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LINSDEHAERFTLLRPLLFTIVYEILGSATESDDVLQDSYLRWAQVDLATVRDTKSYLAQLVTRQALKAL RTSVRRREDYIGPWLPEPLLLDEHDGSADVLLAESVSMAMLILLETLTPDERAVFVLREVFGFGYDEIAG AVSKSATAVRQIAHRAREHVHARRKRFDPLDAKESTRIAEQFLLATETGDVEGLMALLAPDATWIADGNG RAGAARRPLTGAGKLARIFAGPFRKGMADRRTEIVIANAAPAVAVYAGDALEVVITMEIADGKITRLYAV ANPDKLVAAATTRMVSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4200 | - | - | 100% (297) | putative sigma factor |
| M. abscessus ATCC 19977 | MAB_1126c | - | 3e-95 | 57.62% (302) | putative sigma factor |
| M. abscessus ATCC 19977 | MAB_3678c | - | 3e-37 | 31.42% (296) | RNA polymerase sigma factor SigJ |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3361c | sigJ | 1e-38 | 31.51% (292) | RNA polymerase sigma factor SigJ |
| M. gilvum PYR-GCK | Mflv_1927 | - | 1e-108 | 66.21% (293) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv3328c | sigJ | 1e-38 | 31.51% (292) | RNA polymerase sigma factor SigJ |
| M. leprae Br4923 | MLBr_01076 | sigE | 6e-05 | 24.14% (145) | RNA polymerase sigma factor SigE |
| M. marinum M | MMAR_4487 | - | 1e-110 | 66.44% (295) | alternative RNA polymerase sigma factor |
| M. avium 104 | MAV_1129 | - | 1e-107 | 68.12% (298) | sigma factor |
| M. smegmatis MC2 155 | MSMEG_6817 | - | 1e-109 | 69.15% (295) | RNA polymerase sigma factor, sigma-70 family protein |
| M. thermoresistible (build 8) | TH_1142 | - | 1e-115 | 70.17% (295) | RNA polymerase sigma factor, sigma-70 family protein |
| M. ulcerans Agy99 | MUL_3630 | - | 5e-27 | 28.67% (286) | alternative RNA polymerase sigma factor SigJ- like |
| M. vanbaalenii PYR-1 | Mvan_5347 | - | 1e-112 | 68.35% (297) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3361c|M.bovis_AF2122/97 -------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLR
Rv3328c|M.tuberculosis_H37Rv -------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLR
MAB_4200|M.abscessus_ATCC_1997 --MIN------SDEHAERFTLLRPLLFTIVYEILGSATESDDVLQDSYLR
MSMEG_6817|M.smegmatis_MC2_155 -MTAR------LDDHTERFTMLRPLLFTIAYEILGSVTEADDVLQDSYLN
TH_1142|M.thermoresistible__bu -MTGSGAPSARGDEHAERFTHLRPLLFTIAYEILGSATEADDVLQESYLR
Mvan_5347|M.vanbaalenii_PYR-1 -MTAS------TDEHGERFTVLRPLLFTIAYEILGSATESEDVLQDSYLR
MMAR_4487|M.marinum_M -MTPPS----HSDEHAERFTLLRPLLFTIAYEILGSATESDDVLQESYLR
MAV_1129|M.avium_104 MMTQAP----TGSEHADRFTLLRPLLFTIAYEMLGSATEADDVLQDSYLR
Mflv_1927|M.gilvum_PYR-GCK -MTAAP-----GDEHAERFTQLRPLLFTIAYEILGSATESDDVLQESYLR
MUL_3630|M.ulcerans_Agy99 ---------MTDPALLARFQAARPRLGALAYRMLGSLADAEDVVQEAWLR
MLBr_01076|M.leprae_Br4923 --------------MGDGIGMEREGRWTGNTQCPLRVVPGD--------E
: * : . . .: .
Mb3361c|M.bovis_AF2122/97 WDSQD------TVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWLPE
Rv3328c|M.tuberculosis_H37Rv WDSPD------TVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWLPE
MAB_4200|M.abscessus_ATCC_1997 WAQVDL-----ATVRDTKSYLAQLVTRQALKALRTSVRRREDYIGPWLPE
MSMEG_6817|M.smegmatis_MC2_155 WAKVDL-----AAVRDTKSYLAQLVTRQALKAQRTSARRRESYVGPWLPE
TH_1142|M.thermoresistible__bu WAEVDL-----AAVRDTKSYLAKLVSRQALNALRAGARRREDYVGPWLPE
Mvan_5347|M.vanbaalenii_PYR-1 WADVDL-----ATVRDTKSYLAQLVTREALNALRARSRRREEYVGPWLPE
MMAR_4487|M.marinum_M WAAVDL-----SAVRDTKSYLAQLVTRQSLNALRAGARRREEYVGPWLPE
MAV_1129|M.avium_104 WSTVDL-----ATVRDTKSYLAQLVTRQALNALRAGARRREEYVGPWLPE
Mflv_1927|M.gilvum_PYR-GCK WAEVDL-----ATVTDTKAYLARLVTRQALNTLRAQSRRREDYVGPWLPE
MUL_3630|M.ulcerans_Agy99 LNATTDRPEGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELVGQLPD
MLBr_01076|M.leprae_Br4923 SPTLDG------RASPEDLIITNLLSPTIMSHPPPS--RDDDWVEPFDAL
:: ::: :. * .
Mb3361c|M.bovis_AF2122/97 PVVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPF
Rv3328c|M.tuberculosis_H37Rv PVVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPF
MAB_4200|M.abscessus_ATCC_1997 P--LLLDEHDGSADVLLAESVSMAMLILLETLTPDERAVFVLREVFGFGY
MSMEG_6817|M.smegmatis_MC2_155 P--LLLDDRDASADVVLAESVSMAMLVVLETLTPDERAVFVLHDVFGFDY
TH_1142|M.thermoresistible__bu P--LLLEERDASADVVLAESVSMAMMVVLESLTPDERAVFVLREVFGFEY
Mvan_5347|M.vanbaalenii_PYR-1 P--LLLDERDASADIVLAESVSMAMLVLLETLTPDERAVFVLREVFGFDY
MMAR_4487|M.marinum_M P--LLLDESDPSADLVLAESVSMAMLVLLETLTPDERAVFVLREVFGFDY
MAV_1129|M.avium_104 P--LLLDEQDPSTDVVLAESISMAMLVLLETLSPDERAVFVLREVFGFDY
Mflv_1927|M.gilvum_PYR-GCK P--LLT-EADPSADVVLAESVSMAMLVVLETLSPDERAVFVLREVFGFGH
MUL_3630|M.ulcerans_Agy99 PIVDGVAAFDPEHHAMLADAVGLALFVVLDTLAPAERLAFVLHDVFAVPF
MLBr_01076|M.leprae_Br4923 Q-----------GTAVFDATGDKATMPSWEELVR-QHAARVYWLAYRLSG
: * : : * :: . * : .
Mb3361c|M.bovis_AF2122/97 AEVAEVLGTSEAAARQLASRARKAVTAQPALIS----GDPDPAHNEVVGR
Rv3328c|M.tuberculosis_H37Rv AEVAEVLGTSEAAARQLASRARKAVTAQPALIS----GDPDPAHNEVVGR
MAB_4200|M.abscessus_ATCC_1997 DEIAGAVSKSATAVRQIAHRAREHVHARRKRFD----PLDAKESTRIAEQ
MSMEG_6817|M.smegmatis_MC2_155 AEISEAVGKSTAAVRQIAHRAREHVHARRKRFD----PVDSDQAAEITQQ
TH_1142|M.thermoresistible__bu GEIATTVGKSVTAVRQIAHRARSHVHARRKRFE----PVDPEVSMEITER
Mvan_5347|M.vanbaalenii_PYR-1 DEIAGAVGRSTQAVRQIAHRAKEHVHARRKRFG----PVDSRRTTQITEQ
MMAR_4487|M.marinum_M DEIADAVGKPAPTVRQVAHRARAHIQARRKKYG----DVDPQRNAQLTAQ
MAV_1129|M.avium_104 DEIAEAVGKPAPTVRQVARRAREHVRARRKRHPGAGQAIDPKRNAELTAQ
Mflv_1927|M.gilvum_PYR-GCK DEIAATLGKSTAAVRQIAHRAREHVQSRRKRFE----PVDPKTSGEITMT
MUL_3630|M.ulcerans_Agy99 DQIAPILERTPEATRKLASRARRRIERAEPFPD-----RDLCAQREVVDA
MLBr_01076|M.leprae_Br4923 NQHDAEDLTQETFIRVFRSVQNYQPGTFEGWLH------------RITTN
: * . . .:.
Mb3361c|M.bovis_AF2122/97 LMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILG
Rv3328c|M.tuberculosis_H37Rv LMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILG
MAB_4200|M.abscessus_ATCC_1997 FLLATETGDVEGLMALLAPDATWIADGNGRAGAARRPLTGAGKLARIFAG
MSMEG_6817|M.smegmatis_MC2_155 FLTAASTGDMAGLVALLAPDVVTITDGGGLPGAARRPLVGAERVAGAIVR
TH_1142|M.thermoresistible__bu FLTAASTGDMDGLLAMLAPDATWTADGGGKATAARRPIVGAEKVAAVILG
Mvan_5347|M.vanbaalenii_PYR-1 FLTAAATGDMEELVSMLAPGATWTADHGGKATAVRRPVVGARKVAAIMAR
MMAR_4487|M.marinum_M FLQTAASGDVEALMAMLAPDATWLADSGGKVSAARKPVVGAERVARAITG
MAV_1129|M.avium_104 FLATAASGDVEALMAMLAPDATWTADSGGVVSAARRPVVGAEKVARAITG
Mflv_1927|M.gilvum_PYR-GCK FFAAAATGDLDALMAMLAPDVVWTADSDGKVSAARRPVEGADKVARLILG
MUL_3630|M.ulcerans_Agy99 FFAAGRSGNFERLVSVLHPDVVLRGDFG--PNTPRFRAQGAATVAKLARS
MLBr_01076|M.leprae_Br4923 LFLDMVRRRARIRMDALPDDYDRVPADEPNPEQIYHDSRLGPDLQAALDS
:: : * . . :
Mb3361c|M.bovis_AF2122/97 LVQRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITVRDG
Rv3328c|M.tuberculosis_H37Rv LVQRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITVRDG
MAB_4200|M.abscessus_ATCC_1997 PFRKG--MADRRTEIVIANAAPAVAVYAG-------DALEVVITMEIADG
MSMEG_6817|M.smegmatis_MC2_155 GMRR-----DLRFEIVTANGAPAVALRTDE------DQLLGLVTLEIHDG
TH_1142|M.thermoresistible__bu IFRAGQRLPDVRIETAIYNCAPAVVVYSR-------DNLEGVFTVEVVDG
Mvan_5347|M.vanbaalenii_PYR-1 VFQAVRKTPQMRLETAVYNSAPAVVVYTE-------DHLEGVLLFEVVDD
MMAR_4487|M.marinum_M LIRKAAT--ELQVELVTCNSAPAVLFYLG-------GQLEGVITLEIVGD
MAV_1129|M.avium_104 LFRKAAEYATLRVDTVTCNGAPAVLLYLG-------DRLEGVITVEIAAD
Mflv_1927|M.gilvum_PYR-GCK FVRLAG--GEARVEPAFYNSAPALVLYTG-------DVLEGVVTFEVADG
MUL_3630|M.ulcerans_Agy99 YAGP-----ERTVLNTLVNGAAGAVISIS-------EQASAVMRFLVRNG
MLBr_01076|M.leprae_Br4923 LPPEFRAAVVLCDIEGLSYEEIGATLGVK----------LGTVRSRIHRG
. : .
Mb3361c|M.bovis_AF2122/97 K--VCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN
Rv3328c|M.tuberculosis_H37Rv K--VCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN
MAB_4200|M.abscessus_ATCC_1997 K--ITRLYAVANPDKLVAAATTRMVSR----------
MSMEG_6817|M.smegmatis_MC2_155 R--ITSLYAIANPDKLAALDGPRVITR----------
TH_1142|M.thermoresistible__bu R--ITHFYAVRNPEKLAAVDTPRQISR----------
Mvan_5347|M.vanbaalenii_PYR-1 K--ITNLYAMRNPDKLTGITIPRKITR----------
MMAR_4487|M.marinum_M K--ITNFYVMRNPDKLTAVARAHEISRG---------
MAV_1129|M.avium_104 K--ITNFYVMRNPHKLAALATARDVSRG---------
Mflv_1927|M.gilvum_PYR-GCK R--ITNFYAMRNPEKLTGVMVARTISR----------
MUL_3630|M.ulcerans_Agy99 R--IAAIDVLADPQRIATLDISGLSGPGG--------
MLBr_01076|M.leprae_Br4923 RQALRDYLLTAHPRDGATTDATHVKSA----------
: : .* .