For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. thermoresistible (build 8) TH_0441 (-)

annotation: phosphotransferase enzyme family protein, putative
coordinates: 966798 - 967886
length: 363

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0441--100% (363)phosphotransferase enzyme family protein, putative
M. thermoresistible (build 8)TH_3623-1e-5537.93% (348) PUTATIVE putative aminoglycoside phosphotransferase
M. thermoresistible (build 8)TH_3597-5e-4133.97% (365) PUTATIVE putative aminoglycoside phosphotransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3102-1e-12963.10% (355) aminoglycoside phosphotransferase
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4589c-9e-0842.86% (70) putative phosphotransferase
M. marinum MMMAR_4035-1e-13363.28% (354) hypothetical protein MMAR_4035
M. avium 104MAV_1568-1e-13664.69% (354) phosphotransferase enzyme family protein, putative
M. smegmatis MC2 155MSMEG_3876-1e-14167.04% (361) phosphotransferase enzyme family protein, putative
M. ulcerans Agy99MUL_1045-3e-1424.34% (341) hypothetical protein MUL_1045
M. vanbaalenii PYR-1Mvan_3433-1e-13264.97% (354) aminoglycoside phosphotransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3102|M.gilvum_PYR-GCK          ---------------------------MTIPRTPADLTPTWLESVLDAG-
Mvan_3433|M.vanbaalenii_PYR-1       ---------------------------MTIPRSPQDITPTWLASVLGTE-
TH_0441|M.thermoresistible__bu      -----------------------MSTVLSIPSGPAEVTPEWLSTVLSADG
MSMEG_3876|M.smegmatis_MC2_155      -----------------------MTAAVSIPGRPVDVTPSWLSGVLGTE-
MMAR_4035|M.marinum_M               --------------------------MVSIPRHPTDVTPQWLAAVLGERG
MAV_1568|M.avium_104                --------------------------MLSIPRYPGDVTPQWLSAALSGRG
MUL_1045|M.ulcerans_Agy99           MIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDPPALSEIMGRR-
MAB_4589c|M.abscessus_ATCC_199      --------------MHKDVSSDSDGPTGDAASLDADAIPTSLSEYLNREL
                                                                  .    :  *  *   :.   

Mflv_3102|M.gilvum_PYR-GCK          ----VDDVTVTAIGTGQTGATYRVSATYDNPTAADLPATFAVKLPAQDDA
Mvan_3433|M.vanbaalenii_PYR-1       ----VSGVEVAAIGTGQTGATYRVTATY--PESPSPPATFAVKLPAQDDA
TH_0441|M.thermoresistible__bu      TPVRVRSVDVVPIGTGQTGATYRLTVGY-ETERADLPPTFAIKLPAQDES
MSMEG_3876|M.smegmatis_MC2_155      ----VATAATEPIGTGQTGATYRVTVTY-AGD-SALPTTFAIKLPSQDDT
MMAR_4035|M.marinum_M               TPVGVSGVDVVPIGTGQTGATYRLTVIY-DPDPAGLPDTFVIKLPAQDDT
MAV_1568|M.avium_104                APVEVAEVDVAAIGTGQTGATYRVTARY-ATDPGDLPQTFVIKLPAQDDT
MUL_1045|M.ulcerans_Agy99           ----VSSVSVLDDSSGTTSRARLALSGN------DVPESVFVKMAAATAA
MAB_4589c|M.abscessus_ATCC_199      G----EQVSVRRLSAGHSNLTYVVTGSS-GTQWILRRPPFGRLQAGAHDV
                                           . .   .:* :. :                 ..    ..    

Mflv_3102|M.gilvum_PYR-GCK          VRERVALG--YLSEVDFYSTITADVAVPVPGCYHSEISSDGTDFVLVLAD
Mvan_3433|M.vanbaalenii_PYR-1       VRERVALG--YLSEVDFYAAINRDVAIPVPDCFHTEISTDGKDFVLVLAD
TH_0441|M.thermoresistible__bu      VRERVALG--YRAEHAFYTRVAAHMAIPVPHCYHCEIGGDGAEFAMLMAD
MSMEG_3876|M.smegmatis_MC2_155      VRDRVAIG--YRSEHAFYTSLAGQVRIPVPHCYHCEIAGEGADFVLVLAD
MMAR_4035|M.marinum_M               VRDRVVVG--YRSECAFYSSVADRVRVPTPRCFYCEITEDAMDFALLLED
MAV_1568|M.avium_104                VRDRVVIG--YRSECAFYSSVADRVQVPTPRCFYSEITEDAMDFALLLAD
MUL_1045|M.ulcerans_Agy99           TRFIGELGRLAETEVSFYRDLSPELAPDAPTAYGCAFDPLTGRFVLVLED
MAB_4589c|M.abscessus_ATCC_199      MREYRVLD----------ALSTAQVRVPRVTLASTDAEIFGAPFYLMERQ
                                     *    :.                :                  * ::  :

Mflv_3102|M.gilvum_PYR-GCK          MAPAEQG-----DQIAGCTAAEAALAVEAIAGLHGPSWGDRRYFDLPSIV
Mvan_3433|M.vanbaalenii_PYR-1       MAPAEQG-----DQIAGCTPAEAALAVEALAGLHGPSWNERRYFDLPSIV
TH_0441|M.thermoresistible__bu      MAPAVQG-----DQIVGCSPAEARLAVTALAGLHGPSWCDPQWADVPGIA
MSMEG_3876|M.smegmatis_MC2_155      MAPAEQG-----DQIAGCSPAEAALAVRALADLHGPTWCDPQWANFPGIA
MMAR_4035|M.marinum_M               QAPAVQG-----DQLTGCGEREARLAVVALAGLHGPSWCDPVWLDQPGIA
MAV_1568|M.avium_104                QAPAVQG-----DQLLGCGETEARLAVTALAGLHAPSWCDPVWLDFPGIA
MUL_1045|M.ulcerans_Agy99           LAAPAEGTCDFSDTLHPFDNDQAALVVELLARLHATYWVRLNHGGVRPFG
MAB_4589c|M.abscessus_ATCC_199      DGEVIRD----VSPEWFVGSARRELVLDLAVALAEIHNADP-----TRLV
                                     .   ..     .        .  *.:   . *               : 

Mflv_3102|M.gilvum_PYR-GCK          MPKPGDEAAASGMGEVAVMAANMTLEKLGGSVDDEDRDTLLTSMSLVTPW
Mvan_3433|M.vanbaalenii_PYR-1       MPKPGDEAAAAGMGEVAKMAADITLDKLGGSVSDEDRDTLVTSMSLVTPW
TH_0441|M.thermoresistible__bu      MPKP-DDAAAEGLGEIAEMAADITIDKLGPRMRPEDRETTLTAMSMVTAW
MSMEG_3876|M.smegmatis_MC2_155      MPKP-EPDSAKGFGDIAKMAADITLDKLGDRLSIGDRETLSASMSVVTPW
MMAR_4035|M.marinum_M               FPFP-DEPFANGLGEVARMSAEITLDKLGDRLSAADRETFTETMNLVTPW
MAV_1568|M.avium_104                FGRP-DEAGAGGMGEVAKMSADITLERLGDRMSAEDRETFAAAMGVIAPW
MUL_1045|M.ulcerans_Agy99           WRYAASRDPSVPLVPTMLRASWRRLGGHAAALLPG-RDFVFEHYRAITGL
MAB_4589c|M.abscessus_ATCC_199      EAKLGRESGYLARQLKTWGGQWESIKELPTGRDLQDHTTITAWLTEN---
                                                       .    :           :             

Mflv_3102|M.gilvum_PYR-GCK          LMAVPDRFSLMHGDYRLDNLLYDPE--RTRVTVVDWQTVGIGLPTRDLAY
Mvan_3433|M.vanbaalenii_PYR-1       LLAVPDRFSLMHGDYRLDNLLYDPD--RTRVTVVDWQTMGIGLPSRDLAY
TH_0441|M.thermoresistible__bu      LRTEKSRFALMHGDYRLDNMLFDPD--RTRVTVVDWQTMGAGLPARDLSY
MSMEG_3876|M.smegmatis_MC2_155      LLAEPDRFAVLHGDYRLDNMLFDPD--RTRVTVVDWQTLGSGLPARDLSY
MMAR_4035|M.marinum_M               LLAERDRFALLHGDYRLDNLLFDPD--LRRVAVVDWQTLGIGLPARDLGY
MAV_1568|M.avium_104                LLSEYDRFALLHGDYRLDNLLFDPD--RTRVSVVDWQTLGVGLPARDLAY
MUL_1045|M.ulcerans_Agy99           IDAPP--HTVLHGDAHPGNWYFRSSGGPLAAGLLDWQAIRLGHPARDLAY
MAB_4589c|M.abscessus_ATCC_199      -YPGDRPAAVVHGDYKLDNVLVDPAT-ARITAVLDWEMATVGDPLADLGY
                                      .     :::*** : .*    .      . ::**:    * *  **.*

Mflv_3102|M.gilvum_PYR-GCK          FTATSLLPD--------DRAAVERDLVQRYHAALLAHGVSGYDVETCWQD
Mvan_3433|M.vanbaalenii_PYR-1       FTATSLLPE--------TRAEVERDLVEHYHAALLGHGVSGYDVETCWHD
TH_0441|M.thermoresistible__bu      FLGTSLLPE--------VRSEVERDLVEVYHRALRSHGVADYDSETCWRD
MSMEG_3876|M.smegmatis_MC2_155      FTATSLDPA--------DRAAAERDLVGEYHRTLLAHGVTGYDRETCWRD
MMAR_4035|M.marinum_M               FTATSLNSQ--------LRSDIEESLVDDYHRKLLSYGVTGYDWETCWRD
MAV_1568|M.avium_104                FTATSLDSP--------LRAAIEEELVADYHRALVAGGVNGYDRETCWRD
MUL_1045|M.ulcerans_Agy99           TLITGMTTT--------DRRVTERELLDVYRRALAAAGGPELDREEPWLR
MAB_4589c|M.abscessus_ATCC_199      LLYMTPEPGGEVAMSELTGSVTAQEGCPSHTEIAQAYREARSGDQSYWTP
                                           .               ..    :     .      . :  *  

Mflv_3102|M.gilvum_PYR-GCK          YRLGVFQAP----LITALGFAFAASTERGDE-MILTMLHRGCRAIRELGA
Mvan_3433|M.vanbaalenii_PYR-1       YRLGVLQAP----LITVLGTAFASSTERGDE-MMLTMLHRGCRAIRELAS
TH_0441|M.thermoresistible__bu      YRLGMLQVP----LLTVLGFAFAASTERGDD-MMLTMLERGGRAIRELDS
MSMEG_3876|M.smegmatis_MC2_155      YRLGMLQAP----LITVLGCAFASSTDRGDD-MMVVMAQRGCQAIRELGT
MMAR_4035|M.marinum_M               YRLGMPHTV----LISALGFAFATATERGDE-MVLTMLGRGCQAIRDLET
MAV_1568|M.avium_104                YRLGVLQAP----LISALGFAFAAATERGDD-MVLTMLGRGCRAIRELGT
MUL_1045|M.ulcerans_Agy99           YRQAAACAY----VATTIAAGLGG--MQAAD-IALTGLDLTVAALHDLQT
MAB_4589c|M.abscessus_ATCC_199      EDLVYYQVLGGWKLATLLEVSYQRHLAGTTDDPFFAELDEGVPRLLSVAR
                                           .     : : :  .         :   ..        : .:  

Mflv_3102|M.gilvum_PYR-GCK          IDLVRSYQASTQPSSPTTA-------------------------------
Mvan_3433|M.vanbaalenii_PYR-1       IDLVRSYQVS----SPTTA-------------------------------
TH_0441|M.thermoresistible__bu      LELVNPAAS-----------------------------------------
MSMEG_3876|M.smegmatis_MC2_155      LDLIDAAS------------------------------------------
MMAR_4035|M.marinum_M               LELIG---------------------------------------------
MAV_1568|M.avium_104                LELIG---------------------------------------------
MUL_1045|M.ulcerans_Agy99           VAALRAADLGGTSWAWRPGMARSARIRPGASARRCPMVWSTSSHILGVSR
MAB_4589c|M.abscessus_ATCC_199      SLIPAAG-------------------------------------------
                                                                                      

Mflv_3102|M.gilvum_PYR-GCK          -------
Mvan_3433|M.vanbaalenii_PYR-1       -------
TH_0441|M.thermoresistible__bu      -------
MSMEG_3876|M.smegmatis_MC2_155      -------
MMAR_4035|M.marinum_M               -------
MAV_1568|M.avium_104                -------
MUL_1045|M.ulcerans_Agy99           HFAMGAW
MAB_4589c|M.abscessus_ATCC_199      -------