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SEHPTAGVGAPEEQTTQIPPAAAAGDDKKDAAEPQPEPGGDAPTKAFAGFRTERRVPEREPAPPTAPRPG GMPPWDSTPVTGIPRVDPTAYGAYYAGPDAPPTQIQGPPPRQEHLPHTPYPELSTGMLLRPVQPPPSEGW RLLLYKLSGGLINLGESPRAARYNNLVAQVNRPLRGSYRVAFLSLKGGVGKTTIAATLGATFASIRGDRV VAVDANPDRGTLSQKIPLETAATVRQLLHDAGTIERYSDVRRYTSKGPSGLEVLASETDPAVSEAFSADD YVRILDILERFYGLVLTDCGPGLLHSVMKSVLDKADALVVVSSASIDGARSASATLDWLDAHGHEDLVRN SIAVINGVRPRPGKVDMNKVIDHFSRRCRAVQLVPFDPHLEEGAEIDLDRLRRGTREALTELAAIVADGF PGAQRNPGVLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4615 | - | - | 100% (432) | hypothetical protein MAV_4615 |
| M. avium 104 | MAV_3857 | - | 5e-51 | 35.28% (377) | hypothetical protein MAV_3857 |
| M. avium 104 | MAV_0156 | - | 4e-43 | 34.10% (305) | hypothetical protein MAV_0156 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0543 | - | 1e-160 | 67.51% (434) | hypothetical protein Mb0543 |
| M. gilvum PYR-GCK | Mflv_0048 | - | 1e-123 | 65.90% (349) | hypothetical protein Mflv_0048 |
| M. tuberculosis H37Rv | Rv0530 | - | 1e-160 | 67.51% (434) | hypothetical protein Rv0530 |
| M. leprae Br4923 | MLBr_00798 | - | 3e-51 | 35.49% (355) | hypothetical protein MLBr_00798 |
| M. abscessus ATCC 19977 | MAB_3972c | - | 1e-133 | 65.71% (382) | hypothetical protein MAB_3972c |
| M. marinum M | MMAR_0876 | - | 1e-166 | 69.18% (438) | hypothetical protein MMAR_0876 |
| M. smegmatis MC2 155 | MSMEG_0975 | - | 1e-130 | 58.20% (445) | hypothetical protein MSMEG_0975 |
| M. thermoresistible (build 8) | TH_0884 | - | 1e-124 | 71.38% (304) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1004 | - | 2e-05 | 32.35% (102) | hypothetical protein MUL_1004 |
| M. vanbaalenii PYR-1 | Mvan_0870 | - | 1e-123 | 69.94% (336) | hypothetical protein Mvan_0870 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0543|M.bovis_AF2122/97 --------------------------------------------------
Rv0530|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0876|M.marinum_M --------------------------------------------------
MAV_4615|M.avium_104 --------------------------------------------------
MSMEG_0975|M.smegmatis_MC2_155 --------------------------------------------------
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0870|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3972c|M.abscessus_ATCC_199 ----------------------------MSDYPAHRAPDGPSPYAADEAQ
MLBr_00798|M.leprae_Br4923 MTTFRERRTMFDAAVASYQSGDKTSAGAAFARLTVENPDMSDSWLGRLAC
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
Mb0543|M.bovis_AF2122/97 -----------------------------------------MLVTEHPRT
Rv0530|M.tuberculosis_H37Rv -----------------------------------------MLVTEHPRT
MMAR_0876|M.marinum_M -----------------------------------------MDVSDHPSA
MAV_4615|M.avium_104 -------------------------------------------MSEHPTA
MSMEG_0975|M.smegmatis_MC2_155 --------------------------------------------------
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0870|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3972c|M.abscessus_ATCC_199 GGPTAPPWAAQEPAQPVMYGQSTPQQPHEMTQQFQAVPFQDPFAPQQDIA
MLBr_00798|M.leprae_Br4923 GDHNLDTLAGAHQHSEVLYSETRRVGLKDGDLRAEIAAPMYLTLTTWSRA
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
Mb0543|M.bovis_AF2122/97 GVGAPDS----GNGGTDHPTVQLPP-----------------------VP
Rv0530|M.tuberculosis_H37Rv GVGAPDS----GNGGTDHPTVQLPP-----------------------VP
MMAR_0876|M.marinum_M GVGASNAY--QGEGGKDHPTIQLPP-----------------------VP
MAV_4615|M.avium_104 GVGAPEE-----------QTTQIPP-----------------------AA
MSMEG_0975|M.smegmatis_MC2_155 -----------MSASSEHPVPDSVD-----------------------VP
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0870|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3972c|M.abscessus_ATCC_199 GLGHDPAVPSLNSLGGSFAPLDFTP-----------------------SG
MLBr_00798|M.leprae_Br4923 TIGLAYASALINAGRYDEASVALDDPVVTEDDDAALARQFVMATLFHQTR
MUL_1004|M.ulcerans_Agy99 --------------------------------------------------
Mb0543|M.bovis_AF2122/97 S-------VGAPPAAAGGETPTRSVAGFRTQR------------------
Rv0530|M.tuberculosis_H37Rv S-------VGAPPAAAGGETPTRSVAGFRTQR------------------
MMAR_0876|M.marinum_M HQ---PPQLGEPPVAGGSDAPTRAFAGFRTERRSAARAEGAEAPDVAQWE
MAV_4615|M.avium_104 AAGDDKKDAAEPQPEPGGDAPTKAFAGFRTERRVPEREPAPPTAPRPGGM
MSMEG_0975|M.smegmatis_MC2_155 AP------EHPAAETPEAPSVFAPVPGFRGQQRFSDPA-QAGVSTPLPAE
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK -------------------------MSFRAQQRFSDP------MAPVPAE
Mvan_0870|M.vanbaalenii_PYR-1 ---------------------MDAPGSFRAQQRFSDP------MAPVPAE
MAB_3972c|M.abscessus_ATCC_199 SQ------EAGDPTAVGAAGSSGGPGGFRADNRFSDSGEQPAQPTPFTAD
MLBr_00798|M.leprae_Br4923 SWSNVLKVAEVPPQNSNTDDRNELTDAVAALASTAASNLGQFQFALELTE
MUL_1004|M.ulcerans_Agy99 ---------MASTWSLSKGLAAVVVTSAAAFGLCPAAAADPAAPQPNPNP
Mb0543|M.bovis_AF2122/97 -------------LDPTAYGAYYSGPDEGPASP--------------AER
Rv0530|M.tuberculosis_H37Rv -------------LDPTAYGAYYSGPDEGPASP--------------AER
MMAR_0876|M.marinum_M SGPDTGPVAGLPRVDPTAYGAYYNGPPEPPAEP--------------QYR
MAV_4615|M.avium_104 PPWDSTPVTGIPRVDPTAYGAYYAGPDAPPTQI--------------QGP
MSMEG_0975|M.smegmatis_MC2_155 -WTAPTPPHGIPVSAPQTAQTPPQNSHQPMASGLPPLPP---APLTPPAA
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK -WTAPTPPEGVVP------------------------------------V
Mvan_0870|M.vanbaalenii_PYR-1 -WTAPTPPEGAPP------------------------------------V
MAB_3972c|M.abscessus_ATCC_199 RWASDTPPSGIPQQAQQPPVGGSRYYTPVGGQ---------------QTG
MLBr_00798|M.leprae_Br4923 RVSTTNPQVAADVALNRAWCLRELGDDNAARAALTAAPVNDIPTTHNTAE
MUL_1004|M.ulcerans_Agy99 QLPGLPALAQLSPIIQQAAGNPEQATQLLMAAA----------------Q
Mb0543|M.bovis_AF2122/97 PPYRLEPVPHTPYPELATTTLLRPVKPPPSEGWRRLLYLLSGRLINAGEG
Rv0530|M.tuberculosis_H37Rv PPYRLEPVPHTPYPELATTTLLRPVKPPPSEGWRRLLYLLSGRLINAGEG
MMAR_0876|M.marinum_M P----ESVPQTPYPELSTSMLLRPVKSPPTEGWRRLVYVLSGQLINLGES
MAV_4615|M.avium_104 PP-RQEHLPHTPYPELSTGMLLRPVQPPPSEGWRLLLYKLSGGLINLGES
MSMEG_0975|M.smegmatis_MC2_155 AAEQPPADFATPYEDLTTTALLGRRKSPPTAGWRRWLYLASFKQVNVGES
TH_0884|M.thermoresistible__bu -------------VDLSTTALLGQRRPAPSRGWRRWLYRATFRTVNLGES
Mflv_0048|M.gilvum_PYR-GCK VAAATPSTELVPYRELSTVALLGALPKAPSAGWRKWVYRASGRLINPGES
Mvan_0870|M.vanbaalenii_PYR-1 VTADP-----APYLDLSTVALLGNASRGPSAGWRKWLYWGSGRLIDVGES
MAB_3972c|M.abscessus_ATCC_199 VGGQIRPELPPSSRDLSTSALLRPHKPAPSAGWRKTVYRASFGTINLGEG
MLBr_00798|M.leprae_Br4923 PASRPQPTTFRHPYDDGRDLLVARRRPAAGDGWRKFVTKATLGRVNPEPS
MUL_1004|M.ulcerans_Agy99 AFAHNPAAPTESRNVASSVNQFVQEPVNPAPGSPPLGVPAPAAAPVEVAP
. . * .
Mb0543|M.bovis_AF2122/97 PRAAHLNDLVAQVNRPLRGCYRIAVLSLKGGVGKTTITATLGATFADLRG
Rv0530|M.tuberculosis_H37Rv PRAAHLNDLVAQVNRPLRGCYRIAVLSLKGGVGKTTITATLGATFADLRG
MMAR_0876|M.marinum_M PRATRYNNLVAQINRPMRGCYRIALVSLKGGVGKTTITATLGSTFASVRG
MAV_4615|M.avium_104 PRAARYNNLVAQVNRPLRGSYRVAFLSLKGGVGKTTIAATLGATFASIRG
MSMEG_0975|M.smegmatis_MC2_155 PKVTHRQSLVSQVSHPLQGCYRIAVLSLKGGVGKTTITATLGSTFASIRG
TH_0884|M.thermoresistible__bu PKVARHNELLNRVRHPLQDCYRIAVLSLKGGVGKTTITATLGSTFGSARG
Mflv_0048|M.gilvum_PYR-GCK PKVIRHDDLLARVQQPLQGCYRVAMLSQKGGVGKTTITATLGATFAGARG
Mvan_0870|M.vanbaalenii_PYR-1 PKVIRRNALVAQVQRPLRDCYRIAMLSQKGGVGKTTITATLGATFATTRG
MAB_3972c|M.abscessus_ATCC_199 TKKTEENDLIAQVNQPLQGCYKIALLSLKGGVGKTTVTATLGATFASIRG
MLBr_00798|M.leprae_Br4923 AKAEQTNELHRRICAPLADVHKVAFVSAKGGVGKTTITVALGNTMARLRG
MUL_1004|M.ulcerans_Agy99 PASAPVPHVPAPGAEPGTLAHLPAGIDPAHAAGPAPVAAPAGAPPASAPA
. : * : * :. ..* :.::.. * . . .
Mb0543|M.bovis_AF2122/97 DRVVAVDANPDRGTLSQKVP-LETPATVRHLLRDADGIERYSDVRGYTSK
Rv0530|M.tuberculosis_H37Rv DRVVAVDANPDRGTLSQKVP-LETPATVRHLLRDADGIERYSDVRGYTSK
MMAR_0876|M.marinum_M DRVVAVDANPDRGTLSQKVP-LETPATVRHLIRDAEGIERYSDVRGYTSQ
MAV_4615|M.avium_104 DRVVAVDANPDRGTLSQKIP-LETAATVRQLLHDAGTIERYSDVRRYTSK
MSMEG_0975|M.smegmatis_MC2_155 DRVIAVDANPDRGTLSQKVP-LETAATVRHLLRDAEGIERYSDVRAYTSQ
TH_0884|M.thermoresistible__bu DRVVAVDANPDRGTLSQKVP-LQTRATVRDLLRDADRIQTYSDMRAYTSQ
Mflv_0048|M.gilvum_PYR-GCK DRVIAVDANPDRGTLSQKVP-VETPATVRHLLRDAEGVSAYSDVRRYTSQ
Mvan_0870|M.vanbaalenii_PYR-1 DRVIAVDANPDRGTLSQKVP-LETPATVRHLLRDAEGIAAYSDVRQYTSQ
MAB_3972c|M.abscessus_ATCC_199 DRVIAVDANPDRGTLSQKVP-LETPATVRHLLRDANSIQRYSDVRSYTSQ
MLBr_00798|M.leprae_Br4923 DRVIAVDVDADLGDLSARFRERGGPQTNIEHFVSARNAKRYADVRVHTVM
MUL_1004|M.ulcerans_Agy99 PAAAAPASAPGTAPAPAAAP---GPAPAAPAPAPAAAAPAPAPAPAAPPA
. * .. . . . * : .
Mb0543|M.bovis_AF2122/97 GPSGLEVLASDSDPASSDAFSADDYTRTLDILERFYGLVLTDCGTGLLHS
Rv0530|M.tuberculosis_H37Rv GPSGLEVLASDSDPASSDAFSADDYTRTLDILERFYGLVLTDCGTGLLHS
MMAR_0876|M.marinum_M AKNGFEVLASDTDPAASEAFSADDYTRTLDILERFYGLVLTDCGTGLLHS
MAV_4615|M.avium_104 GPSGLEVLASETDPAVSEAFSADDYVRILDILERFYGLVLTDCGPGLLHS
MSMEG_0975|M.smegmatis_MC2_155 GPSRLEVLASESDPAVSEAFSSEDYLRTLEVLERFYSLVLTDCGTGLIHS
TH_0884|M.thermoresistible__bu SPSRLEVLASESDPAVSEAFSSDDYTRTLRVLERFYSLVLTDCGTGLIHS
Mflv_0048|M.gilvum_PYR-GCK GPSRLEVLASESDPAVSEAFSATDYVRALNILERFYSMVLTDCGTGMLHS
Mvan_0870|M.vanbaalenii_PYR-1 GPSRLEVLASESDPAVSEAFSAADYCRAVDVLERFYSVVLTDCGTGMLHS
MAB_3972c|M.abscessus_ATCC_199 GPSRLEVLASESDPAVSEAFSAEDYSRTLEILEKFYSVVLTDCGTGLMHS
MLBr_00798|M.leprae_Br4923 NNDRLEMLGAQNDPRSTYRLGPDDYETAMKILENHCNVILLDCGTPVNGP
MUL_1004|M.ulcerans_Agy99 APVAAPVAAPAPVPAPAPAAAPAPEAAAPAPAPAPAPAAAPGFGPDAPPT
: .. * : .. . *. .
Mb0543|M.bovis_AF2122/97 AMSAVLPRSDVLVVVSSGSIDGARSAAATLDWLQAHGHDDQVRNSIAVVN
Rv0530|M.tuberculosis_H37Rv AMSAVLPRSDVLVVVSSGSIDGARSAAATLDWLQAHGHDDQVRNSIAVVN
MMAR_0876|M.marinum_M AMSAILAKSDILIVVSSGSIDGARSASATLDWLEAHGYEELVRNSIAVIN
MAV_4615|M.avium_104 VMKSVLDKADALVVVSSASIDGARSASATLDWLDAHGHEDLVRNSIAVIN
MSMEG_0975|M.smegmatis_MC2_155 AMSAVLSKADVLIVVSSGSVDGARSAAATLDWLDAHGHQDLVRNSVAVLN
TH_0884|M.thermoresistible__bu AMSAVLANADVLIVISSGSVDGARSAAATLDWLDAHGHQDMVRNSIAVIN
Mflv_0048|M.gilvum_PYR-GCK AMSAVIDKADVLVVISSGSADGARSASATLDWLDAHGHDDMVRNSIAVIN
Mvan_0870|M.vanbaalenii_PYR-1 AMSGVIDKADVLVVISSGSVDGARSASATLDWLDAHGHGDMVGNSIAVIN
MAB_3972c|M.abscessus_ATCC_199 AMSSVLEQADTLVVISSGSVDGARSASATLDWLDAHGHRELVRRSIAVIN
MLBr_00798|M.leprae_Br4923 LFNKIVSTVTGLVVVASDDVRGVEGALATLDWLDAHGYARLLQHTVVVLN
MUL_1004|M.ulcerans_Agy99 QDFMYPSIGTNCLADGSNIIATALSVAGPATIPTPGPGPGQTAYVFTAVG
:. .* . .. .. . ...:.
Mb0543|M.bovis_AF2122/97 AVRPRA--------GKVDVGKVVEHFSR-RCRAVRVVPFDPHLEEGAEIA
Rv0530|M.tuberculosis_H37Rv AVRPRA--------GKVDVGKVVEHFSR-RCRAVRVVPFDPHLEEGAEIA
MMAR_0876|M.marinum_M AVRPRS--------SKVDMQKVIDHFAR-RCRAVRLVPFDPHLEEGAEIV
MAV_4615|M.avium_104 GVRPRP--------GKVDMNKVIDHFSR-RCRAVQLVPFDPHLEEGAEID
MSMEG_0975|M.smegmatis_MC2_155 AVRPRA--------GKVDLSKVVDHFSR-RCRAVRLVPFDPHLEEGAEIS
TH_0884|M.thermoresistible__bu AVRPRS--------GKVDLQKVVDHFSR-RCRAVKMVPFDPHLEEGAEID
Mflv_0048|M.gilvum_PYR-GCK AVRPRGRRGTSRGTAKVDLDKIVDHFTR-RCRAVCQVPFDAHLEEGAEIS
Mvan_0870|M.vanbaalenii_PYR-1 GVRRGARKGAGKGTAKVDLNKVVDHFAR-RCRAVCQVPFDPHLEEGAEIS
MAB_3972c|M.abscessus_ATCC_199 AVRPRS--------GKVDMQKVVDHFSR-RCRAVRLVPFDPHLEEGAEIS
MLBr_00798|M.leprae_Br4923 AIQKTK--------PFVDFGIVENQFRK-RVPDFYPMPYDPHLATGLAVE
MUL_1004|M.ulcerans_Agy99 TPGPAEV-------QRLPLNVTWVNLTTGKSGSVTLKPRSDINPEGPTTL
: . :: : . * . *
Mb0543|M.bovis_AF2122/97 LDRLRRETREALTELAAVVAAGFP-------------GDPRRCKPSFT--
Rv0530|M.tuberculosis_H37Rv LDRLRRETREALTELAAVVAAGFP-------------GDPRRCKPSFT--
MMAR_0876|M.marinum_M LDRMKRETREALAELAAVVAEGFG-------------PDQRRSSPSFG--
MAV_4615|M.avium_104 LDRLRRGTREALTELAAIVADGFP-------------GAQRN-PGVLG--
MSMEG_0975|M.smegmatis_MC2_155 LDRLKPKTREALLELAAVVAGDFGSDRTGALGGADSAGSRRIADPRV---
TH_0884|M.thermoresistible__bu LDQLKPQTRQALLELAAVVADGFP-------------GAQQLQSPPF---
Mflv_0048|M.gilvum_PYR-GCK LDRLRPQTRESLLELAAAVADGFP-------------GARNRSDPAD---
Mvan_0870|M.vanbaalenii_PYR-1 LDRLRADTRESLLELAAAVADGFP-------------GAR-RTDPVG---
MAB_3972c|M.abscessus_ATCC_199 LDRLRPQTRRALIELAAVVAQGFT-------------GTQRQQQTFQG--
MLBr_00798|M.leprae_Br4923 YTSLKRKTRKALKELVGGVAQYYP-----------VIRAQQRDEDGLGTW
MUL_1004|M.ulcerans_Agy99 TGIADTGSGSIMSTIFGQVTTKER---------------QCQFMPTIGST
: : : . *:
Mb0543|M.bovis_AF2122/97 ------------
Rv0530|M.tuberculosis_H37Rv ------------
MMAR_0876|M.marinum_M ------------
MAV_4615|M.avium_104 ------------
MSMEG_0975|M.smegmatis_MC2_155 ------------
TH_0884|M.thermoresistible__bu ------------
Mflv_0048|M.gilvum_PYR-GCK ------------
Mvan_0870|M.vanbaalenii_PYR-1 ------------
MAB_3972c|M.abscessus_ATCC_199 ------------
MLBr_00798|M.leprae_Br4923 IETIRQVEMTSR
MUL_1004|M.ulcerans_Agy99 VVP---------