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M. thermoresistible (build 8) TH_1144 (-)

annotation: RNA polymerase sigma factor, sigma-70 family protein
coordinates: 2216707 - 2217627
length: 307

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1144--100% (307)RNA polymerase sigma factor, sigma-70 family protein
M. thermoresistible (build 8)TH_1142-e-11266.12% (304) RNA polymerase sigma factor, sigma-70 family protein
M. thermoresistible (build 8)TH_0604sigG1e-1628.84% (319) PROBABLE ALTERNATIVE RNA POLYMERASE SIGMA FACTOR SIGG (RNA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3361csigJ3e-4135.07% (288) RNA polymerase sigma factor SigJ
M. gilvum PYR-GCKMflv_1927-1e-10465.10% (298) ECF subfamily RNA polymerase sigma-24 factor
M. tuberculosis H37RvRv3328csigJ3e-4135.07% (288) RNA polymerase sigma factor SigJ
M. leprae Br4923MLBr_01076sigE2e-0724.83% (145) RNA polymerase sigma factor SigE
M. abscessus ATCC 19977MAB_4200-1e-10967.01% (294) putative sigma factor
M. marinum MMMAR_4487-1e-10362.59% (294) alternative RNA polymerase sigma factor
M. avium 104MAV_1129-1e-10664.43% (298) sigma factor
M. smegmatis MC2 155MSMEG_6817-1e-10063.73% (295) RNA polymerase sigma factor, sigma-70 family protein
M. ulcerans Agy99MUL_3630-2e-2930.00% (290) alternative RNA polymerase sigma factor SigJ- like
M. vanbaalenii PYR-1Mvan_5347-1e-11869.46% (298) ECF subfamily RNA polymerase sigma-24 factor

CLUSTAL 2.0.9 multiple sequence alignment


Mb3361c|M.bovis_AF2122/97           ------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLRW
Rv3328c|M.tuberculosis_H37Rv        ------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLRW
TH_1144|M.thermoresistible__bu      VTVGSAAGAADGEHAERFTLLRPLLFTIAYEILGSATEADDVLQDGYLRW
Mvan_5347|M.vanbaalenii_PYR-1       ------MTASTDEHGERFTVLRPLLFTIAYEILGSATESEDVLQDSYLRW
MAB_4200|M.abscessus_ATCC_1997      -------MINSDEHAERFTLLRPLLFTIVYEILGSATESDDVLQDSYLRW
MSMEG_6817|M.smegmatis_MC2_155      ------MTARLDDHTERFTMLRPLLFTIAYEILGSVTEADDVLQDSYLNW
MMAR_4487|M.marinum_M               ----MTPPSHSDEHAERFTLLRPLLFTIAYEILGSATESDDVLQESYLRW
MAV_1129|M.avium_104                ---MMTQAPTGSEHADRFTLLRPLLFTIAYEMLGSATEADDVLQDSYLRW
Mflv_1927|M.gilvum_PYR-GCK          -----MTAAPGDEHAERFTQLRPLLFTIAYEILGSATESDDVLQESYLRW
MUL_3630|M.ulcerans_Agy99           --------MTDPALLARFQAARPRLGALAYRMLGSLADAEDVVQEAWLRL
MLBr_01076|M.leprae_Br4923          -------------MGDGIGMEREGRWTGNTQCPLRVVPGD--------ES
                                                     :   *    :   .     . .:        . 

Mb3361c|M.bovis_AF2122/97           DSQD------TVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWLPEP
Rv3328c|M.tuberculosis_H37Rv        DSPD------TVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWLPEP
TH_1144|M.thermoresistible__bu      SQVDL-----GTVRDTKAFLAQLITREALKVLRTRSRRREDYVGPWLPEP
Mvan_5347|M.vanbaalenii_PYR-1       ADVDL-----ATVRDTKSYLAQLVTREALNALRARSRRREEYVGPWLPEP
MAB_4200|M.abscessus_ATCC_1997      AQVDL-----ATVRDTKSYLAQLVTRQALKALRTSVRRREDYIGPWLPEP
MSMEG_6817|M.smegmatis_MC2_155      AKVDL-----AAVRDTKSYLAQLVTRQALKAQRTSARRRESYVGPWLPEP
MMAR_4487|M.marinum_M               AAVDL-----SAVRDTKSYLAQLVTRQSLNALRAGARRREEYVGPWLPEP
MAV_1129|M.avium_104                STVDL-----ATVRDTKSYLAQLVTRQALNALRAGARRREEYVGPWLPEP
Mflv_1927|M.gilvum_PYR-GCK          AEVDL-----ATVTDTKAYLARLVTRQALNTLRAQSRRREDYVGPWLPEP
MUL_3630|M.ulcerans_Agy99           NATTDRPEGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELVGQLPDP
MLBr_01076|M.leprae_Br4923          PTLDG------RASPEDLIITNLLSPTIMSHPPPS--RDDDWVEPFDALQ
                                                       :: :::   :.       *         .  

Mb3361c|M.bovis_AF2122/97           VVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPFA
Rv3328c|M.tuberculosis_H37Rv        VVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPFA
TH_1144|M.thermoresistible__bu      --LLLEDHDPESDVVLAESVSMAMLVLLETLSPDERAVFVLREVFDFDYD
Mvan_5347|M.vanbaalenii_PYR-1       --LLLDERDASADIVLAESVSMAMLVLLETLTPDERAVFVLREVFGFDYD
MAB_4200|M.abscessus_ATCC_1997      --LLLDEHDGSADVLLAESVSMAMLILLETLTPDERAVFVLREVFGFGYD
MSMEG_6817|M.smegmatis_MC2_155      --LLLDDRDASADVVLAESVSMAMLVVLETLTPDERAVFVLHDVFGFDYA
MMAR_4487|M.marinum_M               --LLLDESDPSADLVLAESVSMAMLVLLETLTPDERAVFVLREVFGFDYD
MAV_1129|M.avium_104                --LLLDEQDPSTDVVLAESISMAMLVLLETLSPDERAVFVLREVFGFDYD
Mflv_1927|M.gilvum_PYR-GCK          --LLT-EADPSADVVLAESVSMAMLVVLETLSPDERAVFVLREVFGFGHD
MUL_3630|M.ulcerans_Agy99           IVDGVAAFDPEHHAMLADAVGLALFVVLDTLAPAERLAFVLHDVFAVPFD
MLBr_01076|M.leprae_Br4923          -----------GTAVFDATGDKATMPSWEELVR-QHAARVYWLAYRLSGN
                                                  :       * :   : *   :: . *    : .   

Mb3361c|M.bovis_AF2122/97           EVAEVLGTSEAAARQLASRARKAVTAQPALIS----GDPDPAHNEVVGRL
Rv3328c|M.tuberculosis_H37Rv        EVAEVLGTSEAAARQLASRARKAVTAQPALIS----GDPDPAHNEVVGRL
TH_1144|M.thermoresistible__bu      EIAGAVGKSVPAVRQVAHRSREHVRARRKRFD----PVPAAQTTELAEEF
Mvan_5347|M.vanbaalenii_PYR-1       EIAGAVGRSTQAVRQIAHRAKEHVHARRKRFG----PVDSRRTTQITEQF
MAB_4200|M.abscessus_ATCC_1997      EIAGAVSKSATAVRQIAHRAREHVHARRKRFD----PLDAKESTRIAEQF
MSMEG_6817|M.smegmatis_MC2_155      EISEAVGKSTAAVRQIAHRAREHVHARRKRFD----PVDSDQAAEITQQF
MMAR_4487|M.marinum_M               EIADAVGKPAPTVRQVAHRARAHIQARRKKYG----DVDPQRNAQLTAQF
MAV_1129|M.avium_104                EIAEAVGKPAPTVRQVARRAREHVRARRKRHPGAGQAIDPKRNAELTAQF
Mflv_1927|M.gilvum_PYR-GCK          EIAATLGKSTAAVRQIAHRAREHVQSRRKRFE----PVDPKTSGEITMTF
MUL_3630|M.ulcerans_Agy99           QIAPILERTPEATRKLASRARRRIERAEPFPD-----RDLCAQREVVDAF
MLBr_01076|M.leprae_Br4923          QHDAEDLTQETFIRVFRSVQNYQPGTFEGWLH------------RITTNL
                                    :            * .    .                       .:.  :

Mb3361c|M.bovis_AF2122/97           MAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILGL
Rv3328c|M.tuberculosis_H37Rv        MAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILGL
TH_1144|M.thermoresistible__bu      IHAATTGDLDRLLSLLAPGATFTTDHGGKAPAVARPVEGAKKVANLVMGF
Mvan_5347|M.vanbaalenii_PYR-1       LTAAATGDMEELVSMLAPGATWTADHGGKATAVRRPVVGARKVAAIMARV
MAB_4200|M.abscessus_ATCC_1997      LLATETGDVEGLMALLAPDATWIADGNGRAGAARRPLTGAGKLARIFAGP
MSMEG_6817|M.smegmatis_MC2_155      LTAASTGDMAGLVALLAPDVVTITDGGGLPGAARRPLVGAERVAGAIVRG
MMAR_4487|M.marinum_M               LQTAASGDVEALMAMLAPDATWLADSGGKVSAARKPVVGAERVARAITGL
MAV_1129|M.avium_104                LATAASGDVEALMAMLAPDATWTADSGGVVSAARRPVVGAEKVARAITGL
Mflv_1927|M.gilvum_PYR-GCK          FAAAATGDLDALMAMLAPDVVWTADSDGKVSAARRPVEGADKVARLILGF
MUL_3630|M.ulcerans_Agy99           FAAGRSGNFERLVSVLHPDVVLRGDFG--PNTPRFRAQGAATVAKLARSY
MLBr_01076|M.leprae_Br4923          FLDMVRRRARIRMDALPDDYDRVPADEPNPEQIYHDSRLGPDLQAALDSL
                                    :           :  *  .                    .  :       

Mb3361c|M.bovis_AF2122/97           VQRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITVRDGK
Rv3328c|M.tuberculosis_H37Rv        VQRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITVRDGK
TH_1144|M.thermoresistible__bu      FRNRHRVPDLRLEATNCNHAPAVLVYTG-------DHLEAVVLLEIVDGA
Mvan_5347|M.vanbaalenii_PYR-1       FQAVRKTPQMRLETAVYNSAPAVVVYTE-------DHLEGVLLFEVVDDK
MAB_4200|M.abscessus_ATCC_1997      FRKG--MADRRTEIVIANAAPAVAVYAG-------DALEVVITMEIADGK
MSMEG_6817|M.smegmatis_MC2_155      MRR-----DLRFEIVTANGAPAVALRTDE------DQLLGLVTLEIHDGR
MMAR_4487|M.marinum_M               IRKAAT--ELQVELVTCNSAPAVLFYLG-------GQLEGVITLEIVGDK
MAV_1129|M.avium_104                FRKAAEYATLRVDTVTCNGAPAVLLYLG-------DRLEGVITVEIAADK
Mflv_1927|M.gilvum_PYR-GCK          VRLAG--GEARVEPAFYNSAPALVLYTG-------DVLEGVVTFEVADGR
MUL_3630|M.ulcerans_Agy99           AGP-----ERTVLNTLVNGAAGAVISIS-------EQASAVMRFLVRNGR
MLBr_01076|M.leprae_Br4923          PPEFRAAVVLCDIEGLSYEEIGATLGVK--------LGTVRSRIHRGRQA
                                                         .                     .      

Mb3361c|M.bovis_AF2122/97           VCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN
Rv3328c|M.tuberculosis_H37Rv        VCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN
TH_1144|M.thermoresistible__bu      ITNLYATRNPDKLAAVAAPRTITR----------
Mvan_5347|M.vanbaalenii_PYR-1       ITNLYAMRNPDKLTGITIPRKITR----------
MAB_4200|M.abscessus_ATCC_1997      ITRLYAVANPDKLVAAATTRMVSR----------
MSMEG_6817|M.smegmatis_MC2_155      ITSLYAIANPDKLAALDGPRVITR----------
MMAR_4487|M.marinum_M               ITNFYVMRNPDKLTAVARAHEISRG---------
MAV_1129|M.avium_104                ITNFYVMRNPHKLAALATARDVSRG---------
Mflv_1927|M.gilvum_PYR-GCK          ITNFYAMRNPEKLTGVMVARTISR----------
MUL_3630|M.ulcerans_Agy99           IAAIDVLADPQRIATLDISGLSGPGG--------
MLBr_01076|M.leprae_Br4923          LRDYLLTAHPRDGATTDATHVKSA----------
                                    :       .*   .