For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VSASSEHPVPDSVDVPAPEHPAAETPEAPSVFAPVPGFRGQQRFSDPAQAGVSTPLPAEWTAPTPPHGIP VSAPQTAQTPPQNSHQPMASGLPPLPPAPLTPPAAAAEQPPADFATPYEDLTTTALLGRRKSPPTAGWRR WLYLASFKQVNVGESPKVTHRQSLVSQVSHPLQGCYRIAVLSLKGGVGKTTITATLGSTFASIRGDRVIA VDANPDRGTLSQKVPLETAATVRHLLRDAEGIERYSDVRAYTSQGPSRLEVLASESDPAVSEAFSSEDYL RTLEVLERFYSLVLTDCGTGLIHSAMSAVLSKADVLIVVSSGSVDGARSAAATLDWLDAHGHQDLVRNSV AVLNAVRPRAGKVDLSKVVDHFSRRCRAVRLVPFDPHLEEGAEISLDRLKPKTREALLELAAVVAGDFGS DRTGALGGADSAGSRRIADPRV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0975 | - | - | 100% (442) | hypothetical protein MSMEG_0975 |
| M. smegmatis MC2 155 | MSMEG_0067 | - | 5e-69 | 36.87% (434) | hypothetical protein MSMEG_0067 |
| M. smegmatis MC2 155 | MSMEG_0053 | - | 4e-52 | 32.94% (428) | hypothetical protein MSMEG_0053 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0543 | - | 1e-140 | 62.91% (426) | hypothetical protein Mb0543 |
| M. gilvum PYR-GCK | Mflv_0048 | - | 1e-140 | 64.89% (393) | hypothetical protein Mflv_0048 |
| M. tuberculosis H37Rv | Rv0530 | - | 1e-140 | 62.91% (426) | hypothetical protein Rv0530 |
| M. leprae Br4923 | MLBr_00048 | - | 1e-59 | 32.75% (455) | hypothetical protein MLBr_00048 |
| M. abscessus ATCC 19977 | MAB_3972c | - | 1e-142 | 68.39% (386) | hypothetical protein MAB_3972c |
| M. marinum M | MMAR_0876 | - | 1e-139 | 60.66% (427) | hypothetical protein MMAR_0876 |
| M. avium 104 | MAV_4615 | - | 1e-130 | 58.20% (445) | hypothetical protein MAV_4615 |
| M. thermoresistible (build 8) | TH_0884 | - | 1e-141 | 82.27% (299) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0022 | pstP | 9e-07 | 33.68% (95) | serine/threonine phosphatase PstP |
| M. vanbaalenii PYR-1 | Mvan_0870 | - | 1e-138 | 65.42% (402) | hypothetical protein Mvan_0870 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0543|M.bovis_AF2122/97 --------------------------------------------------
Rv0530|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0876|M.marinum_M --------------------------------------------------
MAV_4615|M.avium_104 --------------------------------------------------
MSMEG_0975|M.smegmatis_MC2_155 --------------------------------------------------
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0870|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3972c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00048|M.leprae_Br4923 MAADYDKLFRLDDGAYASPDQAAEQLFDDAPLYPPPIIPTCTTTPNGEVA
MUL_0022|M.ulcerans_Agy99 --------------------------------------------------
Mb0543|M.bovis_AF2122/97 --------------------------------------------------
Rv0530|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0876|M.marinum_M --------------------------------------------------
MAV_4615|M.avium_104 --------------------------------------------------
MSMEG_0975|M.smegmatis_MC2_155 --------------------------------------------------
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0870|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3972c|M.abscessus_ATCC_199 ----------------------MSDYPAHRAPDGPSPYAADEAQGGPTAP
MLBr_00048|M.leprae_Br4923 SPMPDWSEQLPPNPPAASKSPLPPMPIGSSVQPPPASSESPRAPMPVSAP
MUL_0022|M.ulcerans_Agy99 ------------------------------MTLVLRYAARSDRGLVRANN
Mb0543|M.bovis_AF2122/97 -----------------------------------MLVTEHPRTGVGAPD
Rv0530|M.tuberculosis_H37Rv -----------------------------------MLVTEHPRTGVGAPD
MMAR_0876|M.marinum_M -----------------------------------MDVSDHPSAGVGASN
MAV_4615|M.avium_104 -------------------------------------MSEHPTAGVGAPE
MSMEG_0975|M.smegmatis_MC2_155 --------------------------------------------------
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0870|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3972c|M.abscessus_ATCC_199 PWAAQEPAQPVMYGQSTPQQPHEMTQQFQAVPFQDPFAPQQDIAGLGHDP
MLBr_00048|M.leprae_Br4923 PRSPAASLMPISEPPQWPPAEAPEHQFAKAEPPSVPIPINEPSPAKPATP
MUL_0022|M.ulcerans_Agy99 EDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPGGDLLAKL
Mb0543|M.bovis_AF2122/97 S----GNGGTDHPTVQLPPVPS-------VGAPPAAAGGETPTRSVAGFR
Rv0530|M.tuberculosis_H37Rv S----GNGGTDHPTVQLPPVPS-------VGAPPAAAGGETPTRSVAGFR
MMAR_0876|M.marinum_M AY--QGEGGKDHPTIQLPPVPHQ---PPQLGEPPVAGGSDAPTRAFAGFR
MAV_4615|M.avium_104 E-----------QTTQIPPAAAAGDDKKDAAEPQPEPGGDAPTKAFAGFR
MSMEG_0975|M.smegmatis_MC2_155 -----MSASSEHPVPDSVDVPAP------EHPAAETPEAPSVFAPVPGFR
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK ----------------------------------------------MSFR
Mvan_0870|M.vanbaalenii_PYR-1 ------------------------------------------MDAPGSFR
MAB_3972c|M.abscessus_ATCC_199 AVPSLNSLGGSFAPLDFTPSGSQ------EAGDPTAVGAAGSSGGPGGFR
MLBr_00048|M.leprae_Br4923 MPMTPIDGSQRTPVTSPEPSLAEFEAQPPATPKPSLLPRPMSSPPEAPRP
MUL_0022|M.ulcerans_Agy99 DAAVRSGNSAIAAQVEMEPELEGMGTTLTAILFAGNRLGLVHIGDSRGYL
Mb0543|M.bovis_AF2122/97 TQR-------------------------------LDPTAYGAYYSGPDEG
Rv0530|M.tuberculosis_H37Rv TQR-------------------------------LDPTAYGAYYSGPDEG
MMAR_0876|M.marinum_M TERRSAARAEGAEAPDVAQWESGPDTGPVAGLPRVDPTAYGAYYNGPPEP
MAV_4615|M.avium_104 TERRVPEREPAPPTAPRPGGMPPWDSTPVTGIPRVDPTAYGAYYAGPDAP
MSMEG_0975|M.smegmatis_MC2_155 GQQRFSDPA-QAGVSTPLPAE-WTAPTPPHGIPVSAPQTAQTPPQNSHQP
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK AQQRFSDP------MAPVPAE-WTAPTPPEGVVP----------------
Mvan_0870|M.vanbaalenii_PYR-1 AQQRFSDP------MAPVPAE-WTAPTPPEGAPP----------------
MAB_3972c|M.abscessus_ATCC_199 ADNRFSDSGEQPAQPTPFTADRWASDTPPSGIPQQAQQPPVGGSRYYTPV
MLBr_00048|M.leprae_Br4923 SANQHSRHARRGHHHRDETQQANPASATEPMIAPRARTAELRQAPHAAAE
MUL_0022|M.ulcerans_Agy99 LRDGELTQITKDDTFVQTLVDEGRITAEEAHSHPQRSLIMRALTGHEVEP
Mb0543|M.bovis_AF2122/97 PASP-----------AERPPYRLEPVPHTPYPELATTTLLRPVKPPPSEG
Rv0530|M.tuberculosis_H37Rv PASP-----------AERPPYRLEPVPHTPYPELATTTLLRPVKPPPSEG
MMAR_0876|M.marinum_M PAEP-----------QYRP----ESVPQTPYPELSTSMLLRPVKSPPTEG
MAV_4615|M.avium_104 PTQI-----------QGPPP-RQEHLPHTPYPELSTGMLLRPVQPPPSEG
MSMEG_0975|M.smegmatis_MC2_155 MASGLPPLPPAPLTPPAAAAEQPPADFATPYEDLTTTALLGRRKSPPTAG
TH_0884|M.thermoresistible__bu -------------------------------VDLSTTALLGQRRPAPSRG
Mflv_0048|M.gilvum_PYR-GCK -----------------VVAAATPSTELVPYRELSTVALLGALPKAPSAG
Mvan_0870|M.vanbaalenii_PYR-1 -----------------VVTADP-----APYLDLSTVALLGNASRGPSAG
MAB_3972c|M.abscessus_ATCC_199 GGQ------------QTGVGGQIRPELPPSSRDLSTSALLRPHKPAPSAG
MLBr_00048|M.leprae_Br4923 PAPTQHLTRPDGLVSHRTALHDSTATSAIGVQTGRSTGAKKPSKVVAKRG
MUL_0022|M.ulcerans_Agy99 TLTIREARAG-----DRYLLCSDGLSDPVSDETIHEALQIPDVAESAYRL
.
Mb0543|M.bovis_AF2122/97 WRRLLYLLSGRLINAGEGPRAAHLNDLVAQVNRPLRGCYRIAVLSLKGGV
Rv0530|M.tuberculosis_H37Rv WRRLLYLLSGRLINAGEGPRAAHLNDLVAQVNRPLRGCYRIAVLSLKGGV
MMAR_0876|M.marinum_M WRRLVYVLSGQLINLGESPRATRYNNLVAQINRPMRGCYRIALVSLKGGV
MAV_4615|M.avium_104 WRLLLYKLSGGLINLGESPRAARYNNLVAQVNRPLRGSYRVAFLSLKGGV
MSMEG_0975|M.smegmatis_MC2_155 WRRWLYLASFKQVNVGESPKVTHRQSLVSQVSHPLQGCYRIAVLSLKGGV
TH_0884|M.thermoresistible__bu WRRWLYRATFRTVNLGESPKVARHNELLNRVRHPLQDCYRIAVLSLKGGV
Mflv_0048|M.gilvum_PYR-GCK WRKWVYRASGRLINPGESPKVIRHDDLLARVQQPLQGCYRVAMLSQKGGV
Mvan_0870|M.vanbaalenii_PYR-1 WRKWLYWGSGRLIDVGESPKVIRRNALVAQVQRPLRDCYRIAMLSQKGGV
MAB_3972c|M.abscessus_ATCC_199 WRKTVYRASFGTINLGEGTKKTEENDLIAQVNQPLQGCYKIALLSLKGGV
MLBr_00048|M.leprae_Br4923 WRHWVHTVTR--INLGLSPDERYELDLRTRVRRPPRGSYQIGILGLKGGA
MUL_0022|M.ulcerans_Agy99 IELALRGGGPDNVTVVVADVVDYEYGQTQPILAGAVSGDDDQLTLPNTAA
. : : . : . . : ..
Mb0543|M.bovis_AF2122/97 GKTTITATLGATFADLRGDRVVAVDANPDRGTLSQKVPLETPATVRHLLR
Rv0530|M.tuberculosis_H37Rv GKTTITATLGATFADLRGDRVVAVDANPDRGTLSQKVPLETPATVRHLLR
MMAR_0876|M.marinum_M GKTTITATLGSTFASVRGDRVVAVDANPDRGTLSQKVPLETPATVRHLIR
MAV_4615|M.avium_104 GKTTIAATLGATFASIRGDRVVAVDANPDRGTLSQKIPLETAATVRQLLH
MSMEG_0975|M.smegmatis_MC2_155 GKTTITATLGSTFASIRGDRVIAVDANPDRGTLSQKVPLETAATVRHLLR
TH_0884|M.thermoresistible__bu GKTTITATLGSTFGSARGDRVVAVDANPDRGTLSQKVPLQTRATVRDLLR
Mflv_0048|M.gilvum_PYR-GCK GKTTITATLGATFAGARGDRVIAVDANPDRGTLSQKVPVETPATVRHLLR
Mvan_0870|M.vanbaalenii_PYR-1 GKTTITATLGATFATTRGDRVIAVDANPDRGTLSQKVPLETPATVRHLLR
MAB_3972c|M.abscessus_ATCC_199 GKTTVTATLGATFASIRGDRVIAVDANPDRGTLSQKVPLETPATVRHLLR
MLBr_00048|M.leprae_Br4923 GKTTVTVTLGSMFARVRNDRILVVDADTSCGNLADRAGRFSEANIADLLA
MUL_0022|M.ulcerans_Agy99 GRASAITARKEAVKRVPPQVETVHRPRWSWRRMALVAELVVLLVVAGLFI
*::: .: . : . . . :: : *:
Mb0543|M.bovis_AF2122/97 DADGIERYSDVRGYTSKGPSGLEVLASDSDPASSDAFSADDYTRTLDILE
Rv0530|M.tuberculosis_H37Rv DADGIERYSDVRGYTSKGPSGLEVLASDSDPASSDAFSADDYTRTLDILE
MMAR_0876|M.marinum_M DAEGIERYSDVRGYTSQAKNGFEVLASDTDPAASEAFSADDYTRTLDILE
MAV_4615|M.avium_104 DAGTIERYSDVRRYTSKGPSGLEVLASETDPAVSEAFSADDYVRILDILE
MSMEG_0975|M.smegmatis_MC2_155 DAEGIERYSDVRAYTSQGPSRLEVLASESDPAVSEAFSSEDYLRTLEVLE
TH_0884|M.thermoresistible__bu DADRIQTYSDMRAYTSQSPSRLEVLASESDPAVSEAFSSDDYTRTLRVLE
Mflv_0048|M.gilvum_PYR-GCK DAEGVSAYSDVRRYTSQGPSRLEVLASESDPAVSEAFSATDYVRALNILE
Mvan_0870|M.vanbaalenii_PYR-1 DAEGIAAYSDVRQYTSQGPSRLEVLASESDPAVSEAFSAADYCRAVDVLE
MAB_3972c|M.abscessus_ATCC_199 DANSIQRYSDVRSYTSQGPSRLEVLASESDPAVSEAFSAEDYSRTLEILE
MLBr_00048|M.leprae_Br4923 DKD-VKSYNDIRTHTSVNAVNLEVLPAAEYSTAQHALSGEDWNFAAATVS
MUL_0022|M.ulcerans_Agy99 SRAVIRNNYYVAEFDGTVSIMRGIQGSFLGMSLHEPYLMGCLNARNELSQ
. : : . . : : : .. .
Mb0543|M.bovis_AF2122/97 RFYGLVLTDCGTGLLHSAMSAVLPRSDVLVVVSSGSIDGAR------SAA
Rv0530|M.tuberculosis_H37Rv RFYGLVLTDCGTGLLHSAMSAVLPRSDVLVVVSSGSIDGAR------SAA
MMAR_0876|M.marinum_M RFYGLVLTDCGTGLLHSAMSAILAKSDILIVVSSGSIDGAR------SAS
MAV_4615|M.avium_104 RFYGLVLTDCGPGLLHSVMKSVLDKADALVVVSSASIDGAR------SAS
MSMEG_0975|M.smegmatis_MC2_155 RFYSLVLTDCGTGLIHSAMSAVLSKADVLIVVSSGSVDGAR------SAA
TH_0884|M.thermoresistible__bu RFYSLVLTDCGTGLIHSAMSAVLANADVLIVISSGSVDGAR------SAA
Mflv_0048|M.gilvum_PYR-GCK RFYSMVLTDCGTGMLHSAMSAVIDKADVLVVISSGSADGAR------SAS
Mvan_0870|M.vanbaalenii_PYR-1 RFYSVVLTDCGTGMLHSAMSGVIDKADVLVVISSGSVDGAR------SAS
MAB_3972c|M.abscessus_ATCC_199 KFYSVVLTDCGTGLMHSAMSSVLEQADTLVVISSGSVDGAR------SAS
MLBr_00048|M.leprae_Br4923 KYYNVMLADCGVGLFDPVTRGVLSTASGVVIVTSTSVDAAR------QAA
MUL_0022|M.ulcerans_Agy99 ISYQQSGEHLDCNLMKLDDLRPPERAQVQAGLPAGSLDNAIGQLRELAAN
* . . .::. :. :.: * * * *
Mb0543|M.bovis_AF2122/97 ATLDWLQAHGHDDQVRNSIAVVNAVRPRA--------GKVDVGKVVEHFS
Rv0530|M.tuberculosis_H37Rv ATLDWLQAHGHDDQVRNSIAVVNAVRPRA--------GKVDVGKVVEHFS
MMAR_0876|M.marinum_M ATLDWLEAHGYEELVRNSIAVINAVRPRS--------SKVDMQKVIDHFA
MAV_4615|M.avium_104 ATLDWLDAHGHEDLVRNSIAVINGVRPRP--------GKVDMNKVIDHFS
MSMEG_0975|M.smegmatis_MC2_155 ATLDWLDAHGHQDLVRNSVAVLNAVRPRA--------GKVDLSKVVDHFS
TH_0884|M.thermoresistible__bu ATLDWLDAHGHQDMVRNSIAVINAVRPRS--------GKVDLQKVVDHFS
Mflv_0048|M.gilvum_PYR-GCK ATLDWLDAHGHDDMVRNSIAVINAVRPRGRRGTSRGTAKVDLDKIVDHFT
Mvan_0870|M.vanbaalenii_PYR-1 ATLDWLDAHGHGDMVGNSIAVINGVRRGARKGAGKGTAKVDLNKVVDHFA
MAB_3972c|M.abscessus_ATCC_199 ATLDWLDAHGHRELVRRSIAVINAVRPRS--------GKVDMQKVVDHFS
MLBr_00048|M.leprae_Br4923 IALDWLRHNGYQDLLSRACVVINHVMPKE--------PNIASKDLVQQFE
MUL_0022|M.ulcerans_Agy99 SLLPPCPAPRATSPPEPSAPSTASETPGQ--------PSVTSSPASTTTP
* . : .:
Mb0543|M.bovis_AF2122/97 RRCR--AVRVVPFDPHLEEGAEIALDRLRRETREALTELAAVVAAGFP--
Rv0530|M.tuberculosis_H37Rv RRCR--AVRVVPFDPHLEEGAEIALDRLRRETREALTELAAVVAAGFP--
MMAR_0876|M.marinum_M RRCR--AVRLVPFDPHLEEGAEIVLDRMKRETREALAELAAVVAEGFG--
MAV_4615|M.avium_104 RRCR--AVQLVPFDPHLEEGAEIDLDRLRRGTREALTELAAIVADGFP--
MSMEG_0975|M.smegmatis_MC2_155 RRCR--AVRLVPFDPHLEEGAEISLDRLKPKTREALLELAAVVAGDFGSD
TH_0884|M.thermoresistible__bu RRCR--AVKMVPFDPHLEEGAEIDLDQLKPQTRQALLELAAVVADGFP--
Mflv_0048|M.gilvum_PYR-GCK RRCR--AVCQVPFDAHLEEGAEISLDRLRPQTRESLLELAAAVADGFP--
Mvan_0870|M.vanbaalenii_PYR-1 RRCR--AVCQVPFDPHLEEGAEISLDRLRADTRESLLELAAAVADGFP--
MAB_3972c|M.abscessus_ATCC_199 RRCR--AVRLVPFDPHLEEGAEISLDRLRPQTRRALIELAAVVAQGFT--
MLBr_00048|M.leprae_Br4923 QQIQPGRVVVLPWDKHIAAGTEIRLDRLDPLYRRRILELAAALSDDFER-
MUL_0022|M.ulcerans_Agy99 TPSASTTPTTTSGSTAATSTPPAGTSPAAPTSPTPTSTTSSPNVTALPP-
. . . . :: :
Mb0543|M.bovis_AF2122/97 -----------GDPRRCKPSFT
Rv0530|M.tuberculosis_H37Rv -----------GDPRRCKPSFT
MMAR_0876|M.marinum_M -----------PDQRRSSPSFG
MAV_4615|M.avium_104 -----------G-AQRNPGVLG
MSMEG_0975|M.smegmatis_MC2_155 RTGALGGADSAGSRRIADPRV-
TH_0884|M.thermoresistible__bu -----------GAQQLQSPPF-
Mflv_0048|M.gilvum_PYR-GCK -----------GARNRSDPAD-
Mvan_0870|M.vanbaalenii_PYR-1 -----------GAR-RTDPVG-
MAB_3972c|M.abscessus_ATCC_199 -----------GTQRQQQTFQG
MLBr_00048|M.leprae_Br4923 -------------AGRH-----
MUL_0022|M.ulcerans_Agy99 ---------PPPQPGIDCRAVA