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M. thermoresistible (build 8) TH_0884 (-)

annotation: conserved hypothetical protein
coordinates: 1790144 - 1791079
length: 312

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0884--100% (312)conserved hypothetical protein
M. thermoresistible (build 8)TH_3968-5e-6241.75% (285) PUTATIVE conserved hypothetical proline and alanine rich
M. thermoresistible (build 8)TH_3875-9e-0529.76% (168) PUTATIVE Cobyrinic acid a,c-diamide synthase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0543-1e-12872.90% (310) hypothetical protein Mb0543
M. gilvum PYR-GCKMflv_0048-1e-13273.73% (316) hypothetical protein Mflv_0048
M. tuberculosis H37RvRv0530-1e-12872.90% (310) hypothetical protein Rv0530
M. leprae Br4923MLBr_00048-1e-5637.01% (308) hypothetical protein MLBr_00048
M. abscessus ATCC 19977MAB_3972c-1e-13576.47% (306) hypothetical protein MAB_3972c
M. marinum MMMAR_0876-1e-12669.68% (310) hypothetical protein MMAR_0876
M. avium 104MAV_4615-1e-12471.38% (304) hypothetical protein MAV_4615
M. smegmatis MC2 155MSMEG_0975-1e-14182.27% (299) hypothetical protein MSMEG_0975
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0870-1e-12672.84% (313) hypothetical protein Mvan_0870

CLUSTAL 2.0.9 multiple sequence alignment


Mb0543|M.bovis_AF2122/97            --------------------------------------------------
Rv0530|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0876|M.marinum_M               --------------------------------------------------
MAV_4615|M.avium_104                --------------------------------------------------
TH_0884|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0975|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0870|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_3972c|M.abscessus_ATCC_199      --------------------------------------------------
MLBr_00048|M.leprae_Br4923          MAADYDKLFRLDDGAYASPDQAAEQLFDDAPLYPPPIIPTCTTTPNGEVA
                                                                                      

Mb0543|M.bovis_AF2122/97            --------------------------------------------------
Rv0530|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_0876|M.marinum_M               --------------------------------------------------
MAV_4615|M.avium_104                --------------------------------------------------
TH_0884|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0975|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0870|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_3972c|M.abscessus_ATCC_199      ------MSDYPAHRAPDGPSPYAADEAQGGPTAPPWAAQEPAQPVMYGQS
MLBr_00048|M.leprae_Br4923          SPMPDWSEQLPPNPPAASKSPLPPMPIGSSVQPPPASSESPRAPMPVSAP
                                                                                      

Mb0543|M.bovis_AF2122/97            -------------------MLVTEHPRTGVGAPDS----GNGGTDHPTVQ
Rv0530|M.tuberculosis_H37Rv         -------------------MLVTEHPRTGVGAPDS----GNGGTDHPTVQ
MMAR_0876|M.marinum_M               -------------------MDVSDHPSAGVGASNAY--QGEGGKDHPTIQ
MAV_4615|M.avium_104                ---------------------MSEHPTAGVGAPEE-----------QTTQ
TH_0884|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0975|M.smegmatis_MC2_155      ---------------------------------------MSASSEHPVPD
Mflv_0048|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0870|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_3972c|M.abscessus_ATCC_199      TPQQPHEMTQQFQAVPFQDPFAPQQDIAGLGHDPAVPSLNSLGGSFAPLD
MLBr_00048|M.leprae_Br4923          PRSPAASLMPISEPPQWPPAEAPEHQFAKAEPPSVPIPINEPSPAKPATP
                                                                                      

Mb0543|M.bovis_AF2122/97            LPPVPS-------VGAPP---AAAGGETPTRSVAGFRTQR----------
Rv0530|M.tuberculosis_H37Rv         LPPVPS-------VGAPP---AAAGGETPTRSVAGFRTQR----------
MMAR_0876|M.marinum_M               LPPVPHQ---PPQLGEPP---VAGGSDAPTRAFAGFRTERRSAARAEGAE
MAV_4615|M.avium_104                IPPAAAAGDDKKDAAEPQ---PEPGGDAPTKAFAGFRTERRVPEREPAPP
TH_0884|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0975|M.smegmatis_MC2_155      SVDVPAP------EHPAA---ETPEAPSVFAPVPGFRGQQRFSDPAQAGV
Mflv_0048|M.gilvum_PYR-GCK          ---------------------------------MSFRAQQRFSD-----P
Mvan_0870|M.vanbaalenii_PYR-1       -----------------------------MDAPGSFRAQQRFSD-----P
MAB_3972c|M.abscessus_ATCC_199      FTPSGSQ------EAGDP---TAVGAAGSSGGPGGFRADNRFSDSGEQ-P
MLBr_00048|M.leprae_Br4923          MPMTPIDGSQRTPVTSPEPSLAEFEAQPPATPKPSLLPRPMSSPPEAPRP
                                                                                      

Mb0543|M.bovis_AF2122/97            ---------------------LDPTAYGAYYSGPDEGPASPAERPPY---
Rv0530|M.tuberculosis_H37Rv         ---------------------LDPTAYGAYYSGPDEGPASPAERPPY---
MMAR_0876|M.marinum_M               APDVAQWESGPDTGPVAGLPRVDPTAYGAYYNGPPEPPAEPQYRP-----
MAV_4615|M.avium_104                TAPRPGGMPPWDSTPVTGIPRVDPTAYGAYYAGPDAPPTQIQGPPP----
TH_0884|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0975|M.smegmatis_MC2_155      STPLP---AEWTA---------PTPPHGIPVSAPQTAQTPPQNSHQPMAS
Mflv_0048|M.gilvum_PYR-GCK          MAPVP---AEWTA---------PTPPEGVVPVVAAATPSTE---------
Mvan_0870|M.vanbaalenii_PYR-1       MAPVP---AEWTA---------PTPPEGAPPVVTADP-------------
MAB_3972c|M.abscessus_ATCC_199      AQPTPFTADRWAS---------DTPPSGIPQQAQQPPVGGSRYYTPVGGQ
MLBr_00048|M.leprae_Br4923          SANQHSRHARRGHHHRDETQQANPASATEPMIAPRARTAELRQAPHAAAE
                                                                                      

Mb0543|M.bovis_AF2122/97            ------------------RLEPVPHTPYPELATTTLLRPVKPP---PSEG
Rv0530|M.tuberculosis_H37Rv         ------------------RLEPVPHTPYPELATTTLLRPVKPP---PSEG
MMAR_0876|M.marinum_M               --------------------ESVPQTPYPELSTSMLLRPVKSP---PTEG
MAV_4615|M.avium_104                ------------------RQEHLPHTPYPELSTGMLLRPVQPP---PSEG
TH_0884|M.thermoresistible__bu      ----------------------------VDLSTTALLGQRRPA---PSRG
MSMEG_0975|M.smegmatis_MC2_155      GLPPLPPAPLTPPAAAAEQPPADFATPYEDLTTTALLGRRKSP---PTAG
Mflv_0048|M.gilvum_PYR-GCK          ------------------------LVPYRELSTVALLGALPKA---PSAG
Mvan_0870|M.vanbaalenii_PYR-1       -------------------------APYLDLSTVALLGNASRG---PSAG
MAB_3972c|M.abscessus_ATCC_199      ------------QTGVGGQIRPELPPSSRDLSTSALLRPHKPA---PSAG
MLBr_00048|M.leprae_Br4923          PAPTQHLTRPDGLVSHRTALHDSTATSAIGVQTGRSTGAKKPSKVVAKRG
                                                                  : *             .. *

Mb0543|M.bovis_AF2122/97            WRRLLYLLSGRLINAGEGPRAAHLNDLVAQVNRPLRGCYRIAVLSLKGGV
Rv0530|M.tuberculosis_H37Rv         WRRLLYLLSGRLINAGEGPRAAHLNDLVAQVNRPLRGCYRIAVLSLKGGV
MMAR_0876|M.marinum_M               WRRLVYVLSGQLINLGESPRATRYNNLVAQINRPMRGCYRIALVSLKGGV
MAV_4615|M.avium_104                WRLLLYKLSGGLINLGESPRAARYNNLVAQVNRPLRGSYRVAFLSLKGGV
TH_0884|M.thermoresistible__bu      WRRWLYRATFRTVNLGESPKVARHNELLNRVRHPLQDCYRIAVLSLKGGV
MSMEG_0975|M.smegmatis_MC2_155      WRRWLYLASFKQVNVGESPKVTHRQSLVSQVSHPLQGCYRIAVLSLKGGV
Mflv_0048|M.gilvum_PYR-GCK          WRKWVYRASGRLINPGESPKVIRHDDLLARVQQPLQGCYRVAMLSQKGGV
Mvan_0870|M.vanbaalenii_PYR-1       WRKWLYWGSGRLIDVGESPKVIRRNALVAQVQRPLRDCYRIAMLSQKGGV
MAB_3972c|M.abscessus_ATCC_199      WRKTVYRASFGTINLGEGTKKTEENDLIAQVNQPLQGCYKIALLSLKGGV
MLBr_00048|M.leprae_Br4923          WRHWVHTVTR--INLGLSPDERYELDLRTRVRRPPRGSYQIGILGLKGGA
                                    **  ::  :   :: * ..       *  :: :* :..*::..:. ***.

Mb0543|M.bovis_AF2122/97            GKTTITATLGATFADLRGDRVVAVDANPDRGTLSQKVPLETPATVRHLLR
Rv0530|M.tuberculosis_H37Rv         GKTTITATLGATFADLRGDRVVAVDANPDRGTLSQKVPLETPATVRHLLR
MMAR_0876|M.marinum_M               GKTTITATLGSTFASVRGDRVVAVDANPDRGTLSQKVPLETPATVRHLIR
MAV_4615|M.avium_104                GKTTIAATLGATFASIRGDRVVAVDANPDRGTLSQKIPLETAATVRQLLH
TH_0884|M.thermoresistible__bu      GKTTITATLGSTFGSARGDRVVAVDANPDRGTLSQKVPLQTRATVRDLLR
MSMEG_0975|M.smegmatis_MC2_155      GKTTITATLGSTFASIRGDRVIAVDANPDRGTLSQKVPLETAATVRHLLR
Mflv_0048|M.gilvum_PYR-GCK          GKTTITATLGATFAGARGDRVIAVDANPDRGTLSQKVPVETPATVRHLLR
Mvan_0870|M.vanbaalenii_PYR-1       GKTTITATLGATFATTRGDRVIAVDANPDRGTLSQKVPLETPATVRHLLR
MAB_3972c|M.abscessus_ATCC_199      GKTTVTATLGATFASIRGDRVIAVDANPDRGTLSQKVPLETPATVRHLLR
MLBr_00048|M.leprae_Br4923          GKTTVTVTLGSMFARVRNDRILVVDADTSCGNLADRAGRFSEANIADLLA
                                    ****::.***: *.  *.**::.***:.. *.*:::    : *.: .*: 

Mb0543|M.bovis_AF2122/97            DADGIERYSDVRGYTSKGPSGLEVLASDSDPASSDAFSADDYTRTLDILE
Rv0530|M.tuberculosis_H37Rv         DADGIERYSDVRGYTSKGPSGLEVLASDSDPASSDAFSADDYTRTLDILE
MMAR_0876|M.marinum_M               DAEGIERYSDVRGYTSQAKNGFEVLASDTDPAASEAFSADDYTRTLDILE
MAV_4615|M.avium_104                DAGTIERYSDVRRYTSKGPSGLEVLASETDPAVSEAFSADDYVRILDILE
TH_0884|M.thermoresistible__bu      DADRIQTYSDMRAYTSQSPSRLEVLASESDPAVSEAFSSDDYTRTLRVLE
MSMEG_0975|M.smegmatis_MC2_155      DAEGIERYSDVRAYTSQGPSRLEVLASESDPAVSEAFSSEDYLRTLEVLE
Mflv_0048|M.gilvum_PYR-GCK          DAEGVSAYSDVRRYTSQGPSRLEVLASESDPAVSEAFSATDYVRALNILE
Mvan_0870|M.vanbaalenii_PYR-1       DAEGIAAYSDVRQYTSQGPSRLEVLASESDPAVSEAFSAADYCRAVDVLE
MAB_3972c|M.abscessus_ATCC_199      DANSIQRYSDVRSYTSQGPSRLEVLASESDPAVSEAFSAEDYSRTLEILE
MLBr_00048|M.leprae_Br4923          DKD-VKSYNDIRTHTSVNAVNLEVLPAAEYSTAQHALSGEDWNFAAATVS
                                    *   :  *.*:* :**     :***.:   .: ..*:*. *:      :.

Mb0543|M.bovis_AF2122/97            RFYGLVLTDCGTGLLHSAMSAVLPRSDVLVVVSSGSIDGARSAAATLDWL
Rv0530|M.tuberculosis_H37Rv         RFYGLVLTDCGTGLLHSAMSAVLPRSDVLVVVSSGSIDGARSAAATLDWL
MMAR_0876|M.marinum_M               RFYGLVLTDCGTGLLHSAMSAILAKSDILIVVSSGSIDGARSASATLDWL
MAV_4615|M.avium_104                RFYGLVLTDCGPGLLHSVMKSVLDKADALVVVSSASIDGARSASATLDWL
TH_0884|M.thermoresistible__bu      RFYSLVLTDCGTGLIHSAMSAVLANADVLIVISSGSVDGARSAAATLDWL
MSMEG_0975|M.smegmatis_MC2_155      RFYSLVLTDCGTGLIHSAMSAVLSKADVLIVVSSGSVDGARSAAATLDWL
Mflv_0048|M.gilvum_PYR-GCK          RFYSMVLTDCGTGMLHSAMSAVIDKADVLVVISSGSADGARSASATLDWL
Mvan_0870|M.vanbaalenii_PYR-1       RFYSVVLTDCGTGMLHSAMSGVIDKADVLVVISSGSVDGARSASATLDWL
MAB_3972c|M.abscessus_ATCC_199      KFYSVVLTDCGTGLMHSAMSSVLEQADTLVVISSGSVDGARSASATLDWL
MLBr_00048|M.leprae_Br4923          KYYNVMLADCGVGLFDPVTRGVLSTASGVVIVTSTSVDAARQAAIALDWL
                                    ::*.::*:*** *::...  .::  :. :::::* * *.**.*: :****

Mb0543|M.bovis_AF2122/97            QAHGHDDQVRNSIAVVNAVRPR--------AGKVDVGKVVEHFSRRCR--
Rv0530|M.tuberculosis_H37Rv         QAHGHDDQVRNSIAVVNAVRPR--------AGKVDVGKVVEHFSRRCR--
MMAR_0876|M.marinum_M               EAHGYEELVRNSIAVINAVRPR--------SSKVDMQKVIDHFARRCR--
MAV_4615|M.avium_104                DAHGHEDLVRNSIAVINGVRPR--------PGKVDMNKVIDHFSRRCR--
TH_0884|M.thermoresistible__bu      DAHGHQDMVRNSIAVINAVRPR--------SGKVDLQKVVDHFSRRCR--
MSMEG_0975|M.smegmatis_MC2_155      DAHGHQDLVRNSVAVLNAVRPR--------AGKVDLSKVVDHFSRRCR--
Mflv_0048|M.gilvum_PYR-GCK          DAHGHDDMVRNSIAVINAVRPRGRRGTSRGTAKVDLDKIVDHFTRRCR--
Mvan_0870|M.vanbaalenii_PYR-1       DAHGHGDMVGNSIAVINGVRRGARKGAGKGTAKVDLNKVVDHFARRCR--
MAB_3972c|M.abscessus_ATCC_199      DAHGHRELVRRSIAVINAVRPR--------SGKVDMQKVVDHFSRRCR--
MLBr_00048|M.leprae_Br4923          RHNGYQDLLSRACVVINHVMPK--------EPNIASKDLVQQFEQQIQPG
                                      :*: : : .: .*:* *             ::   .::::* :: :  

Mb0543|M.bovis_AF2122/97            AVRVVPFDPHLEEGAEIALDRLRRETREALTELAAVVAAGFP--------
Rv0530|M.tuberculosis_H37Rv         AVRVVPFDPHLEEGAEIALDRLRRETREALTELAAVVAAGFP--------
MMAR_0876|M.marinum_M               AVRLVPFDPHLEEGAEIVLDRMKRETREALAELAAVVAEGFG--------
MAV_4615|M.avium_104                AVQLVPFDPHLEEGAEIDLDRLRRGTREALTELAAIVADGFP--------
TH_0884|M.thermoresistible__bu      AVKMVPFDPHLEEGAEIDLDQLKPQTRQALLELAAVVADGFP--------
MSMEG_0975|M.smegmatis_MC2_155      AVRLVPFDPHLEEGAEISLDRLKPKTREALLELAAVVAGDFGSDRTGALG
Mflv_0048|M.gilvum_PYR-GCK          AVCQVPFDAHLEEGAEISLDRLRPQTRESLLELAAAVADGFP--------
Mvan_0870|M.vanbaalenii_PYR-1       AVCQVPFDPHLEEGAEISLDRLRADTRESLLELAAAVADGFP--------
MAB_3972c|M.abscessus_ATCC_199      AVRLVPFDPHLEEGAEISLDRLRPQTRRALIELAAVVAQGFT--------
MLBr_00048|M.leprae_Br4923          RVVVLPWDKHIAAGTEIRLDRLDPLYRRRILELAAALSDDFER-------
                                     *  :*:* *:  *:** **::    *. : **** :: .*         

Mb0543|M.bovis_AF2122/97            -----GDPRRCKPSFT
Rv0530|M.tuberculosis_H37Rv         -----GDPRRCKPSFT
MMAR_0876|M.marinum_M               -----PDQRRSSPSFG
MAV_4615|M.avium_104                -----GAQRN-PGVLG
TH_0884|M.thermoresistible__bu      -----GAQQLQSPPF-
MSMEG_0975|M.smegmatis_MC2_155      GADSAGSRRIADPRV-
Mflv_0048|M.gilvum_PYR-GCK          -----GARNRSDPAD-
Mvan_0870|M.vanbaalenii_PYR-1       -----GAR-RTDPVG-
MAB_3972c|M.abscessus_ATCC_199      -----GTQRQQQTFQG
MLBr_00048|M.leprae_Br4923          ------AGRH------