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IALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDPPALSEIMGRRVSSVSVLDDSSGTTSRARLALS GNDVPESVFVKMAAATAATRFIGELGRLAETEVSFYRDLSPELAPDAPTAYGCAFDPLTGRFVLVLEDLA APAEGTCDFSDTLHPFDNDQAALVVELLARLHATYWVRLNHGGVRPFGWRYAASRDPSVPLVPTMLRASW RRLGGHAAALLPGRDFVFEHYRAITGLIDAPPHTVLHGDAHPGNWYFRSSGGPLAAGLLDWQAIRLGHPA RDLAYTLITGMTTTDRRVTERELLDVYRRALAAAGGPELDREEPWLRYRQAAACAYVATTIAAGLGGMQA ADIALTGLDLTVAALHDLQTVAALRAADLGGTSWAWRPGMARSARIRPGASARRCPMVWSTSSHILGVSR HFAMGAW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1045 | - | - | 100% (428) | hypothetical protein MUL_1045 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4117 | - | 1e-116 | 58.92% (370) | hypothetical protein Mflv_4117 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4910c | - | 2e-05 | 41.18% (51) | putative aminoglycoside phosphotransferase |
| M. marinum M | MMAR_0395 | - | 0.0 | 97.92% (384) | hypothetical protein MMAR_0395 |
| M. avium 104 | MAV_5276 | - | 1e-115 | 58.82% (374) | phosphotransferase enzyme family protein |
| M. smegmatis MC2 155 | MSMEG_2554 | - | 1e-114 | 59.84% (371) | phosphotransferase enzyme family protein |
| M. thermoresistible (build 8) | TH_3005 | - | 8e-29 | 32.08% (371) | PUTATIVE putative protein of unknown function DUF227 |
| M. vanbaalenii PYR-1 | Mvan_2228 | - | 1e-122 | 61.02% (372) | aminoglycoside phosphotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_1045|M.ulcerans_Agy99 -------MIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDPPALS
MMAR_0395|M.marinum_M --MPENRVIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDAPALS
MAV_5276|M.avium_104 MKNPVGQAFSFLGLAAHLGRGAGRVSVDAVLGGRFGLPRTVDEIDPAVLS
MSMEG_2554|M.smegmatis_MC2_155 MLSTVRRIPPALALAAHIGHGVQRVAADAALGGLRRFPRRISDLDAGCLS
Mflv_4117|M.gilvum_PYR-GCK MSVLSERIAPAVGLASHLGRGVRRIGTDTLIGRLLPLPRTIGDLGPDAMS
Mvan_2228|M.vanbaalenii_PYR-1 MTVITQRIARAAGLAAHLGRALGRIGTDALIGRARALPRTVADLDAAAMS
TH_3005|M.thermoresistible__bu ------------------------MVHPALTIPPRWEDVTPEWMTAAIST
MAB_4910c|M.abscessus_ATCC_199 -----------------------MAAPHHIDPKSVDFDVVSHWMDEQGLP
: .
MUL_1045|M.ulcerans_Agy99 EIMGRRVSSVSVLDDSSGTTSRARLALSGND--VPESVFVKMAAATAATR
MMAR_0395|M.marinum_M EIMGRRVSSVSVLDDSSGTTSRARLALSGND--VPESVFVKMAAATAATR
MAV_5276|M.avium_104 RVMGTTVRTVRVLSRDAGTSSRARLVLTGKD--VPDSVFVKVAAQTAATR
MSMEG_2554|M.smegmatis_MC2_155 TIMGRTVRTLSVLGGDAGTSSRARLALSGDG--VPETVFVKLPAETAATR
Mflv_4117|M.gilvum_PYR-GCK SLMGRSVTSVAVLDGDAGTSSRARLALTGDG--VPATVFVKMAAETVATR
Mvan_2228|M.vanbaalenii_PYR-1 SVIGRAVTSVSVLDGDAGTSSRARLALTGDG--VPESVFVKMAAETVGTR
TH_3005|M.thermoresistible__bu RHPGATVERVTLLLRDDGTNRRARFELAYASGTGPRRVFVKAESGVPGRR
MAB_4910c|M.abscessus_ATCC_199 ---GGQLTDISAITG-GTQNIMVRFSRGGRE----------YVLRRPPKH
* : : : . .*: :
MUL_1045|M.ulcerans_Agy99 FIGELGRLAETEVSFYRDLSP---ELAPDAPTAYGCAFDPLTGRFVLVLE
MMAR_0395|M.marinum_M FIGELGRLAETEVSFYRDLSP---ELAPDAPTAYGCAYDPLTGRFVLVLE
MAV_5276|M.avium_104 LMGELGRLGCTEVRFYRQLAP---QVV-GVPYCYGAAFDAWTGRYLLVLE
MSMEG_2554|M.smegmatis_MC2_155 LMGELGRLAHTEVRFYQQLAA---GLP-GVPRAHGSAFDALTGRFVLVLE
Mflv_4117|M.gilvum_PYR-GCK LMGELGNLADTETRFYSRLSA---ELT-GVPRCHGSRFDPRTGRFVLILE
Mvan_2228|M.vanbaalenii_PYR-1 LMGELGNLAETETRFYRELSP---ELTTGVPLSYGSAFDPYTGRYILVLE
TH_3005|M.thermoresistible__bu EIHYENGNLFNESWLYRALLDGRTELPLEHPRAYAVAIDESALDYVIVFE
MAB_4910c|M.abscessus_ATCC_199 LREASNNVIRREARLLGALRG---QGVPAPELIAACTDETVLGGAVFYLM
. * : * . : :: :
MUL_1045|M.ulcerans_Agy99 DLAAPAEGTCDFSDTLHPFDNDQAALVVELLARLHATYWVRLN-HGGVRP
MMAR_0395|M.marinum_M DLAAPAEGTCDFSDTLHPFDNDQAALVVELLARLHATYWVRLN-HGGVRP
MAV_5276|M.avium_104 DLPA---EACEFPDTLHPLSADQAGLVVELLADLHATFWNRLP-RDGRGP
MSMEG_2554|M.smegmatis_MC2_155 DLAQ---EPCEFPDTLHPLDKDRAALTVELLARVHAAFWGRLPERSGRGP
Mflv_4117|M.gilvum_PYR-GCK DLADASAGPCDFPDTLHPIDADRAALVVELLARLHATFWGRLPERRGTGP
Mvan_2228|M.vanbaalenii_PYR-1 DLAG---GDCEFPDTLHPIDADRAALVVELLATVHATFWGRLPARGHAGP
TH_3005|M.thermoresistible__bu DLLER---SADPRDPTRPLTADQVADGLQGLARLHSRHWNRVGDEPELAW
MAB_4910c|M.abscessus_ATCC_199 EPVDGFNASVGLPELHAGNAEIRHQMGLEAVSGIAALGALDYQELGLDG-
: : : :: :: : :
MUL_1045|M.ulcerans_Agy99 FGWRYAASRDPSVPLVPTMLRASWRRLGGHAAALLPGRDFVFEHYRAITG
MMAR_0395|M.marinum_M FGWLYAASRDPSVPLVPTMLRASWRRLGGHAAALLPGRDYVFEHYRAITG
MAV_5276|M.avium_104 LGWLYTPSGDVTSLLTGSLMHSSIKRLAERTSIPVRDGVFIADNYRAVAA
MSMEG_2554|M.smegmatis_MC2_155 LGWLYSASGDDTSLLTGTLLKTSTRRLAERADIPVADGRFIDENYRAAAQ
Mflv_4117|M.gilvum_PYR-GCK LGWLYSASEDSASLLTAPLLRTSARRLAERTALPVGRGRFIDENYRAAAA
Mvan_2228|M.vanbaalenii_PYR-1 LGWLYSASGDSASLLTAPLLRTSARRLAERTPLPVHRGGFIDDNYRAIAS
TH_3005|M.thermoresistible__bu VQPFRPTRGWTAPMTAALPHGITAARDVLSDAVTHLDADGLVDVWTAYIG
MAB_4910c|M.abscessus_ATCC_199 ---YGNPDGFLERQVPRWLKELDSYAKHDGYPGPDIPGLQSVANWLERHR
. :
MUL_1045|M.ulcerans_Agy99 LIDAPPHTVLHGDAHPGNWYFRSSGGPLAAGLLDWQAIRLGHPARDLAYT
MMAR_0395|M.marinum_M LIDAPPHTVLHGDAHPGNWYFRSSGGPLAAGLLDWQAVRLGHPARDLAYT
MAV_5276|M.avium_104 LIDTAPHTVMHGDAHPGNMYFHGG----KAGLLDWQAVRRGHPSRELAYT
MSMEG_2554|M.smegmatis_MC2_155 LLDRPPHTVMHGDAHPGNLFFRNG----EAGLLDWQAVRRGHPGRELAYT
Mflv_4117|M.gilvum_PYR-GCK LIDRGPHTVMHGDAHPGNLYFRAG----QAGLLDWQAVRRGHPSRELAYT
Mvan_2228|M.vanbaalenii_PYR-1 LVDRPPHTVMHGDAHPGNLYFRDG----RAGLLDWQAVRRGHPGRELAYT
TH_3005|M.thermoresistible__bu GLGTGPQTFLHGDPHIGNTYLLPDD---TVGFLDWQVVRSGHWSHDVGYF
MAB_4910c|M.abscessus_ATCC_199 PSQWKPG-IMHGDFHLANMMFRNDG-PQLAAIVDWEMSTIGDPLLDLGWM
* .:*** * .* : . ..::**: *. ::.:
MUL_1045|M.ulcerans_Agy99 LITGMTTTDRRVTERELLDVYRRALAAAGGPELDREEPWLRYRQAAACAY
MMAR_0395|M.marinum_M LITGMTTTDRRVTERELLDVYRRALAAAGGPELDREELWLRYRQAAAYAY
MAV_5276|M.avium_104 LITSLTPEDRRATQRDLLDDYRRALAAAGGPQLDRDELWLRFRQAALYAY
MSMEG_2554|M.smegmatis_MC2_155 LITSMTTTDRQAAEKDLLDEYRRALAAAGGPRLDADELWERYRLGAVYAY
Mflv_4117|M.gilvum_PYR-GCK LTTSMTVEGRRGSQRDLLEVYRRALAAGGGPELDRDDLWDRYRQAALYPY
Mvan_2228|M.vanbaalenii_PYR-1 LVTSMTTEDRRRSERDLLDVYRRALAASGGPELDGDQLWDRYRQGAMYPY
TH_3005|M.thermoresistible__bu LQSALTEADRRAHEAALLAHYRNALQLPEIRRPTAEEAWLRYRASAAHGL
MAB_4910c|M.abscessus_ATCC_199 LATWPSETDDASLGGALVQAGGLPTPQELVAHYAERTDRDLGAMDWYTVL
* : : . *: . .
MUL_1045|M.ulcerans_Agy99 VATTIAAGLGGMQAADIALTGLDLTVAALHDLQTVAALRAADLGGTSWAW
MMAR_0395|M.marinum_M VATTIVAGLGGMQAADIALTGLDLTVAALHDLQTVAALRAADLGGTS---
MAV_5276|M.avium_104 AAPLITAGMGGMQVEDIAMEGLRRGVAALEDLETVAALKSSL--------
MSMEG_2554|M.smegmatis_MC2_155 TAPVITAGLGGMQDDGIAVEGARRGVAALADLETVALLKKLL--------
Mflv_4117|M.gilvum_PYR-GCK VATLITVGMGGMQVEDIAMKGLERALEALDDLETVALLEKNL--------
Mvan_2228|M.vanbaalenii_PYR-1 VATLITAGMGGMQDDGIALKGLERSLHALDDLDTVALLEKSL--------
TH_3005|M.thermoresistible__bu PVWLITL-LSDAHPTERSRALVQRFAAAFTDLDTPAAVQTLRRT------
MAB_4910c|M.abscessus_ATCC_199 ACFKLGIILEGTHARACAGKAPVAVGDYLHGLTLQLFKRAVAITG-----
: : . : : : .* .
MUL_1045|M.ulcerans_Agy99 RPGMARSARIRPGASARRCPMVWSTSSHILGVSRHFAMGAW
MMAR_0395|M.marinum_M -----------------------------------------
MAV_5276|M.avium_104 -----------------------------------------
MSMEG_2554|M.smegmatis_MC2_155 -----------------------------------------
Mflv_4117|M.gilvum_PYR-GCK -----------------------------------------
Mvan_2228|M.vanbaalenii_PYR-1 -----------------------------------------
TH_3005|M.thermoresistible__bu -----------------------------------------
MAB_4910c|M.abscessus_ATCC_199 -----------------------------------------