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VLVTEHPRTGVGAPDSGNGGTDHPTVQLPPVPSVGAPPAAAGGETPTRSVAGFRTQRLDPTAYGAYYSGP DEGPASPAERPPYRLEPVPHTPYPELATTTLLRPVKPPPSEGWRRLLYLLSGRLINAGEGPRAAHLNDLV AQVNRPLRGCYRIAVLSLKGGVGKTTITATLGATFADLRGDRVVAVDANPDRGTLSQKVPLETPATVRHL LRDADGIERYSDVRGYTSKGPSGLEVLASDSDPASSDAFSADDYTRTLDILERFYGLVLTDCGTGLLHSA MSAVLPRSDVLVVVSSGSIDGARSAAATLDWLQAHGHDDQVRNSIAVVNAVRPRAGKVDVGKVVEHFSRR CRAVRVVPFDPHLEEGAEIALDRLRRETREALTELAAVVAAGFPGDPRRCKPSFT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0530 | - | - | 100% (405) | hypothetical protein Rv0530 |
| M. tuberculosis H37Rv | Rv3876 | - | 1e-51 | 35.41% (370) | hypothetical protein Rv3876 |
| M. tuberculosis H37Rv | Rv2787 | - | 3e-46 | 34.48% (290) | hypothetical protein Rv2787 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0543 | - | 0.0 | 100.00% (405) | hypothetical protein Mb0543 |
| M. gilvum PYR-GCK | Mflv_0048 | - | 1e-127 | 68.13% (342) | hypothetical protein Mflv_0048 |
| M. leprae Br4923 | MLBr_00048 | - | 3e-50 | 33.15% (371) | hypothetical protein MLBr_00048 |
| M. abscessus ATCC 19977 | MAB_3972c | - | 1e-133 | 60.58% (411) | hypothetical protein MAB_3972c |
| M. marinum M | MMAR_0876 | - | 1e-176 | 69.93% (439) | hypothetical protein MMAR_0876 |
| M. avium 104 | MAV_4615 | - | 1e-160 | 67.51% (434) | hypothetical protein MAV_4615 |
| M. smegmatis MC2 155 | MSMEG_0975 | - | 1e-140 | 62.91% (426) | hypothetical protein MSMEG_0975 |
| M. thermoresistible (build 8) | TH_0884 | - | 1e-128 | 72.90% (310) | conserved hypothetical protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0870 | - | 1e-124 | 68.84% (337) | hypothetical protein Mvan_0870 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0530|M.tuberculosis_H37Rv --------------------------------------------------
Mb0543|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0876|M.marinum_M --------------------------------------------------
MAV_4615|M.avium_104 --------------------------------------------------
MSMEG_0975|M.smegmatis_MC2_155 --------------------------------------------------
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0870|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3972c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00048|M.leprae_Br4923 MAADYDKLFRLDDGAYASPDQAAEQLFDDAPLYPPPIIPTCTTTPNGEVA
Rv0530|M.tuberculosis_H37Rv --------------------------------------------------
Mb0543|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0876|M.marinum_M --------------------------------------------------
MAV_4615|M.avium_104 --------------------------------------------------
MSMEG_0975|M.smegmatis_MC2_155 --------------------------------------------------
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0870|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3972c|M.abscessus_ATCC_199 ------MSDYPAHRAPDGPSPYAADEAQGGPTAPPWAAQEPAQPVMYGQS
MLBr_00048|M.leprae_Br4923 SPMPDWSEQLPPNPPAASKSPLPPMPIGSSVQPPPASSESPRAPMPVSAP
Rv0530|M.tuberculosis_H37Rv -------------------MLVTEHPRTGVGAPDS----GNGGTDHPTVQ
Mb0543|M.bovis_AF2122/97 -------------------MLVTEHPRTGVGAPDS----GNGGTDHPTVQ
MMAR_0876|M.marinum_M -------------------MDVSDHPSAGVGASNAY--QGEGGKDHPTIQ
MAV_4615|M.avium_104 ---------------------MSEHPTAGVGAPEE-----------QTTQ
MSMEG_0975|M.smegmatis_MC2_155 ---------------------------------------MSASSEHPVPD
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0870|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3972c|M.abscessus_ATCC_199 TPQQPHEMTQQFQAVPFQDPFAPQQDIAGLGHDPAVPSLNSLGGSFAPLD
MLBr_00048|M.leprae_Br4923 PRSPAASLMPISEPPQWPPAEAPEHQFAKAEPPSVPIPINEPSPAKPATP
Rv0530|M.tuberculosis_H37Rv LPPVPS-------VGAPP---AAAGGETPTRSVAGFRTQR----------
Mb0543|M.bovis_AF2122/97 LPPVPS-------VGAPP---AAAGGETPTRSVAGFRTQR----------
MMAR_0876|M.marinum_M LPPVPHQ---PPQLGEPP---VAGGSDAPTRAFAGFRTERRSAARAEGAE
MAV_4615|M.avium_104 IPPAAAAGDDKKDAAEPQ---PEPGGDAPTKAFAGFRTERRVPEREPAPP
MSMEG_0975|M.smegmatis_MC2_155 SVDVPAP------EHPAA---ETPEAPSVFAPVPGFRGQQRFSDPAQAGV
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK ---------------------------------MSFRAQQRFSD-----P
Mvan_0870|M.vanbaalenii_PYR-1 -----------------------------MDAPGSFRAQQRFSD-----P
MAB_3972c|M.abscessus_ATCC_199 FTPSGSQ------EAGDP---TAVGAAGSSGGPGGFRADNRFSDSGEQ-P
MLBr_00048|M.leprae_Br4923 MPMTPIDGSQRTPVTSPEPSLAEFEAQPPATPKPSLLPRPMSSPPEAPRP
Rv0530|M.tuberculosis_H37Rv ---------------------LDPTAYGAYYSGPDEGPASPAERPPY---
Mb0543|M.bovis_AF2122/97 ---------------------LDPTAYGAYYSGPDEGPASPAERPPY---
MMAR_0876|M.marinum_M APDVAQWESGPDTGPVAGLPRVDPTAYGAYYNGPPEPPAEPQYRP-----
MAV_4615|M.avium_104 TAPRPGGMPPWDSTPVTGIPRVDPTAYGAYYAGPDAPPTQIQGPPP----
MSMEG_0975|M.smegmatis_MC2_155 STPLP---AEWTA---------PTPPHGIPVSAPQTAQTPPQNSHQPMAS
TH_0884|M.thermoresistible__bu --------------------------------------------------
Mflv_0048|M.gilvum_PYR-GCK MAPVP---AEWTA---------PTPPEGVVPVVAAATPSTE---------
Mvan_0870|M.vanbaalenii_PYR-1 MAPVP---AEWTA---------PTPPEGAPPVVTADP-------------
MAB_3972c|M.abscessus_ATCC_199 AQPTPFTADRWAS---------DTPPSGIPQQAQQPPVGGSRYYTPVGGQ
MLBr_00048|M.leprae_Br4923 SANQHSRHARRGHHHRDETQQANPASATEPMIAPRARTAELRQAPHAAAE
Rv0530|M.tuberculosis_H37Rv ------------------RLEPVPHTPYPELATTTLLRPVKPP---PSEG
Mb0543|M.bovis_AF2122/97 ------------------RLEPVPHTPYPELATTTLLRPVKPP---PSEG
MMAR_0876|M.marinum_M --------------------ESVPQTPYPELSTSMLLRPVKSP---PTEG
MAV_4615|M.avium_104 ------------------RQEHLPHTPYPELSTGMLLRPVQPP---PSEG
MSMEG_0975|M.smegmatis_MC2_155 GLPPLPPAPLTPPAAAAEQPPADFATPYEDLTTTALLGRRKSP---PTAG
TH_0884|M.thermoresistible__bu ----------------------------VDLSTTALLGQRRPA---PSRG
Mflv_0048|M.gilvum_PYR-GCK ------------------------LVPYRELSTVALLGALPKA---PSAG
Mvan_0870|M.vanbaalenii_PYR-1 -------------------------APYLDLSTVALLGNASRG---PSAG
MAB_3972c|M.abscessus_ATCC_199 ------------QTGVGGQIRPELPPSSRDLSTSALLRPHKPA---PSAG
MLBr_00048|M.leprae_Br4923 PAPTQHLTRPDGLVSHRTALHDSTATSAIGVQTGRSTGAKKPSKVVAKRG
: * .. *
Rv0530|M.tuberculosis_H37Rv WRRLLYLLSGRLINAGEGPRAAHLNDLVAQVNRPLRGCYRIAVLSLKGGV
Mb0543|M.bovis_AF2122/97 WRRLLYLLSGRLINAGEGPRAAHLNDLVAQVNRPLRGCYRIAVLSLKGGV
MMAR_0876|M.marinum_M WRRLVYVLSGQLINLGESPRATRYNNLVAQINRPMRGCYRIALVSLKGGV
MAV_4615|M.avium_104 WRLLLYKLSGGLINLGESPRAARYNNLVAQVNRPLRGSYRVAFLSLKGGV
MSMEG_0975|M.smegmatis_MC2_155 WRRWLYLASFKQVNVGESPKVTHRQSLVSQVSHPLQGCYRIAVLSLKGGV
TH_0884|M.thermoresistible__bu WRRWLYRATFRTVNLGESPKVARHNELLNRVRHPLQDCYRIAVLSLKGGV
Mflv_0048|M.gilvum_PYR-GCK WRKWVYRASGRLINPGESPKVIRHDDLLARVQQPLQGCYRVAMLSQKGGV
Mvan_0870|M.vanbaalenii_PYR-1 WRKWLYWGSGRLIDVGESPKVIRRNALVAQVQRPLRDCYRIAMLSQKGGV
MAB_3972c|M.abscessus_ATCC_199 WRKTVYRASFGTINLGEGTKKTEENDLIAQVNQPLQGCYKIALLSLKGGV
MLBr_00048|M.leprae_Br4923 WRHWVHTVTR--INLGLSPDERYELDLRTRVRRPPRGSYQIGILGLKGGA
** :: : :: * .. * :: :* :..*::..:. ***.
Rv0530|M.tuberculosis_H37Rv GKTTITATLGATFADLRGDRVVAVDANPDRGTLSQKVPLETPATVRHLLR
Mb0543|M.bovis_AF2122/97 GKTTITATLGATFADLRGDRVVAVDANPDRGTLSQKVPLETPATVRHLLR
MMAR_0876|M.marinum_M GKTTITATLGSTFASVRGDRVVAVDANPDRGTLSQKVPLETPATVRHLIR
MAV_4615|M.avium_104 GKTTIAATLGATFASIRGDRVVAVDANPDRGTLSQKIPLETAATVRQLLH
MSMEG_0975|M.smegmatis_MC2_155 GKTTITATLGSTFASIRGDRVIAVDANPDRGTLSQKVPLETAATVRHLLR
TH_0884|M.thermoresistible__bu GKTTITATLGSTFGSARGDRVVAVDANPDRGTLSQKVPLQTRATVRDLLR
Mflv_0048|M.gilvum_PYR-GCK GKTTITATLGATFAGARGDRVIAVDANPDRGTLSQKVPVETPATVRHLLR
Mvan_0870|M.vanbaalenii_PYR-1 GKTTITATLGATFATTRGDRVIAVDANPDRGTLSQKVPLETPATVRHLLR
MAB_3972c|M.abscessus_ATCC_199 GKTTVTATLGATFASIRGDRVIAVDANPDRGTLSQKVPLETPATVRHLLR
MLBr_00048|M.leprae_Br4923 GKTTVTVTLGSMFARVRNDRILVVDADTSCGNLADRAGRFSEANIADLLA
****::.***: *. *.**::.***:.. *.*::: : *.: .*:
Rv0530|M.tuberculosis_H37Rv DADGIERYSDVRGYTSKGPSGLEVLASDSDPASSDAFSADDYTRTLDILE
Mb0543|M.bovis_AF2122/97 DADGIERYSDVRGYTSKGPSGLEVLASDSDPASSDAFSADDYTRTLDILE
MMAR_0876|M.marinum_M DAEGIERYSDVRGYTSQAKNGFEVLASDTDPAASEAFSADDYTRTLDILE
MAV_4615|M.avium_104 DAGTIERYSDVRRYTSKGPSGLEVLASETDPAVSEAFSADDYVRILDILE
MSMEG_0975|M.smegmatis_MC2_155 DAEGIERYSDVRAYTSQGPSRLEVLASESDPAVSEAFSSEDYLRTLEVLE
TH_0884|M.thermoresistible__bu DADRIQTYSDMRAYTSQSPSRLEVLASESDPAVSEAFSSDDYTRTLRVLE
Mflv_0048|M.gilvum_PYR-GCK DAEGVSAYSDVRRYTSQGPSRLEVLASESDPAVSEAFSATDYVRALNILE
Mvan_0870|M.vanbaalenii_PYR-1 DAEGIAAYSDVRQYTSQGPSRLEVLASESDPAVSEAFSAADYCRAVDVLE
MAB_3972c|M.abscessus_ATCC_199 DANSIQRYSDVRSYTSQGPSRLEVLASESDPAVSEAFSAEDYSRTLEILE
MLBr_00048|M.leprae_Br4923 DKD-VKSYNDIRTHTSVNAVNLEVLPAAEYSTAQHALSGEDWNFAAATVS
* : *.*:* :** :***.: .: ..*:*. *: :.
Rv0530|M.tuberculosis_H37Rv RFYGLVLTDCGTGLLHSAMSAVLPRSDVLVVVSSGSIDGARSAAATLDWL
Mb0543|M.bovis_AF2122/97 RFYGLVLTDCGTGLLHSAMSAVLPRSDVLVVVSSGSIDGARSAAATLDWL
MMAR_0876|M.marinum_M RFYGLVLTDCGTGLLHSAMSAILAKSDILIVVSSGSIDGARSASATLDWL
MAV_4615|M.avium_104 RFYGLVLTDCGPGLLHSVMKSVLDKADALVVVSSASIDGARSASATLDWL
MSMEG_0975|M.smegmatis_MC2_155 RFYSLVLTDCGTGLIHSAMSAVLSKADVLIVVSSGSVDGARSAAATLDWL
TH_0884|M.thermoresistible__bu RFYSLVLTDCGTGLIHSAMSAVLANADVLIVISSGSVDGARSAAATLDWL
Mflv_0048|M.gilvum_PYR-GCK RFYSMVLTDCGTGMLHSAMSAVIDKADVLVVISSGSADGARSASATLDWL
Mvan_0870|M.vanbaalenii_PYR-1 RFYSVVLTDCGTGMLHSAMSGVIDKADVLVVISSGSVDGARSASATLDWL
MAB_3972c|M.abscessus_ATCC_199 KFYSVVLTDCGTGLMHSAMSSVLEQADTLVVISSGSVDGARSASATLDWL
MLBr_00048|M.leprae_Br4923 KYYNVMLADCGVGLFDPVTRGVLSTASGVVIVTSTSVDAARQAAIALDWL
::*.::*:*** *::... .:: :. :::::* * *.**.*: :****
Rv0530|M.tuberculosis_H37Rv QAHGHDDQVRNSIAVVNAVRPR--------AGKVDVGKVVEHFSRRCR--
Mb0543|M.bovis_AF2122/97 QAHGHDDQVRNSIAVVNAVRPR--------AGKVDVGKVVEHFSRRCR--
MMAR_0876|M.marinum_M EAHGYEELVRNSIAVINAVRPR--------SSKVDMQKVIDHFARRCR--
MAV_4615|M.avium_104 DAHGHEDLVRNSIAVINGVRPR--------PGKVDMNKVIDHFSRRCR--
MSMEG_0975|M.smegmatis_MC2_155 DAHGHQDLVRNSVAVLNAVRPR--------AGKVDLSKVVDHFSRRCR--
TH_0884|M.thermoresistible__bu DAHGHQDMVRNSIAVINAVRPR--------SGKVDLQKVVDHFSRRCR--
Mflv_0048|M.gilvum_PYR-GCK DAHGHDDMVRNSIAVINAVRPRGRRGTSRGTAKVDLDKIVDHFTRRCR--
Mvan_0870|M.vanbaalenii_PYR-1 DAHGHGDMVGNSIAVINGVRRGARKGAGKGTAKVDLNKVVDHFARRCR--
MAB_3972c|M.abscessus_ATCC_199 DAHGHRELVRRSIAVINAVRPR--------SGKVDMQKVVDHFSRRCR--
MLBr_00048|M.leprae_Br4923 RHNGYQDLLSRACVVINHVMPK--------EPNIASKDLVQQFEQQIQPG
:*: : : .: .*:* * :: .::::* :: :
Rv0530|M.tuberculosis_H37Rv AVRVVPFDPHLEEGAEIALDRLRRETREALTELAAVVAAGFP--------
Mb0543|M.bovis_AF2122/97 AVRVVPFDPHLEEGAEIALDRLRRETREALTELAAVVAAGFP--------
MMAR_0876|M.marinum_M AVRLVPFDPHLEEGAEIVLDRMKRETREALAELAAVVAEGFG--------
MAV_4615|M.avium_104 AVQLVPFDPHLEEGAEIDLDRLRRGTREALTELAAIVADGFP--------
MSMEG_0975|M.smegmatis_MC2_155 AVRLVPFDPHLEEGAEISLDRLKPKTREALLELAAVVAGDFGSDRTGALG
TH_0884|M.thermoresistible__bu AVKMVPFDPHLEEGAEIDLDQLKPQTRQALLELAAVVADGFP--------
Mflv_0048|M.gilvum_PYR-GCK AVCQVPFDAHLEEGAEISLDRLRPQTRESLLELAAAVADGFP--------
Mvan_0870|M.vanbaalenii_PYR-1 AVCQVPFDPHLEEGAEISLDRLRADTRESLLELAAAVADGFP--------
MAB_3972c|M.abscessus_ATCC_199 AVRLVPFDPHLEEGAEISLDRLRPQTRRALIELAAVVAQGFT--------
MLBr_00048|M.leprae_Br4923 RVVVLPWDKHIAAGTEIRLDRLDPLYRRRILELAAALSDDFER-------
* :*:* *: *:** **:: *. : **** :: .*
Rv0530|M.tuberculosis_H37Rv -----GDPRRCKPSFT
Mb0543|M.bovis_AF2122/97 -----GDPRRCKPSFT
MMAR_0876|M.marinum_M -----PDQRRSSPSFG
MAV_4615|M.avium_104 -----GAQRN-PGVLG
MSMEG_0975|M.smegmatis_MC2_155 GADSAGSRRIADPRV-
TH_0884|M.thermoresistible__bu -----GAQQLQSPPF-
Mflv_0048|M.gilvum_PYR-GCK -----GARNRSDPAD-
Mvan_0870|M.vanbaalenii_PYR-1 -----GAR-RTDPVG-
MAB_3972c|M.abscessus_ATCC_199 -----GTQRQQQTFQG
MLBr_00048|M.leprae_Br4923 ------AGRH------