.smegmatis_MC2_155 MKIGDR--------WPKDWPLQLISSPRWSEQRPTYGEAKPAIIEAALRR
MAV_3891|M.avium_104 MNIRAQLRHLRPSVRAKDWPLQVIPRTPWADQRPTFREAQPAVIDAALQR
TH_1484|M.thermoresistible__bu MSIAANLR----SRWAKTVPFQVLPPLRWAAQRPTFRAAEPAVIAGALTR
Mvan_1581|M.vanbaalenii_PYR-1 MSVLSGLR----ARAAKAWPFEFLPAASWSAQPPTYQDANPAVIDTALQR
Mflv_1843|M.gilvum_PYR-GCK MSALGRLT----HSVKKAWPFEVLPRTAWARQSPTVGQASPQLIEAALAR
Mb3556|M.bovis_AF2122/97 -----------------------MSTDTSGVGVREIDAG----------A
Rv3526|M.tuberculosis_H37Rv -----------------------MSTDTSGVGVREIDAG----------A
MMAR_3971|M.marinum_M ----------------------MAPSTSNSASSSAEEHSEQEFGPSGIAL
MUL_3829|M.ulcerans_Agy99 ----------------------MAPSTSNSASNSAEELSEQEFGPSGIAL
MAB_0726|M.abscessus_ATCC_1997 -----------------------MPKPPLSMR------------------
. .
MSMEG_2343|M.smegmatis_MC2_155 SQRRPTGNWYVLGANREIRADRPFGTTIGGIEVVAWRDRQGHLRVGPRSC
MAV_3891|M.avium_104 CRRQPTGNWYAFAASTHVERGRPLGARVAGVDLVAWRDARGALCVGPRSC
TH_1484|M.thermoresistible__bu SQRRPGGNWFAFAAADRIG-DRPLGTRVGGVELVAWRGADGTLRVGPGAC
Mvan_1581|M.vanbaalenii_PYR-1 TLGRPGGNWFVIAASADIT-TKAFGTSVAGRELVAWRGSDGALLVAPRAC
Mflv_1843|M.gilvum_PYR-GCK SQARPSGNWYVIAAGADVG-AKPVGATVAGAELVCWRGADGEVHAGPASC
Mb3556|M.bovis_AF2122/97 LPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKLVVFADSHGDLKVLDGYC
Rv3526|M.tuberculosis_H37Rv LPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKLVVFADSHGDLKVLDGYC
MMAR_3971|M.marinum_M SPYRFPTGWFIVAFSSELGAGEVKRVHYFGEELVLFRTASGRVHALDAYC
MUL_3829|M.ulcerans_Agy99 SPYRFPTGWFIVAFSSELGAGEVKRVHSFGEELVLFRTASGRVHALDAYC
MAB_0726|M.abscessus_ATCC_1997 -----PTGWFQVAWSAQITVGAVHRMSYFGREMVAWRAQSGELAVMDAHC
.*. .. * .:* : * : . *
MSMEG_2343|M.smegmatis_MC2_155 PHLGADLATG-VVDDGSLICRWHGLPLTGKTCEFGWAPLPS---------
MAV_3891|M.avium_104 PHLGADLATG-TVCGGTLICRWHGLPLDGRAREFGWAPVPS---------
TH_1484|M.thermoresistible__bu PHLGADLSTG-RVDHGTLVCPWHGLRLDGGCREFGWSPYPS---------
Mvan_1581|M.vanbaalenii_PYR-1 PHLGADLATA-PVDCGTLVCPWHGLRLG-ERRHGAWKPYPA---------
Mflv_1843|M.gilvum_PYR-GCK PHLGADLCTG-TVDRGQLVCPWHGLRLTGRSRP-DWPSVPT---------
Mb3556|M.bovis_AF2122/97 RHMGGDLSEG-TVKGDEVACPFHDWRWGGDGRCKLVPYARR-TPRMARTR
Rv3526|M.tuberculosis_H37Rv RHMGGDLSEG-TVKGDEVACPFHDWRWGGDGRCKLVPYARR-TPRMARTR
MMAR_3971|M.marinum_M QHLGANLGVGGTVEGEHIVCPWHGWQWRGDGTNALIPYSKIGCKNNVGIR
MUL_3829|M.ulcerans_Agy99 QHLGANLGVGGTVEGEHIVCPWHGWQWRGDGTNALIPYSKIGCKKNVRIR
MAB_0726|M.abscessus_ATCC_1997 EHLGAHLGHGGHVEGDRIVCPFHGWEWNRDGRNVCIPYERR-PNPLRRIR
*:*..* . * : * :*.
MSMEG_2343|M.smegmatis_MC2_155 ------HDDGVLAWVRLDEL--GGEDPLTVPVVPTRPA------GETLHA
MAV_3891|M.avium_104 ------HDDGTLAWVRLDAV--GGETPSPRPVIPPRPA------GHTLAS
TH_1484|M.thermoresistible__bu ------HDDGVLAWVRLDRV--GGENPTDRPVPAPRPA------GVRLAA
Mvan_1581|M.vanbaalenii_PYR-1 ------HDDGVLCWVRLDDLDTGASAPTEQPVIPLRPG------EPALAA
Mflv_1843|M.gilvum_PYR-GCK ------FDDGVLVWARLDRI--GGEAPTEAPIVPVRPE------APTIAA
Mb3556|M.bovis_AF2122/97 SWTTDVRSGLLFVWHDHEGNPP--DPAVRIPEIPEAAS--DEWTDWRWNR
Rv3526|M.tuberculosis_H37Rv SWTTDVRSGLLFVWHDHEGNPP--DPAVRIPEIPEAAS--DEWTDWRWNR
MMAR_3971|M.marinum_M SYPSIQWYGFILVWHERHGRPPYWEPP-VLPELETN----EYYPLHPHTR
MUL_3829|M.ulcerans_Agy99 SYPSIQWYGFILVWQERHGRPPYWQPP-VLPELETN----EYYSLHPHTR
MAB_0726|M.abscessus_ATCC_1997 SYPVVERNEAVYIWHDTAGRPPYFDVPDVFTGFGDGGSARDYYPGYPHST
* . . .
MSMEG_2343|M.smegmatis_MC2_155 LTRLVGVCEPSDIIANRLDPWHGNWFHP-------------------YSF
MAV_3891|M.avium_104 VAHLVGVCEPADIIANRLDPWHGAWFHP-------------------YSF
TH_1484|M.thermoresistible__bu VTRLVGRCEPHDIIANRLDPWHGAWFHP-------------------YSF
Mvan_1581|M.vanbaalenii_PYR-1 VTRMEGVCEPRDIVANRLDPWHGAWFHP-------------------YSF
Mflv_1843|M.gilvum_PYR-GCK VTTLHGACEAVDIIANRMDPWHGGWFHP-------------------YSF
Mb3556|M.bovis_AF2122/97 ILIE--GSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFEGHIASQYLHNV
Rv3526|M.tuberculosis_H37Rv ILIE--GSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFEGHIASQYLHNV
MMAR_3971|M.marinum_M MLNR-VKVHPQMIIENAADPYHVQYVHK--AASPANTASFEVSGYHLHAT
MUL_3829|M.ulcerans_Agy99 MLNR-VKVHPQMIIENAADPYHVQYVHK--AASPANTASFEVSGYHLHAT
MAB_0726|M.abscessus_ATCC_1997 LYRERLQLHPQYVLENGVDFAHFKYVHK--TPFIPRFTRQEFG----TPI
: . :: * * * :.*
MSMEG_2343|M.smegmatis_MC2_155 TRLEVLSTPTE-------EDDRFLLSVTFRLGRLGVPVVAEFTCPSARTI
MAV_3891|M.avium_104 TRLEVLATPTE-------EADRFLVAVTFRMGRLGVPVVAEFDCPEARTI
TH_1484|M.thermoresistible__bu TRLEVVSAPPPGIEVPP-EEDRFLVAVTFRMGRLGVPVIAEFTAPGPRTI
Mvan_1581|M.vanbaalenii_PYR-1 SRLRVLSAPPAEDGLAQ-DLDRFVVEVTFHIGRLGVPVIAEFTTPGPRTV
Mflv_1843|M.gilvum_PYR-GCK TKLDVLSAPGEDGDIPE-ELDRFLVAVTFRIGRLGVPVIAEFTSPEPRTL
Mb3556|M.bovis_AF2122/97 GRPDVD-DLGTSYGEAHLDSEASYFGPSFMINWLHNRYGNYKSESILINC
Rv3526|M.tuberculosis_H37Rv GRPDVD-DLGTSYGEAHLDSEASYFGPSFMINWLHNRYGNYKSESILINC
MMAR_3971|M.marinum_M VNANFGGGRTKTWLTPNGPVDAKIIYDNYSLGLGIVRFPSELVATVQVTG
MUL_3829|M.ulcerans_Agy99 VNANFGGGRTKTWLTPNGPVDAKIVYDNYSLGLGIVRFPSELVATVQVTG
MAB_0726|M.abscessus_ATCC_1997 SYVDFTIAFDEIPGMSAEDIKSGVQAINGGLGVAVTKS-WGMVDNRTVSA
. . . :. .
MSMEG_2343|M.smegmatis_MC2_155 VMRIVDGEGAGSIVETHATPLGPGTDGRPR-TAVVEAVVAQSDRAGFRHA
MAV_3891|M.avium_104 VMRIVDGEGTGSVVETHATPIGSGPDGRPR-TAVLEAVIAHSDRPGFARA
TH_1484|M.thermoresistible__bu VMRIVDGEGAGSVVETHATPIGPGADGAPR-TAVLEAVVAHSNRPNFVHA
Mvan_1581|M.vanbaalenii_PYR-1 VMHIVEGEGRGSVVETHATPLGPGVDGRPR-TAVIEAVIAHSDRPHFGAG
Mflv_1843|M.gilvum_PYR-GCK VMRIVDGEGTGSVVETHATPQGYDRDGRPR-ATVTEAVVAHSDRPGFARA
Mb3556|M.bovis_AF2122/97 HYPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVFTEGVSKGFLQDVEIW
Rv3526|M.tuberculosis_H37Rv HYPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVFTEGVSKGFLQDVEIW
MMAR_3971|M.marinum_M QTPVDEDYTDYFYTQASIREPGDAGDVPTGRAARFLALQQEVIKQDFFTW
MUL_3829|M.ulcerans_Agy99 QTPVDEDYTDYFYTQASIRELGDAGDVPTGRAARFLALQQEVIKQDFFTW
MAB_0726|M.abscessus_ATCC_1997 VTPVDDETCDVRFTVFIGRQPGDDSAEPPQSAKTFAQAIIDQFLADIHIW
: : * : . .
MSMEG_2343|M.smegmatis_MC2_155 RRAAALITPLMRHAANRLWRDDLVYAERRYQIRHH---------------
MAV_3891|M.avium_104 LWAAPLLTPVMRYAAGRLWRDDLAYAERRYEVRSQ---------------
TH_1484|M.thermoresistible__bu LRGAALIRPLMRRAATRLWRDDLAYAERLYRLRAD---------------
Mvan_1581|M.vanbaalenii_PYR-1 LVAAPLIRPLMRHAAGRLWRDDLAYAERLFEQRS----------------
Mflv_1843|M.gilvum_PYR-GCK MRVAPMITPFMRHAANRLWRDDLVYAERLQTVREQKASGAADLLRPLPEP
Mb3556|M.bovis_AF2122/97 KHKTRIDNP-LLVEEDGAVYQLRRWYEQFYVDVADIKPEMVERFEIEVDT
Rv3526|M.tuberculosis_H37Rv KHKTRIDNP-LLVEEDGAVYQLRRWYEQFYVDVADIKPEMVERFEIEVDT
MMAR_3971|M.marinum_M ENMKYLEKPNLAPEEARDYAALRRWAHRFYPAAQTSTADFGYTADGLPDP
MUL_3829|M.ulcerans_Agy99 ENMKYLEKPYLAPEEARDYAALRRWAHRFYPGAQTSPADFGYTADGLPDP
MAB_0726|M.abscessus_ATCC_1997 SHQRYSDPPALVRAEYEGFIALRKWATQFYPEESTA--------------
* : : :
MSMEG_2343|M.smegmatis_MC2_155 QRDHRRTTGQGP-----------------
MAV_3891|M.avium_104 NH---------------------------
TH_1484|M.thermoresistible__bu RRGGAAGSADGAGVVQ-------------
Mvan_1581|M.vanbaalenii_PYR-1 -----------------------------
Mflv_1843|M.gilvum_PYR-GCK TRGDRQPPAAAPGSAPTD-----------
Mb3556|M.bovis_AF2122/97 KRANEFWNAEVEKNLKSREVSDDVPAEQH
Rv3526|M.tuberculosis_H37Rv KRANEFWNAEVEKNLKSREVSDDVPAEQH
MMAR_3971|M.marinum_M AASKA------------------------
MUL_3829|M.ulcerans_Agy99 AASKA------------------------
MAB_0726|M.abscessus_ATCC_1997 -----------------------------