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M. tuberculosis H37Rv Rv3526 (-)

annotation: POSSIBLE OXIDOREDUCTASE
coordinates: 3962439 - 3963599
length: 386

VSTDTSGVGVREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGTKLVVFADSHGDLKVLDGYCRHM
GGDLSEGTVKGDEVACPFHDWRWGGDGRCKLVPYARRTPRMARTRSWTTDVRSGLLFVWHDHEGNPPDPA
VRIPEIPEAASDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFEGHIASQYLHNVG
RPDVDDLGTSYGEAHLDSEASYFGPSFMINWLHNRYGNYKSESILINCHYPVTQNSFVLQWGVIVEKPKG
MSEEMTDKLSRVFTEGVSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYEQFYVDVADIKPEMVER
FEIEVDTKRANEFWNAEVEKNLKSREVSDDVPAEQH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3526--100% (386)POSSIBLE OXIDOREDUCTASE

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3556-0.0100.00% (386) oxidoreductase
M. gilvum PYR-GCKMflv_1533-0.079.79% (376) Rieske (2Fe-2S) domain-containing protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4173-0.074.94% (387) oxidoreductase
M. marinum MMMAR_5015-0.089.09% (394) oxidoreductase
M. avium 104MAV_0633-0.091.19% (386) Rieske (2Fe-2S) domain-containing protein
M. smegmatis MC2 155MSMEG_5925-0.082.21% (371) Rieske (2Fe-2S) domain-containing protein
M. thermoresistible (build 8)TH_0377-0.082.31% (373) POSSIBLE OXIDOREDUCTASE
M. ulcerans Agy99MUL_4089-0.088.83% (394) oxidoreductase
M. vanbaalenii PYR-1Mvan_5225-0.079.89% (378) Rieske (2Fe-2S) domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv3526|M.tuberculosis_H37Rv         MSTDTSGVG--VREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGT
Mb3556|M.bovis_AF2122/97            MSTDTSGVG--VREIDAGALPTRYARGWHCLGVAKDYLEGKPHGVEAFGT
MMAR_5015|M.marinum_M               MSTDTTAVG--VREIDAGILPNRYARGWHCLGVAKDFMDGKPHGVEAFGT
MUL_4089|M.ulcerans_Agy99           MSTDTTAVG--VREIDAGILPNRYARGWHCLGVAKDFMDGKPHGVEAFGT
MAV_0633|M.avium_104                MATDTKPVG--IREIDPGALPTRYARGWHCLGVAKDFQDGKPHSIEAFGT
MSMEG_5925|M.smegmatis_MC2_155      MATETVG----IREIDTGALPDRYARGWHCLGPVKNFSDGKPHSVNIFGT
TH_0377|M.thermoresistible__bu      VSTHTAGSSG-IREIDTGTLPDRYARGWHCLGPVENFLDGKPHGIRAFGT
Mflv_1533|M.gilvum_PYR-GCK          MSTDTAG----IREIDTGALPDRYARGWHCLGPVKNFTDGEPHGIEIFGT
Mvan_5225|M.vanbaalenii_PYR-1       MSTEASAGTAHIREIDTGALPDRYARGWHCLGPVKNFLDGKPHGIEIFGT
MAB_4173|M.abscessus_ATCC_1997      MSTDTAGIG--VREIDVGELPTRYARGWHCLGVAESFRDGEPHAIDAFGT
                                    ::*.:      :**** * ** ********** .:.: :*:**.:  ***

Rv3526|M.tuberculosis_H37Rv         KLVVFADSHGDLKVLDGYCRHMGGDLSEGTVKGDEVACPFHDWRWGGDGR
Mb3556|M.bovis_AF2122/97            KLVVFADSHGDLKVLDGYCRHMGGDLSEGTVKGDEVACPFHDWRWGGDGR
MMAR_5015|M.marinum_M               KLVVFTDSHGDLKILDSYCRHMGGDLSEGTIKGDEVACPFHDWRWGGDGR
MUL_4089|M.ulcerans_Agy99           KLVVFTDSHGDLKILDSYCRHMGGDLSEGTIKGDEVACPFHDWRWGGDGR
MAV_0633|M.avium_104                KLVVFADSHGDIHVLDGYCRHMGGDLSEGTIKGDEVACPFHDWRWGGDGR
MSMEG_5925|M.smegmatis_MC2_155      KLVVFADSKGELNVLDAYCRHMGGDLSKGTVKGDEVACPFHDWRWGGDGK
TH_0377|M.thermoresistible__bu      KLVVFADSSGELKILDAYCRHMGGDLSQGTIKGDEVACPFHDWRWGGDGK
Mflv_1533|M.gilvum_PYR-GCK          MLVVFADSQGELKVLDGYCRHMGGNLAQGTIKGDEVACPFHDWRWGGDGK
Mvan_5225|M.vanbaalenii_PYR-1       MLVVFADSQGELNVLDGYCRHMGGNLAQGEIKGDEVACPFHDWRWGGDGK
MAB_4173|M.abscessus_ATCC_1997      KLVVFADTQGDIKVLDGYCRHMGGDLSQGSIKGDNVACPFHDWRWGGDGK
                                     ****:*: *::::**.*******:*::* :***:**************:

Rv3526|M.tuberculosis_H37Rv         CKLVPYARRTPRMARTRSWTTDVRSGLLFVWHDHEGNPPDPAVRIPEIPE
Mb3556|M.bovis_AF2122/97            CKLVPYARRTPRMARTRSWTTDVRSGLLFVWHDHEGNPPDPAVRIPEIPE
MMAR_5015|M.marinum_M               CKLVPYAKRTPRMARTRSWTTDVRGGLLFVWHDHEGNPPDPAVRIPEIPE
MUL_4089|M.ulcerans_Agy99           CKLVPYAKRTPRMARTRSWTTDVRGGLFFVWHDHEGNPPDPAVRIPEIPE
MAV_0633|M.avium_104                CKLVPYAKRTPKTARTRSWTTDVRGGLLFVWHDHENNPPDPAVRIPEIPE
MSMEG_5925|M.smegmatis_MC2_155      CKLVPYAKRTPRLARTRSWHTDVRGGLLFVWHDHEGNPPQPEVRIPEIPE
TH_0377|M.thermoresistible__bu      CKLVPYAKRTPRLARTRAWHTDVRGGLLFVWHDHEGNPPQPEVRIPEIPE
Mflv_1533|M.gilvum_PYR-GCK          CKLVPYAKRTPRLARTRAWHTDVRGGLLFVWHDHEGNPPQPEVRIPEIPQ
Mvan_5225|M.vanbaalenii_PYR-1       CKLVPYAKRTPRLARTRAWHTDVRGGLLFVWHDHEGNPPQPEVRIPEIPE
MAB_4173|M.abscessus_ATCC_1997      CKLVPYAKRTPKLARTRSWITDVKSGLLFVWHDAEGNGPTDDVEIPEIPE
                                    *******:***: ****:* ***:.**:***** *.* *   *.*****:

Rv3526|M.tuberculosis_H37Rv         AASDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFE
Mb3556|M.bovis_AF2122/97            AASDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFE
MMAR_5015|M.marinum_M               AASDDWTQWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFE
MUL_4089|M.ulcerans_Agy99           AASDDWTQWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFE
MAV_0633|M.avium_104                AHSDEWTDWRWNRILIEGSNCRDIIDNVTDMAHFFYIHFGLPTYFKNVFE
MSMEG_5925|M.smegmatis_MC2_155      WHSGEWTDWKWNSMLIEGSNCREIIDNVTDMAHFFYIHFGLPTYFKNVFE
TH_0377|M.thermoresistible__bu      AHSDEWTDWRWNSILIEGANCREIIDNVTDMAHFFYIHFGMPTYFKNVFE
Mflv_1533|M.gilvum_PYR-GCK          WSSGEWTDWKWNTMLIEGSNCREIIDNVTDMAHFFYIHFGLPTYFKNVFE
Mvan_5225|M.vanbaalenii_PYR-1       WSSGEWTDWKWNTLLIEGSNCREIIDNVTDMAHFFYIHFGLPTYFKNVFE
MAB_4173|M.abscessus_ATCC_1997      YSDDGWTTWDWNTIVIEGSNCREIVDNVTDMAHFYYIHFGFPTYFKNVFE
                                      .. ** * ** ::***:***:*:*********:*****:*********

Rv3526|M.tuberculosis_H37Rv         GHIASQYLHNVGRPDVDDLGTS--YGEAHLDSEASYFGPSFMINWLHNRY
Mb3556|M.bovis_AF2122/97            GHIASQYLHNVGRPDVDDLGTS--YGEAHLDSEASYFGPSFMINWLHNRY
MMAR_5015|M.marinum_M               GHIASQYLHNVGRPDVDDLGTA--YGEAHLDSEASYFGPSFMINWLHNSY
MUL_4089|M.ulcerans_Agy99           GHIASQYLHNVGRPDVDDLGTA--YGEAHLDSEASYFGPSFMINWLHNSY
MAV_0633|M.avium_104                GHIASQYLHNVGRPDVNDLGTS--YGEAHLDSEASYFGPSFMINWLHNSY
MSMEG_5925|M.smegmatis_MC2_155      GHIASQYLHNVGRPDVNDLGTA--YGEAKLDSEASYFGPSFMINWLHNTY
TH_0377|M.thermoresistible__bu      GHIASQYLHNVGRPDVGDLGTA--YGESHLDSEASYFGPSFMINWLHNTY
Mflv_1533|M.gilvum_PYR-GCK          GHVASQYLHNVGRPDINDMGTA--YGDASLDSEASYFGPSFMINWLHNTY
Mvan_5225|M.vanbaalenii_PYR-1       GHIASQYLHNVGRPDVNDMGTA--YGEASLDSEASYFGPSFMINWLHNKY
MAB_4173|M.abscessus_ATCC_1997      GHIASQYLRTVGRPDVQLGGSSQYTGEQILDSEASYFGPSFMINWLHNNY
                                    **:*****:.*****:   *::   *:  ******************* *

Rv3526|M.tuberculosis_H37Rv         GNYKSESILINCHYPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVFTEG
Mb3556|M.bovis_AF2122/97            GNYKSESILINCHYPVTQNSFVLQWGVIVEKPKGMSEEMTDKLSRVFTEG
MMAR_5015|M.marinum_M               GGYKSESILINCHYPVTQDSFVLQWGVIVEKPKGMDEKMTDKLSRVFTEG
MUL_4089|M.ulcerans_Agy99           GGYKSESILINCHYPVTQDSFVLQWGVIVEKPKGMDEKMTDKLSRVFTEG
MAV_0633|M.avium_104                GDYKAESILINCHYPVTQNSFVLQWGVIVEKPKGMDEEMTDKLSRVFTEG
MSMEG_5925|M.smegmatis_MC2_155      GEFKAESILINCHYPVTQDSFVLQWGVIVEKPKGLDDATTEKLADAFTEG
TH_0377|M.thermoresistible__bu      GEFKAESILINCHYPVTQDSFVLQWGVIVEKPKGLDDETTQKLADAFTDG
Mflv_1533|M.gilvum_PYR-GCK          GDFKAESILINCHYPVSQDSFVLQWGVIVEKPQGLDDKTTEKLADAFTDG
Mvan_5225|M.vanbaalenii_PYR-1       GDFKAESILINCHYPVTQDSFVLQWGVIVEKPKGLDDGTTQKLADAFTDG
MAB_4173|M.abscessus_ATCC_1997      GGYKAESILINCHYPIDQNSFVLQYGVIVQKPAGMDEKMTGKLSRAMTKG
                                    * :*:**********: *:*****:****:** *:.:  * **: .:*.*

Rv3526|M.tuberculosis_H37Rv         VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYEQFYVDVADIKPE
Mb3556|M.bovis_AF2122/97            VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYEQFYVDVADIKPE
MMAR_5015|M.marinum_M               VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYEQFYVDAADVTPE
MUL_4089|M.ulcerans_Agy99           VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYEQFYVDAADVTPE
MAV_0633|M.avium_104                VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQLRRWYQQFYVDVADIEPE
MSMEG_5925|M.smegmatis_MC2_155      VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYQQFYVDVADITPD
TH_0377|M.thermoresistible__bu      VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYQQFYVDVADITPD
Mflv_1533|M.gilvum_PYR-GCK          VSKGFLQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYQQFYVDVADVTPE
Mvan_5225|M.vanbaalenii_PYR-1       VSKGFMQDVEIWKHKTRIDNPLLVEEDGAVYQMRRWYQQFYVDVADVTPE
MAB_4173|M.abscessus_ATCC_1997      VGQGFLQDVEIWKNKTRIDNPLLVEEDGAVYQMRRWYSQFYVDKADVTPE
                                    *.:**:*******:******************:****.***** **: *:

Rv3526|M.tuberculosis_H37Rv         MVERFEIEVDTKRANEFWNAEVEKNLKSR--------EVSDDVPAEQH--
Mb3556|M.bovis_AF2122/97            MVERFEIEVDTKRANEFWNAEVEKNLKSR--------EVSDDVPAEQH--
MMAR_5015|M.marinum_M               MVERFEMEVDTTRANEFWRAEVQQNLETKKLQEQQAESVPDDVPAEQH--
MUL_4089|M.ulcerans_Agy99           MVERFEMEVDTTRANEFWRAEVQQNLETKKLQEQQAESVPDDVPAEQH--
MAV_0633|M.avium_104                MVERFEIEVDTTRANEYWNAEVAQNLKAK---------ESEDVPAEQH--
MSMEG_5925|M.smegmatis_MC2_155      MTDRFEMEVDTTAAVEKWNIEVQENLKAQ----------AEAEKAEQSS-
TH_0377|M.thermoresistible__bu      MTDRFEIEVDTTAAVEYWTKQVEENLARQ----------AEEKKAEKAGD
Mflv_1533|M.gilvum_PYR-GCK          MTDRFEMEVDTTVANQKWNVEVEENLKAR----------EAEKTEQPAT-
Mvan_5225|M.vanbaalenii_PYR-1       MTDRFEMEVDTTAAVQKWNVEVEENLKAR----------ETETQST----
MAB_4173|M.abscessus_ATCC_1997      MTDRFELEIDTTKANEFWHGEVDENLQRQ---------ALEKEKAEQAAA
                                    *.:***:*:**. * : *  :* :**  :                     

Rv3526|M.tuberculosis_H37Rv         ---------------
Mb3556|M.bovis_AF2122/97            ---------------
MMAR_5015|M.marinum_M               ---------------
MUL_4089|M.ulcerans_Agy99           ---------------
MAV_0633|M.avium_104                ---------------
MSMEG_5925|M.smegmatis_MC2_155      ---------------
TH_0377|M.thermoresistible__bu      ARTENATRQGADQSS
Mflv_1533|M.gilvum_PYR-GCK          ---------------
Mvan_5225|M.vanbaalenii_PYR-1       ---------------
MAB_4173|M.abscessus_ATCC_1997      ESGSHAEATQS----