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M. tuberculosis H37Rv Rv3773c (-)

annotation: hypothetical protein Rv3773c
coordinates: 4218241 - 4218825
length: 194

PPESRPGPDSPPTDELACAEAALQVLQQVLHTIGRQDKAKQTPCPGYDVKKLTEHLLNSIMVLGGMVGAE
FSLRADIDSVERLVSGAARSALDAWHRHGLEGDVSLGPGSMSAKVAVSVFSVEFLVHAWDYAVAVGSELK
AADSLAEYVLELARKLIKPEERSVAGFNEPVDVPEDGGALERLIAFTGRNPAR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3773c--100% (194)hypothetical protein Rv3773c
M. tuberculosis H37RvRv0576-2e-4447.40% (192) ArsR family transcriptional regulator
M. tuberculosis H37RvRv1727-7e-1230.00% (180) hypothetical protein Rv1727

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3801c-2e-60100.00% (114) hypothetical protein Mb3801c
M. gilvum PYR-GCKMflv_1118-3e-0829.01% (162) hypothetical protein Mflv_1118
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4446-1e-3543.89% (180) hypothetical protein MAB_4446
M. marinum MMMAR_5328-2e-6966.49% (194) hypothetical protein MMAR_5328
M. avium 104MAV_0248-3e-6158.97% (195) hypothetical protein MAV_0248
M. smegmatis MC2 155MSMEG_6832-2e-3338.80% (183) hypothetical protein MSMEG_6832
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_4409-1e-6764.95% (194) hypothetical protein MUL_4409
M. vanbaalenii PYR-1Mvan_2932-7e-1027.23% (213) hypothetical protein Mvan_2932

CLUSTAL 2.0.9 multiple sequence alignment


Rv3773c|M.tuberculosis_H37Rv        ---------MPPESRPGPDSPPTDELACAEAALQVLQQVLHTIGRQDKAK
Mb3801c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_5328|M.marinum_M               ---------MASDLRPGPDSPPTDELASAERALAVLQQVLHPIGDGDLFR
MUL_4409|M.ulcerans_Agy99           ---------MASDLRPGPDSPPTDELASAERALAVLQQVLHPIGDGDLFR
MAV_0248|M.avium_104                ------MANMAPDLRPGPDSPPTDELDGAEAALRVMQQVLHPIAADDMPR
MSMEG_6832|M.smegmatis_MC2_155      -------MTYAGARASTPHWADMDELSSAQSALSALRPVLSAITPDDCGL
MAB_4446|M.abscessus_ATCC_1997      ---------MTTALNP---------LETVANARAALHEVVSRLTEADNDK
Mflv_1118|M.gilvum_PYR-GCK          -------------------------MIDMTAACAGTAGLLDRVRDDQLSG
Mvan_2932|M.vanbaalenii_PYR-1       MTGLGRHNGAMIAPTSSTTDHLKDPRPILDRAIATGGVVIAGVRPEQLTD
                                                                                      

Rv3773c|M.tuberculosis_H37Rv        QTPCPGYDVKKLTEHLLNSIMVLGGMVGAEFS-----LRADIDSVER---
Mb3801c|M.bovis_AF2122/97           --------------------------------------------MER---
MMAR_5328|M.marinum_M               PTPCPEYDVSGLTGHLLNSIVVLGGMAGAEFT-----MRDHTSSAEG---
MUL_4409|M.ulcerans_Agy99           PTPCPEYDVSGLTGHLLNSIVVLDGMAGAEFT-----MRDHTSTPEG---
MAV_0248|M.avium_104                PTPCAQFDVTRLTDHLLKSLEALGGMAGADFPD----HADSADSVER---
MSMEG_6832|M.smegmatis_MC2_155      PTPCAGFDVAALGEHLVGTVRMVGAAADAGFVRF--EVVSHDDDIEA---
MAB_4446|M.abscessus_ATCC_1997      QTPNAKFTVAQLTDHLQNSIKLLGGAAGVDIA------LTTEGSVAD---
Mflv_1118|M.gilvum_PYR-GCK          ATPCSGMDLGALVAHIGGLALAFDAAARKEFGPLTDTPPEMGDGVEDGWR
Mvan_2932|M.vanbaalenii_PYR-1       PTPCTDMDVRALLAHLIGVLARVAALGNGENP----FAVTETSVADDRWL
                                                                                      

Rv3773c|M.tuberculosis_H37Rv        -LVSGAARSALDAWHR-HGLEGDVSLGPGSMSAKVAVSVFSVEFLVHAWD
Mb3801c|M.bovis_AF2122/97           -LVSGAARSALDAWHR-HGLEGDVSLGPGSMSAKVAVSVFSVEFLVHAWD
MMAR_5328|M.marinum_M               -QVVSAARPALDAWHR-RGMEGDVPLGPASMPARVAVSVFSIEFLVHAWD
MUL_4409|M.ulcerans_Agy99           -QVVSAARPALDAWHR-RGMDGDVPLGPASMPARVAVSVFSIEFLVHAWD
MAV_0248|M.avium_104                -RVIAVARPALDAWRQ-RGLDGTVSFGGGEMPARNACAILALELLVHAWD
MSMEG_6832|M.smegmatis_MC2_155      -RVAASTEAVIAVWQR-RGTAGEVVFAGRVMPARLALGVLSVELVVHGWD
MAB_4446|M.abscessus_ATCC_1997      -RLLPQSQAVVDAWQR-RGIDGTVTLPIGEYPAEVAVRILGSEFLVHAWD
Mflv_1118|M.gilvum_PYR-GCK          ESYPSRLASLASAWREPAAWEGMSRAGGVDFPADVGGLIALTEVVVHGWD
Mvan_2932|M.vanbaalenii_PYR-1       DAWRQSGRRAADAWSDDAVLERPMALPWIQGSGAEVLASYFSELTVHTWD
                                                .*                 ..         *. ** **

Rv3773c|M.tuberculosis_H37Rv        YAVAVGSELKAADSLAEYVLELARKLIKPE---------------ERSVA
Mb3801c|M.bovis_AF2122/97           YAVAVGSELKAADSLAEYVLELARKLIKPE---------------ERSVA
MMAR_5328|M.marinum_M               YATAVGHDIHVPDSLADYVLGLAQNLIQPH---------------ERGAA
MUL_4409|M.ulcerans_Agy99           YATAVGHDIHVPDSLADYVLGLAQNLIQPH---------------ERGAA
MAV_0248|M.avium_104                YARAVGRDARAPEPLAEYVLGLAHRVIRPE---------------VRGQA
MSMEG_6832|M.smegmatis_MC2_155      FAQALHRPLGITAAHADFVLAMARHIITPA---------------SRETA
MAB_4446|M.abscessus_ATCC_1997      YAVATGQEFEPMDALTDGVLESVRMIIQPE---------------RRDGD
Mflv_1118|M.gilvum_PYR-GCK          VAVSAGLPYEVDGETLAAVHGHLAAFTADG---------------PVEG-
Mvan_2932|M.vanbaalenii_PYR-1       LATATRQQPDWDDTVVAAAFDAARQILPAENRRALYEEISAARGLDEVAV
                                     * :              .      .                        

Rv3773c|M.tuberculosis_H37Rv        GFNEPVDVPEDGGALERLIAFTGRNPAR--------
Mb3801c|M.bovis_AF2122/97           GFNEPVDVPEDGGALERLIAFTGRNPAR--------
MMAR_5328|M.marinum_M               GFDDPVQVGDDVSGLHRLVAFTGRNPIR--------
MUL_4409|M.ulcerans_Agy99           GFDDPVQVGDDVRGLHRLVAFTGRNPIR--------
MAV_0248|M.avium_104                GFDDPVEVPADADALTKLVAFTGRNPAR--------
MSMEG_6832|M.smegmatis_MC2_155      GFDDPVSVAADAAALDRLVAYTGRTPRRWPSNMKSR
MAB_4446|M.abscessus_ATCC_1997      FFADEVPVPDDSPNLVKLIAFTGRNPGWSPAS----
Mflv_1118|M.gilvum_PYR-GCK          LFDAPVPVPDDAPLLDRVIAMTGRDPSWSAA-----
Mvan_2932|M.vanbaalenii_PYR-1       PFAEAVPISDDAPAIDRLVAWNGRDPLRRF------
                                     *   * :  *   : :::* .** *