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M. thermoresistible (build 8) TH_3875 (-)

annotation: Cobyrinic acid a,c-diamide synthase
coordinates: 445100 - 445963
length: 288

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3875--100% (288)Cobyrinic acid a,c-diamide synthase
M. thermoresistible (build 8)TH_3319-8e-5044.05% (252) PUTATIVE cobyrinic Acid a,c-diamide synthase
M. thermoresistible (build 8)TH_2408parB4e-4040.00% (235) PROBABLE CHROMOSOME PARTITIONING PROTEIN PARA

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1735-1e-14386.36% (286) putative initiation inhibitor protein
M. gilvum PYR-GCKMflv_3498-1e-14290.22% (276) cobyrinic acid a,c-diamide synthase
M. tuberculosis H37RvRv1708-1e-14386.36% (286) putative initiation inhibitor protein
M. leprae Br4923MLBr_01367-1e-14185.02% (287) putative regulatory protein
M. abscessus ATCC 19977MAB_2367-1e-12781.32% (273) hypothetical protein MAB_2367
M. marinum MMMAR_2523-1e-13884.27% (286) Soj family ATPase
M. avium 104MAV_3068soj1e-14285.71% (287) SpoOJ regulator protein
M. smegmatis MC2 155MSMEG_3743soj1e-14490.94% (276) SpoOJ regulator protein
M. ulcerans Agy99MUL_3237-1e-13883.57% (286) Soj family ATPase
M. vanbaalenii PYR-1Mvan_3279-1e-14389.89% (277) cobyrinic acid a,c-diamide synthase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3498|M.gilvum_PYR-GCK          ---------------MTDPTGTPAPVDAPAAPAVAPDPEPTPGLTGRLPR
Mvan_3279|M.vanbaalenii_PYR-1       ---------------MTDPTG--GSLDAPAA---RSDAEPALGLTGRVPR
MSMEG_3743|M.smegmatis_MC2_155      -----------------------------------------MGLTGRPPR
TH_3875|M.thermoresistible__bu      ---------------MTD--------DAVTA--------EVVGLTGRPPR
MMAR_2523|M.marinum_M               MPAGLPAQADAAVRLSCDVHPDVLHNASRSGMNDHPDSGVSVGLTGRPPR
MUL_3237|M.ulcerans_Agy99           MPAGLPAQADAAVRLSCDVHPDVLHNASRSGMNDHPDSGVSVGLTGRPPR
MAV_3068|M.avium_104                -------------------------------MTERPDNGVELGLTGRPPR
Mb1735|M.bovis_AF2122/97            MPAGLPGQASVAVRLSCDVPPDARHHEPRPGMTDHPDTGNGIGLTGRPPR
Rv1708|M.tuberculosis_H37Rv         MPAGLPGQASVAVRLSCDVPPDARHHEPRPGMTDHPDTGNGIGLTGRPPR
MLBr_01367|M.leprae_Br4923          -------------------------------MIDHLDSVVEIGLTGRPPR
MAB_2367|M.abscessus_ATCC_1997      -------------------------MTDGSLDSDFPADDGDLDLTGRPPK
                                                                              .**** *:

Mflv_3498|M.gilvum_PYR-GCK          RIPEPAPRTSHGPAKVIAMCNQKGGVGKTTSTINLGASLAEYGRRVLLVD
Mvan_3279|M.vanbaalenii_PYR-1       QTPEPAPRTSHGPAKVIAMCNQKGGVGKTTSTINLGASLAEYGRRVLLVD
MSMEG_3743|M.smegmatis_MC2_155      EIPEPRPRETHGPAKVIAMCNQKGGVGKTTSTINLGASLAEYGRRVLLVD
TH_3875|M.thermoresistible__bu      PIPEPPPKSTHGPAKVIAMCNQKGGVGKTTSTINLGASLAEYGRRVLLVD
MMAR_2523|M.marinum_M               AIPDPKPLSSHGPAKVVAMCNQKGGVGKTTSTINLGAALAEYDRRVLLVD
MUL_3237|M.ulcerans_Agy99           AIPDPKPLSSHGPAKVVAMCNQKGGVGKTTSTINLGAALAEYDRRVLLVD
MAV_3068|M.avium_104                AIPEPQPRTSHGPAKVVAMCNQKGGVGKTTSTINLGAALAEYGRRVLLVD
Mb1735|M.bovis_AF2122/97            AIPDPTPRSSHGPAKVIAMCNQKGGVGKTTSTINLGAALGEYGRRVLLVD
Rv1708|M.tuberculosis_H37Rv         AIPDPAPRSSHGPAKVIAMCNQKGGVGKTTSTINLGAALGEYGRRVLLVD
MLBr_01367|M.leprae_Br4923          AIPEPRPRSSHGPAKVVAMCNQKGGVGKTTSTINLGAALTEFGRRVLLVD
MAB_2367|M.abscessus_ATCC_1997      DIPEPKPLTSHGPAKVIAMCNQKGGVGKTTSTINLGAALAGYGRRVLLVD
                                      *:* *  :******:********************:*  :.*******

Mflv_3498|M.gilvum_PYR-GCK          LDPQGALSAGLGVPHYELEHTVHNLLVEPRVSIDQVLIKTRVPGLDLVPS
Mvan_3279|M.vanbaalenii_PYR-1       LDPQGALSAGLGVPHYELEHTVHNLLVEPRVSIDQVLIKTRVPGLDLVPS
MSMEG_3743|M.smegmatis_MC2_155      LDPQGALSAGLGVPHYELDNTVHNLLVEPRVSIDDVLIKTRVSGMDLVPS
TH_3875|M.thermoresistible__bu      LDPQGALSAGLGVPHYDLDHTVYNLLVEPRVSIDEVLVSTRVRNLDLVPS
MMAR_2523|M.marinum_M               MDPQGALSAGLGVAHYELEKTIHNVLVEPRVSVDDVLIHTRVKNLDLVPS
MUL_3237|M.ulcerans_Agy99           MDPQGALSAGLGVAHYELEKTIHNVLVEPRVSVDDVLIHTRVKNLDLVPS
MAV_3068|M.avium_104                MDPQGALSAGLGVPHYELEKTIHNVLVEPRVSIDDVLLQTRVKHMDLVPS
Mb1735|M.bovis_AF2122/97            MDPQGALSAGLGVPHYELDKTIHNVLVEPRVSIDDVLIHSRVKNMDLVPS
Rv1708|M.tuberculosis_H37Rv         MDPQGALSAGLGVPHYELDKTIHNVLVEPRVSIDDVLIHSRVKNMDLVPS
MLBr_01367|M.leprae_Br4923          IDPQGALSAGLGVPHYELDRTIHNLMVEPLVSIDDVLIHTRVRYLDLVPS
MAB_2367|M.abscessus_ATCC_1997      LDPQGALSAGLGIAHHELETTVHNLLVEPRVSVDDVLMRTRVEGLDLIPS
                                    :***********:.*::*: *::*::*** **:*:**: :**  :**:**

Mflv_3498|M.gilvum_PYR-GCK          NIDLSAAEIQLVNEVGREQTLARALYPVLDRYDYVLIDCQPSLGLLTVNG
Mvan_3279|M.vanbaalenii_PYR-1       NIDLSAAEIQLVNEVGREQSLARALYPVLDRYDYVLIDCQPSLGLLTVNG
MSMEG_3743|M.smegmatis_MC2_155      NIDLSAAEIQLVNEVGREQSLARALYPVLDRYDYVLIDCQPSLGLLTING
TH_3875|M.thermoresistible__bu      NIDLSAAEIQLVTEVGREQALARALHPVLDRYDYVLIDCQPSLGLLTVNG
MMAR_2523|M.marinum_M               NIDLSAAEIQLVNEVGREQTLGRALYPVLDRYDYVLIDCQPSLGLLTVNG
MUL_3237|M.ulcerans_Agy99           NIDLSAAEIQLVNEVGREQTLGRALYPVLDRYDYVLVDCQPSLGLLTVNG
MAV_3068|M.avium_104                NIDLSAAEIQLVNEVGREQTLGRALHPVLDRYDYVLIDCQPSLGLLTVNG
Mb1735|M.bovis_AF2122/97            NIDLSAAEIQLVNEVGREQTLARALYPVLDRYDYVLIDCQPSLGLLTVNG
Rv1708|M.tuberculosis_H37Rv         NIDLSAAEIQLVNEVGREQTLARALYPVLDRYDYVLIDCQPSLGLLTVNG
MLBr_01367|M.leprae_Br4923          NIDLSAAEIQLVNEVGREQTLARALHPVLDRYDYVLIDCQPSLGLLTVNG
MAB_2367|M.abscessus_ATCC_1997      NIDLSAAEIQLVNEVGREHSLARALHPVLDRYDYVLIDCQPSLGLLTVNA
                                    ************.*****::*.***:**********:**********:*.

Mflv_3498|M.gilvum_PYR-GCK          LACSDGVVIPTECEFFSLRGLALLTDTVEKVHDRLNPKLEISGILITRYD
Mvan_3279|M.vanbaalenii_PYR-1       LACSDGVIIPTECEFFSLRGLALLTDTVEKVHDRLNPKLSISGILITRYD
MSMEG_3743|M.smegmatis_MC2_155      LACADGVVIPTECEYFSLRGLALLTDTVDKVHDRLNPKLSISGILVTRYD
TH_3875|M.thermoresistible__bu      LACSDGVIIPTECEYFSLRGLALLTDTVDKVRDRLNPKLEISGILVTRYD
MMAR_2523|M.marinum_M               LACADGVVIPTECEYFSLRGLALLTDTVEKVRDRLNPRLDISGILLTRYD
MUL_3237|M.ulcerans_Agy99           LACADGVVIPTECEYFSLRGLALLTDTVEKVRDRLNPRLDITGILLTRYD
MAV_3068|M.avium_104                LACSDGVVIPTECEYFSLRGLALLTDTVDKVRDRLNPKLEISGILLTRYD
Mb1735|M.bovis_AF2122/97            LACTDGVIIPTECEFFSLRGLALLTDTVDKVRDRLNPKLDISGILITRYD
Rv1708|M.tuberculosis_H37Rv         LACTDGVIIPTECEFFSLRGLALLTDTVDKVRDRLNPKLDISGILITRYD
MLBr_01367|M.leprae_Br4923          LACAEGVVIPTECEFFSLRGLALLTDTVDKVRDRLNPKLEISGILITRYD
MAB_2367|M.abscessus_ATCC_1997      LACSEGVVIPMECAFFSLRGLALLTDTVAKVRDRLNPKLAVSGIVITMFD
                                    ***::**:** ** :************* **:*****:* ::**::* :*

Mflv_3498|M.gilvum_PYR-GCK          NRTVNAREVMARVVERFGDLVFDTVITRTVRFPETSVAGEPITTWAPKSA
Mvan_3279|M.vanbaalenii_PYR-1       PRTVNSREVMARVVERFGDLVFDTVVTRTVRFPETSVAGEPITTWAPKSA
MSMEG_3743|M.smegmatis_MC2_155      PRTVNAREVMARVVERFGDLVFDTVITRTVRFPETSVAGEPITTWAPKSS
TH_3875|M.thermoresistible__bu      PRTVNSREVMARVVERFDDLVFDTVITRTVRFPETSVAGEPITTWAPKST
MMAR_2523|M.marinum_M               PRTVNSREVMARVVERFGDLVFDTVITRTVRFPETSVAGEPITTWAPKSA
MUL_3237|M.ulcerans_Agy99           PRTVNSREVMARVVERFGDLVFDTVITRTVRFPETSVAGEPITTWAPKSA
MAV_3068|M.avium_104                PRTVNAREVMARVVERFGDLVFDTVITRTVRFPETSVAGEPITTWAPRST
Mb1735|M.bovis_AF2122/97            PRTVNSREVMARVVERFGDLVFDTVITRTVRFPETSVAGEPITTWAPKSA
Rv1708|M.tuberculosis_H37Rv         PRTVNSREVMARVVERFGDLVFDTVITRTVRFPETSVAGEPITTWAPKSA
MLBr_01367|M.leprae_Br4923          PRTVNAREVMARVVERFGDLVFDTVITRTVRFPETSVAGEPITTWAPKSG
MAB_2367|M.abscessus_ATCC_1997      ARTLHAREVMARVIEVFGDQVFHTVITRTVRFPETSVAGEPITTWAPKSS
                                     **:::*******:* *.* **.**:*********************:* 

Mflv_3498|M.gilvum_PYR-GCK          GAEAYRALAREVIHRFGA
Mvan_3279|M.vanbaalenii_PYR-1       GAEAYRALAREVIHRFGA
MSMEG_3743|M.smegmatis_MC2_155      GAAAYRSLAREVIHRFGV
TH_3875|M.thermoresistible__bu      GAEAYRSLAREVIHRFGA
MMAR_2523|M.marinum_M               GALAYRVLAREFIDRFGV
MUL_3237|M.ulcerans_Agy99           GALAYRALAREFIDRFGV
MAV_3068|M.avium_104                GAIAYRALAREFIDRFGA
Mb1735|M.bovis_AF2122/97            GALAYRALARELIDRFGM
Rv1708|M.tuberculosis_H37Rv         GALAYRALARELIDRFGM
MLBr_01367|M.leprae_Br4923          GARAYRALACEFIDRFGA
MAB_2367|M.abscessus_ATCC_1997      GAQAYISLAREVIDRFET
                                    ** **  ** *.*.**