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M. thermoresistible (build 8) TH_3623 (-)

annotation: putative aminoglycoside phosphotransferase
coordinates: 40663 - 41742
length: 360

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_3623 - - 100% (360) putative aminoglycoside phosphotransferase
M. thermoresistible (build 8) TH_0441 - 1e-55 37.93% (348) phosphotransferase enzyme family protein, putative
M. thermoresistible (build 8) TH_2511 - 2e-46 34.66% (352) PUTATIVE protein of unknown function DUF227

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 - - - - -
M. gilvum PYR-GCK Mflv_3155 - 2e-51 35.33% (351) hypothetical protein Mflv_3155
M. tuberculosis H37Rv - - - - -
M. leprae Br4923 - - - - -
M. abscessus ATCC 19977 - - - - -
M. marinum M MMAR_4035 - 3e-51 34.58% (347) hypothetical protein MMAR_4035
M. avium 104 MAV_2467 - 2e-48 33.24% (358) phosphotransferase enzyme family protein
M. smegmatis MC2 155 MSMEG_3876 - 2e-52 36.62% (355) phosphotransferase enzyme family protein, putative
M. ulcerans Agy99 MUL_1045 - 3e-17 25.07% (351) hypothetical protein MUL_1045
M. vanbaalenii PYR-1 Mvan_3374 - 7e-50 35.04% (351) aminoglycoside phosphotransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3155|M.gilvum_PYR-GCK          --MADRPLLYLGRVCSLTRPQLIERPADLTAEWLTDILG--HGQVESFTV
Mvan_3374|M.vanbaalenii_PYR-1       -----------------MRPRLIERPPDLTAEWLTAVIG--QGTVTEFTV
MAV_2467|M.avium_104                --------------MHAETEQVIERPSDLSASWLAAVIG--TGPIADFSV
TH_3623|M.thermoresistible__bu      --------------MAFTDYTIAELTPEALAAVLRRRPG--WEALTVTTV
MMAR_4035|M.marinum_M               ------------------MVSIPRHPTDVTPQWLAAVLGERGTPVGVSGV
MSMEG_3876|M.smegmatis_MC2_155      ---------------MTAAVSIPGRPVDVTPSWLSGVLG-----TEVATA
MUL_1045|M.ulcerans_Agy99           MIALARLATHLGRGLGRVATDAVLRNARAFPRRIHDLDPPALSEIMGRRV
                                                                  .  :               .

Mflv_3155|M.gilvum_PYR-GCK          DR--IGTGQMSECYRVGIRYAGGGV-GPASVVLKVAAAEPSSRQTGLAMG
Mvan_3374|M.vanbaalenii_PYR-1       DR--IGTGQMSECYRVALSYADDGA-GPATVVLKVAAADPSSRQTGLAMG
MAV_2467|M.avium_104                ER--IGTGQMSECYRIRLRYAQADARGPESVVLKVAATDPVSRQTGLALG
TH_3623|M.thermoresistible__bu      ESQPVGTGQMASSYRLTLGYAGDSGSAPDTLIAKISSTDETSWQMAVATG
MMAR_4035|M.marinum_M               DVVPIGTGQTGATYRLTVIYDPDPAGLPDTFVIKLPAQDDTVRDRVVVG-
MSMEG_3876|M.smegmatis_MC2_155      ATEPIGTGQTGATYRVTVTYAGDSA-LPTTFAIKLPSQDDTVRDRVAIG-
MUL_1045|M.ulcerans_Agy99           SSVSVLDDSSGTTSRARLALSGNDV--PESVFVKMAAATAATRFIGELGR
                                        :  .. .   *  :         * :.  *:.:             

Mflv_3155|M.gilvum_PYR-GCK          LYEREVRFYTDIAPSLGGPVAPCHHTAYDPDTGAFDLVLADAAPASVG--
Mvan_3374|M.vanbaalenii_PYR-1       LYEREVRFYTDIAPGLGGPVAPCHHGAYDPHTGAFDLLLADAAPALVG--
MAV_2467|M.avium_104                LYEREVRFYGDVAPRLGGPIAPCYHAAVDTSTGVFDLLLGDAGPAVVG--
TH_3623|M.thermoresistible__bu      AYEREVRYYQHLSGLAATRTPECYFAEIADDRCGFALLLEDMGPADTI--
MMAR_4035|M.marinum_M               -YRSECAFYSSVADRVRVPTPRCFYCEITEDAMDFALLLEDQAPAVQG--
MSMEG_3876|M.smegmatis_MC2_155      -YRSEHAFYTSLAGQVRIPVPHCYHCEIAGEGADFVLVLADMAPAEQG--
MUL_1045|M.ulcerans_Agy99           LAETEVSFYRDLSPELAPDAPTAYGCAFDPLTGRFVLVLEDLAAPAEGTC
                                      . *  :*  ::       . ..          * *:* * ...     

Mflv_3155|M.gilvum_PYR-GCK          ---DEIRGATAEQASLAMTQLGLVHGPLLGSEALEGADWLNRESPVN---
Mvan_3374|M.vanbaalenii_PYR-1       ---DEIRGATVEEAMLAVTQIGLVHGPLLNDEALAGADWLNRESPVN---
MAV_2467|M.avium_104                ---DEIAGATIEQARLGVVELGRLHGPLLGDISLAQAPWLNRDAPLN---
TH_3623|M.thermoresistible__bu      ---DQISGCTADQADLALGQAAALHGSSWAHAALRDNDWLPAQGAWAK--
MMAR_4035|M.marinum_M               ---DQLTGCGEREARLAVVALAGLHGPSWCDPVWLDQPGIAFPFPDEPFA
MSMEG_3876|M.smegmatis_MC2_155      ---DQIAGCSPAEAALAVRALADLHGPTWCDPQWANFPGIAMPKPEPDSA
MUL_1045|M.ulcerans_Agy99           DFSDTLHPFDNDQAALVVELLARLHATYWVRLNHGGVRPFGWRYAASR--
                                       * :      :* * :   . :*..            :    .     

Mflv_3155|M.gilvum_PYR-GCK          ---QGLVAALYAGYIDRYSDQIAPEH--RVVCERLVASFDAYMAAEDAAG
Mvan_3374|M.vanbaalenii_PYR-1       ---QGLISALYAGYIDRYREQIAPEH--RNVCERFVESFDAYMAAENDAD
MAV_2467|M.avium_104                ---QAMIAPLYAGFVERYGDQIAPEH--RAVCERLVAAFDGYLAQE---P
TH_3623|M.thermoresistible__bu      --LADAIPHITPMWLDRFGAHLRPEH--IPVVEQLGDHVSAWLETLT---
MMAR_4035|M.marinum_M               NGLGEVARMSAEITLDKLGDRLSAAD--RETFTETMNLVTPWLLAER---
MSMEG_3876|M.smegmatis_MC2_155      KGFGDIAKMAADITLDKLGDRLSIGD--RETLSASMSVVTPWLLAEP---
MUL_1045|M.ulcerans_Agy99           DPSVPLVPTMLRASWRRLGGHAAALLPGRDFVFEHYRAITGLIDAPP---
                                                    :   :                 .   :       

Mflv_3155|M.gilvum_PYR-GCK          GPRGLVHGDFRLDNMLFGQDGSDRPLTVVDWQTVTWGPAFTDVSYFLGGS
Mvan_3374|M.vanbaalenii_PYR-1       TPRGLVHGDYRLDNMLFGQDGAHRPLTVVDWQTVTWGPAFSDVAYFLGCA
MAV_2467|M.avium_104                GVRGLVHGDYRLDNMLFGTAGAERALTVVDWQTVSWGPALTDLAYFLGCA
TH_3623|M.thermoresistible__bu      EHRSLWHGDFRLDNLLFGAQAGATPIAVVDWQSVASGPGVIDVSYFLGNS
MMAR_4035|M.marinum_M               DRFALLHGDYRLDNLLFDPD--LRRVAVVDWQTLGIGLPARDLGYFTATS
MSMEG_3876|M.smegmatis_MC2_155      DRFAVLHGDYRLDNMLFDPD--RTRVTVVDWQTLGSGLPARDLSYFTATS
MUL_1045|M.ulcerans_Agy99           --HTVLHGDAHPGNWYFRSSGGPLAAGLLDWQAIRLGHPARDLAYTLITG
                                        : *** : .*  *          ::***::  *    *:.*    .

Mflv_3155|M.gilvum_PYR-GCK          LPIEERRAHYDELLAAYHRALGEA--TGVSLDDVREGVRHQSFFGVLMAI
Mvan_3374|M.vanbaalenii_PYR-1       LPVEQRREHYDALLAAYHGALGPT--AGVSIDEVREGVRRQSFFGVLMSI
MAV_2467|M.avium_104                LPTEDRREHYDALLRAYHEALGPQ--PPITLADVADGVRRQSFFGVMMAI
TH_3623|M.thermoresistible__bu      MTEDHRAEHERELVGEYHRRLLSHGVQGYSADRCWLEYRAHAVFGLMLTV
MMAR_4035|M.marinum_M               LNSQLRSDIEESLVDDYHRKLLSYGVTGYDWETCWRDYRLGMPHTVLISA
MSMEG_3876|M.smegmatis_MC2_155      LDPADRAAAERDLVGEYHRTLLAHGVTGYDRETCWRDYRLGMLQAPLITV
MUL_1045|M.ulcerans_Agy99           MTTTDRRVTERELLDVYRRALAAAGGPELDREEPWLRYRQAAACAYVATT
                                    :    *      *:  *:  *                 *       : : 

Mflv_3155|M.gilvum_PYR-GCK          VSSMLVGRTERGDEMFMALIARHCQHVLDTDALAILPAPSTPEPLQPNAD
Mvan_3374|M.vanbaalenii_PYR-1       VSPMLVERTERGDEMFMAMIARHCQHVIDTGALAVLPEPGTPEPLQPNAD
MAV_2467|M.avium_104                VSSMLVERTDRGDQMFMTMLRRHCDHVLDTDALATLPAASAPEPLQPSPE
TH_3623|M.thermoresistible__bu      PVSLGVQATERGDKMFAAMATRAAAQILENESYTALKCL-----------
MMAR_4035|M.marinum_M               LGFAFATATERGDEMVLTMLGRGCQAIRDLETLELIG-------------
MSMEG_3876|M.smegmatis_MC2_155      LGCAFASSTDRGDDMMVVMAQRGCQAIRELGTLDLIDAAS----------
MUL_1045|M.ulcerans_Agy99           IAAGLGG--MQAADIALTGLDLTVAALHDLQTVAALRAADLGGTSWAWRP
                                              :. .:  .        : :  :   :              

Mflv_3155|M.gilvum_PYR-GCK          DEGRHAPTEEPLWSESWYFDFAAPSQDIGGWIRLGLMPNEGHAWVNGLLC
Mvan_3374|M.vanbaalenii_PYR-1       DEGRHSPTDEALWSESWYFDFADPGQQLGGWIRLGLIPNQDHAWINGLWC
MAV_2467|M.avium_104                DELAHDPTTEPLWSESWYADFADPAQGLGGWFRLGLVANQQTAWVHALVC
TH_3623|M.thermoresistible__bu      --------------------------------------------------
MMAR_4035|M.marinum_M               --------------------------------------------------
MSMEG_3876|M.smegmatis_MC2_155      --------------------------------------------------
MUL_1045|M.ulcerans_Agy99           GMARSARIRPGASARRCPMVWSTSSHILGVSRHFAMGAW-----------
                                                                                      

Mflv_3155|M.gilvum_PYR-GCK          GPGMPTIAALDFEAPLPEEHTRVHGQDIELEQTVIEPLQTYQVTVRGRGQ
Mvan_3374|M.vanbaalenii_PYR-1       APGGPTIAVLDFEAPLPEDHTHVAADGIELDLEVLEPLSSYRVVLRGRGE
MAV_2467|M.avium_104                GPDMPTVAV-DAQVPLPPDPWTVRTDTFEITHSAGAPLRSYRVDVRALAQ
TH_3623|M.thermoresistible__bu      --------------------------------------------------
MMAR_4035|M.marinum_M               --------------------------------------------------
MSMEG_3876|M.smegmatis_MC2_155      --------------------------------------------------
MUL_1045|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mflv_3155|M.gilvum_PYR-GCK          AHDDPAALLRGEPGRDVEVTMDLTWTSVGQPYQYRVSPRYEIPCTVTGTV
Mvan_3374|M.vanbaalenii_PYR-1       AHDDPAALLRGEAGRPVDVSMDLTWSTVGRPYQYRMSPRYEIPCTVTGTV
MAV_2467|M.avium_104                AYADPAALLRGEPGTPVAMTMNLDWHTDGTPYKYAMTTRYEIPCTVTGSV
TH_3623|M.thermoresistible__bu      --------------------------------------------------
MMAR_4035|M.marinum_M               --------------------------------------------------
MSMEG_3876|M.smegmatis_MC2_155      --------------------------------------------------
MUL_1045|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mflv_3155|M.gilvum_PYR-GCK          SADGHTYEFDAVVGQRDHSWAARDWWAMDWVWSAFHLEDGTHIHGVEILI
Mvan_3374|M.vanbaalenii_PYR-1       VADGRTYAIAGVPGQRDHSWAARDWWSMDWMWSALHLDDGTHIHGVEILI
MAV_2467|M.avium_104                TIGDTAYRIESVAGQRDHSWGVRDWWSMDWIWSALHLDDGTHLHGVNIRI
TH_3623|M.thermoresistible__bu      --------------------------------------------------
MMAR_4035|M.marinum_M               --------------------------------------------------
MSMEG_3876|M.smegmatis_MC2_155      --------------------------------------------------
MUL_1045|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mflv_3155|M.gilvum_PYR-GCK          PGAPPMSIGYLQRAGEPLVELSSVSAQTTFADNDLPQSAVLDYG--DLRV
Mvan_3374|M.vanbaalenii_PYR-1       PGMPPLAVGYVQRDGESLVELAKVSARTTFADNGLPISAQVDYAPGDITA
MAV_2467|M.avium_104                PGAPAFSIGYTQGADGEVTELQTVDSRESFGDNGLPLDATLELNPGEITA
TH_3623|M.thermoresistible__bu      --------------------------------------------------
MMAR_4035|M.marinum_M               --------------------------------------------------
MSMEG_3876|M.smegmatis_MC2_155      --------------------------------------------------
MUL_1045|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mflv_3155|M.gilvum_PYR-GCK          DVTVRGHAPVLLTSADGRLSQFPRAWATVTTDDGRTGAGWIEWNRNLAQP
Mvan_3374|M.vanbaalenii_PYR-1       TIDVRGHAPVLLTSPDGRHSRFPRAWGEVTTADGRTGVGWIEWNRSQD--
MAV_2467|M.avium_104                QVDVRGQAPVRLVAADGRVSQFPRVWAAVSTGDGRRGVGWLEWNRNLGER
TH_3623|M.thermoresistible__bu      --------------------------------------------------
MMAR_4035|M.marinum_M               --------------------------------------------------
MSMEG_3876|M.smegmatis_MC2_155      --------------------------------------------------
MUL_1045|M.ulcerans_Agy99           --------------------------------------------------
                                                                                      

Mflv_3155|M.gilvum_PYR-GCK          DG
Mvan_3374|M.vanbaalenii_PYR-1       --
MAV_2467|M.avium_104                IG
TH_3623|M.thermoresistible__bu      --
MMAR_4035|M.marinum_M               --
MSMEG_3876|M.smegmatis_MC2_155      --
MUL_1045|M.ulcerans_Agy99           --

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_3623	-	-	100% (360)	putative aminoglycoside phosphotransferase
M. thermoresistible (build 8)	TH_0441	-	1e-55	37.93% (348)	phosphotransferase enzyme family protein, putative
M. thermoresistible (build 8)	TH_2511	-	2e-46	34.66% (352)	PUTATIVE protein of unknown function DUF227