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TIRLGLQIPNFSYGTGVEKLFPSVIAQAREAEAAGYDSLFVMDHFYQLPMLGTPDQPMLEAYTALGALAT ATERLQLGALVTGNTYRSPTLLAKIITTLDVVSAGRAILGIGAGWFELEHRQLGFEFGTFSDRFNRLEEA LQILEPMVKGERPTFFGDWYTTESAMAEPRYRDRIPILIGGGGEKKTFAIAARFADHLNIVAAVDELPRK MRALAARCDEAGRDRSTLQTSLLLTVMIDETLSPDAIPAEMSGRVVVGSPAQIADQIQAKVLDAGVDGLI INLAPHGYLPGVITTAAEALRPLLGV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1855c | - | - | 100% (307) | POSSIBLE OXIDOREDUCTASE |
| M. tuberculosis H37Rv | Rv0044c | - | 4e-34 | 39.41% (203) | oxidoreductase |
| M. tuberculosis H37Rv | Rv0791c | - | 4e-30 | 30.23% (301) | hypothetical protein Rv0791c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1886c | - | 1e-173 | 100.00% (307) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3347 | - | 1e-115 | 64.50% (307) | luciferase family protein |
| M. leprae Br4923 | MLBr_00269 | - | 4e-13 | 25.37% (268) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2431c | - | 1e-115 | 61.42% (324) | luciferase-like oxidoreductase |
| M. marinum M | MMAR_2729 | - | 1e-146 | 82.30% (305) | oxidoreductase |
| M. avium 104 | MAV_2865 | - | 1e-127 | 71.90% (306) | hypothetical protein MAV_2865 |
| M. smegmatis MC2 155 | MSMEG_3620 | - | 1e-117 | 66.45% (307) | hypothetical protein MSMEG_3620 |
| M. thermoresistible (build 8) | TH_1174 | - | 1e-123 | 67.86% (308) | POSSIBLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_3024 | - | 1e-145 | 81.64% (305) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_3077 | - | 1e-112 | 63.52% (307) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1855c|M.tuberculosis_H37Rv -MTIRLGLQIPNFSYGTGVEKLFPSVIAQAREAEAAGYDSLFVMDHFYQL
Mb1886c|M.bovis_AF2122/97 -MTIRLGLQIPNFSYGTGVEKLFPSVIAQAREAEAAGYDSLFVMDHFYQL
MMAR_2729|M.marinum_M -MAIRLGFQIPSFSYGTGVDKLFPSVIAQAREAEAAGFDSLFLMDHFYQL
MUL_3024|M.ulcerans_Agy99 -MAIRLGFQIPSFSYGTGVDKLFPSVIAQAREAEAAGFDSLFLMDHFYQL
Mflv_3347|M.gilvum_PYR-GCK -MSIRLGLQINNFSYGTGVSDLFPTVVAQAKEADTSGFDSVFLMDHFYQL
Mvan_3077|M.vanbaalenii_PYR-1 -MTIRLGLQINNFSYGTPVPDLFPTVVAQAQEADASGFDSVFVMDHFYQL
MSMEG_3620|M.smegmatis_MC2_155 -MTIRLALQIPNFSYGTGVEELFPTVIAQAKEAEDAGFDTVFVMDHFYQL
MAV_2865|M.avium_104 -MAIRLGLQIPNFSYGTGAEQLFPTVIAQAREAESAGFDSVFVMDHFYQL
TH_1174|M.thermoresistible__bu -VSIRLGLQIPNFSYGTGVADLFPTVIAQAREADEAGYDAVFVMDHFYQL
MAB_2431c|M.abscessus_ATCC_199 -MTIRLGYQIPNFSYGTGVAELFPTVVKQVREAEASGFDTVFVMDHFYQL
MLBr_00269|M.leprae_Br4923 MAELRLGYKASAEQFAP------RELVELGVAAEAHGMDSATVSDHFQPW
:**. : .:.. :: *: * *: : ***
Rv1855c|M.tuberculosis_H37Rv PMLGTPDQPMLEAYTALGALATATERLQLGALVTGNTYR-SPTLLAKIIT
Mb1886c|M.bovis_AF2122/97 PMLGTPDQPMLEAYTALGALATATERLQLGALVTGNTYR-SPTLLAKIIT
MMAR_2729|M.marinum_M PMLGTPDQPMLEAYTALGALATATERLQLGTLVTGNTYR-NPALLAKIIT
MUL_3024|M.ulcerans_Agy99 PMLGTPDQPMLEAYTALGALATATERLQLGTLVTGNTYR-NPALLAKIIT
Mflv_3347|M.gilvum_PYR-GCK PGIGTPDQPMLEAYTALGALAAATDSVQLGTLVTGNTYR-NPTLLAKNIT
Mvan_3077|M.vanbaalenii_PYR-1 PGLGTPDQPMLEAYTALGALAAVTQNVQLGTLVTGNTYR-NPTLLAKNIT
MSMEG_3620|M.smegmatis_MC2_155 PGIGEPEEPMLEAYTALGGLATATERVQLGTLVTGNTYR-NPTLLAKAIT
MAV_2865|M.avium_104 PMLGSPDQPMLEAYTALGALATATERVQLGTLVTGNTYR-NPTLLAKIIT
TH_1174|M.thermoresistible__bu PMLGDPDEPMLEAYTALGGLATSTERVQLGTLVTGNTYR-NPTLLAKAVT
MAB_2431c|M.abscessus_ATCC_199 PMIGTPDQPMLEAYTALGALASATSTIQLSTLVTGNTYR-NPALLAKAVT
MLBr_00269|M.leprae_Br4923 RHQGGHASFSLSWMTAVG---ERTNRILLGTSVLTPTFRYNPAVIGQAFA
* . *. **:* *. : *.: * *:* .*:::.: .:
Rv1855c|M.tuberculosis_H37Rv TLDVVSAGRAILGIGAGWFELEHRQLGFE--FGTFSDRFNRLEEALQILE
Mb1886c|M.bovis_AF2122/97 TLDVVSAGRAILGIGAGWFELEHRQLGFE--FGTFSDRFNRLEEALQILE
MMAR_2729|M.marinum_M TLDVVSAGRAVLGIGAGWFELEHRQLGYE--FGTFTDRFNRLEEALQILD
MUL_3024|M.ulcerans_Agy99 TLDVVSAGRAVLGIGAGWFELEHRQLGYE--FGTFTDRFNRLEEALQILD
Mflv_3347|M.gilvum_PYR-GCK TLDVISAGRAILGIGTGWFELEHDQLGYE--FGTFTDRFNKLGEALQIIL
Mvan_3077|M.vanbaalenii_PYR-1 TLDVISQGRAVLGIGTGWFELEHDQLGYE--FGTFTERFDKLDEALQIIV
MSMEG_3620|M.smegmatis_MC2_155 TLDVVSRGRAVLGLGTGWFELEHDQLGYE--FGTFTQRFEKLDEALQIIL
MAV_2865|M.avium_104 TLDVVSQGRAILGIGTGWFQLEHDQLGFE--FGTFTDRFNRLDEALEIIL
TH_1174|M.thermoresistible__bu TLDVMSQGRAVLGIGTGWFELEHQQLGYE--FGTFTDRFNRLYEALEIIV
MAB_2431c|M.abscessus_ATCC_199 TLDVVSGGRAILGIGAGWFELEHQQLGFE--FGTFTDRFERLTEALEIIP
MLBr_00269|M.leprae_Br4923 TMGCLYPNRVFLGVGTG-EALNEVATGYQGAWPEFKERFARLRESVRLMR
*:. : .*..**:*:* *:. *:: : *.:** :* *::.::
Rv1855c|M.tuberculosis_H37Rv PMVKGERPTFFGDWYTTESAMAEPRYRDRIPILIGGGGEKKTFAIAARFA
Mb1886c|M.bovis_AF2122/97 PMVKGERPTFFGDWYTTESAMAEPRYRDRIPILIGGGGEKKTFAIAARFA
MMAR_2729|M.marinum_M PMIKGERPTFSGSWYQAESAMAEPRYRDRIPILIGGGGEKKTFRIAAHWA
MUL_3024|M.ulcerans_Agy99 PIIKGERPTFSGSWYQAESAMAEPRYRDRIPILIGGGGEKKTFRIAAHWA
Mflv_3347|M.gilvum_PYR-GCK PMIKGETPTFSGEYYSVKDAMANPRFREHIPLMIGGSGEKKTIPLAARHF
Mvan_3077|M.vanbaalenii_PYR-1 PMLKGERPTFTGRHYRVQEAMANPRFREHIPLMIGGSGEKKTIPLAARHF
MSMEG_3620|M.smegmatis_MC2_155 PMLKGERPTFSGKYYRTENALANPRFRDHIPLMIGGSGEKKTIPMAVRHF
MAV_2865|M.avium_104 PMIRGERATFEGKWYRASDAFANPRYRDRIPLMIGGSGEKKTIPLAARHF
TH_1174|M.thermoresistible__bu PMIEGKRPTFEGRYYRVESAAAEPRFRDRIPLMIGGSGEKKTIPLAARRF
MAB_2431c|M.abscessus_ATCC_199 PMLRGERPTFEGKYYRTESALNEPRLRPNIPIMIGGSGEKKTFGLAVKYA
MLBr_00269|M.leprae_Br4923 ELWRGDRVDFDGDYYQLKGASIYDVPEGGVPIYIAAGGPEVAKYAGRAGE
: .*. * * * . * . :*: *...* : : .
Rv1855c|M.tuberculosis_H37Rv DHLNIVAAVDELP--RKMRALAARCDEAGRDRSTLQTSLLLTVMIDET--
Mb1886c|M.bovis_AF2122/97 DHLNIVAAVDELP--RKMRALAARCDEAGRDRSTLQTSLLLTVMIDET--
MMAR_2729|M.marinum_M DHLNIVAALDELP--RKMDAVAARCEEAGRDPSTLETSVMLTVVVDEK--
MUL_3024|M.ulcerans_Agy99 DHLNIVAALDELP--RKMDAVAARCEEAGRDPSTLETSVMLTVVVDAK--
Mflv_3347|M.gilvum_PYR-GCK DHLNVIAGFDELA--RKIDVVTQACEKIDRDPSTLETSMLIGALTGDG--
Mvan_3077|M.vanbaalenii_PYR-1 DHLNVIAGFDELA--RKIEVIEQRCADIDRDPATLETSVLVGALVGDD--
MSMEG_3620|M.smegmatis_MC2_155 DHLNVIAGFDELA--RKLDVIKKNCDEIDRDPATLETSVLLSAIIDEN--
MAV_2865|M.avium_104 DHLNVIAGFDELP--RKLDAVRRACEQVGRDPATLETSTLTTVMIDDN--
TH_1174|M.thermoresistible__bu DHLNLIAGFDELP--GKVAAVKRSCEEIGRDPDTLETSTLVSVMVDDN--
MAB_2431c|M.abscessus_ATCC_199 DHLNLLSSLDEIP--HKLTVLRQRCEEAGRDPSTLETSAFFSVFIDDDSA
MLBr_00269|M.leprae_Br4923 GFVCTSGKGEELYTEKLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDPE
..: . :*: : .: . .** ::. .
Rv1855c|M.tuberculosis_H37Rv -----------------------------LSPDAIPAEMS----GRVVVG
Mb1886c|M.bovis_AF2122/97 -----------------------------LSPDAIPAEMS----GRVVVG
MMAR_2729|M.marinum_M -----------------------------AKVERLPAETS----RRMVTG
MUL_3024|M.ulcerans_Agy99 -----------------------------AKVERLPAETS----RRMVTG
Mflv_3347|M.gilvum_PYR-GCK -----------------------------VSPDMIPEDFR----QRMVAG
Mvan_3077|M.vanbaalenii_PYR-1 -----------------------------VSPDQIPDEFK----QRMVAG
MSMEG_3620|M.smegmatis_MC2_155 -----------------------------ASLDAIPEPFR----QRSVVG
MAV_2865|M.avium_104 -----------------------------ASLDQIPAEMT----QRMVVG
TH_1174|M.thermoresistible__bu -----------------------------ITDDMLPEKAR----GRLLVG
MAB_2431c|M.abscessus_ATCC_199 TAWK---------------LAASQLSQNGIDLDTLPDEARAQVLGRTLVG
MLBr_00269|M.leprae_Br4923 QALSNIRFWAPLSLAAEQKHSIDDPIEMEKVADALPIEQVAK--RWIVVS
: :* :..
Rv1855c|M.tuberculosis_H37Rv SPAQIADQIQAKVLDAGVDGLIINLAPH--GYLPGVITTAAEALRPLLGV
Mb1886c|M.bovis_AF2122/97 SPAQIADQIQAKVLDAGVDGLIINLAPH--GYLPGVITTAAEALRPLLGV
MMAR_2729|M.marinum_M SPAQIADQVQTKVLDTGIDGVIMNLSAH--GHSPGLITTVAEALRPLLTG
MUL_3024|M.ulcerans_Agy99 SPAQIADQVQTKVLDTGIDGVIMNLSAH--GHSPGLITTVAEALRPLLTG
Mflv_3347|M.gilvum_PYR-GCK TPEQIAEQVQSKVLDAGVDGVILFVPTQTVGYQPGQITALGEALKPLVAG
Mvan_3077|M.vanbaalenii_PYR-1 TVDQVAEQIKTKVLDAGIDGVILYVPTQIVGYQPGQITALGEALAPLVTA
MSMEG_3620|M.smegmatis_MC2_155 TPEQIAEQVKTKVLDLGIDGVAINIPTWQLGYRPGDITAIGEALKPLISG
MAV_2865|M.avium_104 NPDSVADQIKTKVIDAGIDSVIINLP----FYTPGIVQAAGEALRPLVGA
TH_1174|M.thermoresistible__bu SAERIAEQLQTKVLDAGVDGVIVNMATKVQGYRPGLITALGEALRPRVGA
MAB_2431c|M.abscessus_ATCC_199 NPEEIAEQVQTRVLDQGIDSVTLNAPAT--GHLPGVVELIGNTLRPLFKN
MLBr_00269|M.leprae_Br4923 DPDEAVARVG-QYVTWGLNHLVFHAPGH---NQRRFLELFEKDLAPRLRR
. :: : : *:: : . . : : * * .
Rv1855c|M.tuberculosis_H37Rv --
Mb1886c|M.bovis_AF2122/97 --
MMAR_2729|M.marinum_M --
MUL_3024|M.ulcerans_Agy99 --
Mflv_3347|M.gilvum_PYR-GCK --
Mvan_3077|M.vanbaalenii_PYR-1 --
MSMEG_3620|M.smegmatis_MC2_155 --
MAV_2865|M.avium_104 --
TH_1174|M.thermoresistible__bu --
MAB_2431c|M.abscessus_ATCC_199 --
MLBr_00269|M.leprae_Br4923 LG