For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTMPSPAPGSADPDNPTRQRILAATAEVLGRNGTTRLSLSEVAAQAGVSRPTLYRYFADKRELLDVFVVW ERQYYERAIAKATAELPAHERLDAALRVIVEYQLSYPGMRMVDVEPDQVIRRMSRVLPLMRERLERLCTG PDAALSAATAVRVAISQYLVRSDDSADFLAQLRHAARVRHPGR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4112 | - | - | 100% (183) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4118 | - | 4e-55 | 62.29% (175) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3637 | - | 7e-08 | 29.41% (102) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0482c | - | 9e-08 | 27.37% (179) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0472c | - | 9e-08 | 27.37% (179) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 3e-06 | 32.58% (89) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2046 | - | 2e-09 | 44.12% (68) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0389 | - | 3e-56 | 62.57% (179) | putative regulatory protein |
| M. avium 104 | MAV_5134 | - | 1e-56 | 61.33% (181) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2557 | - | 2e-66 | 74.23% (163) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0276 | - | 3e-63 | 74.05% (158) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_1039 | - | 7e-56 | 62.01% (179) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2233 | - | 2e-85 | 85.33% (184) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4112|M.gilvum_PYR-GCK MTMPSP--------APGSAD-PDNPTRQRILAATAEVLGRNGTTRLSLSE
Mvan_2233|M.vanbaalenii_PYR-1 MPQPPPGD-----RGPQSADDPDSPTRQRILAATAEVLGRNGTTKLSLSE
MSMEG_2557|M.smegmatis_MC2_155 MAGTDAG---------TDAGTEASSTRERILAATAKVLGSNGTTKLSLSD
TH_0276|M.thermoresistible__bu MP-----------------DRIAASARERILTATAEVLGRAGMTKLSLSD
MMAR_0389|M.marinum_M MSQAFG---------AIDTTDGDTSTRQRILAATAEVLARSGKTKLSLSE
MUL_1039|M.ulcerans_Agy99 MSQAFG---------AIDTTDGDTSMRQRILAATAEVLARSGKTKLSLSE
MAV_5134|M.avium_104 MSHPVR---------ATAIADTDTSTRQRILAATAEVLGRNGKTKLSLSD
Mb0482c|M.bovis_AF2122/97 MAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHG-RFLSMDE
Rv0472c|M.tuberculosis_H37Rv MAERIPAVTVKTDGRKRRWHQHKVERRNELVDGTIEAIRRHG-RFLSMDE
MAB_2046|M.abscessus_ATCC_1997 MPTEPVR------------VSFRRHVREKVLRATRELAIEKGWDQVRMSE
MLBr_00717|M.leprae_Br4923 MTTARR-------------RLSPEDRRAELLALGAEVFGKRPYDEVRIDE
*. * .:: : : :.:
Mflv_4112|M.gilvum_PYR-GCK VAAQAGVSRPTLYRYFADKRELLDVFVVWERQ--------YYERAIAKAT
Mvan_2233|M.vanbaalenii_PYR-1 VASQAGVSRPTLYRYFADKRELLDVFVVWERQ--------YYERAIARAT
MSMEG_2557|M.smegmatis_MC2_155 VASQAGVSRPTLYRWFSSKQDLLDAFVVWERR--------GYEQAVAQAT
TH_0276|M.thermoresistible__bu VAQQAGVSRPTLYRWFSGKEELLDAFAQWERQ--------MYERALAEAT
MMAR_0389|M.marinum_M VAAQAGVSRPTLYRWFASKEELLATFSRYERQ--------VFESGLSKAT
MUL_1039|M.ulcerans_Agy99 VAAQAGVSRPTLYRWFASKEELLATFSRYERQ--------VFESGLSKAT
MAV_5134|M.avium_104 VATQAGVSRPTLYRWFASKEELLSAFSAYERQ--------IFESGLVKAT
Mb0482c|M.bovis_AF2122/97 IAAEIGVSKTVLYRYFVDKNDLTTAVMMRFTQT------TLIPNMIAALS
Rv0472c|M.tuberculosis_H37Rv IAAEIGVSKTVLYRYFVDKNDLTTAVMMRFTQT------TLIPNMIAALS
MAB_2046|M.abscessus_ATCC_1997 VAESVGVSRPTLYKEFGDKQGLGDALVVSEGQRFMEGILAVLAEHVGDVR
MLBr_00717|M.leprae_Br4923 IAERAGVSRALMYHYFPDKRAFFAAVVKDEADR-------LYAATNIPPP
:* ***:. :*: * .*. : ..
Mflv_4112|M.gilvum_PYR-GCK AELPAHERLDAALR----VIVEYQLSYP-------------GMRMVDVEP
Mvan_2233|M.vanbaalenii_PYR-1 ADLPVSERLDAALR----VIVEYQLSYP-------------GLRMVDVEP
MSMEG_2557|M.smegmatis_MC2_155 GALPASERLDAALR----VIAEYQRSYP-------------GLRMVDIEP
TH_0276|M.thermoresistible__bu AGLPAEERLDAVLR----VIVEYQQSYP-------------GLRMVDIEP
MMAR_0389|M.marinum_M AGLKGVDKLDAALR----FIVDYQYSYS-------------GVRMVDIEP
MUL_1039|M.ulcerans_Agy99 AGLKGVDKLDAALR----FIVDYQYSYS-------------GVRMVDIEP
MAV_5134|M.avium_104 AGLKGVDKLDAVLR----FIVDYQHSYS-------------GVRMVDVEP
Mb0482c|M.bovis_AF2122/97 ADMDGFELTREIIR----VYVETVAAQPEPYRFVMA-NSSASKSKVIADS
Rv0472c|M.tuberculosis_H37Rv ADMDGFELTREIIR----VYVETVAAQPEPYRFVMA-NSSASKSKVIADS
MAB_2046|M.abscessus_ATCC_1997 GGITAAVQFTLCEAEDSPLLKAVLTSNPSGNDRGGS-SSTGVLPLLPTSA
MLBr_00717|M.leprae_Br4923 AGLTMFEEVRVGVL----AYMAYHKQNPEAAWAAYVGLGRSDPVLLGIDD
. : . : .
Mflv_4112|M.gilvum_PYR-GCK DQVIRRMSRVLPLMRERL-----ERLCTG--PDAALSAATAVRVAISQYL
Mvan_2233|M.vanbaalenii_PYR-1 DQVIKRLTRVLPLMRDRL-----QRLCTG--PDAALAAATAVRVAISQYL
MSMEG_2557|M.smegmatis_MC2_155 EHVIRRLSQIMPLLRERL-----QRLTTG--PDSDVAAATAVRVAISHYL
TH_0276|M.thermoresistible__bu AHLIGRLSAILPVMRDRL-----ERLCTG--PTASAAAATAVRVAVSHYL
MMAR_0389|M.marinum_M ELVISQMSGVIPEMREGL-----QRLLPG--PNAAVKAATAIRIAISHYI
MUL_1039|M.ulcerans_Agy99 ELVISQMSSVIPEMREGL-----QRLLPG--PNAAVKAATAIRIAISHYI
MAV_5134|M.avium_104 EHTIAQFSWVIPQMREGL-----QRHLPG--PNAAVKAATVIRIAISHYI
Mb0482c|M.bovis_AF2122/97 ERIIARMLAVMLRRRMQE-----AGMDTGGVEPWAYLIVGGVQLATHSWM
Rv0472c|M.tuberculosis_H37Rv ERIIARMLAVMLRRRMQE-----AGMDTGGVEPWAYLIVGGVQLATHSWM
MAB_2046|M.abscessus_ATCC_1997 SLLQLCSAALITWFNDHF-----DDLDPE---DVEEVADVLVRLTVSHVV
MLBr_00717|M.leprae_Br4923 EAKNRQMEHIMSRIGDVVSVVPESKLHPDIERDLRVIVHGWLAFTFEVCR
:: . : .:
Mflv_4112|M.gilvum_PYR-GCK VR----SDDSADFLAQLRHAA---------------RVRHPGR-------
Mvan_2233|M.vanbaalenii_PYR-1 VR----SDDSEQFLAQLRHAA---------------RVKHRDM-------
MSMEG_2557|M.smegmatis_MC2_155 VR----SDDADDFLAQLRHVA---------------RPRRRE--------
TH_0276|M.thermoresistible__bu VQ----SDDAGDFLAQLRHAVGLPIAPGAVSAKTPLQPRRNP--------
MMAR_0389|M.marinum_M VR----SDDADQFLAQLRHAVG---------------LKGG---------
MUL_1039|M.ulcerans_Agy99 VR----SDDADQFLAQLRHAVG---------------LKGG---------
MAV_5134|M.avium_104 VR----SDDADQFLAQLRHAVG---------------IKAPTD-------
Mb0482c|M.bovis_AF2122/97 SDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQ
Rv0472c|M.tuberculosis_H37Rv SDPRMSSDELIDYLTMLSWSALCGIVEAGGSLEKFREQPHPSPIVPAWGQ
MAB_2046|M.abscessus_ATCC_1997 LP----AADIATTGERISRVALR-----------YLGVVHSL--------
MLBr_00717|M.leprae_Br4923 QRIMDPSTDADRLADSCAHALLDAIARVPEISKELADAMAIARQPPQ---
: :
Mflv_4112|M.gilvum_PYR-GCK -
Mvan_2233|M.vanbaalenii_PYR-1 -
MSMEG_2557|M.smegmatis_MC2_155 -
TH_0276|M.thermoresistible__bu -
MMAR_0389|M.marinum_M -
MUL_1039|M.ulcerans_Agy99 -
MAV_5134|M.avium_104 -
Mb0482c|M.bovis_AF2122/97 V
Rv0472c|M.tuberculosis_H37Rv V
MAB_2046|M.abscessus_ATCC_1997 -
MLBr_00717|M.leprae_Br4923 -