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VLSIPRYPGDVTPQWLSAALSGRGAPVEVAEVDVAAIGTGQTGATYRVTARYATDPGDLPQTFVIKLPAQ DDTVRDRVVIGYRSECAFYSSVADRVQVPTPRCFYSEITEDAMDFALLLADQAPAVQGDQLLGCGETEAR LAVTALAGLHAPSWCDPVWLDFPGIAFGRPDEAGAGGMGEVAKMSADITLERLGDRMSAEDRETFAAAMG VIAPWLLSEYDRFALLHGDYRLDNLLFDPDRTRVSVVDWQTLGVGLPARDLAYFTATSLDSPLRAAIEEE LVADYHRALVAGGVNGYDRETCWRDYRLGVLQAPLISALGFAFAAATERGDDMVLTMLGRGCRAIRELGT LELIG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1568 | - | - | 100% (355) | phosphotransferase enzyme family protein, putative |
| M. avium 104 | MAV_2467 | - | 2e-37 | 32.68% (355) | phosphotransferase enzyme family protein |
| M. avium 104 | MAV_5276 | - | 7e-22 | 29.23% (366) | phosphotransferase enzyme family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3193 | - | 1e-07 | 26.81% (276) | hypothetical protein Mb3193 |
| M. gilvum PYR-GCK | Mflv_3102 | - | 1e-125 | 61.69% (355) | aminoglycoside phosphotransferase |
| M. tuberculosis H37Rv | Rv3168 | - | 5e-08 | 26.81% (276) | hypothetical protein Rv3168 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4589c | - | 3e-07 | 48.21% (56) | putative phosphotransferase |
| M. marinum M | MMAR_4035 | - | 1e-161 | 77.75% (355) | hypothetical protein MMAR_4035 |
| M. smegmatis MC2 155 | MSMEG_3876 | - | 1e-135 | 66.01% (353) | phosphotransferase enzyme family protein, putative |
| M. thermoresistible (build 8) | TH_0441 | - | 1e-136 | 64.69% (354) | phosphotransferase enzyme family protein, putative |
| M. ulcerans Agy99 | MUL_1045 | - | 1e-17 | 27.40% (365) | hypothetical protein MUL_1045 |
| M. vanbaalenii PYR-1 | Mvan_3433 | - | 1e-126 | 61.86% (354) | aminoglycoside phosphotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3193|M.bovis_AF2122/97 --MANEPAIGAIDRLQRSSRDVTTL-PAVISRWLSSVLPGGAAP--EVTV
Rv3168|M.tuberculosis_H37Rv --MANEPAIGAIDRLQRSSRDVTTL-PAVISRWLSSVLPGGAAP--EVTV
MAV_1568|M.avium_104 -----------MLSIPRYPGDVT-------PQWLSAALSGRGAPVEVAEV
MMAR_4035|M.marinum_M -----------MVSIPRHPTDVT-------PQWLAAVLGERGTPVGVSGV
MSMEG_3876|M.smegmatis_MC2_155 --------MTAAVSIPGRPVDVT-------PSWLSGVLGTE-----VATA
TH_0441|M.thermoresistible__bu --------MSTVLSIPSGPAEVT-------PEWLSTVLSADGTPVRVRSV
Mflv_3102|M.gilvum_PYR-GCK ------------MTIPRTPADLT-------PTWLESVLDAG-----VDDV
Mvan_3433|M.vanbaalenii_PYR-1 ------------MTIPRSPQDIT-------PTWLASVLGTE-----VSGV
MUL_1045|M.ulcerans_Agy99 MIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDPPALSEIMGRRV
MAB_4589c|M.abscessus_ATCC_199 ------MHKDVSSDSDGPTGDAASLDADAIPTSLSEYLNRELG----EQV
. : . . : .
Mb3193|M.bovis_AF2122/97 ESGVDSTGMSSETIILTARR-QQDGRSIQQKLVARVAPAAEDVPVFPTYR
Rv3168|M.tuberculosis_H37Rv ESGVDSTGMSSETIILTARW-QQDGRSIQQKLVARVAPAAEDVPVFPTYR
MAV_1568|M.avium_104 DVAAIGTGQTGATYRVTARY-ATDPGDLPQTFVIKLPAQDDTVRDRVVIG
MMAR_4035|M.marinum_M DVVPIGTGQTGATYRLTVIY-DPDPAGLPDTFVIKLPAQDDTVRDRVVVG
MSMEG_3876|M.smegmatis_MC2_155 ATEPIGTGQTGATYRVTVTY-AGD-SALPTTFAIKLPSQDDTVRDRVAIG
TH_0441|M.thermoresistible__bu DVVPIGTGQTGATYRLTVGY-ETERADLPPTFAIKLPAQDESVRERVALG
Mflv_3102|M.gilvum_PYR-GCK TVTAIGTGQTGATYRVSATYDNPTAADLPATFAVKLPAQDDAVRERVALG
Mvan_3433|M.vanbaalenii_PYR-1 EVAAIGTGQTGATYRVTATY--PESPSPPATFAVKLPAQDDAVRERVALG
MUL_1045|M.ulcerans_Agy99 SSVSVLDDSSGTTSRARLAL---SGNDVPESVFVKMAAATAATRFIGELG
MAB_4589c|M.abscessus_ATCC_199 SVRRLSAGHSNLTYVVTGSS-GTQWILRRPPFGRLQAGAHDVMREYRVLD
. :. * . .
Mb3193|M.bovis_AF2122/97 --LDHQFEVIRLVGELTDVPVPRVRWIETTGDVLGTPFFLMDYVEGVVP-
Rv3168|M.tuberculosis_H37Rv --LDHQFEVIRLVGELTDVPVPRVRWIETTGDVLGTPFFLMDYVEGVVP-
MAV_1568|M.avium_104 --YRSECAFYSSVADRVQVPTPRCFYSEITEDAMDFALLLADQAPAVQG-
MMAR_4035|M.marinum_M --YRSECAFYSSVADRVRVPTPRCFYCEITEDAMDFALLLEDQAPAVQG-
MSMEG_3876|M.smegmatis_MC2_155 --YRSEHAFYTSLAGQVRIPVPHCYHCEIAGEGADFVLVLADMAPAEQG-
TH_0441|M.thermoresistible__bu --YRAEHAFYTRVAAHMAIPVPHCYHCEIGGDGAEFAMLMADMAPAVQG-
Mflv_3102|M.gilvum_PYR-GCK --YLSEVDFYSTITADVAVPVPGCYHSEISSDGTDFVLVLADMAPAEQG-
Mvan_3433|M.vanbaalenii_PYR-1 --YLSEVDFYAAINRDVAIPVPDCFHTEISTDGKDFVLVLADMAPAEQG-
MUL_1045|M.ulcerans_Agy99 RLAETEVSFYRDLSPELAPDAPTAYGCAFDPLTGRFVLVLEDLAAPAEGT
MAB_4589c|M.abscessus_ATCC_199 ------------ALSTAQVRVPRVTLASTDAEIFGAPFYLMERQDGEVIR
.* : : :
Mb3193|M.bovis_AF2122/97 ----PDVMPYTFGDNWFADAPAERQRQLQDATVAALATLHSIPNAQNTFS
Rv3168|M.tuberculosis_H37Rv ----PDVMPYTFGDNWFADAPAERQRQLQDATVAALATLHSIPNAQNTFS
MAV_1568|M.avium_104 ----DQLLGCGETEARLAVTALAG-LHAPSWCDPVWLDFPGIAFGRP-DE
MMAR_4035|M.marinum_M ----DQLTGCGEREARLAVVALAG-LHGPSWCDPVWLDQPGIAFPFP-DE
MSMEG_3876|M.smegmatis_MC2_155 ----DQIAGCSPAEAALAVRALAD-LHGPTWCDPQWANFPGIAMPKP-EP
TH_0441|M.thermoresistible__bu ----DQIVGCSPAEARLAVTALAG-LHGPSWCDPQWADVPGIAMPKP-DD
Mflv_3102|M.gilvum_PYR-GCK ----DQIAGCTAAEAALAVEAIAG-LHGPSWGDRRYFDLPSIVMPKPGDE
Mvan_3433|M.vanbaalenii_PYR-1 ----DQIAGCTPAEAALAVEALAG-LHGPSWNERRYFDLPSIVMPKPGDE
MUL_1045|M.ulcerans_Agy99 CDFSDTLHPFDNDQAALVVELLAR-LHATYWVRLNHGGVRPFGWRYAASR
MAB_4589c|M.abscessus_ATCC_199 DVSPEWFVGSARRELVLDLAVALAEIHNADPTR---------------LV
. : : :
Mb3193|M.bovis_AF2122/97 FLTQGRTSDTTLHRHFNWVRSWYDFAVEG-IGRSPLLERTFEWLQSHWPD
Rv3168|M.tuberculosis_H37Rv FLTQGRTSDTTLHRHFNWVRSWYDFAVEG-IGRSPLLERTFEWLQSHWPD
MAV_1568|M.avium_104 AGAGGMGEVAKMSADITLERLGDRMSAEDRETFAAAMGVIAPWLLSEY--
MMAR_4035|M.marinum_M PFANGLGEVARMSAEITLDKLGDRLSAADRETFTETMNLVTPWLLAER--
MSMEG_3876|M.smegmatis_MC2_155 DSAKGFGDIAKMAADITLDKLGDRLSIGDRETLSASMSVVTPWLLAEP--
TH_0441|M.thermoresistible__bu AAAEGLGEIAEMAADITIDKLGPRMRPEDRETTLTAMSMVTAWLRTEK--
Mflv_3102|M.gilvum_PYR-GCK AAASGMGEVAVMAANMTLEKLGGSVDDEDRDTLLTSMSLVTPWLMAVP--
Mvan_3433|M.vanbaalenii_PYR-1 AAAAGMGEVAKMAADITLDKLGGSVSDEDRDTLVTSMSLVTPWLLAVP--
MUL_1045|M.ulcerans_Agy99 DPSVPLVPTMLRASWRRLGGHAAAL-LPGRDFVFEHYRAITGLIDAPP--
MAB_4589c|M.abscessus_ATCC_199 EAKLGRESGYLARQLKTWGGQWESIKELPTGRDLQDHTTITAWLTENYPG
. :
Mb3193|M.bovis_AF2122/97 DAAAREPVLLWGDARVGNVLYR-DFQPVAV--LDWEMVALGPRELDVAWM
Rv3168|M.tuberculosis_H37Rv DAAAREPVLLWGDARVGNVLYR-DFQPVAV--LDWEMVALGPRELDVAWM
MAV_1568|M.avium_104 ----DRFALLHGDYRLDNLLFDPDRTRVSV--VDWQTLGVGLPARDLAYF
MMAR_4035|M.marinum_M ----DRFALLHGDYRLDNLLFDPDLRRVAV--VDWQTLGIGLPARDLGYF
MSMEG_3876|M.smegmatis_MC2_155 ----DRFAVLHGDYRLDNMLFDPDRTRVTV--VDWQTLGSGLPARDLSYF
TH_0441|M.thermoresistible__bu ----SRFALMHGDYRLDNMLFDPDRTRVTV--VDWQTMGAGLPARDLSYF
Mflv_3102|M.gilvum_PYR-GCK ----DRFSLMHGDYRLDNLLYDPERTRVTV--VDWQTVGIGLPTRDLAYF
Mvan_3433|M.vanbaalenii_PYR-1 ----DRFSLMHGDYRLDNLLYDPDRTRVTV--VDWQTMGIGLPSRDLAYF
MUL_1045|M.ulcerans_Agy99 ------HTVLHGDAHPGNWYFRSSGGPLAAGLLDWQAIRLGHPARDLAYT
MAB_4589c|M.abscessus_ATCC_199 D---RPAAVVHGDYKLDNVLVDPATARITA-VLDWEMATVGDPLADLGYL
:: ** : .* ::. :**: * *:.:
Mb3193|M.bovis_AF2122/97 IFAHRVFQELAGLATLPGLPEVMREDDVRATYQALTGVELGDLHWFYVYS
Rv3168|M.tuberculosis_H37Rv IFAHRVFQELAGLATLPGLPEVMREDDVRATYQALTGVELGDLHWFYVYS
MAV_1568|M.avium_104 TATS-----LDSPLRAAIEEELVADYHRALVAGGVNGYDR-ETCWRDYRL
MMAR_4035|M.marinum_M TATS-----LNSQLRSDIEESLVDDYHRKLLSYGVTGYDW-ETCWRDYRL
MSMEG_3876|M.smegmatis_MC2_155 TATS-----LDPADRAAAERDLVGEYHRTLLAHGVTGYDR-ETCWRDYRL
TH_0441|M.thermoresistible__bu LGTS-----LLPEVRSEVERDLVEVYHRALRSHGVADYDS-ETCWRDYRL
Mflv_3102|M.gilvum_PYR-GCK TATS-----LLPDDRAAVERDLVQRYHAALLAHGVSGYDV-ETCWQDYRL
Mvan_3433|M.vanbaalenii_PYR-1 TATS-----LLPETRAEVERDLVEHYHAALLGHGVSGYDV-ETCWHDYRL
MUL_1045|M.ulcerans_Agy99 LITG-----MTTTDRRVTERELLDVYRRALAAAGGPELDR-EEPWLRYRQ
MAB_4589c|M.abscessus_ATCC_199 LYMTP--EPGGEVAMSELTGSVTAQEGCPSHTEIAQAYREARSGDQSYWT
.:
Mb3193|M.bovis_AF2122/97 GVMWACVFMRTGARRVHFGEIEKPDDVESLFYHAGLMKHLLGEEH-----
Rv3168|M.tuberculosis_H37Rv GVMWACVFMRTGARRVHFGEIEKPDDVESLFYHAGLMKHLLGEEH-----
MAV_1568|M.avium_104 GVLQAPLISALGFAFAAATERGDDMVLTMLGRGCRAIRELGTLELIG---
MMAR_4035|M.marinum_M GMPHTVLISALGFAFATATERGDEMVLTMLGRGCQAIRDLETLELIG---
MSMEG_3876|M.smegmatis_MC2_155 GMLQAPLITVLGCAFASSTDRGDDMMVVMAQRGCQAIRELGTLDLIDAAS
TH_0441|M.thermoresistible__bu GMLQVPLLTVLGFAFAASTERGDDMMLTMLERGGRAIRELDSLELVNPAA
Mflv_3102|M.gilvum_PYR-GCK GVFQAPLITALGFAFAASTERGDEMILTMLHRGCRAIRELGAIDLVRSYQ
Mvan_3433|M.vanbaalenii_PYR-1 GVLQAPLITVLGTAFASSTERGDEMMLTMLHRGCRAIRELASIDLVRSYQ
MUL_1045|M.ulcerans_Agy99 AAACAYVATTIAAGLGG--MQAADIALTGLDLTVAALHDLQTVAALRAAD
MAB_4589c|M.abscessus_ATCC_199 PEDLVYYQVLGGWKLATLLEVSYQRHLAGTTDDPFFAELDEGVPRLLSVA
. . : .
Mb3193|M.bovis_AF2122/97 -------------------------------------------------
Rv3168|M.tuberculosis_H37Rv -------------------------------------------------
MAV_1568|M.avium_104 -------------------------------------------------
MMAR_4035|M.marinum_M -------------------------------------------------
MSMEG_3876|M.smegmatis_MC2_155 -------------------------------------------------
TH_0441|M.thermoresistible__bu S------------------------------------------------
Mflv_3102|M.gilvum_PYR-GCK ASTQPSSPTTA--------------------------------------
Mvan_3433|M.vanbaalenii_PYR-1 VS----SPTTA--------------------------------------
MUL_1045|M.ulcerans_Agy99 LGGTSWAWRPGMARSARIRPGASARRCPMVWSTSSHILGVSRHFAMGAW
MAB_4589c|M.abscessus_ATCC_199 RSLIPAAG-----------------------------------------