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M. thermoresistible (build 8) TH_0276 (-)

annotation: transcriptional regulator, TetR family protein
coordinates: 618992 - 619561
length: 190

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0276--100% (190)transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_0275-1e-5663.91% (169) transcriptional regulator, TetR family protein
M. thermoresistible (build 8)TH_2255-6e-0831.58% (114) TetR-family protein transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2184c-2e-0625.44% (169) hypothetical protein Mb2184c
M. gilvum PYR-GCKMflv_4112-5e-6374.05% (158) TetR family transcriptional regulator
M. tuberculosis H37RvRv1255c-2e-0625.38% (197) transcriptional regulatory protein
M. leprae Br4923MLBr_00064-4e-0540.74% (54) putative transcriptional regulator
M. abscessus ATCC 19977MAB_0098-2e-0851.06% (47) TetR family transcriptional regulator
M. marinum MMMAR_0389-1e-5664.42% (163) putative regulatory protein
M. avium 104MAV_5134-2e-5765.03% (163) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_2557-7e-6574.53% (161) transcriptional regulator, TetR family protein
M. ulcerans Agy99MUL_1039-7e-5764.42% (163) putative regulatory protein
M. vanbaalenii PYR-1Mvan_2233-1e-6274.68% (158) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4112|M.gilvum_PYR-GCK          ----MTMPSP---APGSAD-PDNPTRQRILAATAEVLGRNGTTRLSLSEV
Mvan_2233|M.vanbaalenii_PYR-1       ----MPQPPPGDRGPQSADDPDSPTRQRILAATAEVLGRNGTTKLSLSEV
MSMEG_2557|M.smegmatis_MC2_155      ----MAGTDAG----TDAGTEASSTRERILAATAKVLGSNGTTKLSLSDV
TH_0276|M.thermoresistible__bu      ----MP------------DRIAASARERILTATAEVLGRAGMTKLSLSDV
MMAR_0389|M.marinum_M               ----MSQAFG----AIDTTDGDTSTRQRILAATAEVLARSGKTKLSLSEV
MUL_1039|M.ulcerans_Agy99           ----MSQAFG----AIDTTDGDTSMRQRILAATAEVLARSGKTKLSLSEV
MAV_5134|M.avium_104                ----MSHPVR----ATAIADTDTSTRQRILAATAEVLGRNGKTKLSLSDV
MAB_0098|M.abscessus_ATCC_1997      ----MKLVKT--------TGPRGEVPEPIVAAVAQTLVRSGIQRFSLSAA
Mb2184c|M.bovis_AF2122/97           ---------------MPSADVGRQTRAQILRAAMDIASVKGLSGLSIGEL
Rv1255c|M.tuberculosis_H37Rv        ----MAGTDWLS------ARRTELAADRILDAAERLFTQRDPASIGMNEI
MLBr_00064|M.leprae_Br4923          MINSTAGQTSQSRSRRSTRPSGDDRELAILATAEQLLEDRPLTEISVDYL
                                                                *: :.           :.:.  

Mflv_4112|M.gilvum_PYR-GCK          AAQAGVSRPTLYRYFADKRELLDVFVVWERQYYERAIAK-ATAELPA-HE
Mvan_2233|M.vanbaalenii_PYR-1       ASQAGVSRPTLYRYFADKRELLDVFVVWERQYYERAIAR-ATADLPV-SE
MSMEG_2557|M.smegmatis_MC2_155      ASQAGVSRPTLYRWFSSKQDLLDAFVVWERRGYEQAVAQ-ATGALPA-SE
TH_0276|M.thermoresistible__bu      AQQAGVSRPTLYRWFSGKEELLDAFAQWERQMYERALAE-ATAGLPA-EE
MMAR_0389|M.marinum_M               AAQAGVSRPTLYRWFASKEELLATFSRYERQVFESGLSK-ATAGLKG-VD
MUL_1039|M.ulcerans_Agy99           AAQAGVSRPTLYRWFASKEELLATFSRYERQVFESGLSK-ATAGLKG-VD
MAV_5134|M.avium_104                ATQAGVSRPTLYRWFASKEELLSAFSAYERQIFESGLVK-ATAGLKG-VD
MAB_0098|M.abscessus_ATCC_1997      ADEAGVSRGTIYNWFGGKKEAIDVAVGFIAGAFIELFAG-AVSAKTT-LT
Mb2184c|M.bovis_AF2122/97           AGRLGMSKSGLFRHFGAKEQLQLATVEAAVSVFEAEVVAPAMAAPPG-VD
Rv1255c|M.tuberculosis_H37Rv        AKAAGCSRATLYRYFDSREALRTAYVHRETRRLGREIMVKIADVVEP-AE
MLBr_00064|M.leprae_Br4923          AKSAGISRPTFYFYFASKEAVLLTLLDRVFNKANAALETLIKNRDNKRGN
                                    *   * *:  ::  *  :.    .            .             

Mflv_4112|M.gilvum_PYR-GCK          RLDAALRVIVEYQL--SYPG-------------MRMVDVEPDQVIRRMSR
Mvan_2233|M.vanbaalenii_PYR-1       RLDAALRVIVEYQL--SYPG-------------LRMVDVEPDQVIKRLTR
MSMEG_2557|M.smegmatis_MC2_155      RLDAALRVIAEYQR--SYPG-------------LRMVDIEPEHVIRRLSQ
TH_0276|M.thermoresistible__bu      RLDAVLRVIVEYQQ--SYPG-------------LRMVDIEPAHLIGRLSA
MMAR_0389|M.marinum_M               KLDAALRFIVDYQY--SYSG-------------VRMVDIEPELVISQMSG
MUL_1039|M.ulcerans_Agy99           KLDAALRFIVDYQY--SYSG-------------VRMVDIEPELVISQMSS
MAV_5134|M.avium_104                KLDAVLRFIVDYQH--SYSG-------------VRMVDVEPEHTIAQFSW
MAB_0098|M.abscessus_ATCC_1997      DQVGEAAVRISDHR--AWSDRLDPTLHVSNVLELVLEECGDDLMRRSVEF
Mb2184c|M.bovis_AF2122/97           RVRALMHAWVGYLERDVFPGG------CFFAAAAADVDSQPGPVRDRIAA
Rv1255c|M.tuberculosis_H37Rv        RLLVSITTTLRMVR--DNPAL------------AAWFTTTRPPIGGEMAG
MLBr_00064|M.leprae_Br4923          KWRTGINVFFETFG--SHKAVT----------CAGQVTRDNTEVRKLWST
                                                                                      

Mflv_4112|M.gilvum_PYR-GCK          -----VLPLMRERLERLCTGPDAALSAATAVRVAISQYLVRSDDSADFLA
Mvan_2233|M.vanbaalenii_PYR-1       -----VLPLMRDRLQRLCTGPDAALAAATAVRVAISQYLVRSDDSEQFLA
MSMEG_2557|M.smegmatis_MC2_155      -----IMPLLRERLQRLTTGPDSDVAAATAVRVAISHYLVRSDDADDFLA
TH_0276|M.thermoresistible__bu      -----ILPVMRDRLERLCTGPTASAAAATAVRVAVSHYLVQSDDAGDFLA
MMAR_0389|M.marinum_M               -----VIPEMREGLQRLLPGPNAAVKAATAIRIAISHYIVRSDDADQFLA
MUL_1039|M.ulcerans_Agy99           -----VIPEMREGLQRLLPGPNAAVKAATAIRIAISHYIVRSDDADQFLA
MAV_5134|M.avium_104                -----VIPQMREGLQRHLPGPNAAVKAATVIRIAISHYIVRSDDADQFLA
MAB_0098|M.abscessus_ATCC_1997      -----WVPQVEAAKHRGEIGGDVDATEAAEWIMRTLMSIEVLPAISVDLT
Mb2184c|M.bovis_AF2122/97           TGRAGIAAITADVETAQRRGEIRADIEARQLAFELHAYAMEANWALLLLD
Rv1255c|M.tuberculosis_H37Rv        RSE-VIAALAAAFLNSLGPDDPTTVERRARWVVRMLTSLLMFPGRDEADE
MLBr_00064|M.leprae_Br4923          FMQKWISYTAAVIDAERKRGVAPDTLPATELATALNLMNERALFASFTAE
                                                       .                              

Mflv_4112|M.gilvum_PYR-GCK          QLRHAARV--------------RHPGR-
Mvan_2233|M.vanbaalenii_PYR-1       QLRHAARV--------------KHRDM-
MSMEG_2557|M.smegmatis_MC2_155      QLRHVARP--------------RRRE--
TH_0276|M.thermoresistible__bu      QLRHAVGLPIAPGAVSAKTPLQPRRNP-
MMAR_0389|M.marinum_M               QLRHAVGL--------------KGG---
MUL_1039|M.ulcerans_Agy99           QLRHAVGL--------------KGG---
MAV_5134|M.avium_104                QLRHAVGI--------------KAPTD-
MAB_0098|M.abscessus_ATCC_1997      DPNRVRRYFSR--------FILRGLA--
Mb2184c|M.bovis_AF2122/97           DDGAGERARTAIDAALARVGTTQEGVES
Rv1255c|M.tuberculosis_H37Rv        RAMIAEFVVPIVTPASAAARKAGHPGPE
MLBr_00064|M.leprae_Br4923          QPHVPESRVLDTLVHIWVSSIYNEIR--