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M. thermoresistible (build 8) TH_0491 (-)

annotation: regulatory protein GntR, HTH
coordinates: 1060614 - 1061132
length: 173

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0491--100% (173)regulatory protein GntR, HTH
M. thermoresistible (build 8)TH_2873-2e-2558.82% (102) PUTATIVE regulatory protein GntR, HTH
M. thermoresistible (build 8)TH_4408-1e-2354.90% (102) PUTATIVE regulatory protein GntR, HTH

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3086c-7e-0932.71% (107) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_2114-3e-4985.96% (114) GntR domain-containing protein
M. tuberculosis H37RvRv3060c-7e-0932.71% (107) GntR family transcriptional regulator
M. leprae Br4923MLBr_01188-2e-0633.33% (72) hypothetical protein MLBr_01188
M. abscessus ATCC 19977MAB_4644c-7e-0844.44% (63) GntR family transcriptional regulator
M. marinum MMMAR_3975-5e-2044.55% (110) FadR family transcriptional regulator
M. avium 104MAV_2542-3e-4378.90% (109) regulatory protein GntR, HTH
M. smegmatis MC2 155MSMEG_5201-3e-5087.72% (114) regulatory protein GntR, HTH
M. ulcerans Agy99MUL_3832-3e-2044.55% (110) FadR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_4590-2e-5086.96% (115) GntR domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2114|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
TH_0491|M.thermoresistible__bu      --------------------------------------------------
MAV_2542|M.avium_104                --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASLGSESALQQRFCVSR
Rv3060c|M.tuberculosis_H37Rv        MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASLGSESALQQRFCVSR
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_2114|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
TH_0491|M.thermoresistible__bu      --------------------------------------------------
MAV_2542|M.avium_104                --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           SVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPATRAVVIYLEYLGTT
Rv3060c|M.tuberculosis_H37Rv        SVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPATRAVVIYLEYLGTT
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_2114|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
TH_0491|M.thermoresistible__bu      --------------------------------------------------
MAV_2542|M.avium_104                --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           IGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLRAEERWRPGLPPPPE
Rv3060c|M.tuberculosis_H37Rv        IGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLRAEERWRPGLPPPPE
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_2114|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_4590|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
TH_0491|M.thermoresistible__bu      --------------------------------------------------
MAV_2542|M.avium_104                --------------------------------------------------
MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           QFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQSAGEAVEAAGQVHN
Rv3060c|M.tuberculosis_H37Rv        QFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQSAGEAVEAAGQVHN
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mflv_2114|M.gilvum_PYR-GCK          ---------------------------MARSTPLAPMIGPDAVASRTAVR
Mvan_4590|M.vanbaalenii_PYR-1       ---------------------------MTRNTPLAPMIGPDAVASRAAVR
MSMEG_5201|M.smegmatis_MC2_155      ---------------------------MAGSTPLAPMIGPDAITPRAAVR
TH_0491|M.thermoresistible__bu      ------------------------------------MIGPGSTPG-ASVR
MAV_2542|M.avium_104                ---------------------------MPKREPLAPMATS---QNNGAVR
MMAR_3975|M.marinum_M               -----------------------------------MTALGIGPDPRRRLS
MUL_3832|M.ulcerans_Agy99           -----------------------------------MTALGIGPDPRRRLS
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           EHSDIVAAVTAGDSAWAKTLSERHVEAVAGWLQQHQRGNDAAVRNGGRAR
Rv3060c|M.tuberculosis_H37Rv        EHSDIVAAVTAGDSAWAKTLSERHVEAVAGWLQQHQRGNDAAVRNGGRAR
MAB_4644c|M.abscessus_ATCC_199      --------------------------------------------MHPRLS
                                                                                      

Mflv_2114|M.gilvum_PYR-GCK          SP-------------KTAELVAGTLRRMVVEGQLKDGDFLPNEAELMAHF
Mvan_4590|M.vanbaalenii_PYR-1       SP-------------KTAELVAGTLRRMVVEGQLKDGDFLPNEAELMAHF
MSMEG_5201|M.smegmatis_MC2_155      SP-------------KTAELVAGTLRRMVVEGQLKDGDFLPNEAELMSHF
TH_0491|M.thermoresistible__bu      SP-------------KTAELVAGTLRRMVVDGTLKDGDFLPNEAELMAHF
MAV_2542|M.avium_104                SP-------------KTAEIVADTLRRMIVEGQLKDGDFLPYEAELMDHF
MMAR_3975|M.marinum_M               AP-------------RIAEIVADELRRQIIDGELADGDLLPRQEVLVEQF
MUL_3832|M.ulcerans_Agy99           AP-------------RIAEIVADELRRQIIDGELADGDLLPRQEVLVEQF
MLBr_01188|M.leprae_Br4923          ---------------------------------------MPRQEALVEPL
Mb3086c|M.bovis_AF2122/97           EPRRAQQLILGAPRGKLAEVLAATIGDDIAASGWQVGSVFGTETALLERY
Rv3060c|M.tuberculosis_H37Rv        EPRRAQQLILGAPRGKLAEVLAATIGDDIAASGWQVGSVFGTETALLERY
MAB_4644c|M.abscessus_ATCC_199      SQ-------------SLAEQVANILAAQIGDGRWSTGAKLPGEVALCEEF
                                                                           :  :  *    

Mflv_2114|M.gilvum_PYR-GCK          GVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIVARPAGLLLEL
Mvan_4590|M.vanbaalenii_PYR-1       GVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIVARPAGLLLEL
MSMEG_5201|M.smegmatis_MC2_155      GVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIVARPVGLLLEL
TH_0491|M.thermoresistible__bu      GVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIVARPAALLLEL
MAV_2542|M.avium_104                QVSRPSLREAVRVLESDRLVEVRRGSRTGARVRVPGPEIVARPAGFLLEM
MMAR_3975|M.marinum_M               NVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKTSAAYMLGLLLQS
MUL_3832|M.ulcerans_Agy99           NVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKASAAYMLGLLLQS
MLBr_01188|M.leprae_Br4923          NVSLLSFREALQIMDTERLISLRRGNRGSVVVHTPTRTSAAYMLGLLLQS
Mb3086c|M.bovis_AF2122/97           QVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQPQASIDTIALYLQY
Rv3060c|M.tuberculosis_H37Rv        QVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQPQASIDTIALYLQY
MAB_4644c|M.abscessus_ATCC_199      GVSRATVREAIRDLKTKGLVSTRQG--AGVFVTSDRP-----LGQWDRVL
                                     **   .***:: :. . :   *:*   .  *                  

Mflv_2114|M.gilvum_PYR-GCK          SGATIADLLTAKSAIEPMAARLLAESGSAAAFDELEQLLEELVADSHQSP
Mvan_4590|M.vanbaalenii_PYR-1       SGATIADLLTAKSGIEPMAARLLAESGSPEAFDELERMLEELAADSHKSS
MSMEG_5201|M.smegmatis_MC2_155      SGADIADLLVARSAIEPMAARLLAENGTEEQFAELDRMLEEHIPSDWQSD
TH_0491|M.thermoresistible__bu      SGATVADVMVARSGTGSAGPPCAKRCG------------------CWSPS
MAV_2542|M.avium_104                AGTTLADVMTARMGIEPYAARLLAEDGTAAAHRELRELIEEIP-AAWETG
MMAR_3975|M.marinum_M               ESVAVSDLGAALQELEPACAALAAQRPDRADTLVPELKRVNEAMSEHLDD
MUL_3832|M.ulcerans_Agy99           ESVAVSDLGAALQELEPACAALAAQRPDRADTLVPELKRVNEAMSEHLDD
MLBr_01188|M.leprae_Br4923          KSIALADLGAALQELEPACAALAAQ-------------------------
Mb3086c|M.bovis_AF2122/97           RKPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASFLDTLGRPRLDNPTDD
Rv3060c|M.tuberculosis_H37Rv        RKPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASFLDTLGRPRLDNPTDD
MAB_4644c|M.abscessus_ATCC_199      AAAEIDAVVEIRRLLEVQAAGLAAERRNRSDVAAIRRALVARAKAESAGD
                                           :                .                         

Mflv_2114|M.gilvum_PYR-GCK          --RLAEATGAFHLRVVQLSGNATLSIVAGMLHEITVRHTAFVFN----ER
Mvan_4590|M.vanbaalenii_PYR-1       --RLAEATGLFHLRVVQLSGNATLSIVAGMLHEITVRHTAFVFN----ER
MSMEG_5201|M.smegmatis_MC2_155      --RLAETTGDFHRRVVELSGNATLGIIAGMLHEITVRHHQFLFR----EH
TH_0491|M.thermoresistible__bu      --GWSRCG----------AG-----------------------------R
MAV_2542|M.avium_104                --KLGAASTALHRRLVELSGNATLTVIVGMLHEIFERHMTAAFLS---VQ
MMAR_3975|M.marinum_M               GAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWTSHEQQWADESAARG
MUL_3832|M.ulcerans_Agy99           GAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWTSHEQQWADESAARG
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           VRAAAVEEFRFHVGLARAAGNTMLDLFLLILVELFRRHLSST------EQ
Rv3060c|M.tuberculosis_H37Rv        VRAAAVEEFRFHVGLARAAGNTMLDLFLLILVELFRRHLSST------EQ
MAB_4644c|M.abscessus_ATCC_199      DIEYVDADLEFHRAVVAAVHNPLLDELFDSFSVRMREAMLALLAG-----
                                                                                      

Mflv_2114|M.gilvum_PYR-GCK          RPVSKADYETLLRSYRRLLQFLRSRDADGAEAHWRRHLDKTRELLLAGLE
Mvan_4590|M.vanbaalenii_PYR-1       RPVSKADYDTLLRSYRKLMQFLRAGDAVGAEAHWRKHLDTTRELLLTGLE
MSMEG_5201|M.smegmatis_MC2_155      RPVSKSDYDKLMRSYRKLMQIMRSGDGDAAEAHWRTHLDTARALMLQGLE
TH_0491|M.thermoresistible__bu      APARGSG----CRARRSWLARPR--------CCWNCPARRSPT-------
MAV_2542|M.avium_104                NVVPKAQYNKLMRSYTRLADLVAARDGAEAEAHWRRHMENASAELLKGHE
MMAR_3975|M.marinum_M               TYPSLTKRRAVLNTHIKLTETIAEGDVDRARRIAGRHLADTQTYVLSGRA
MUL_3832|M.ulcerans_Agy99           TYPSLAKRRAVLNAHIKLTETIAEGDVDRARRIAGRHLADTQTYVLSGRA
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           ALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAASWWL----
Rv3060c|M.tuberculosis_H37Rv        ALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAASWWL----
MAB_4644c|M.abscessus_ATCC_199      ----SAERPHDQEHHQWLFDAIVDGSTRRAVELATDQLQHVRMR------
                                                                                      

Mflv_2114|M.gilvum_PYR-GCK          SVPVRDVMG------------
Mvan_4590|M.vanbaalenii_PYR-1       SVPVRDVMG------------
MSMEG_5201|M.smegmatis_MC2_155      SVKVRDVMG------------
TH_0491|M.thermoresistible__bu      ---------------------
MAV_2542|M.avium_104                KTKVRDIMH------------
MMAR_3975|M.marinum_M               EQRIYALSPQALSRPRDMRRP
MUL_3832|M.ulcerans_Agy99           EQRIYALSPQALSRPRDMRRP
MLBr_01188|M.leprae_Br4923          ---------------------
Mb3086c|M.bovis_AF2122/97           ---------------------
Rv3060c|M.tuberculosis_H37Rv        ---------------------
MAB_4644c|M.abscessus_ATCC_199      ---------------------