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HKDVSSDSDGPTGDAASLDADAIPTSLSEYLNRELGEQVSVRRLSAGHSNLTYVVTGSSGTQWILRRPPF GRLQAGAHDVMREYRVLDALSTAQVRVPRVTLASTDAEIFGAPFYLMERQDGEVIRDVSPEWFVGSARRE LVLDLAVALAEIHNADPTRLVEAKLGRESGYLARQLKTWGGQWESIKELPTGRDLQDHTTITAWLTENYP GDRPAAVVHGDYKLDNVLVDPATARITAVLDWEMATVGDPLADLGYLLYMTPEPGGEVAMSELTGSVTAQ EGCPSHTEIAQAYREARSGDQSYWTPEDLVYYQVLGGWKLATLLEVSYQRHLAGTTDDPFFAELDEGVPR LLSVARSLIPAAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4589c | - | - | 100% (364) | putative phosphotransferase |
| M. abscessus ATCC 19977 | MAB_0327 | - | 9e-32 | 29.68% (310) | aminoglycoside phosphotransferase |
| M. abscessus ATCC 19977 | MAB_4910c | - | 8e-31 | 29.45% (326) | putative aminoglycoside phosphotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3787c | fadE36 | 2e-35 | 30.77% (325) | acyl-CoA dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1204 | - | 2e-42 | 33.75% (323) | aminoglycoside phosphotransferase |
| M. tuberculosis H37Rv | Rv3761c | fadE36 | 2e-35 | 30.77% (325) | acyl-CoA dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_0155 | fadE36_1 | 7e-53 | 37.85% (362) | acyl-CoA dehydrogenase FadE36_1 |
| M. avium 104 | MAV_0316 | - | 1e-36 | 31.75% (315) | phosphotransferase enzyme family protein |
| M. smegmatis MC2 155 | MSMEG_6337 | - | 3e-41 | 32.50% (320) | phosphotransferase enzyme family protein |
| M. thermoresistible (build 8) | TH_2763 | - | 7e-52 | 38.33% (360) | PUTATIVE putative aminoglycoside phosphotransferase |
| M. ulcerans Agy99 | MUL_4942 | fadE36_1 | 5e-52 | 38.08% (344) | acyl-CoA dehydrogenase FadE36_1 |
| M. vanbaalenii PYR-1 | Mvan_5603 | - | 5e-40 | 33.78% (299) | aminoglycoside phosphotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1204|M.gilvum_PYR-GCK ----MT---ELEGLDLAALDR--------HLREVGVPRSGELRAELIAGG
Mvan_5603|M.vanbaalenii_PYR-1 ----MT---ELEGLDLAALDR--------HLCDVGVPRSGELRAEFISGG
MSMEG_6337|M.smegmatis_MC2_155 ----MT---SLEGLDLDALDR--------HLRAEGIARAGDLRAELIAGG
Mb3787c|M.bovis_AF2122/97 ----MTSVDRLDGLDLGALDR--------YLRSLGIGRDGELRGELISGG
Rv3761c|M.tuberculosis_H37Rv ----MTSVDRLDGLDLGALDR--------YLRSLGIGRDGELRGELISGG
MAV_0316|M.avium_104 ----MTSADQLEGLDLAALDS--------YLRSLGIGRDGELRAEFISGG
MMAR_0155|M.marinum_M --MPGPMSEDIPGVHAEAVSR--------WLVTLGHQVAAPLRFQRIGLG
MUL_4942|M.ulcerans_Agy99 ------MSEDIPGVHAHAVSR--------WLVTLGHQVAAPLRFQRIGLG
MAB_4589c|M.abscessus_ATCC_199 MHKDVSSDSDGPTGDAASLDADAIPTSLSEYLNRELG--EQVSVRRLSAG
TH_2763|M.thermoresistible__bu ---MTAARSDTPGEELVSVAA------LDDWLDDRLPGSGPLTVERITTG
. :: : . : *
Mflv_1204|M.gilvum_PYR-GCK RSNLTFLVGDDAS-EWVLRRPPLHGLTPSAHDMAREYKVVAALAGTKVPV
Mvan_5603|M.vanbaalenii_PYR-1 RSNLTFLVFDDAS-KWVLRRPPLHGLTPSAHDMAREYRVVAALADTAVPV
MSMEG_6337|M.smegmatis_MC2_155 RSNLTFLVFDDAS-KWVLRRPPLHGLTPSAHDMAREYRVVAALAGTPVPV
Mb3787c|M.bovis_AF2122/97 RSNLTFRVYDDAS-SWLVRRPPLHGLTPSAHDMAREYRVVAALGDTPVPV
Rv3761c|M.tuberculosis_H37Rv RSNLTFRVYDDAS-SWLVRRPPLHGLTPSAHDMAREYRVVAALGDTPVPV
MAV_0316|M.avium_104 RSNLTFRVYDDAT-SWLVRRPPLHGLTPSAHDMAREYRVVAALQDTPVPV
MMAR_0155|M.marinum_M QSNLTYRVTDAAGRAWVLRRPPLGHLLASAHDVVREARIMAALAETDVPV
MUL_4942|M.ulcerans_Agy99 QANLTYRVTDAAGRAWVLRHPPLGHLLASAHDVVREARIMAALAETDVPV
MAB_4589c|M.abscessus_ATCC_199 HSNLTYVVTGSSGTQWILRRPPFGRLQAGAHDVMREYRVLDALSTAQVRV
TH_2763|M.thermoresistible__bu HSNELFTVS-RGGPTWLLRRPPRVKNAPTAHDMVREYRVLTALEGTDVPH
::* : * . *::*:** . ***: ** ::: ** : *
Mflv_1204|M.gilvum_PYR-GCK ARAVTMSDDDSVLGAPFQMVERVAGLVVRHTPQLAALGDETVISNVVDSL
Mvan_5603|M.vanbaalenii_PYR-1 ARAVTMRNDDSVLGAPFQMVEYVAGRVVRHTDQLAALGDRATIEKCVDAL
MSMEG_6337|M.smegmatis_MC2_155 ARAVTMRNDDSVLGAPFQMVDHVDGRVVRTAAELAALGDQTVIDNCIDAL
Mb3787c|M.bovis_AF2122/97 ARTISLCQDDSVLGAPFQVVEFVAGQVVRRRAELEALGSRSVIEGCVDAL
Rv3761c|M.tuberculosis_H37Rv ARTISLCQDDSVLGAPFQVVEFVAGQVVRRRAELEALGSRSVIEGCVDAL
MAV_0316|M.avium_104 ARTIGLCEDESVLGAPFQIVEFVAGQVVRRRAQLESF-SHTVIEGCVDSL
MMAR_0155|M.marinum_M PRILGVTTDSEFSEAPLVLMEFVDGLVVDTMEVAEALTPRQRRQ-IALSL
MUL_4942|M.ulcerans_Agy99 PRILGVTTDSEFSEAPLVLMEFVDGLVVDTMEVAEALTPRQRRQ-IALSL
MAB_4589c|M.abscessus_ATCC_199 PRVTLASTDAEIFGAPFYLMERQDGEVIR--DVSPEWFVGSARRELVLDL
TH_2763|M.thermoresistible__bu ATPRGLCADPDVIGAPFYLMDKLAGVPLY--HELPASLAG-ERVAIAHAA
. * .. **: ::: * :
Mflv_1204|M.gilvum_PYR-GCK IQVLADLHEVDPESVGLGDFGKASGYLERQVRRWGSQWDLVK-RDDDPSD
Mvan_5603|M.vanbaalenii_PYR-1 IKVLADLHSVDPDAVGLSDFGKPSGYLERQVRRWGSQWDLVR-RADDPCD
MSMEG_6337|M.smegmatis_MC2_155 IKALSDLHAVDPYAVGLGDFGKPDGYLERQVRRWGSQWEHVR-LPDDARD
Mb3787c|M.bovis_AF2122/97 IRVLVDLHSIDPKAVGLSDFGKPDGYLERQVRRWGSQWELVR-LPDDHRD
Rv3761c|M.tuberculosis_H37Rv IRVLVDLHSIDPKAVGLSDFGKPDGYLERQVRRWGSQWELVR-LPDDHRD
MAV_0316|M.avium_104 IRVLVDLHSVDPDAVGLADFGKPSGYLERQVRRWGSQWALVR-LPEDRRD
MMAR_0155|M.marinum_M PRTLAKIHAVDLAKVGLDDLASHKPYAQRQLKRWAGQWELSK-TRELP--
MUL_4942|M.ulcerans_Agy99 PRTLAKIHAVDLAKVGLDDLASHKPYAQRQLKRWAGQWELSK-TRELP--
MAB_4589c|M.abscessus_ATCC_199 AVALAEIHNADPTRLVEAKLGRESGYLARQLKTWGGQWESIKELPTGRDL
TH_2763|M.thermoresistible__bu IDALAALHRLDWRAAGLDGFGKPDGYTERQAARWGKQLKSY----AFREL
.* :* * :. . * ** *. *
Mflv_1204|M.gilvum_PYR-GCK ADVRKLHQRLAESVPEQSRASIVHGDYRIDNTILDADDPTKVAAVLDWEM
Mvan_5603|M.vanbaalenii_PYR-1 ADVRRLHERLSAALPPQSRSSIVHGDYRIDNTILDAEDPTKVVAVLDWEM
MSMEG_6337|M.smegmatis_MC2_155 DDVRRLHAALADAVPPQSGTSIVHGDYRIDNTVLDAEDATVVRAVLDWEM
Mb3787c|M.bovis_AF2122/97 ADISRLHLALQQAIPQQSRTSIVHGDYRIDNTILDTDDPCHVRAVVDWEL
Rv3761c|M.tuberculosis_H37Rv ADISRLHLALQQAIPQQSRTSIVHGDYRIDNTILDTDDPCHVRAVVDWEL
MAV_0316|M.avium_104 ADVERLHSGLGQAIPQQSRTSIVHGDYRIDNTILDADDPTKVRAVVDWEL
MMAR_0155|M.marinum_M -ELDDLTRRLVAAAPEQREISLVHGDFHLRN-LITSPETGAVVATLDWEL
MUL_4942|M.ulcerans_Agy99 -ELDDLTRRLVAAAPEQREISLVHGDFHLRN-LITSPETGAVVATLDWEL
MAB_4589c|M.abscessus_ATCC_199 QDHTTITAWLTENYPGDRPAAVVHGDYKLDNVLVDP-ATARITAVLDWEM
TH_2763|M.thermoresistible__bu PELDEVAAWLDESCPGTRGSALIHGDYGLHNLLYAPEPPVRILAVVDWET
: : * * :::***: : * : . . : *.:***
Mflv_1204|M.gilvum_PYR-GCK STLGDPLSDAALMCVYRLPAFN-EVHDDAA---WACDLMPPTDDLAQRYA
Mvan_5603|M.vanbaalenii_PYR-1 STLGDPLSDAALMCVYRHPMFN-MVHADAA---WASELIPDADALADKYS
MSMEG_6337|M.smegmatis_MC2_155 STLGDPLSDAALMCVYRNPMFG-HIHTDAA---WSSDLVPPADELADRYS
Mb3787c|M.bovis_AF2122/97 STLGDPLSDAALMCVYRDPALDLIVHAQAA---WTSPLLPAADELADRYS
Rv3761c|M.tuberculosis_H37Rv STLGDPLSDAALMCVYRDPALDLIVHAQAA---WTSPLLPAADELADRYS
MAV_0316|M.avium_104 STLGDPLSDAALMCVYRDPALDLIVNAQAA---WTSPLLPTADELADRYS
MMAR_0155|M.marinum_M STLGDPLADMGSLLTYWMEPGESGVGDFAP---STLDGFPDRAEMTRLYL
MUL_4942|M.ulcerans_Agy99 STLGDPLADMGSLLTYWMEPGESGVGDFAP---STLDGFPDRAEMTRLYL
MAB_4589c|M.abscessus_ATCC_199 ATVGDPLADLGYLLYMTPEPGGEVAMSELTGSVTAQEGCPSHTEIAQAYR
TH_2763|M.thermoresistible__bu STIGDPLADLGYFLASWLEPD-EVAQWGELGSPHGVAGNPSRAELIERYA
:*:****:* . : * : *
Mflv_1204|M.gilvum_PYR-GCK LASGKP-----LDHWDFYMALGYFKIAIIAAGIAYRARMGGGVA---EGT
Mvan_5603|M.vanbaalenii_PYR-1 RAAGQP-----LDHWDFYMALAYFKLAIIGAGIAYRAREAG-VV---DDT
MSMEG_6337|M.smegmatis_MC2_155 KVSGRD-----LAHWDFYMALAYFKLAIIAAGIDYRRREGA------DGP
Mb3787c|M.bovis_AF2122/97 LVSGQP-----LGHWEFYMALAYFKLAIIAAGIDYRRRMSEQAEGKDTAA
Rv3761c|M.tuberculosis_H37Rv LVSGQP-----LGHWEFYMALAYFKLAIIAAGIDYRRRMSEQAEGKDTAA
MAV_0316|M.avium_104 LVAGIP-----LAHWEFYMALAYFKLAIIAAGIDFRRRMSDQARGLGEAA
MMAR_0155|M.marinum_M EETGRD-----PAALQYWHVLGLWKLAIIAEGVMRRAMDEPQNKASEGTP
MUL_4942|M.ulcerans_Agy99 EETGRD-----PAALQYWHVLGLWKLAIIAEGVMRRAMDEPQNKASEGTP
MAB_4589c|M.abscessus_ATCC_199 EARSGDQSYWTPEDLVYYQVLGGWKLATLLEVSYQRHLAGTTDDPFFAEL
TH_2763|M.thermoresistible__bu RKSGID---VTADDLVWYRVFGQFKLAVIFEGSYGRYVRGQSADPFFASL
. :: .:. :*:* : *
Mflv_1204|M.gilvum_PYR-GCK DEVDRAVRPFVAAGLHILS----------
Mvan_5603|M.vanbaalenii_PYR-1 DKVGEAVAPLIAAGLSQLA----------
MSMEG_6337|M.smegmatis_MC2_155 EQVGEAVAPMIAAGLAALG----------
Mb3787c|M.bovis_AF2122/97 ESVPDVVAPLIARGLAEIAKKSG------
Rv3761c|M.tuberculosis_H37Rv ESVPDVVAPLIARGLAEIAKKSG------
MAV_0316|M.avium_104 EHTPEVVAPLISRGLAELAKLPG------
MMAR_0155|M.marinum_M TVAWIDARVHMAREIADAAGMNQVSDSAS
MUL_4942|M.ulcerans_Agy99 TVAWIDARVHMAREIADAAGMNQVSDSAF
MAB_4589c|M.abscessus_ATCC_199 DEGVPRLLSVARSLIPAAG----------
TH_2763|M.thermoresistible__bu ERRVPLLARHALAIAAGEA----------
.