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M. thermoresistible (build 8) TH_4304 (-)

annotation: propionyl-CoA carboxylase beta chain
coordinates: 538636 - 540231
length: 532

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_4304--100% (532)propionyl-CoA carboxylase beta chain
M. thermoresistible (build 8)TH_1608-e-14249.91% (527) PROBABLE PROPIONYL-CoA CARBOXYLASE BETA CHAIN 4 ACCD4 (PCCASE)
M. thermoresistible (build 8)TH_2704-e-10243.79% (459) PUTATIVE propionyl-CoA carboxylase beta chain

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3308accD50.088.87% (530) propionyl-CoA carboxylase beta chain
M. gilvum PYR-GCKMflv_4774-0.090.94% (530) carboxyl transferase
M. tuberculosis H37RvRv3280accD50.089.06% (530) propionyl-CoA carboxylase beta chain
M. leprae Br4923MLBr_00731accD50.086.42% (530) acetyl/propionyl CoA carboxylase beta subunit
M. abscessus ATCC 19977MAB_3631-0.088.30% (530) propionyl-CoA carboxylase beta chain 5 AccD5
M. marinum MMMAR_1256accD50.088.30% (530) propionyl-CoA carboxylase beta chain 5 AccD5
M. avium 104MAV_4250-0.090.19% (530) propionyl-CoA carboxylase beta chain
M. smegmatis MC2 155MSMEG_1813-0.090.94% (530) propionyl-CoA carboxylase beta chain
M. ulcerans Agy99MUL_2632accD50.087.74% (530) propionyl-CoA carboxylase beta chain 5 AccD5
M. vanbaalenii PYR-1Mvan_1677-0.090.57% (530) carboxyl transferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3308|M.bovis_AF2122/97            MTSVTDRSAHSAERSTEHTIDIHTTAGKLAELHKRREESLHPVGEDAVEK
Rv3280|M.tuberculosis_H37Rv         MTSVTDRSAHSAERSTEHTIDIHTTAGKLAELHKRREESLHPVGEDAVEK
MLBr_00731|M.leprae_Br4923          MTSVTDHSAHSMERAAEHTINIHTTAGKLAELHKRTEEALHPVGAAAFEK
MMAR_1256|M.marinum_M               MTSVTD---HTAEPAAEHTIDIHTTAGKLAELHKRRAESLHPVGEGAIEK
MUL_2632|M.ulcerans_Agy99           MTSVTD---HTAEPAAEHTIDIHTTAGKLAELHKRRAESLHPVGEGAIEK
MAV_4250|M.avium_104                MTSVTD---HTAEPAAEHSIDIHTTAGKLAELHKRREESLHPVGEEAVEK
Mflv_4774|M.gilvum_PYR-GCK          ---MTE-------PEASHEIDIHTTAGKLADLRKRAEEALHPVGEAAVEK
Mvan_1677|M.vanbaalenii_PYR-1       MTSVTE-------PSAEHEIDIHTTAGKLADLRKRAAEAQHPVGETAVEK
MSMEG_1813|M.smegmatis_MC2_155      MTSVTE-------PSAEHQVDIHTTAGKLADLKRRTEETLHPVGEAAVDK
TH_4304|M.thermoresistible__bu      ------------------VVDLRTTAGKLADLRRRKAEAQFPVGEAAVEK
MAB_3631|M.abscessus_ATCC_1997      -MTTTESDSHTAADAAAPQPDIHTTAGKLADLRRRNEEALHPVGEAAVDK
                                                        :::*******:*::*  *: .***  *.:*

Mb3308|M.bovis_AF2122/97            VHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVT
Rv3280|M.tuberculosis_H37Rv         VHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFNLGEKRPLGDGVVT
MLBr_00731|M.leprae_Br4923          VHAKGKFTARERIYALLDDDSFVELDALARHRSTNFGLGENRPVGDGVVT
MMAR_1256|M.marinum_M               VHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFGLESNRPVGDGVVT
MUL_2632|M.ulcerans_Agy99           VHAKGKLTARERIYALLDEDSFVELDALAKHRSTNFGLESNRPVGDGVVT
MAV_4250|M.avium_104                VHAKGKLTARERILALLDEDSFVELDALARHRSKNFGLENNRPLGDGVIT
Mflv_4774|M.gilvum_PYR-GCK          VHAKGKLTARERILALLDEGSFVELDALAKHRSKNFGLEKNRPTGDGVVT
Mvan_1677|M.vanbaalenii_PYR-1       VHAKGKLTARERILALLDEGSFVELDALAKHRSKNFGLEHNRPTGDGVVT
MSMEG_1813|M.smegmatis_MC2_155      VHAKGKLTARERILALLDEGSFVELDALAKHRSTNFGLEKNRPLGDGVIT
TH_4304|M.thermoresistible__bu      VHAKGKLTARERVLALLDEGSFVELDQLARHRSTNFGLADKRPLGDGVVT
MAB_3631|M.abscessus_ATCC_1997      IHAKGKLTARERIFALLDEGSFVELDALARHRSTNFGLESKRPLGDGVVT
                                    :*****:*****: ****:.****** **:***.**.*  :** ****:*

Mb3308|M.bovis_AF2122/97            GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
Rv3280|M.tuberculosis_H37Rv         GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
MLBr_00731|M.leprae_Br4923          GYGTIDGRDVCIFSQDVTVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
MMAR_1256|M.marinum_M               GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAVKTGRPLIGIN
MUL_2632|M.ulcerans_Agy99           GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAVKTGRPLIGIN
MAV_4250|M.avium_104                GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
Mflv_4774|M.gilvum_PYR-GCK          GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
Mvan_1677|M.vanbaalenii_PYR-1       GYGTIDGRDVCVFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
MSMEG_1813|M.smegmatis_MC2_155      GYGTIDGRDVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
TH_4304|M.thermoresistible__bu      GYGTIDGREVCIFSQDATVFGGSLGEVYGEKIVKVQELAIKTGRPLIGIN
MAB_3631|M.abscessus_ATCC_1997      GFGTIDGRDVCIFSQDVSVFGGSLGEVYGEKIVKVMDLAIKTGRPLIGIN
                                    *:******:**:****.:***************** :**:**********

Mb3308|M.bovis_AF2122/97            DGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPA
Rv3280|M.tuberculosis_H37Rv         DGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPA
MLBr_00731|M.leprae_Br4923          DGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPA
MMAR_1256|M.marinum_M               DGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPA
MUL_2632|M.ulcerans_Agy99           DGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPA
MAV_4250|M.avium_104                DGAGARIQEGVVSLGLYSRIFRNNILASGVIPQISLIMGAAAGGHVYSPA
Mflv_4774|M.gilvum_PYR-GCK          DGAGARIQEGVVSLGLYSKIFHNNIKASGVIPQISLIMGAAAGGHVYSPA
Mvan_1677|M.vanbaalenii_PYR-1       DGAGARIQEGVVSLGLYSRIFHNNIKASGVIPQISLIMGAAAGGHVYSPA
MSMEG_1813|M.smegmatis_MC2_155      DGAGARIQEGVVSLGLYSRIFHNNIKASGVIPQISLIMGAAAGGHVYSPA
TH_4304|M.thermoresistible__bu      DGAGARIQEGVVSLSLYSRIFHNNIRASGVIPQISLIMGAAAGGHVYSPA
MAB_3631|M.abscessus_ATCC_1997      EGAGARIQEGVVSLGLYGQIFHRNVIASGVIPQISLIMGPAAGGHVYSPA
                                    :*************.**.:**:.*: *************.**********

Mb3308|M.bovis_AF2122/97            LTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHY
Rv3280|M.tuberculosis_H37Rv         LTDFVIMVDQTSQMFITGPDVIKTVTGEEVTMEELGGAHTHMAKSGTAHY
MLBr_00731|M.leprae_Br4923          LTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTAHY
MMAR_1256|M.marinum_M               LTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMVKSGTAHY
MUL_2632|M.ulcerans_Agy99           LTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEEIGGAHTHMVKSGTAHY
MAV_4250|M.avium_104                LTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTLHY
Mflv_4774|M.gilvum_PYR-GCK          LTDFVIMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTVHY
Mvan_1677|M.vanbaalenii_PYR-1       LTDFVIMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTVHY
MSMEG_1813|M.smegmatis_MC2_155      LTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTAHY
TH_4304|M.thermoresistible__bu      LTDFVIMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTAHY
MAB_3631|M.abscessus_ATCC_1997      LTDFVVMVDQTSQMFITGPDVIKTVTGEDVTMEELGGAHTHMAKSGTAHY
                                    *****:**********************:*****:*******.**** **

Mb3308|M.bovis_AF2122/97            AASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPT-GPIEENLTDEDLE
Rv3280|M.tuberculosis_H37Rv         AASGEQDAFDYVRELLSYLPPNNSTDAPRYQAAAPT-GPIEENLTDEDLE
MLBr_00731|M.leprae_Br4923          VASGEQDAFDWVRDVLSYLPSNNFTDAPRYSKPVPH-GSIEDNLTAKDLE
MMAR_1256|M.marinum_M               VASGEQDAFEYVRELLSYLPPNNATDAPRYPAPAPE-GPIEENLTDEDLE
MUL_2632|M.ulcerans_Agy99           VASGEQDAFEYVRELLSYLPPNNATDAPRYPAPAPE-GPIEENLTDEDLE
MAV_4250|M.avium_104                VASGEQDAFDWVRDLLSYLPPNNATDPPRYAEPHPA-GAIEDNLTDEDLE
Mflv_4774|M.gilvum_PYR-GCK          VASGEQDALDYVRDLLSYLPPNNYAEPPRYPAPIS--GPIEENLTDEDLE
Mvan_1677|M.vanbaalenii_PYR-1       VASGEQDALDYVRDLLSYLPPNNYAEPPRYPAPHAD-APIEESLTDEDLE
MSMEG_1813|M.smegmatis_MC2_155      VASGEQDAFDYVRDLLSYLPPNNYADPPLYPVAIPE-GSIEETLTDEDLE
TH_4304|M.thermoresistible__bu      VASGEQDAFDYVRDLLSYLPPNNYADPPRYPAPVQH-GAIEDNLTDTDLE
MAB_3631|M.abscessus_ATCC_1997      VASGEQDAFDYVRDILSYLPSNNASEPPRYPGPEPTDGAIEDHLTEEDLE
                                    .*******:::**::*****.** ::.* *  .    ..**: **  ***

Mb3308|M.bovis_AF2122/97            LDTLIPDSPNQPYDMHEVITRLLDD-EFLEIQAGYAQNIVVGFGRIDGRP
Rv3280|M.tuberculosis_H37Rv         LDTLIPDSPNQPYDMHEVITRLLDD-EFLEIQAGYAQNIVVGFGRIDGRP
MLBr_00731|M.leprae_Br4923          LDTLIPDSPNQPYDMHEVVTRLLDEEEFLEVQAGYATNIVVGLGRIDDRP
MMAR_1256|M.marinum_M               LDTLIPDSPNQPYDMHEVITRILDEDEFLEIQAGYAQNIVVGFGRIEGRP
MUL_2632|M.ulcerans_Agy99           LDTLIPDSPNQPYDMHEVITRILDEDEFLEIQAGYAQNIVVGFGRIEGRP
MAV_4250|M.avium_104                LDTLIPDSPNQPYDMHEVITRILDDDEFLEIQGGYAQNIVVGFGRIDGRP
Mflv_4774|M.gilvum_PYR-GCK          LDTLIPDSPNQPYDMHEVITRILDDDEFLEVQAGYAGNIVVGFGRVDGRP
Mvan_1677|M.vanbaalenii_PYR-1       LDTLIPDSPNQPYDMHEVITRILDDDEFLEVQAGYAGNIVIGFGRVDGRP
MSMEG_1813|M.smegmatis_MC2_155      LDTLIPDSPNQPYDMHEVITRILDDDEFLEVQAGYAGNIVVGFGRVEGRP
TH_4304|M.thermoresistible__bu      LDTLIPDSPNQPYDMHEVITRILDDDEFLEVQAGYAQNIIVGFGRVDGRP
MAB_3631|M.abscessus_ATCC_1997      LDTLIPDSPNQPYDMHEVITRILDDDEFLEVQAGYAQNIIVGFGRIDGRS
                                    ******************:**:**: ****:*.*** **::*:**::.*.

Mb3308|M.bovis_AF2122/97            VGIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGT
Rv3280|M.tuberculosis_H37Rv         VGIVANQPTHFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGT
MLBr_00731|M.leprae_Br4923          VGIVANQPIQFAGCLDINASEKAARFVRVCDCFNIPIVMLVDVPGFLPGT
MMAR_1256|M.marinum_M               VGIVANQPTHFAGCLDIDASEKAARFVRTCDCFNIPIVMLVDVPGFLPGT
MUL_2632|M.ulcerans_Agy99           VGIVANQPTHFAGCLDIDASEKAARFVRTCDCFNIPIVMLVDVPGFLPGT
MAV_4250|M.avium_104                VGIVANQPTQFAGCLDINASEKAARFVRTCDCFNIPIIMLVDVPGFLPGT
Mflv_4774|M.gilvum_PYR-GCK          VGIVANQPTQFAGCLDINASEKAARFIRTCDCYNIPIVLLVDVPGFLPGT
Mvan_1677|M.vanbaalenii_PYR-1       VGIVANQPTQFAGCLDINASEKAARFIRTCDCFNIPIVLLVDVPGFLPGT
MSMEG_1813|M.smegmatis_MC2_155      VGIVANQPTQFAGCLDINASEKAARFIRTCDCFNIPIVLLVDVPGFLPGT
TH_4304|M.thermoresistible__bu      VGIVANQPTQFAGCLDINASEKAARFVRTCDCFNIPIVMLVDVPGFLPGT
MAB_3631|M.abscessus_ATCC_1997      VGIVANQPTQFAGCLDINASEKAARFIRTCDCFGIPIITLEDVPGFLPGT
                                    ******** :*******:********:*.***:.***: * *********

Mb3308|M.bovis_AF2122/97            DQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDA
Rv3280|M.tuberculosis_H37Rv         DQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDV
MLBr_00731|M.leprae_Br4923          EQEYDGIIRRGAKLLFAYGEATVPKITVITRKAYGGAYCVMGSKNMGCDV
MMAR_1256|M.marinum_M               GQEYNGIIRRGAKLLYAYGEATVPKVTVITRKAYGGAYCVMGSKDMGCDV
MUL_2632|M.ulcerans_Agy99           GQEYNGIIRRGAKLLYAYGEATVPKVTVITRKAYGGAYCVMGSKDMGCDV
MAV_4250|M.avium_104                GQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYCVMGSKDMGCDV
Mflv_4774|M.gilvum_PYR-GCK          DQEYNGIIRRGAKLLYAYGEATVAKVTVITRKSYGGAYCVMGSKDMGADV
Mvan_1677|M.vanbaalenii_PYR-1       DQEYNGIIRRGAKLLYAYGEATVAKVTVITRKSYGGAYCVMGSKDMGADV
MSMEG_1813|M.smegmatis_MC2_155      DQEYNGIIRRGAKLLYAYGEATVAKVTVITRKSYGGAYCVMGSKDMGADV
TH_4304|M.thermoresistible__bu      DQEYNGIIRRGAKLLYAYGEATVAKITVITRKAYGGAYCVMGSKDMGADV
MAB_3631|M.abscessus_ATCC_1997      EQEYNGIIRRGAKLLYAYGEATVPKITVITRKAYGGAYDVMGSKHMGADV
                                     ***:**********:*******.*:******:***** *****.**.*.

Mb3308|M.bovis_AF2122/97            NLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDT
Rv3280|M.tuberculosis_H37Rv         NLAWPTAQIAVMGASGAVGFVYRQQLAEAAANGEDIDKLRLRLQQEYEDT
MLBr_00731|M.leprae_Br4923          NLAWPTAQIAVMGASGAVGFVYRKELAQAAKNGANVDELRLQLQQEYEDT
MMAR_1256|M.marinum_M               NLAWPTAQIAVMGASGAVGFVYRQQLKEAAEAGKDVDALRLQLQQEYEDT
MUL_2632|M.ulcerans_Agy99           NLAWPTAQIAVMGASGAVGFVYRQQLKKAAEAGKDVDALLLQLQQEYEDT
MAV_4250|M.avium_104                NIAWPSAQIAVMGASGAVGFVYRKQLAEAAKKGEDVDALRLQLQQEYEDT
Mflv_4774|M.gilvum_PYR-GCK          VVAWPTAQIAVMGASGAVGFVYRGQLKEAAANGEDVDALRLKLQQEYEDT
Mvan_1677|M.vanbaalenii_PYR-1       VVAWPTAQIAVMGASGAVGFVYRQQLREAAANGEDVDALRLKLQQEYEDT
MSMEG_1813|M.smegmatis_MC2_155      VVAWPTAQIAVMGASGAVGFVYRQQLKEAAKNGEDVDALRLELQQTYEDT
TH_4304|M.thermoresistible__bu      CVAWPTAQIAVMGASGAVGFVYRPQLAEAAKKGEDVDALRLRLQQEYEDT
MAB_3631|M.abscessus_ATCC_1997      NVAWPTAQIAVMGASGAVGFVYRSQLAEAAKNGDDVDALRLQLQAEYEDT
                                     :***:***************** :* :**  * ::* * *.**  ****

Mb3308|M.bovis_AF2122/97            LVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL
Rv3280|M.tuberculosis_H37Rv         LVNPYVAAERGYVDAVIPPSHTRGYIGTALRLLERKIAQLPPKKHGNVPL
MLBr_00731|M.leprae_Br4923          LVNPYIAAERGYVDAVIPPSHTRGYIATALHLLERKIAHLPPKKHGNIPL
MMAR_1256|M.marinum_M               LVNPYIAAERGYVDAVIPPSYTRGYIGTALRLLERKIAQQPPKKHGNIPL
MUL_2632|M.ulcerans_Agy99           LVNPYIAAERGYVDAVIPPSYTRGYIGTALRLLERKIAQQPPKKHGNIPL
MAV_4250|M.avium_104                LVNPYVAAERGYVDAVIPPSHTRGYIATALRLLERKIAHLPPKKHGNIPL
Mflv_4774|M.gilvum_PYR-GCK          LVNPYIAAERGYVDAVIPPSHTRGYVATALKLLERKVVQTPPKKHGNIPL
Mvan_1677|M.vanbaalenii_PYR-1       LVNPYIAAERGYVDAVILPSHTRGYVATALKLLERKVVQTPPKKHGNIPL
MSMEG_1813|M.smegmatis_MC2_155      LVNPYIAAERGYVDAVIPPSHTRGYVANALRLLERKIVQMPPKKHGNIPL
TH_4304|M.thermoresistible__bu      LVNPYIAAERGYVDAVIPPSHTRGYIATSLRLLERKIAQVPPKKHGNIPL
MAB_3631|M.abscessus_ATCC_1997      LVNPYIAAERGYVDAVIPPSHTRGYIATSLRLLDRKIVRLPPKKHGNIPL
                                    *****:*********** **:****:..:*:**:**:.: *******:**