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APSTSNSASNSAEELSEQEFGPSGIALSPYRFPTGWFIVAFSSELGAGEVKRVHSFGEELVLFRTASGRV HALDAYCQHLGANLGVGGTVEGEHIVCPWHGWQWRGDGTNALIPYSKIGCKKNVRIRSYPSIQWYGFILV WQERHGRPPYWQPPVLPELETNEYYSLHPHTRMLNRVKVHPQMIIENAADPYHVQYVHKAASPANTASFE VSGYHLHATVNANFGGGRTKTWLTPNGPVDAKIVYDNYSLGLGIVRFPSELVATVQVTGQTPVDEDYTDY FYTQASIRELGDAGDVPTGRAARFLALQQEVIKQDFFTWENMKYLEKPYLAPEEARDYAALRRWAHRFYP GAQTSPADFGYTADGLPDPAASKA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3829 | - | - | 100% (375) | oxidoreductase |
| M. ulcerans Agy99 | MUL_2161 | - | 1e-43 | 32.35% (340) | oxidoreductase |
| M. ulcerans Agy99 | MUL_4089 | - | 4e-24 | 25.07% (343) | oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3556 | - | 4e-25 | 25.60% (332) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4333 | - | 6e-51 | 34.25% (327) | Rieske (2Fe-2S) domain-containing protein |
| M. tuberculosis H37Rv | Rv3526 | - | 4e-25 | 25.60% (332) | oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0726 | - | 2e-49 | 33.33% (348) | hypothetical protein MAB_0726 |
| M. marinum M | MMAR_3971 | - | 0.0 | 96.53% (375) | oxidoreductase |
| M. avium 104 | MAV_1638 | - | 0.0 | 85.60% (375) | Rieske (2Fe-2S) domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_2244 | - | 6e-52 | 35.17% (327) | Rieske (2Fe-2S) domain-containing protein |
| M. thermoresistible (build 8) | TH_4194 | - | 2e-58 | 37.89% (322) | PUTATIVE putative Rieske [2Fe-2S] domain protein |
| M. vanbaalenii PYR-1 | Mvan_2012 | - | 1e-51 | 34.64% (332) | Rieske (2Fe-2S) domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3829|M.ulcerans_Agy99 MAPSTSNSASNSAEELSEQEFGPSGIALSPYRFPTGWFIVAFSSELGAGE
MMAR_3971|M.marinum_M MAPSTSNSASSSAEEHSEQEFGPSGIALSPYRFPTGWFIVAFSSELGAGE
MAV_1638|M.avium_104 MARTVSDSAPDSAEDPSEREFGQAGIALSTYRFPTGWFIVAFGSDLAPGQ
TH_4194|M.thermoresistible__bu ---------------------MIAGFPHT--RVPTGWYQIGWSFEFPVGE
Mflv_4333|M.gilvum_PYR-GCK -------------------------MKVPFTWKVTGWFMIGWSAEFEVGD
Mvan_2012|M.vanbaalenii_PYR-1 -------------------------MKVPFTWKVTGWFMIGWSAEYEVGE
MSMEG_2244|M.smegmatis_MC2_155 -------------------------MKVPFTWRVTGWFMIGWSAEYPVGE
MAB_0726|M.abscessus_ATCC_1997 ------------------------MPKPPLSMRPTGWFQVAWSAQITVGA
Mb3556|M.bovis_AF2122/97 -----------MSTDTSGVGVREIDAGALPTRYARGWHCLGVAKDYLEGK
Rv3526|M.tuberculosis_H37Rv -----------MSTDTSGVGVREIDAGALPTRYARGWHCLGVAKDYLEGK
**. :. . : *
MUL_3829|M.ulcerans_Agy99 VKRVHSFGEELVLFRTASGRVHALDAYCQHLGANLGVGGTVEGEHIVCPW
MMAR_3971|M.marinum_M VKRVHYFGEELVLFRTASGRVHALDAYCQHLGANLGVGGTVEGEHIVCPW
MAV_1638|M.avium_104 VKRAHYFGEELVLFRTASGRVHVMDAYCQHLGANLGVGGTVEGENIVCPW
TH_4194|M.thermoresistible__bu ARPLRYFGADLVAYRGHSGNVVVLNAHCLHMGAHLGHGGVVVDDEIECPF
Mflv_4333|M.gilvum_PYR-GCK VKALRYFGEDLAAYRDESGRLHVLEAHCKHLGAHIGHGGKVVDDCIECPF
Mvan_2012|M.vanbaalenii_PYR-1 VKALKYFGEDLAAYRDESGQLHVLEAHCKHLGAHIGHGGTVVGDCIECPF
MSMEG_2244|M.smegmatis_MC2_155 VKALKYFGEDLAAYRDESGHLHVLEAHCKHLGAHIGHGGKVVGECIECPF
MAB_0726|M.abscessus_ATCC_1997 VHRMSYFGREMVAWRAQSGELAVMDAHCEHLGAHLGHGGHVEGDRIVCPF
Mb3556|M.bovis_AF2122/97 PHGVEAFGTKLVVFADSHGDLKVLDGYCRHMGGDLSEG-TVKGDEVACPF
Rv3526|M.tuberculosis_H37Rv PHGVEAFGTKLVVFADSHGDLKVLDGYCRHMGGDLSEG-TVKGDEVACPF
: ** .:. : * : .::.:* *:*..:. * * .: : **:
MUL_3829|M.ulcerans_Agy99 HGWQWRGDGTNALIPYSKIGCKKNVRIRSYPSIQWYGFILVWQERHGRPP
MMAR_3971|M.marinum_M HGWQWRGDGTNALIPYSKIGCKNNVGIRSYPSIQWYGFILVWHERHGRPP
MAV_1638|M.avium_104 HGWQWRGDGSNALIPYSKIGCKNNVRIRTYPSMEWYGFVLAWHERHGRAP
TH_4194|M.thermoresistible__bu HGWRWDAEGRNTHIPDGSPPKRGQHTMRCWSVAENCGVVLMWYDADGGKP
Mflv_4333|M.gilvum_PYR-GCK HGWRWGPDGSNTYIPYQPDRPNRGLRLRSYPVEEQYGCIFMWYQPQGKEP
Mvan_2012|M.vanbaalenii_PYR-1 HGWRWGPEGDNTYIPYRPDRPNRGLRLRSYPVREQYGCIFMWYQPQGKEP
MSMEG_2244|M.smegmatis_MC2_155 HGWRWGPEGTNTYIPYQPDKPNRGLRLRSYPVQEQYGCIFMWYQPHGKEP
MAB_0726|M.abscessus_ATCC_1997 HGWEWNRDGRNVCIPYE-RRPNPLRRIRSYPVVERNEAVYIWHDTAGRPP
Mb3556|M.bovis_AF2122/97 HDWRWGGDGRCKLVPYARRTPR-MARTRSWTTDVRSGLLFVWHDHEGNPP
Rv3526|M.tuberculosis_H37Rv HDWRWGGDGRCKLVPYARRTPR-MARTRSWTTDVRSGLLFVWHDHEGNPP
*.*.* :* :* . * :. : * : * *
MUL_3829|M.ulcerans_Agy99 YWQPP-------VLPELETNEYYSLHPHTRMLNRVKVHPQMIIENAADPY
MMAR_3971|M.marinum_M YWEPP-------VLPELETNEYYPLHPHTRMLNRVKVHPQMIIENAADPY
MAV_1638|M.avium_104 YWQPP-------VLPELETGEYYPLHPHTQMVNRVKVHPQMIIENAADPY
TH_4194|M.thermoresistible__bu TWEVP-------QLIE-DPDRYYPIDRASRYWS-VRVHPQMVSENAIDSA
Mflv_4333|M.gilvum_PYR-GCK QWELPDIFHKFPQFETDANAYYRPYPEFSSRADAIPVHPQIVAENGPDSS
Mvan_2012|M.vanbaalenii_PYR-1 QWELPDIFHKFPQFETDANAYYRPYPEFSSRADAIPVHPQIVAENGPDSS
MSMEG_2244|M.smegmatis_MC2_155 QWELPDIFHKFPQFNTDPNAYYRPYPEFSSRADAIPVHPQIVAENGPDSS
MAB_0726|M.abscessus_ATCC_1997 YFDVPDVFTGFGDGGS-ARDYYPGYPHSTLYRERLQLHPQYVLENGVDFA
Mb3556|M.bovis_AF2122/97 DPAVR-----IPEIPEAASDEWTDWRWNRILIEGSNCR--DIIDNVTDMA
Rv3526|M.tuberculosis_H37Rv DPAVR-----IPEIPEAASDEWTDWRWNRILIEGSNCR--DIIDNVTDMA
: . : : :* *
MUL_3829|M.ulcerans_Agy99 HVQYVHKAASPANTASFEVSGYHLHATVNANFGGGRTKTWLTPNGPVDAK
MMAR_3971|M.marinum_M HVQYVHKAASPANTASFEVSGYHLHATVNANFGGGRTKTWLTPNGPVDAK
MAV_1638|M.avium_104 HVQYVHKAANPATTASFEVSGYHLHATVNAHFGGGRAQTWLTPNGPVDAK
TH_4194|M.thermoresistible__bu HFTYVHRAGSNPVILDIDDRGPILHVSQEMEFGSRKKSTWLTPDGPVKGS
Mflv_4333|M.gilvum_PYR-GCK HFRYVHGATVTPVCLHWEHVD--EEWRFLTGWPDARS----DDPDKMALR
Mvan_2012|M.vanbaalenii_PYR-1 HFRYVHKATVTPVCLHWEHVD--EEWRFLTGWPDARS----DDPDRMALK
MSMEG_2244|M.smegmatis_MC2_155 HFRYVHGATVTPVCLHWEHVD--EEWRFLTGWPDARS----DDPNKMALR
MAB_0726|M.abscessus_ATCC_1997 HFKYVHKTPFIPRFTRQEFGTPISYVDFTIAFDEIPG----MSAEDIKSG
Mb3556|M.bovis_AF2122/97 HFFYIHFG--LPTYFKNVFEG-HIASQYLHNVGRPDVDDLGTSYGEAHLD
Rv3526|M.tuberculosis_H37Rv HFFYIHFG--LPTYFKNVFEG-HIASQYLHNVGRPDVDDLGTSYGEAHLD
*. *:* .
MUL_3829|M.ulcerans_Agy99 IVYDNYS----LGLGIVRFPSELVATVQVTGQTPVDEDYTDYFYTQASIR
MMAR_3971|M.marinum_M IIYDNYS----LGLGIVRFPSELVATVQVTGQTPVDEDYTDYFYTQASIR
MAV_1638|M.avium_104 IIYDNYS----LGLGVVRFPSELVATVQVTGQTPVDEDYTDYFYTQASVR
TH_4194|M.thermoresistible__bu LEIDLFG----LGLSHTRFAGADEAYTLVG-VTPIDGETSAYRMTNWALR
Mflv_4333|M.gilvum_PYR-GCK IHSHFSG----LGFAMSAFE-GSSNHRLIFACTPVDDEVSDMFYSIWWPK
Mvan_2012|M.vanbaalenii_PYR-1 IHSHFSG----LGFAMSAFE-GSSNHRLIFACTPVDDEVSDMFYSIWWPK
MSMEG_2244|M.smegmatis_MC2_155 IHSHFSG----LGFAMSAFE-GSSNHRLIFACTPVDDEVSDMFYSIWWPK
MAB_0726|M.abscessus_ATCC_1997 VQAINGG----LGVAVTKSW-GMVDNRTVSAVTPVDDETCDVRFTVFIGR
Mb3556|M.bovis_AF2122/97 SEASYFGPSFMINWLHNRYGNYKSESILINCHYPVTQNSFVLQWGVIVEK
Rv3526|M.tuberculosis_H37Rv SEASYFGPSFMINWLHNRYGNYKSESILINCHYPVTQNSFVLQWGVIVEK
. :. : *: : :
MUL_3829|M.ulcerans_Agy99 ELGDAGDVPT-GRAARFLALQQEVIKQDFFTWENMKYLEKPYLAPEEARD
MMAR_3971|M.marinum_M EPGDAGDVPT-GRAARFLALQQEVIKQDFFTWENMKYLEKPNLAPEEARD
MAV_1638|M.avium_104 EPGDTGDVPT-GRAARFLALQKEVIKQDFFTWENMKYLEKPNLAPEEAHD
TH_4194|M.thermoresistible__bu N--TDGDEPD-ELARRRIEEQFRQAERDFVIWENMIYIDKPPLMRSETRA
Mflv_4333|M.gilvum_PYR-GCK LPGETSDIPPAEVIEKVERQFLKTVWEDCDIWRYQKYVENPPLAKIDAKP
Mvan_2012|M.vanbaalenii_PYR-1 LPGETSDVPPPEVIEKVERQFLKTVWEDCDIWRYQKYVENPPLAKIDAKP
MSMEG_2244|M.smegmatis_MC2_155 EPGGASDIPPEHVRAKVEKQFLKTVWEDCDIWRYQKYVEHPALAKIDAKP
MAB_0726|M.abscessus_ATCC_1997 QPGDDSAEPP-QSAKTFAQAIIDQFLADIHIWSHQRYSDPPALVRAEYEG
Mb3556|M.bovis_AF2122/97 PKGMSEEMTD-KLSRVFTEGVSKGFLQDVEIWKHKTRIDNPLLVEEDG-A
Rv3526|M.tuberculosis_H37Rv PKGMSEEMTD-KLSRVFTEGVSKGFLQDVEIWKHKTRIDNPLLVEEDG-A
. * * : * * :
MUL_3829|M.ulcerans_Agy99 YAALRRWAHRFYPGAQTSPADFGYTADGLPDPAASKA-------------
MMAR_3971|M.marinum_M YAALRRWAHRFYPAAQTSTADFGYTADGLPDPAASKA-------------
MAV_1638|M.avium_104 YAALRRWAHRFYPGPQPAPTDFGYTADGEPDPAAAKA-------------
TH_4194|M.thermoresistible__bu YRAFHTWAERFYTGSG--------ADARAADVRAGKR-------------
Mflv_4333|M.gilvum_PYR-GCK YMAMRKWAQRFYEVPP-VGDPVASR-------------------------
Mvan_2012|M.vanbaalenii_PYR-1 YMAMRKWAQQFYEVPAKVPAPATTA-------------------------
MSMEG_2244|M.smegmatis_MC2_155 YMAMRKWATQFYEVPP-VETALPRG-------------------------
MAB_0726|M.abscessus_ATCC_1997 FIALRKWATQFYPEES---TA-----------------------------
Mb3556|M.bovis_AF2122/97 VYQLRRWYEQFYVDVADIKPEMVERFEIEVDTKRANEFWNAEVEKNLKSR
Rv3526|M.tuberculosis_H37Rv VYQLRRWYEQFYVDVADIKPEMVERFEIEVDTKRANEFWNAEVEKNLKSR
:: * :**
MUL_3829|M.ulcerans_Agy99 -----------
MMAR_3971|M.marinum_M -----------
MAV_1638|M.avium_104 -----------
TH_4194|M.thermoresistible__bu -----------
Mflv_4333|M.gilvum_PYR-GCK -----------
Mvan_2012|M.vanbaalenii_PYR-1 -----------
MSMEG_2244|M.smegmatis_MC2_155 -----------
MAB_0726|M.abscessus_ATCC_1997 -----------
Mb3556|M.bovis_AF2122/97 EVSDDVPAEQH
Rv3526|M.tuberculosis_H37Rv EVSDDVPAEQH