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MSHPVRATAIADTDTSTRQRILAATAEVLGRNGKTKLSLSDVATQAGVSRPTLYRWFASKEELLSAFSAY ERQIFESGLVKATAGLKGVDKLDAVLRFIVDYQHSYSGVRMVDVEPEHTIAQFSWVIPQMREGLQRHLPG PNAAVKAATVIRIAISHYIVRSDDADQFLAQLRHAVGIKAPTD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5134 | - | - | 100% (183) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_2588 | - | 1e-09 | 39.00% (100) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_3517 | - | 1e-08 | 33.33% (81) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2184c | - | 2e-07 | 33.33% (93) | hypothetical protein Mb2184c |
| M. gilvum PYR-GCK | Mflv_4118 | - | 3e-64 | 68.26% (167) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 7e-06 | 32.14% (84) | transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 3e-05 | 37.50% (48) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4541 | - | 9e-09 | 29.73% (111) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0389 | - | 9e-79 | 83.24% (179) | putative regulatory protein |
| M. smegmatis MC2 155 | MSMEG_2553 | - | 5e-66 | 73.96% (169) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0275 | - | 3e-70 | 72.93% (181) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_1039 | - | 4e-78 | 82.68% (179) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2227 | - | 2e-65 | 70.18% (171) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0389|M.marinum_M ----MSQAFGAIDTTDGDTSTRQRILAATAEVLARSGKTKLSLSEVAAQA
MUL_1039|M.ulcerans_Agy99 ----MSQAFGAIDTTDGDTSMRQRILAATAEVLARSGKTKLSLSEVAAQA
MAV_5134|M.avium_104 ----MSHPVRATAIADTDTSTRQRILAATAEVLGRNGKTKLSLSDVATQA
Mflv_4118|M.gilvum_PYR-GCK ----MNQPADDAQTPDD-VSTRQRILAATAEVLGRSGQTKLSLSEVALQA
Mvan_2227|M.vanbaalenii_PYR-1 ----MNEPASDAAAAED-TSTRHRILVATAEVLSRSGQTKLSLSEVALQA
MSMEG_2553|M.smegmatis_MC2_155 ----MNEALP-AGAGAD-TSTRHRILVATAEVLARSGQTKLSLSEVALQA
TH_0275|M.thermoresistible__bu ----VNQPTDQQAAPEEEASTRHRILEATAEVLSRAGKRKLSLSEVALQA
Mb2184c|M.bovis_AF2122/97 -----------MPSADVGRQTRAQILRAAMDIASVKGLSGLSIGELAGRL
MLBr_02568|M.leprae_Br4923 --------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTSMDAIAAEA
Rv1534|M.tuberculosis_H37Rv -MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFHATTVADIAKQA
MAB_4541|M.abscessus_ATCC_1997 MTNLIPESETPNKRERAKADRRDQLLRAAARLLAMRGYARVRLEDLGSAV
. .:* *: : . * : :.
MMAR_0389|M.marinum_M GVSRPTLYRWFASKEELLATFSRYERQVFESGLSK-ATAGLKGVDK----
MUL_1039|M.ulcerans_Agy99 GVSRPTLYRWFASKEELLATFSRYERQVFESGLSK-ATAGLKGVDK----
MAV_5134|M.avium_104 GVSRPTLYRWFASKEELLSAFSAYERQIFESGLVK-ATAGLKGVDK----
Mflv_4118|M.gilvum_PYR-GCK GVSRPTLYRWFADKQALLEAFGVHEREMFETGILK-ATAGLRGTER----
Mvan_2227|M.vanbaalenii_PYR-1 GVSRPTLYRWFADKPALLEAFGIYEREMFETGIAK-ATAGLRGNDR----
MSMEG_2553|M.smegmatis_MC2_155 GVSRPTLYRWFADKQELLEAFGNYEREMFDNGIGR-ATAGLRGNEK----
TH_0275|M.thermoresistible__bu GVSRPTLYRWFASKEDLLDAFGAYERQLFDTGISK-ATAGLRGNEK----
Mb2184c|M.bovis_AF2122/97 GMSKSGLFRHFGAKEQLQLATVEAAVSVFEAEVVAPAMAAPPGVDR----
MLBr_02568|M.leprae_Br4923 QISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFTQSPKDL----
Rv1534|M.tuberculosis_H37Rv GLAYGLIYWYFDSKDDLFHALMAGEEEALRAHVAAELARVGGSTEAPLRA
MAB_4541|M.abscessus_ATCC_1997 GISGPAIYRHFPNKEALLVDLLTDVSRRLLEGGMTVAAAASSPAEA----
:: :: : * * : :
MMAR_0389|M.marinum_M -LDAALRFIVDYQYS--------YSG-------VRMVDIEPELVISQMSG
MUL_1039|M.ulcerans_Agy99 -LDAALRFIVDYQYS--------YSG-------VRMVDIEPELVISQMSS
MAV_5134|M.avium_104 -LDAVLRFIVDYQHS--------YSG-------VRMVDVEPEHTIAQFSW
Mflv_4118|M.gilvum_PYR-GCK -VDAAMRFIVEYQQS--------YSG-------VRLVDIEPEVVISRLAH
Mvan_2227|M.vanbaalenii_PYR-1 -VDAAMRFIVDYQQS--------YSG-------VRLVDIEPEVVIGRLAH
MSMEG_2553|M.smegmatis_MC2_155 -LDAALRFIVQYQQS--------YSG-------VRLVDIEPEVVIAQLAH
TH_0275|M.thermoresistible__bu -LDAALRFIVEYQHS--------YSG-------VRLVDIEPEVVIAQLSQ
Mb2184c|M.bovis_AF2122/97 -VRALMHAWVGYLERD------VFPGGCFFAAAAADVDSQPGPVRDRIAA
MLBr_02568|M.leprae_Br4923 -LRNTIVSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQITELVAG
Rv1534|M.tuberculosis_H37Rv LLQAAVQATFEFFETDKATVKLLFRDAYALG--GRFEEHLGGIYERFIDD
MAB_4541|M.abscessus_ATCC_1997 -LDGLIDFHLDFALNE--------SDLIRVQ--DRDLDSLPENARRQVRQ
: : . : .
MMAR_0389|M.marinum_M V----IPEMREGLQRLLP-GPNAAVKAATAIRIAISHYIVRSD------D
MUL_1039|M.ulcerans_Agy99 V----IPEMREGLQRLLP-GPNAAVKAATAIRIAISHYIVRSD------D
MAV_5134|M.avium_104 V----IPQMREGLQRHLP-GPNAAVKAATVIRIAISHYIVRSD------D
Mflv_4118|M.gilvum_PYR-GCK I----IPLMRAQLEKLLP-GANGAVKAATAVRVAVCHYIVRAD------D
Mvan_2227|M.vanbaalenii_PYR-1 I----IPAMRAQLEKLLP-GPNGAVKAATAIRVAVSHYIVRAD------D
MSMEG_2553|M.smegmatis_MC2_155 V----IPIMRARLLKLLS-GPNAAVKAATAIRVAISHYIVRSD------D
TH_0275|M.thermoresistible__bu V----IPVMRARLQRLLP-GANGAVKAATAIRVAVSHYIVRSD------D
Mb2184c|M.bovis_AF2122/97 TGRAGIAAITADVETAQRRGEIRADIEARQLAFELHAYAMEANWALLLLD
MLBr_02568|M.leprae_Br4923 LMRVGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEA-------
Rv1534|M.tuberculosis_H37Rv IEAVVVAAQRRGEVVEAPSRMAAYTLAALVGQLAHRRLNTDDN-VTAAQV
MAB_4541|M.abscessus_ATCC_1997 YQRRYVEAWVQVLCRSQQGLDESDARIKAHAAFGLMNSTPYSA-------
.
MMAR_0389|M.marinum_M ADQFLAQLRHAVGLKGG------------
MUL_1039|M.ulcerans_Agy99 ADQFLAQLRHAVGLKGG------------
MAV_5134|M.avium_104 ADQFLAQLRHAVGIKAPTD----------
Mflv_4118|M.gilvum_PYR-GCK DDQFLAQLRHAVGLRATD-----------
Mvan_2227|M.vanbaalenii_PYR-1 DDQFLAQLRHSVGIKPS------------
MSMEG_2553|M.smegmatis_MC2_155 ADQFLAQLRHAVGIRQTDTN---------
TH_0275|M.thermoresistible__bu DDQFLAQLRHAVGIKAPAGEPAPAR----
Mb2184c|M.bovis_AF2122/97 DDGAGERARTAIDAALARVGTTQEGVES-
MLBr_02568|M.leprae_Br4923 AELMINLFWHGLKGAPADRDFGPSIVAG-
Rv1534|M.tuberculosis_H37Rv ADFVVSLVLDGLRPRALAVGARGGRAART
MAB_4541|M.abscessus_ATCC_1997 GRSAPSQTRTVLRQMVVAALRS-------
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