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TASTDEHGERFTVLRPLLFTIAYEILGSATESEDVLQDSYLRWADVDLATVRDTKSYLAQLVTREALNAL RARSRRREEYVGPWLPEPLLLDERDASADIVLAESVSMAMLVLLETLTPDERAVFVLREVFGFDYDEIAG AVGRSTQAVRQIAHRAKEHVHARRKRFGPVDSRRTTQITEQFLTAAATGDMEELVSMLAPGATWTADHGG KATAVRRPVVGARKVAAIMARVFQAVRKTPQMRLETAVYNSAPAVVVYTEDHLEGVLLFEVVDDKITNLY AMRNPDKLTGITIPRKITR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_5347 | - | - | 100% (300) | ECF subfamily RNA polymerase sigma-24 factor |
M. vanbaalenii PYR-1 | Mvan_4806 | - | e-112 | 70.17% (295) | ECF subfamily RNA polymerase sigma-24 factor |
M. vanbaalenii PYR-1 | Mvan_4999 | - | 1e-41 | 41.02% (256) | ECF subfamily RNA polymerase sigma-24 factor |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3361c | sigJ | 5e-40 | 32.87% (289) | RNA polymerase sigma factor SigJ |
M. gilvum PYR-GCK | Mflv_1927 | - | 1e-111 | 68.79% (298) | ECF subfamily RNA polymerase sigma-24 factor |
M. tuberculosis H37Rv | Rv3328c | sigJ | 5e-40 | 32.87% (289) | RNA polymerase sigma factor SigJ |
M. leprae Br4923 | MLBr_01076 | sigE | 1e-06 | 24.65% (142) | RNA polymerase sigma factor SigE |
M. abscessus ATCC 19977 | MAB_4200 | - | 1e-112 | 68.35% (297) | putative sigma factor |
M. marinum M | MMAR_4487 | - | 1e-113 | 68.24% (296) | alternative RNA polymerase sigma factor |
M. avium 104 | MAV_1129 | - | 1e-110 | 66.44% (298) | sigma factor |
M. smegmatis MC2 155 | MSMEG_5444 | - | 1e-107 | 65.32% (297) | RNA polymerase sigma-70 factor protein |
M. thermoresistible (build 8) | TH_1142 | - | 1e-124 | 72.58% (299) | RNA polymerase sigma factor, sigma-70 family protein |
M. ulcerans Agy99 | MUL_3630 | - | 8e-30 | 31.51% (292) | alternative RNA polymerase sigma factor SigJ- like |
CLUSTAL 2.0.9 multiple sequence alignment Mb3361c|M.bovis_AF2122/97 ---------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAW Rv3328c|M.tuberculosis_H37Rv ---------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAW MUL_3630|M.ulcerans_Agy99 -----------MTDPALLARFQAARPRLGALAYRMLGSLADAEDVVQEAW Mvan_5347|M.vanbaalenii_PYR-1 ---MTAS------TDEHGERFTVLRPLLFTIAYEILGSATESEDVLQDSY TH_1142|M.thermoresistible__bu ---MTGSGAPSARGDEHAERFTHLRPLLFTIAYEILGSATEADDVLQESY MMAR_4487|M.marinum_M ---MTPPSH----SDEHAERFTLLRPLLFTIAYEILGSATESDDVLQESY MAV_1129|M.avium_104 --MMTQAPT----GSEHADRFTLLRPLLFTIAYEMLGSATEADDVLQDSY MAB_4200|M.abscessus_ATCC_1997 ------MIN----SDEHAERFTLLRPLLFTIVYEILGSATESDDVLQDSY Mflv_1927|M.gilvum_PYR-GCK ---MTAAP-----GDEHAERFTQLRPLLFTIAYEILGSATESDDVLQESY MSMEG_5444|M.smegmatis_MC2_155 MNNPSAGN-----STEHAERFTALRPLLFTIAYEILGTATESDDVLQESY MLBr_01076|M.leprae_Br4923 ----------------MGDGIGMEREGRWTGNTQCPLRVVPGD---ESPT : * : . . .: :.. Mb3361c|M.bovis_AF2122/97 LRWDSQD------TVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWL Rv3328c|M.tuberculosis_H37Rv LRWDSPD------TVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWL MUL_3630|M.ulcerans_Agy99 LRLNATTDRPEGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELVGQL Mvan_5347|M.vanbaalenii_PYR-1 LRWADVD-----LATVRDTKSYLAQLVTREALNALRARSRRREEYVGPWL TH_1142|M.thermoresistible__bu LRWAEVD-----LAAVRDTKSYLAKLVSRQALNALRAGARRREDYVGPWL MMAR_4487|M.marinum_M LRWAAVD-----LSAVRDTKSYLAQLVTRQSLNALRAGARRREEYVGPWL MAV_1129|M.avium_104 LRWSTVD-----LATVRDTKSYLAQLVTRQALNALRAGARRREEYVGPWL MAB_4200|M.abscessus_ATCC_1997 LRWAQVD-----LATVRDTKSYLAQLVTRQALKALRTSVRRREDYIGPWL Mflv_1927|M.gilvum_PYR-GCK LRWAEVD-----LATVTDTKAYLARLVTRQALNTLRAQSRRREDYVGPWL MSMEG_5444|M.smegmatis_MC2_155 LRWAEVD-----LATVTDTKAYLAKLVTRQSLNALRARSRLREEYVGPWL MLBr_01076|M.leprae_Br4923 LDGRASP-----------EDLIITNLLSPTIMSHPPPS--RDDDWVEPFD * :: ::: :. Mb3361c|M.bovis_AF2122/97 PEPVVTGLDATDPLAAVVAAEDARFAAMVVLERLR--PDQRVAFVLHDGF Rv3328c|M.tuberculosis_H37Rv PEPVVTGLDATDPLAAVVAAEDARFAAMVVLERLR--PDQRVAFVLHDGF MUL_3630|M.ulcerans_Agy99 PDPIVDGVAAFDPEHHAMLADAVGLALFVVLDTLA--PAERLAFVLHDVF Mvan_5347|M.vanbaalenii_PYR-1 PEPLL--LDERDASADIVLAESVSMAMLVLLETLT--PDERAVFVLREVF TH_1142|M.thermoresistible__bu PEPLL--LEERDASADVVLAESVSMAMMVVLESLT--PDERAVFVLREVF MMAR_4487|M.marinum_M PEPLL--LDESDPSADLVLAESVSMAMLVLLETLT--PDERAVFVLREVF MAV_1129|M.avium_104 PEPLL--LDEQDPSTDVVLAESISMAMLVLLETLS--PDERAVFVLREVF MAB_4200|M.abscessus_ATCC_1997 PEPLL--LDEHDGSADVLLAESVSMAMLILLETLT--PDERAVFVLREVF Mflv_1927|M.gilvum_PYR-GCK PEPLL--TEA-DPSADVVLAESVSMAMLVVLETLS--PDERAVFVLREVF MSMEG_5444|M.smegmatis_MC2_155 PEPLL--VAE-DASSDVVLAESVSMAMLVVLETLT--PDERAVFVLHDVF MLBr_01076|M.leprae_Br4923 -----------ALQGTAVFDATGDKATMPSWEELVRQHAARVYWLAYRLS : * : : * * :: Mb3361c|M.bovis_AF2122/97 AVPFAEVAEVLGTSEAAARQLASRARKAVTAQPALISGDP----DPAHNE Rv3328c|M.tuberculosis_H37Rv AVPFAEVAEVLGTSEAAARQLASRARKAVTAQPALISGDP----DPAHNE MUL_3630|M.ulcerans_Agy99 AVPFDQIAPILERTPEATRKLASRARRRIERAEPFPDRD-----LCAQRE Mvan_5347|M.vanbaalenii_PYR-1 GFDYDEIAGAVGRSTQAVRQIAHRAKEHVHARRKRFG----PVDSRRTTQ TH_1142|M.thermoresistible__bu GFEYGEIATTVGKSVTAVRQIAHRARSHVHARRKRFE----PVDPEVSME MMAR_4487|M.marinum_M GFDYDEIADAVGKPAPTVRQVAHRARAHIQARRKKYG----DVDPQRNAQ MAV_1129|M.avium_104 GFDYDEIAEAVGKPAPTVRQVARRAREHVRARRKRHPGAGQAIDPKRNAE MAB_4200|M.abscessus_ATCC_1997 GFGYDEIAGAVSKSATAVRQIAHRAREHVHARRKRFD----PLDAKESTR Mflv_1927|M.gilvum_PYR-GCK GFGHDEIAATLGKSTAAVRQIAHRAREHVQSRRKRFE----PVDPKTSGE MSMEG_5444|M.smegmatis_MC2_155 GFSHDEIASTIGKSAAAVRQMAHRARNHVQARRKRFE----PVDPQVSME MLBr_01076|M.leprae_Br4923 GNQHDAEDLTQETFIRVFRSVQNYQPGTFEG---------------WLHR . . . *.: . . Mb3361c|M.bovis_AF2122/97 VVGRLMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVR Rv3328c|M.tuberculosis_H37Rv VVGRLMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVR MUL_3630|M.ulcerans_Agy99 VVDAFFAAGRSGNFERLVSVLHPDVVLRGDFGPNTPRFR--AQGAATVAK Mvan_5347|M.vanbaalenii_PYR-1 ITEQFLTAAATGDMEELVSMLAPGATWTADHGGKATAVRRPVVGARKVAA TH_1142|M.thermoresistible__bu ITERFLTAASTGDMDGLLAMLAPDATWTADGGGKATAARRPIVGAEKVAA MMAR_4487|M.marinum_M LTAQFLQTAASGDVEALMAMLAPDATWLADSGGKVSAARKPVVGAERVAR MAV_1129|M.avium_104 LTAQFLATAASGDVEALMAMLAPDATWTADSGGVVSAARRPVVGAEKVAR MAB_4200|M.abscessus_ATCC_1997 IAEQFLLATETGDVEGLMALLAPDATWIADGNGRAGAARRPLTGAGKLAR Mflv_1927|M.gilvum_PYR-GCK ITMTFFAAAATGDLDALMAMLAPDVVWTADSDGKVSAARRPVEGADKVAR MSMEG_5444|M.smegmatis_MC2_155 ITQRFFTAASTGDIDALMELLAPDVVWTADSAGKRSAARRPVSGADAVAR MLBr_01076|M.leprae_Br4923 ITTNLFLDMVRRRARIRMDALPDDYDRVPADEPNPEQIYHDSRLGPDLQA :. :: : * . . : Mb3361c|M.bovis_AF2122/97 FILGLVQRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAIT Rv3328c|M.tuberculosis_H37Rv FILGLVQRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAIT MUL_3630|M.ulcerans_Agy99 LARSYAGPERTVLN-----TLVNGAAGAVIS-------ISEQASAVMRFL Mvan_5347|M.vanbaalenii_PYR-1 IMARVFQAVRKTPQMRLETAVYNSAPAVVVYT-------EDHLEGVLLFE TH_1142|M.thermoresistible__bu VILGIFRAGQRLPDVRIETAIYNCAPAVVVYS-------RDNLEGVFTVE MMAR_4487|M.marinum_M AITGLIRKAAT--ELQVELVTCNSAPAVLFYL-------GGQLEGVITLE MAV_1129|M.avium_104 AITGLFRKAAEYATLRVDTVTCNGAPAVLLYL-------GDRLEGVITVE MAB_4200|M.abscessus_ATCC_1997 IFAGPFRKGMA--DRRTEIVIANAAPAVAVYA-------GDALEVVITME Mflv_1927|M.gilvum_PYR-GCK LILGFVRLAGG--EARVEPAFYNSAPALVLYT-------GDVLEGVVTFE MSMEG_5444|M.smegmatis_MC2_155 LVSGLVRLGGE--GARVEPAMYNNAPALKLYL-------GDSFEGVITIE MLBr_01076|M.leprae_Br4923 ALDSLPPEFRAAVVLCDIEGLSYEEIGATLGV--------KLGTVRSRIH . . Mb3361c|M.bovis_AF2122/97 VRDGKVCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN Rv3328c|M.tuberculosis_H37Rv VRDGKVCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN MUL_3630|M.ulcerans_Agy99 VRNGRIAAIDVLADPQRIATLDISG-LSGPGG------- Mvan_5347|M.vanbaalenii_PYR-1 VVDDKITNLYAMRNPDKLTGITIPRKITR---------- TH_1142|M.thermoresistible__bu VVDGRITHFYAVRNPEKLAAVDTPRQISR---------- MMAR_4487|M.marinum_M IVGDKITNFYVMRNPDKLTAVARAHEISRG--------- MAV_1129|M.avium_104 IAADKITNFYVMRNPHKLAALATARDVSRG--------- MAB_4200|M.abscessus_ATCC_1997 IADGKITRLYAVANPDKLVAAATTRMVSR---------- Mflv_1927|M.gilvum_PYR-GCK VADGRITNFYAMRNPEKLTGVMVARTISR---------- MSMEG_5444|M.smegmatis_MC2_155 IVDGRITHFYAMRNPDKLAGVDIPRVISR---------- MLBr_01076|M.leprae_Br4923 RGRQALRDYLLTAHPRDGATTDATHVKSA---------- : .* . :